Browsing Articles (Departament de Tecnologies de la Informació i les Comunicacions) by Author "Trakoshis, Stavros"

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mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity

Pagani, Marco; Barsotti, Noemi; Bertero, Alice; Trakoshis, Stavros; Ulysse, Laura; Locarno, Andrea; Miseviciute, Ieva; De Felice, Alessia; Canella, Carola; Supekar, Kaustubh; Galbusera, Alberto; Menon, Vinod; Tonini, Raffaella; Deco, Gustavo; Lombardo, Michael V.; Pasqualetti, Massimo; Gozzi, Alessandro (Nature Research, 2021)

Postmortem studies have revealed increased density of excitatory synapses in the brains of individuals with autism spectrum disorder (ASD), with a putative link to aberrant mTORdependent synaptic pruning. ASD is also ...

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