• Preliminary evaluation of the safety and efficacy of glucose solution infusion through the hepatic artery on irreversible electroporation focusing

  Sarreshtehdari, Amirhossein; Burdío Pinilla, Fernando; López Alonso, Borja; Lucía, Óscar; Burdío, José M.; Villamonte, Maria; Andaluz, Anna; García Arnas, Félix; Berjano, Enrique J.; Moll, Xavier (Nature Research, 2023)

  Due to electrical features of the tissue, such as impedance, which have a significant impact on irreversible electroporation (IRE) function, the administration of glucose solution 5% (GS5%) through the hepatic artery would ...
• Association of occupational heat exposure and colorectal cancer in the MCC-Spain study

  Hinchliffe, Alice; Kogevinas, Manolis; Molina, Antonio J.; Moreno, Víctor; Aragonés, Núria; Castaño Vinyals, Gemma; Jiménez Moleón, José Juan; Gómez Acebo, Inés; Ederra, María; Amiano, Pilar; Molina-Barceló, Ana; Fernandez-Tardon, Guillermo; Alguacil Ojeda, Juan; Chirlaque, María Dolores; Hernández-Segura, Natalia; Pérez-Gómez, Beatriz; Pollan, Marina; Turner, Michelle C. (Nordic Association of Occupational Safety and Health (NOROSH), 2023)

  Objective: Heat exposure and heat stress/strain is a concern for many workers. There is increasing interest in potential chronic health effects of occupational heat exposure, including cancer risk. We examined potential ...
• Menstrual health and management during the COVID-19 syndemic in the Barcelona area (Spain): a qualitative study

  Holst, Anna Sofie; Jacques-Aviñó, Constanza; Berenguera, Anna; Martínez-Bueno, Cristina; Munrós-Feliu, Jordina; Pinzón-Sanabria, Diana; Valls Llobet, Carme; López-Jiménez, Tomàs; García-Egea, Andrea; Vicente-Hernández, Mª Mercedes; Medina Perucha, Laura (SAGE Publications, 2023)

  Background: Available evidence suggests that menstrual health and management have been impaired during the COVID-19 syndemic. However, research in this area is scarce, and it is failing to voice the experiences of women ...
• Quality of life with palbociclib plus fulvestrant versus placebo plus fulvestrant in postmenopausal women with endocrine-sensitive hormone receptor-positive and HER2-negative advanced breast cancer: patient-reported outcomes from the FLIPPER trial

  Tibau, Ariadna; Martínez, María Teresa; Ramos, Manuel; Cruz-Merino, Luis; Santaballa, Ana; O'Connor, Miriam; Martínez-Jáñez, Noelia; Moreno, Fernando; Fernández, Isaura; Virizuela, Juan Antonio; Alarcón, Jesús; Haba Rodríguez, Juan de la; Sánchez-Rovira, Pedro; Albacar, Cinta Rosa; Bueno Muiño, Carolia; Kelly, Catherine; Casas Sanahuja, Maribel; Bezares, Susana; Rosell, Libertad; Albanell Mestres, Joan (SAGE Publications, 2023)

  Background: In the FLIPPER trial, palbociclib/fulvestrant significantly improved progression-free survival (PFS) compared with placebo/fulvestrant in postmenopausal women with HR+/HER2- advanced breast cancer (ABC). ...
• Could an electronic tool to assess asthma control with a 1-day timeframe be useful for clinical management?

  Ferrer Forés, Maria Montserrat; Lizano-Barrantes, Catalina (Elsevier, 2023)
• The FAIR Cookbook - the essential resource for and by FAIR doers

  Rocca-Serra, Philippe; FAIR Cookbook Contributors; Sansone, Susanna-Assunta (Nature Research, 2023)

  The notion that data should be Findable, Accessible, Interoperable and Reusable, according to the FAIR Principles, has become a global norm for good data stewardship and a prerequisite for reproducibility. Nowadays, FAIR ...
• Considerations for an urban health perspective in Chile from the “Quiero Mi Barrio” program

  Olave-Müller, Paola; López Contreras, Natalia, 1986-; Alvarez Kocher, Patricio; Jirón, Paola; Bass Del Campo, Camilo; Burgos de la Vega, Soledad (Universidade de São Paulo, 2023)

  Objectives: To explore the perceptions of residents regarding their health and well-being in areas of personal and collective life, in relation to the experience of urban transformation originated by the Program for the ...
• Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart

  Milenkovic, Ivan; Santos Vieira, Helaine Graziele; Lucas, Morghan C.; Ruiz-Orera, Jorge; Patone, Giannino; Kesteven, Scott; Wu, Jianxin; Feneley, Michael; Espadas, Guadalupe; Sabidó Aguadé, Eduard, 1981-; Hübner, Norbert; van Heesch, Sebastiaan; Völkers, Mirko; Novoa, Eva Maria (Oxford University Press, 2023)

  The existence of naturally occurring ribosome heterogeneity is now a well-acknowledged phenomenon. However, whether this heterogeneity leads to functionally diverse 'specialized ribosomes' is still a controversial topic. ...
• Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming

  Generoso, Serena Francesca, 1988-; Neguembor, Maria Victoria; Hershberg, Elliot A.; Sadreyev, Ruslan Ilyasovich; Kurimoto, Kazuki; Yabuta, Yukihiro; Ricci, Raffaele; Audergon, Pauline; Bauer, Moritz, 1987-; Saitou, Mitinori; Hochedlinger, Konrad; Beliveau, Brian J.; Cosma, Maria Pia; Lee, Jeannie T.; Payer, Bernhard (National Academy of Sciences, 2023)

  Reactivation of the inactive X chromosome is a hallmark epigenetic event during reprogramming of mouse female somatic cells to induced pluripotent stem cells (iPSCs). This involves global structural remodeling from a ...
• Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease

  Alvarez Jerez, Pilar; Alcantud, Jose Luis; Reyes-Ramírez, Lucia de los; Moore, Anni; Ruz, Clara; Vives Montero, Francisco; Rodriguez-Losada, Noela; Saini, Prabhjyot; Gan-Or, Ziv; Alvarado, Chelsea X.; Makarious, Mary B.; Billingsley, Kimberley J.; Blauwendraat, Cornelis; Noyce, Alastair J.; Singleton, Andrew B.; Duran, Raquel; Bandres-Ciga, Sara (Nature Research, 2023)

  Neurodegeneration with brain iron accumulation (NBIA) represents a group of neurodegenerative disorders characterized by abnormal iron accumulation in the brain. In Parkinson's Disease (PD), iron accumulation is a cardinal ...
• Automated optimisation of solubility and conformational stability of antibodies and proteins

  Rosace, Angelo; Bennett, Anja; Oeller, Marc; Mortensen, Mie M.; Sakhnini, Laila; Lorenzen, Nikolai; Poulsen, Christian; Sormanni, Pietro (Nature Research, 2023)

  Biologics, such as antibodies and enzymes, are crucial in research, biotechnology, diagnostics, and therapeutics. Often, biologics with suitable functionality are discovered, but their development is impeded by developability ...
• Robustness and innovation in synthetic genotype networks

  Santos-Moreno, Javier; Tasiudi, Eve; Kusumawardhani, Hadiastri; Stelling, Joerg; Schaerli, Yolanda (Nature Research, 2023)

  Genotype networks are sets of genotypes connected by small mutational changes that share the same phenotype. They facilitate evolutionary innovation by enabling the exploration of different neighborhoods in genotype space. ...
• Natural green spaces, sensitization to allergens, and the role of gut microbiota during infancy

  Buchholz, Vienna; Bridgman, Sarah L.; Nielsen, Charlene C.; Gascon Merlos, Mireia, 1984-; Tun, Hein M.; Simons, Elinor; Turvey, Stuart E.; Subbarao, Padmaja; Takaro, Tim K.; Brook, Jeffrey R.; Scott, James A.; Mandhane, Piush J.; Kozyrskyj, Anita L. (American Society for Microbiology, 2023)

  The environment plays an instrumental role in the developmental origins of health and disease. Protective features of the environment in the development of asthma and atopy have been insufficiently studied. We used data ...
• Analyzing the role of cancer-associated fibroblast activation on macrophage polarization

  Bruch Oms, Marina; Olivera-Salguero, Rubén, 1991-; Mazzolini, Rocco; Valle Pérez, Beatriz del; Mayo González, Paula; Beteta, Ángel; Peña Arranz, Raúl; García de Herreros, Antonio (Wiley, 2023)

  Snail1 is a transcriptional factor required for cancer-associated fibroblast (CAF) activation, and mainly detected in CAFs in human tumors. In the mouse mammary tumor virus-polyoma middle tumor-antigen (MMTV-PyMT) model ...
• Copy number variation on ABCC2-DNMBP loci affects the diversity and composition of the fecal microbiota in pigs

  Ramayo-Caldas, Yuliaxis; Crespo-Piazuelo, Daniel; Morata, Jordi; González-Rodríguez, Olga; Sebastià, Cristina; Castelló, Anna; Dalmau, Antoni; Ramos-Onsins, Sebastián; Alexiou, Konstantinos G.; Folch, Josep M.; Quintanilla, Raquel; Ballester Devís, Maria (American Society for Microbiology, 2023)

  Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms (SNPs) and the gut ...
• Which outcomes should be measured in hand eczema trials? Results from patient interviews and an expert survey

  Rönsch, Henriette; Schiffers, Frederike; Ofenloch, Robert; Weisshaar, Elke; Buse, Anna-Sophie; Hansen, Andreas; John, Swen Malte; Giménez Arnau, Anna Maria; Pesqué, David; Agner, Tove; Nørreslet, Line Brok; Loman, Laura; Romeijn, Geertruida L. E.; Schuttelaar, Marie-Louise A.; Košćec Bjelajac, Adrijana; Macan, Jelena; Bauer, Andrea; Apfelbacher, Christian J. (Wiley, 2023)

  Background: Hand eczema (HE) is a common skin disease characterized by itch, pain and visible skin changes such as fissures, erythema and vesicles. It is not yet clear which outcome domains are most important for patients. ...
• First experience of wave speed guided point-by-point cavo-tricuspid isthmus ablation for typical atrial flutter

  Vallès, Ermengol; Jiménez, Jesús; González, Carlos; Zaraket, Fatima; Rodríguez, Oriol; Llorca, Laia; Anguera, Ignasi; di Marco, Andrea; Fan, Roger; Casteigt, Benjamin (Springer, 2023)
• Why a complete response is the treatment aim in chronic spontaneous urticaria

  Bernstein, Jonathan A.; Giménez Arnau, Anna Maria; Maurer, Marcus; Staubach, Petra; Barbier, Nathalie; Hua, Eva; Severin, Thomas; Laires, Pedro A.; Balp, Maria Magdalena (MDPI, 2023)

  This study investigated the association between urticaria activity and health-related quality of life (HRQoL). Patient evaluations from the ligelizumab Phase 2b clinical trial (N = 382) were pooled (NCT02477332). Daily ...
• Beauveria bassiana rewires molecular mechanisms related to growth and defense in tomato

  Proietti, Silvia; Falconieri, Gaia Salvatore; Bertini, Laura; Pascale, Alberto; Bizzarri, Elisabetta; Morales Sanfrutos, Julia; Sabidó Aguadé, Eduard, 1981-; Ruocco, Michelina; Monti, Maurilia M.; Russo, Assunta; Dziurka, Kinga; Ceci, Marcello; Loreto, Francesco; Caruso, Carla (Oxford University Press, 2023)

  Plant roots can exploit beneficial associations with soil-inhabiting microbes, promoting growth and expanding the immune capacity of the host plant. In this work, we aimed to provide new information on changes occurring ...
• Electronic Cigarette Use in 12 European countries: results from the TackSHS survey

  Gallus, Silvano; Lugo, Alessandra; Stival, Chiara; Cerrai, Sonia; Clancy, Luke; Filippidis, Filippos T.; Gorini, Giuseppe; López, Maria José; López Nicolás, Ángel; Molinaro, Sabrina; Odone, Anna; Soriano, Joan B.; Tigova, Olena; van den Brandt, Piet A.; Vardavas, Constantine; Fernández, Esteve; TackSHS Project Investigators (Japan Epidemiological Association, 2023)

  Background: Limited data on electronic cigarette prevalence, patterns, and settings of use are available from several European countries. Methods: Within the TackSHS project, a face-to-face survey was conducted in 2017-2018 ...

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