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Visualitza Recerca: articles, congressos, llibres per matèria "Exons"

Visualitza Recerca: articles, congressos, llibres per matèria "Exons"

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  • Castelo Valdueza, Robert; Reymond, Alexandre; Wyss, Carine; Cámara, Francisco; Parra Farré, Genís; Antonarakis, Stylianos E.; Guigó Serra, Roderic; Eyras Jiménez, Eduardo (Oxford University Press, 2005)
    The recent availability of the chicken genome sequence poses the question of whether there are human protein-coding genes conserved in chicken that are currently not included in the human gene catalog. Here, we show, using ...
  • Corvelo, André; Eyras Jiménez, Eduardo (BioMed Central, 2008)
    BACKGROUND: A large proportion of species-specific exons are alternatively spliced. In primates, Alu elements play a crucial role in the process of exon creation but many new exons have appeared through other mechanisms. ...
  • Tilgner, Hagen, 1980-; Guigó Serra, Roderic (Taylor & Francis (Routledge), 2010)
    RNA plays a central role in the determination of the phenotype of the cell. The molecular mechanisms involved in primary RNA synthesis and subsequent post-processing are not completely understood, but there is increasing ...
  • Eyras Jiménez, Eduardo; Reymond, Alexandre; Castelo Valdueza, Robert; Bye, Jacqueline M.; Cámara, Francisco; Flicek, Paul; Huckle, Elizabeth J.; Parra Farré, Genís; Shteynberg, David D.; Wyss, Carine; Rogers, Jane; Antonarakis, Stylianos E.; Birney, Ewan; Guigó Serra, Roderic; Brent, Michael R. (BioMed Central, 2005)
    Background: Despite the continuous production of genome sequence for a number of organisms,/nreliable, comprehensive, and cost effective gene prediction remains problematic. This is particularly/ntrue for genomes for which ...
  • Papasaikas, Panagiotis; Rao, Arvind; Huggins, Peter; Valcárcel, J. (Juan); López Aldea, Javier (BioMed Central, 2015)
    We present a computational framework tailored for the modeling of the complex, dynamic relationships that are encountered in splicing regulation. The starting point is whole-genome transcriptomic data from high-throughput ...
  • Llorian, Miriam; Gooding, Clare; Bellora Pereyra, Nicolás; Hallegger, Martina; Buckroyd, Adrian; Wang, Xiao; Rajgor, Dipen; Kayikci, Melis; Feltham, Jack; Ule, Jernej; Eyras Jiménez, Eduardo; Smith, Christopher, W. J. (Oxford University Press, 2016)
    Alternative splicing (AS) is a key component of gene expression programs that drive cellular differentiation. Smooth muscle cells (SMCs) are important in the function of a number of physiological systems; however, investigation ...
  • Julien, Philippe; Miñana Gómez, Belén; Baeza Centurion, Pablo; Valcárcel, J. (Juan); Lehner, Ben, 1978- (Nature Publishing Group, 2016)
    The properties of genotype-phenotype landscapes are crucial for understanding evolution but are not characterized for most traits. Here, we present a >95% complete local landscape for a defined molecular function-the ...