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Visualitza Recerca: articles, congressos, llibres per autor "Calafell i Majó, Francesc"

Visualitza Recerca: articles, congressos, llibres per autor "Calafell i Majó, Francesc"

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  • Sikora, Martin, 1976-; Laayouni, Hafid, 1968-; Calafell i Majó, Francesc; Comas, David, 1969-; Bertranpetit, Jaume, 1952- (Nature Publishing Group, 2011)
    Studies of large sets of SNP data have proven to be a powerful tool in the analysis of the genetic structure of human populations. In this work, we analyze genotyping data for 2,841 SNPs in 12 Sub-Saharan African populations, ...
  • Moreno Estrada, Andrés; Aparicio i Prat, Estel, 1986-; Sikora, Martin, 1976-; Engelken, Johannes; Ramírez Soriano, Anna; Calafell i Majó, Francesc; Bosch Fusté, Elena (BioMed Central, 2010)
    Background: The human FOXI1 gene codes for a transcription factor involved in the physiology of the inner ear, testis, and kidney. Using three interspecies comparisons, it has been suggested that this may be a gene ...
  • Garcia Etxebarria, Koldo; García Garcerà, Marc; Calafell i Majó, Francesc (BioMed Central, 2014)
    Background: Metagenomics is the genomic study of uncultured environmental samples, which has been greatly facilitated by the advent of shotgun-sequencing technologies. One of the main focuses of metagenomics is the discovery ...
  • Bosch Fusté, Elena; Laayouni, Hafid, 1968-; Morcillo Suárez, Carlos; Casals López, Ferran; Moreno Estrada, Andrés; Ferrer Admetlla, Anna; Gardner, Michelle; Rosa, Araceli; Comas, David, 1969-; Graffelman, Jan; Calafell i Majó, Francesc; Bertranpetit, Jaume, 1952- (BioMed Central, 2009)
    Background: It is well known that the pattern of linkage disequilibrium varies between human populations, with remarkable geographical stratification. Indirect association studies routinely exploit linkage disequilibrium ...
  • Dzunková, Mária; García Garcerà, Marc; Martínez Priego, Llúcia; D'Auria, Giussepe; Calafell i Majó, Francesc; Moya, Andrés (Public Library of Science (PLoS), 2014)
    The large amount of DNA needed to prepare a library in next generation sequencing protocols hinders direct sequencing of small DNA samples. This limitation is usually overcome by the enrichment of such samples with whole ...
  • García Garcerà, Marc; Gigli, Elena, 1978-; Sánchez Quinto, Federico A, 1985-; Ramírez, Oscar; Calafell i Majó, Francesc; Civit, Sergi; Lalueza Fox, Carles, 1965- (Public Library of Science (PLoS), 2011)
    Background: Despite the successful retrieval of genomes from past remains, the prospects for human palaeogenomics remain unclear because of the difficulty of distinguishing contaminant from endogenous DNA sequences. Previous ...
  • Casals López, Ferran; Sikora, Martin, 1976-; Laayouni, Hafid, 1968-; Montanucci, Ludovica, 1978-; Muntasell, Aura; Lazarus, Ross; Calafell i Majó, Francesc; Awadalla, Philip; Netea, Mihai G; Bertranpetit, Jaume, 1952- (BioMed Central, 2011)
    Background: Pathogens have represented an important selective force during the adaptation of modern human populations to changing social and other environmental conditions. The evolution of the immune system has therefore ...
  • Bekada, Asmahan; Arauna, Lara R; Deba, Tahria; Calafell i Majó, Francesc; Benhamamouch, Soraya; Comas, David, 1969- (Public Library of Science (PLoS), 2015)
    The demographic history of human populations in North Africa has been characterized by complex processes of admixture and isolation that have modeled its current gene pool. Diverse genetic ancestral components with different ...
  • Mendizábal Eceizabarrena, Isabel, 1981-; Sandoval Mendoza, Karla; Berniell Lee, Gemma; Calafell i Majó, Francesc; Salas, Antonio; Martínez Fuentes, Antonio; Comas, David, 1969- (BioMed Central, 2008)
    Background: Before the arrival of Europeans to Cuba, the island was inhabited by two Native American groups, the Tainos and the Ciboneys. Most of the present archaeological, linguistic and ancient DNA evidence indicates a ...
  • Kalaydjieva, Luba; Gresham, David; Calafell i Majó, Francesc (BioMed Central, 2001)
    Background: Data provided by the social sciences as well as genetic research suggest that the 8-10 million Roma (Gypsies) who live in Europe today are best described as a conglomerate of genetically isolated founder ...
  • González Neira, Anna; Calafell i Majó, Francesc; Navarro i Cuartiellas, Arcadi, 1969-; Lao Grueso, Oscar, 1976-; Cann, Howard M.; Comas, David, 1969-; Bertranpetit, Jaume, 1952- (BioMed Central, 2004)
    Recent studies of haplotype diversity in a number of genomic regions have suggested that long stretches of DNA are preserved in the same chromosome, with little evidence of recombination events. The knowledge of the extent ...
  • Moreno Estrada, Andrés; Bosch Fusté, Elena; Stoneking, Mark; Bertranpetit, Jaume, 1952-; Calafell i Majó, Francesc; Navarro i Cuartiellas, Arcadi, 1969-; Casals López, Ferran; Tang, Kun; Marquès i Bonet, Tomàs, 1975-; Sikora, Martin, 1976- (Oxford University Press, 2009)
    Different signatures of natural selection persist over varying time scales in our genome, revealing possible episodes of adaptative evolution during human history. Here, we identify genes showing signatures of ancestral ...
  • Casals López, Ferran; Anglada Busquets, Roger; Bonet, Núria; Rasal Soteras, Raquel; van der Gaag, Kristiaan J.; Hoogenboom, Jerry; Solé Morata, Neus; Comas, David, 1969-; Calafell i Majó, Francesc (Elsevier, 2017)
    We have genotyped the 58 STRs (27 autosomal, 24 Y-STRs and 7 X-STRs) and 94 autosomal SNPs in Illumina ForenSeq™ Primer Mix A in 88 Spanish Roma (Gypsy) samples and 143 Catalans. Since this platform is based in massive ...
  • Sandoval Mendoza, Karla; Buentello Malo, Leonor; Peñaloza Espinosa, Rosenda; Avelino, Heriberto; Salas, Antonio; Calafell i Majó, Francesc; Comas, David, 1969- (Springer, 2009)
    Mesoamerica, defined as the broad linguistic and cultural area from middle southern Mexico to Costa Rica, might have played a pivotal role during the colonization of the/nAmerican continent. It has been suggested that the ...
  • Spataro, Nino; Calafell i Majó, Francesc; Cervera, Laura; Casals, Ferran; Pagonabarraga, Javier; Pascual Sedano, Berta; Campolongo, Antònia; Kulisevsky, Jaime J.; Lleó, Alberto; Navarro i Cuartiellas, Arcadi, 1969-; Clarimón Echevarría, Jordi; Bosch Fusté, Elena (Oxford University Press, 2015)
    Parkinson's disease (PD) can be divided into familial (Mendelian) and sporadic forms. A number of causal genes have been discovered for the Mendelian form, which constitutes 10-20% of the total cases. Genome-wide association ...
  • Parida, Laxmi; Javed, Asif; Melé Messeguer, Marta, 1982-; Calafell i Majó, Francesc; Bertranpetit, Jaume, 1952-; Genographic Consortium (BioMed Central, 2009)
    Background: We address the problem of studying recombinational variations in (human) populations. In this paper, our focus is on one computational aspect of the general task: Given two networks G1 and G2, with both mutation ...
  • García Garcerà, Marc; Garcia Etxebarria, Koldo; Coscollà, Mireia; Latorre, Amparo; Calafell i Majó, Francesc (Public Library of Science (PLoS), 2013)
    In the last decade, an extensive effort has been made to characterize the human microbiota, due to its clinical and economic interests. However, a metagenomic approach to the skin microbiota is hampered by the high proportion ...
  • Melé Messeguer, Marta, 1982-; Javed, Asif; Pybus Oliveras, Marc, 1985-; Calafell i Majó, Francesc; Parida, Laxmi; Bertranpetit, Jaume, 1952-; The Genographic Consortium (Public Library of Science (PLoS), 2010)
    Recombination is one of the main forces shaping genome diversity, but the information it generates is often overlooked. A recombination event creates a junction between two parental sequences that may be transmitted to the ...
  • Garcia Etxebarria, Koldo; Bracho, María Alma; Galán, Juan Carlos; Pumarola, Tomás; Castilla, Jesús; Ortiz de Lejarazu, Raúl; Rodríguez Domínguez, Mario; Quintela Garcia, Ines; Bonet, Núria; García Garcerà, Marc; Domínguez, Ángela; González Candela, Fernando; Calafell i Majó, Francesc (Public Library of Science (PLoS), 2015)
    While most patients affected by the influenza A(H1N1) pandemic experienced mild symptoms, a small fraction required hospitalization, often without concomitant factors that could explain such a severe course. We hypothesize ...
  • Marigorta, Urko M.; Lao Grueso, Oscar, 1976-; Casals López, Ferran; Calafell i Majó, Francesc; Morcillo Suárez, Carlos; Faria, Rui; Bosch Fusté, Elena; Serra, François; Bertranpetit, Jaume, 1952-; Dopazo, Hernán; Navarro i Cuartiellas, Arcadi, 1969- (BioMed Central, 2011)
    Background: Searching for associations between genetic variants and complex diseases has been a very active area of research for over two decades. More than 51,000 potential associations have been studied and published, a ...