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Browsing Recerca: articles, congressos, llibres by Subject "T cells"

Browsing Recerca: articles, congressos, llibres by Subject "T cells"

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  • Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity
    Martínez Pasamar, Sara; Abad Adan, Elena; Moreno, Beatriz; Vélez de Mendizábal, Nieves; Martínez Forero, Ivan; García Ojalvo, Jordi; Villoslada, Pablo (BioMed Central, 2013)
    Background: Multiple Sclerosis (MS) is considered a T-cell-mediated autoimmune disease with a prototypical oscillatory behavior, as evidenced by the presence of clinical relapses. Understanding the dynamics of immune cells ...
  • Epstein-Barr virus+ B cells in breast cancer immune response: a case report
    Aran, Andrea; Peg, Vicente; Rabanal, Rosa María; Bernadó, Cristina; Zamora, Esther; Molina, Elisa; Arribas, Yago A.; Arribas, Joaquín; Pérez, José; Roura-Mir, Carme; Carrascal, Montserrat; Cortés, Javier; Martí, Mercè (Frontiers, 2021)
    EBV-specific T cells have been recently described to be involved in fatal encephalitis and myocarditis in cancer patients after immune checkpoint therapies. Here, we report the study of a human triple-negative breast cancer ...
  • Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types
    Ecker, Simone; Merkel, Angelika; BLUEPRINT Consortium; Paul, Dirk S. (BioMed Central, 2017)
    Background: A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability. Results: We apply a novel ...
  • Lymphocyte Activation Dynamics Is Shaped by Hereditary Components at Chromosome Region 17q12-q21
    Carreras Sureda, Amado, 1986-; Rubio Moscardó, Fanny; Olvera, Alex; Argilaguet Marqués, Jordi, 1977-; Kiefer, Kerstin, 1986-; Mothe, Beatriz; Meyerhans, Andreas; Brander, Christian; Vicente García, Rubén, 1978- (Public Library of Science (PLoS), 2016)
    Single nucleotide polymorphisms (SNPs) located in the chromosome region 17q12-q21 are risk factors for asthma. Particularly, there are cis-regulatory haplotypes within this region that regulate differentially the expression ...
  • Prediction of PD-L1 inhibition effects for HIV-infected individuals
    Zheltkova, Valerya; Argilaguet Marqués, Jordi, 1977-; Peligero Cruz, Cristina, 1986-; Bocharov, Gennady A.; Meyerhans, Andreas (Public Library of Science (PLoS), 2019)
    The novel therapies with immune checkpoint inhibitors hold great promises for patients with chronic virus infections and cancers. This is based mainly on the partial reversal of the exhausted phenotype of antigen-specific ...
  • Spatiotemporal Dynamics of Virus Infection Spreading in Tissues
    Bocharov, Gennady A.; Meyerhans, Andreas; Bessonov, Nickolay; Trofimchuk, Sergei; Volpert, Vitaly (Public Library of Science (PLoS), 2016)
    Virus spreading in tissues is determined by virus transport, virus multiplication in host cells and the virus-induced immune response. Cytotoxic T cells remove infected cells with a rate determined by the infection level. ...
  • The expression of IL-17, in chronic spontaneous urticaria is linked to Semaphorin5A
    Matanis, Lobna; Eiza, Nasren; Sabag, Adi; Bejar, Jacob; Giménez Arnau, Anna Maria; Maurer, Marcus; Vadasz, Zahava (MDPI, 2021)
    Background: Patients with chronic spontaneous urticaria (CSU), an autoimmune disorder, show increased skin expression of IL-17A and can benefit from treatment with the anti-IL-17A biologic secukinumab. The mechanisms that ...
  • Understanding allergic multimorbidity within the non-eosinophilic interactome
    Aguilar, Daniel; Lemonnier, Nathanael; Koppelman, Gerard H.; Melén, Erik; Oliva Miguel, Baldomero; Pinart, Mariona; Guerra, Stefano; Bousquet, Jean; Antó i Boqué, Josep Maria (Public Library of Science (PLoS), 2019)
    Background: The mechanisms explaining multimorbidity between asthma, dermatitis and rhinitis (allergic multimorbidity) are not well known. We investigated these mechanisms and their specificity in distinct cell types by ...

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