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Browsing Recerca: articles, congressos, llibres by Subject "Saccharomyces cerevisiae -- Metabolisme"

Browsing Recerca: articles, congressos, llibres by Subject "Saccharomyces cerevisiae -- Metabolisme"

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  • Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Public Library of Science (PLoS), 2015)
    Whole-genome duplications have shaped the genomes of several vertebrate, plant, and fungal lineages. Earlier studies have focused on establishing when these events occurred and on elucidating their functional and evolutionary ...
  • Schaber, Jörg; Adrover Nadal, Miguel Angel; Eriksson, Emma; Pelet, Serge; Petelenz-Kurdziel, Elzbieta; Klein, Dagmara; Posas Garriga, Francesc; Goksör, Mattias; Peter, Matthias; Hohmann, Stefan; Klipp, E., 1965- (Springer Verlag, 2010)
    Parameterized models of biophysical and mechanical cell properties are important for predictive mathematical modeling of cellular processes. The concepts of turgor, cell wall elasticity, osmotically active volume, and ...
  • Gabrielli, Natalia, 1978-; Ayté del Olmo, José; Hidalgo Hernando, Elena (American Society for Biochemistry and Molecular Biology (ASBMB), 2012)
    Friedreich ataxia is a genetic disease caused by deficiencies in frataxin. This protein has homologs not only in higher eukaryotes but also in bacteria, fungi, and plants. The function of this protein is still controversial. ...
  • Opulente, Dana A.; Morales, Christopher M.; Carey, Lucas; Rest, Joshua S. (Public Library of Science (PLoS), 2013)
    Phenotypic traits may be gained and lost together because of pleiotropy, the involvement of common genes and networks, or because of simultaneous selection for multiple traits across environments (multiple-trait coevolution). ...
  • Nadal Ribelles, Mariona, 1984-; Solé, Carme; Xu, Zhenyu; Steinmetz, Lars M.; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Elsevier, 2014)
    Genomic analysis has revealed the existence of a large number of long noncoding RNAs (lncRNAs) with different functions in a variety of organisms, including yeast. Cells display dramatic changes of gene expression upon ...
  • Solé, Carme; Nadal Ribelles, Mariona, 1984-; Kraft, Claudine; Peter, Matthias; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Nature Publishing Group, 2011)
    Protein ubiquitylation is a key process in the regulation of many cellular processes. The balance between the activity of ubiquitin ligases and that of proteases controls the level of ubiquitylation. In response to ...
  • Duch, Alba; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Elsevier, 2013)
    Transcription during S phase needs to be spatially and temporally regulated to prevent collisions between the transcription and replication machineries. Cells have evolved a number of mechanisms to make both processes ...
  • Nadal Ribelles, Mariona, 1984-; Mas Martín, Glòria; Millán Zambrano, Gonzalo; Solé, Carme; Ammerer, Gustav; Chávez, Sebastián; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Oxford University Press, 2015)
    Chromatin remodeling is essential for proper adaptation to extracellular stimuli. The p38-related Hog1 SAPK is an important regulator of transcription that mediates chromatin remodeling upon stress. Hog1 targets the RSC ...
  • Galão, Rui Pedro Ribeiro; Chari, Ashwin; Alves-Rodrigues, Isabel; Lobão, Daniela; Mas, Antonio; Kambach, Christian; Fischer, Utz; Díez Antón, Juana, 1962- (Cold Spring Harbor Laboratory Press (CSHL Press), 2010)
    LSm1-7 complexes promote cellular mRNA degradation, in addition to translation and replication of positive-strand RNA viruses such as the Brome mosaic virus (BMV). Yet, how LSm1-7 complexes act on their targets remains ...
  • Carey, Lucas; Shalem, Ophir; Zeevi, Danny; Sharon, Elion; Keren, Leeat; Weinberger, Adina; Dahan, Orna; Pilpel, Yitzhak; Segal, Eran (Public Library of Science (PLoS), 2013)
    A full understanding of gene regulation requires an understanding of the contributions that the various regulatory regions have on gene expression. Although it is well established that sequences downstream of the main ...
  • Rest, Joshua S.; Morales, Christopher M.; Waldron, John B.; Opulente, Dana A.; Fisher, Julius; Moon, Seungjae; Bullaughey, Kevin; Carey, Lucas; Dedousis, Demitri (University of Chicago Press, 2013)
    Levels of gene expression show considerable variation in eukaryotes, but no fine-scale maps have been made of the fitness consequences of such variation in controlled genetic backgrounds and environments. To address this, ...
  • Sharifian, Hoda; Lampert, Fabienne; Stojanovski, Klement; Regot Rodríguez de Mier, Sergi; Vaga, Stefania; Buser, Raymond; Lee, Sung Sik; Koeppl, Heinz; Posas Garriga, Francesc; Pelet, Serge; Peter, Matthias (Royal Society of Chemistry, 2015)
    Tight regulation of the MAP kinase Hog1 is crucial for survival under changing osmotic conditions. Interestingly, we found that Hog1 phosphorylates multiple upstream components, implying feedback regulation within the ...
  • Carey, Lucas; Dijk, David van; Sloot, Peter MA; Kaandorp, Jaap A; Segal, Eran (Public Library of Science (PLoS), 2013)
    The ability of cells to accurately control gene expression levels in response to extracellular cues is limited by the inherently stochastic nature of transcriptional regulation. A change in transcription factor (TF) activity ...
  • Al-Shahrour, Fátima; Minguez, Pablo; Marquès i Bonet, Tomàs, 1975-; Gazave, Elodie; Navarro i Cuartiellas, Arcadi, 1969-; Dopazo, Joaquín (Public Library of Science (PLoS), 2010)
    An increasing number of evidences show that genes are not distributed randomly across eukaryotic chromosomes, but rather in functional neighborhoods. Nevertheless, the driving force that originated and maintains such ...
  • Vendrell Arasa, Alexandre; Martínez Pastor, Mar; González Novo, Alberto; Pascual Ahuir, Amparo; Sinclair, David A.; Proft, Markus; Posas Garriga, Francesc (Nature Publishing Group, 2011)
    Exposure of yeast to high osmolarity induces a transient activation of the Hog1 stress-activated protein kinase (SAPK), which is required for cell survival under these conditions. However, sustained activation of the SAPK ...
  • Ruiz Roig, Clàudia; Noriega Esteban, Núria; Duch, Alba; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (American Society for Cell Biology, 2012)
    Cells modulate expression of nuclear genes in response to alterations in mitochondrial function, a response termed retrograde (RTG) regulation. In budding yeast, the RTG pathway relies on Rtg1 and Rtg3 basic helix-loop-helix ...
  • Jungfleisch, Jennifer, 1986-; Chowdhury, Ashis; Alves-Rodrigues, Isabel; Tharun, Sundaresan; Díez Antón, Juana, 1962- (Cold Spring Harbor Laboratory Press, 2015)
    The Lsm1-7-Pat1 complex binds to the 3' end of cellular mRNAs and promotes 3' end protection and 5'-3' decay. Interestingly, this complex also specifically binds to cis-acting regulatory sequences of viral positive-strand ...
  • Boronat i Llop, Susanna, 1965-; Domènech, Alba; Paulo Mirasol, Esther, 1984-; Calvo, Isabel A.; García Santamarina, Sarela, 1978-; García, Patrícia; Encinar del Dedo, Javier; Barcons, Anna; Serrano, Erica; Carmona, Mercè; Hidalgo Hernando, Elena (Elsevier, 2014)
    Cysteine residues, and in particular their thiolate groups, react not only with reactive oxygen species but also with electrophiles and with reactive nitrogen species. Thus, cysteine oxidation has often been linked to the ...
  • Giménez-Barcons, Mireia; Díez Antón, Juana, 1962- (BioMed Central, 2011)
    Processing bodies (PBs) and stress granules (SGs) are two highly conserved cytoplasmic ribonucleoprotein foci that contain translationally repressed mRNAs together with proteins from the mRNA metabolism. Interestingly, ...

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