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A chemocentric approach to the identification of cancer targets

Flachner, Beáta; Lorincz, Zsolt; Carotti, Angelo; Nicolotti, Orazio; Kuchipudi, Praveena; Kuchipudi, Praveena; Remez Vinogradov, Nikita, 1985-; Sanz, Ferran; Tóvári, József; Szabo, Miklós J; Bertók, Béla; Cseh, Sándor; Mestres i López, Jordi; Dormán, György (Public Library of Science (PLoS), 2012)

A novel chemocentric approach to identifying cancer-relevant targets is introduced. Starting with a large chemical collection, the strategy uses the list of small molecule hits arising from a differential cytotoxicity ...