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Beneficial effects of olive oil and Mediterranean diet on cancer physio-pathology and incidence

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dc.contributor.author Farràs Mañé, Marta
dc.contributor.author Almanza-Aguilera, Enrique
dc.contributor.author Hernáez, Álvaro
dc.contributor.author Agustí, Núria
dc.contributor.author Julve, Josep
dc.contributor.author Fitó Colomer, Montserrat
dc.contributor.author Castañer, Olga
dc.date.accessioned 2022-02-17T07:52:26Z
dc.date.issued 2021
dc.identifier.citation Farràs M, Almanza-Aguilera E, Hernáez Á, Agustí N, Julve J, Fitó M, et al. Beneficial effects of olive oil and Mediterranean diet on cancer physio-pathology and incidence. Semin Cancer Biol. 2021 Aug; 73: 178-95. DOI: 10.1016/j.semcancer.2020.11.011
dc.identifier.issn 1044-579X
dc.identifier.uri http://hdl.handle.net/10230/52513
dc.description.abstract Virgin olive oil is a characteristic component and the main source of fat of the Mediterranean diet. It is a mix of high-value health compounds, including monounsaturated fatty acids (mainly oleic acid), simple phenols (such as hydroxytyrosol and tyrosol), secoiridoids (such as oleuropein, oleocanthal), flavonoids, and terpenoids (such as squalene). Olive oil consumption has been shown to improve different aspects of human health and has been associated with a lower risk of cancer. However, the underlying cellular mechanisms involved in such effects are still poorly defined, but seem to be related to a promotion of apoptosis, modulation of epigenetic patterns, blockade of cell cycle, and angiogenesis regulation. The aim of this review is to update the current associations of cancer risk with the Mediterranean diet, olive oil consumption and its main components. In addition, the identification of key olive oil components involved in anticarcinogenic mechanisms and pathways according to experimental models is also addressed.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Elsevier
dc.rights © Elsevier http://dx.doi.org/10.1016/j.semcancer.2020.11.011
dc.title Beneficial effects of olive oil and Mediterranean diet on cancer physio-pathology and incidence
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1016/j.semcancer.2020.11.011
dc.subject.keyword Cancer
dc.subject.keyword Fatty acids
dc.subject.keyword Mediterranean diet
dc.subject.keyword Olive oil
dc.subject.keyword Phenolic compounds
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion

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