• C/EBPα instructs trophectoderm and pluripotency through the II6 pathway

  Plana Carmona, Marcos, 1993- (2021-04-09)

  Continuous C/EBPa expression converts B cells into macrophages while its transient upregulation before the Yamanaka factors yields highly efficient iPSC reprogramming. C/EBP members regulate Il6 pathway genes and IL-6 ...
• The Role of the LRRC8A anion channel in adaptation to stress

  Stojakovic, Predrag (Universitat Pompeu Fabra, 2023-03-10)

  Cell volume regulation is essential for cellular homeostasis and adaptation to environmental osmotic changes. Upon hyperosmotic stress, cells need to rapidly restore osmotic balances in order to preserve the function of ...
• Decoding the immune evasive properties of cancer stem cells in breast cancer immunotherapy resistance

  Pérez Núñez, Iván (Universitat Pompeu Fabra, 2023-03-17)

  Cancer stem cells (CSCs) fuels tumours and are involved in therapy resistance, yet their contribution immunotherapy resistance and immunological properties are poorly understood. Herein, we show that within tumour phenotypic ...
• Charting the heterogeneity of healthy and malignant immune cells, one cell at a time

  Massoni Badosa, Ramon (Universitat Pompeu Fabra, 2023-03-17)

  Specialization and plasticity are hallmarks of immune cells. Thus, charting their heterogeneity is crucial to understand their function and role in diseases. In this setting, single-cell RNA-sequencing (scRNA-seq) has ...
• Genetic associations on major depression: curation and functional analysis

  Pérez Granado, Judith (Universitat Pompeu Fabra, 2023-03-10)

  Major depression (MD) is the leading cause of impairment worldwide. The lack of understanding of its biological underpinnings hampers the development of better diagnostic tools and treatments. Thanks to the advances in ...
• Greener on the other side?: greenspace exposure and cardiovascular health

  Bauwelinck, Mariska Georgette M. (Universitat Pompeu Fabra, 2023-03-17)

  The last century has been marked by perhaps the greatest demographic transition in human history. The processes related thereto, such as rapid urbanization and population ageing, pose a major public health concern, and ...
• Generation and validation of a CRISPR platform for rapid and inducible genome editing in human pluripotent stem cells and kidney organoids

  Marco Giménez, Andrés, 1993- (2022-03-16)

  Our current knowledge about the function of human genes is mostly based on data from genetic studies using animal models. However, divergence among species may hamper the understanding of genetic mechanisms underlying human ...
• Avaluació i maneig de la lesió diafragmàtica associada a la ventitació mecànica en el pacient crític

  Dot Jordana, Irene, 1982- (2022-03-16)

  La lesió diafragmàtica associada a la ventilació́ mecànica (VIDD) és prevalent, infraestimada i amb implicacions pronòstiques. El seu estudi és complex i el seu diagnòstic, difícil. Aquesta Tesi inclou dos articles amb ...
• Análisis de contenidos y resultados diagnósticos en la evaluación del trastorno depresivo mayor

  Vilar Garcés, Ana (Universitat Pompeu Fabra, 2023-03-14)

  Introducción: El Trastorno Depresivo Mayor (TDM) es una enfermedad común que limita severamente el funcionamiento psicosocial y disminuye la calidad de vida. Clínicamente, el diagnóstico pasa por la entrevista clínica ...
• Essays on international trade and economic geography

  Yeşilbayraktar, Uğur (Universitat Pompeu Fabra, 2023-03-13)

  This thesis explores how international trade shapes economic geography and analyses the effects of borders and other trade costs on the pattern of trade. In the first chapter, I study how the reduction in trade costs ...
• K-fiber dynamics: a focus on the microtubule minus-ends

  Laguillo Diego, Alejandra, 1991- (2021-03-26)

  During cell division, microtubules (MTs) organize into a bipolar spindle that drives faithful chromosome segregation through the kinetochore fibers (k-fibers), bundles of parallel MTs that attach the chromosomes through ...
• Filmar las palabras

  Pena Morado, Alex (Universitat Pompeu Fabra, 2023-02-27)

  El presente trabajo de investigación se propone analizar los modos en que el cine ha llevado a cabo el acto de filmar los textos literarios. En oposición a la tendencia convencional en los estudios filmoliterarios que ...
• A Genome-wide CRISPR screen to identify novel pathways involved in reprogramming and x-chromosome reactivation

  Barrero Asencio, Mercedes (Universitat Pompeu Fabra, 2023-03-07)

  During reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), the epigenome needs to be reset. A prime example of this is the reversal of the silent state of the inactive X chromosome in female cells, ...
• Occupational heat exposure and cancer risk

  Hinchliffe, Alice (Universitat Pompeu Fabra, 2023-03-07)

  Heat exposure is a growing concern for many workers around the world as climate change is causing global average temperatures to rise. Heat exposure has been linked to a number of key carcinogenic processes, but current ...
• International juridical double taxation and individuals' ability to pay in the light of EU law

  Ildefonso Mendonça, Maria Júlia (Universitat Pompeu Fabra, 2023-03-08)

  According to the CJEU’s case law, the tax disadvantage suffered by taxpayers in a cross-border situation arising from international juridical double taxation does not constitute a forbidden obstacle to free movement because ...
• La vigilancia epidemiológica desde una aproximación sindémica: la vigilancia de las infecciones de transmisión sexual y de la tuberculosis centrada en poblaciones a riesgo de infección

  Sentís Fuster, Alexis (Universitat Pompeu Fabra, 2023-02-24)

  El propósito principal de la tesis es contribuir en lo posible a potenciar la vigilancia de las pandemias de las infecciones de transmisión sexual (ITS) y la tuberculosis (TB) en las poblaciones a riesgo de infección a ...
• Deep spatio-temporal neural network for facial analysis

  Aspandi Latif, Decky (Universitat Pompeu Fabra, 2021-03-24)

  Automatic Facial Analysis is one of the most important field of computer vision due to its significant impacts to the world we currently live in. Among many applications of Automatic Facial Analysis, Facial Alignment and ...
• La aplicación de competencias de subtitulación en asignaturas de traducción no audiovisuales de los estudios de grado en Traducción e Interpretación

  González Cruz, Sonia (Universitat Pompeu Fabra, 2021-02-09)

  Esta tesis se enmarca en el campo de la formación de traductores y se centra en el empleo de la subtitulación interlingüística activa como una herramienta didáctica en asignaturas de traducción del grado en Traducción e ...
• Accesibilidad y usos positivos aplicados de la realidad extendida (virtual, aumentada y mixta) para personas con movilidad reducida: hacia un Metaverso inclusivo

  Cañellas-Mayor, Alicia (Universitat Pompeu Fabra, 2023-02-27)

  Las tecnologías de la Realidad Extendida (XR) presentan retos de accesibilidad para las personas con movilidad reducida (PCMR), aunque también oportunidades que pueden beneficiar su bienestar. Para abordar ambos aspectos, ...
• La Forma-ritual del cine de Chantal Akerman: hacia un espectador encarnado

  Moreno Pellejero, Ariadna (Universitat Pompeu Fabra, 2023-02-27)

  Esta investigación nace de la necesidad de repensar los aportes estéticos del cine de Chantal Akerman, a los cuales me aproximo tratando de dar una posible respuesta a la pregunta, ¿en qué forma el cine de Akerman llega ...

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