In response to fluctuations in the environment, all living organisms have the ability to sense, respond and adapt to the new conditions. In budding yeast (Saccharomyces cerevisiae) there is a massive and rapid reorganization ...
In the field of teaching English literature to Spanish adolescents, a multimodal approach offers diverse modes of representation and brings potential for meaning making. However, teaching with digital technology or using ...
Tras el comienzo de la guerra civil en 1936 Juan Ramón Jiménez abandona España dejando en Madrid todos sus archivos y su biblioteca personal. Para esa fecha su formación intelectual y estética, iniciada a finales del s. ...
Con base en la distinción entre injusto culpable (suceso histórico) y hecho punible (concepto dinámico), el trabajo propone un modelo teórico para la identificación, clasificación y análisis de determinados comportamientos ...
Appropriate regulation of gene expression is necessary for correct development and homeostasis of organisms. Epigenetic mechanisms represent an additional layer of information, besides the genetic sequence, crucial for the ...
De Santiago , Jessica(Universitat Pompeu Fabra, 2021-04-07)
In neuropsychiatry, the development of brain imaging and dedicated data analysis for personalized medicine promises to predict both the evolution of diseases and responses of treatments. The ability to estimate the time ...
Esta investigación nace de la necesidad de repensar los aportes estéticos del cine de Chantal Akerman, a los cuales me aproximo tratando de dar una posible respuesta a la pregunta, ¿en qué forma el cine de Akerman llega ...
Cuando una obra literaria es trasladada a la gran pantalla y tanto la película resultante como la propia obra literaria se traducen a otro idioma, se crea entre el sistema emisor y el receptor un nexo de intercambio cultural ...
Continuous C/EBPa expression converts B cells into
macrophages while its transient upregulation before the
Yamanaka factors yields highly efficient iPSC
reprogramming. C/EBP members regulate Il6 pathway
genes and IL-6 ...
Cell volume regulation is essential for cellular homeostasis and adaptation to environmental osmotic changes. Upon hyperosmotic stress, cells need to rapidly restore osmotic balances in order to preserve the function of ...
Cancer stem cells (CSCs) fuels tumours and are involved in therapy resistance, yet their contribution immunotherapy resistance and immunological properties are poorly understood. Herein, we show that within tumour phenotypic ...
Specialization and plasticity are hallmarks of immune cells. Thus, charting their heterogeneity is crucial to understand their function and role in diseases. In this setting, single-cell RNA-sequencing (scRNA-seq) has ...
Major depression (MD) is the leading cause of impairment worldwide. The lack of understanding of its biological underpinnings hampers the development of better diagnostic tools and treatments. Thanks to the advances in ...
The last century has been marked by perhaps the greatest demographic transition in human history. The processes related thereto, such as rapid urbanization and population ageing, pose a major public health concern, and ...
Our current knowledge about the function of human genes is mostly based on data
from genetic studies using animal models. However, divergence among species may
hamper the understanding of genetic mechanisms underlying human ...
La lesió diafragmàtica associada a la ventilació́ mecànica (VIDD) és prevalent,
infraestimada i amb implicacions pronòstiques. El seu estudi és complex i el seu
diagnòstic, difícil. Aquesta Tesi inclou dos articles amb ...
Introducción: El Trastorno Depresivo Mayor (TDM) es una enfermedad común que limita severamente el funcionamiento psicosocial y disminuye la calidad de vida. Clínicamente, el diagnóstico pasa por la entrevista clínica ...
This thesis explores how international trade shapes economic geography and
analyses the effects of borders and other trade costs on the pattern of trade.
In the first chapter, I study how the reduction in trade costs ...
During cell division, microtubules (MTs) organize into a bipolar spindle that drives faithful chromosome segregation through the kinetochore fibers (k-fibers), bundles of parallel MTs that attach the chromosomes through ...
El presente trabajo de investigación se propone analizar los modos en que el cine ha llevado a cabo el acto de filmar los textos literarios. En oposición a la tendencia convencional en los estudios filmoliterarios que ...