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Clinical characterization of patients with COVID-19 in primary care in Catalonia: retrospective observational study

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dc.contributor.author Mayer, Miguel Ángel, 1960-
dc.contributor.author Vidal Alaball, Josep
dc.contributor.author Puigdellívol Sánchez, Anna
dc.contributor.author Marín Gómez, Francesc X.
dc.contributor.author Leis Machín, Angela 1974-
dc.contributor.author Mendioroz Peña, Jacobo
dc.date.accessioned 2021-06-22T06:52:38Z
dc.date.available 2021-06-22T06:52:38Z
dc.date.issued 2021
dc.identifier.citation Mayer MA, Vidal-Alaball J, Puigdellívol-Sánchez A, Marín Gomez FX, Leis A, Mendioroz Peña J. Clinical characterization of patients with COVID-19 in primary care in Catalonia: retrospective observational study. JMIR Public Health Surveill. 2021;7(2):e25452. DOI: 10.2196/25452
dc.identifier.issn 2369-2960
dc.identifier.uri http://hdl.handle.net/10230/47959
dc.description.abstract Background: The country of Spain has one of the highest incidences of COVID-19, with more than 1,000,000 cases as of the end of October 2020. Patients with a history of chronic conditions, obesity, and cancer are at greater risk from COVID-19; moreover, concerns surrounding the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin type II receptor blockers (ARBs) and its relationship to COVID-19 susceptibility have increased since the beginning of the pandemic. Objective: The objectives of this study were to compare the characteristics of patients diagnosed with COVID-19 to those of patients without COVID-19 in primary care; to determine the risk factors associated with the outcome of mortality; and to determine the potential influence of certain medications, such as ACEIs and ARBs, on the mortality of patients with COVID-19. Methods: An observational retrospective study of patients diagnosed with COVID-19 in the Catalan Central Region of Spain between March 1 and August 17, 2020, was conducted. The data were obtained from the Primary Care Services Information Technologies System of the Catalan Institute of Health in Barcelona, Spain. Results: The study population included 348,596 patients (aged >15 years) registered in the Primary Care Services Information Technologies System of the Catalan Central Region. The mean age of the patients was 49.53 years (SD 19.42), and 31.17% of the patients were aged ≥60 years. 175,484/348,596 patients (50.34%) were women. A total of 23,844/348,596 patients (6.84%) in the population studied were diagnosed with COVID-19 during the study period, and the most common clinical conditions of these patients were hypertension (5267 patients, 22.1%) and obesity (5181 patients, 21.7%). Overall, 2680/348,596 patients in the study population (0.77%) died during the study period. The number of deaths among patients without COVID-19 was 1825/324,752 (0.56%; mean age 80.6 years, SD 13.3), while among patients diagnosed with COVID-19, the number of deaths was 855/23,844 (3.58%; mean age 83.0 years, SD 10.80) with an OR of 6.58 (95% CI 6.06-7.15). Conclusions: We observed that women were more likely to contract COVID-19 than men. In addition, our study did not show that hypertension, obesity, or being treated with ACEIs or ARBs was linked to an increase in mortality in patients with COVID-19. Age is the main factor associated with mortality in patients infected with SARS-CoV-2.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher JMIR Publications
dc.relation.ispartof JMIR Public Health and Surveillance. 2021;7(2):e25452
dc.rights © Miguel Angel Mayer, Josep Vidal-Alaball, Anna Puigdellívol-Sánchez, Francesc X Marín Gomez, Angela Leis, Jacobo Mendioroz Peña. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 08.02.2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on http://publichealth.jmir.org, as well as this copyright and license information must be included.
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.title Clinical characterization of patients with COVID-19 in primary care in Catalonia: retrospective observational study
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.2196/25452
dc.subject.keyword COVID-19
dc.subject.keyword Spain
dc.subject.keyword Angiotensin II type 2 receptor blockers
dc.subject.keyword Angiotensin-converting enzyme inhibitors
dc.subject.keyword Characteristic
dc.subject.keyword Mortality
dc.subject.keyword Observational
dc.subject.keyword Primary health care
dc.subject.keyword Retrospective
dc.subject.keyword Risk
dc.subject.keyword Risk factors
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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