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Enriched music-supported therapy for chronic stroke patients: a study protocol of a randomised controlled trial

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dc.contributor.author Grau-Sánchez, Jennifer
dc.contributor.author Segura, Emma
dc.contributor.author Sanchez-Pinsach, David
dc.contributor.author Raghavan, Preeti
dc.contributor.author Münte, Thomas F.
dc.contributor.author Palumbo, Anna Marie
dc.contributor.author Turry, Alan
dc.contributor.author Duarte Oller, Esther
dc.contributor.author Särkämö, Teppo
dc.contributor.author Cerquides, Jesus
dc.contributor.author Arcos, Josep Lluís
dc.contributor.author Rodríguez-Fornells, Antoni
dc.date.accessioned 2021-05-28T07:47:43Z
dc.date.available 2021-05-28T07:47:43Z
dc.date.issued 2021
dc.identifier.citation Grau-Sánchez J, Segura E, Sanchez-Pinsach D, Raghavan P, Münte TF, Palumbo AM, et al. Enriched music-supported therapy for chronic stroke patients: a study protocol of a randomised controlled trial. BMC Neurol. 2021 Jan 12; 21(1): 19. DOI: 10.1186/s12883-020-02019-1
dc.identifier.issn 1471-2377
dc.identifier.uri http://hdl.handle.net/10230/47680
dc.description.abstract Background: Residual motor deficits of the upper limb in patients with chronic stroke are common and have a negative impact on autonomy, participation and quality of life. Music-Supported Therapy (MST) is an effective intervention to enhance motor and cognitive function, emotional well-being and quality of life in chronic stroke patients. We have adapted the original MST training protocol to a home-based intervention, which incorporates increased training intensity and variability, group sessions, and optimisation of learning to promote autonomy and motivation. Methods: A randomised controlled trial will be conducted to test the effectiveness of this enriched MST (eMST) protocol in improving motor functions, cognition, emotional well-being and quality of life of chronic stroke patients when compared to a program of home-based exercises utilizing the Graded Repetitive Arm Supplementary Program (GRASP). Sixty stroke patients will be recruited and randomly allocated to an eMST group (n = 30) or a control GRASP intervention group (n = 30). Patients will be evaluated before and after a 10-week intervention, as well as at 3-month follow-up. The primary outcome of the study is the functionality of the paretic upper limb measured with the Action Research Arm Test. Secondary outcomes include other motor and cognitive functions, emotional well-being and quality of life measures as well as self-regulation and self-efficacy outcomes. Discussion: We hypothesize that patients treated with eMST will show larger improvements in their motor and cognitive functions, emotional well-being and quality of life than patients treated with a home-based GRASP intervention. Trial registration: The trial has been registered at ClinicalTrials.gov and identified as NCT04507542 on 8 August 2020.
dc.description.sponsorship This work was supported by the Ministerio de Ciencia, Innovación y Universidades (ref. PGC2018-099859-B-I00) to A.R.F, by 2017-SGR-172 from Generalitat de Catalunya to J.L.A. Study resulting from the 201729.30 project, funded by La Marató de TV3. We thank CERCA Programme / Generalitat de Catalunya for institutional support.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher BioMed Central
dc.rights Copyright © The Author(s) 2021. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies t
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.title Enriched music-supported therapy for chronic stroke patients: a study protocol of a randomised controlled trial
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1186/s12883-020-02019-1
dc.subject.keyword Music therapy
dc.subject.keyword Music-supported therapy
dc.subject.keyword Rehabilitation
dc.subject.keyword Stroke
dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/PGC2018-099859-B-I00
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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