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Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis

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dc.contributor.author González-Ortega, I.
dc.contributor.author Cáceres, I.
dc.contributor.author Garnier Lacueva, Patrícia Carolina
dc.contributor.author Selva, G.
dc.date.accessioned 2021-03-01T07:52:05Z
dc.date.available 2021-03-01T07:52:05Z
dc.date.issued 2020
dc.identifier.citation González-Ortega I, González-Pinto A, Alberich S, Echeburúa E, Bernardo M, Cabrera B, et al. Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis. Psychol Med. 2020 Dec; 50(16): 2702-10. DOI: 10.1017/S0033291719002794
dc.identifier.issn 0033-2917
dc.identifier.uri http://hdl.handle.net/10230/46615
dc.description.abstract Background: Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the direction of their associations is not clear. Therefore, the main aim of this study was to analyze the influence of social cognition as a mediator between cognitive reserve and cognitive domains on functioning in FEP both at baseline and at 2 years. Methods: The sample of the study was composed of 282 FEP patients followed up for 2 years. To analyze whether social cognition mediates the influence of cognitive reserve and cognitive domains on functioning, a path analysis was performed. The statistical significance of any mediation effects was evaluated by bootstrap analysis. Results: At baseline, as neither cognitive reserve nor the cognitive domains studied were related to functioning, the conditions for mediation were not satisfied. Nevertheless, at 2 years of follow-up, social cognition acted as a mediator between cognitive reserve and functioning. Likewise, social cognition was a mediator between verbal memory and functional outcome. The results of the bootstrap analysis confirmed these significant mediations (95% bootstrapped CI (-10.215 to -0.337) and (-4.731 to -0.605) respectively). Conclusions: Cognitive reserve and neurocognition are related to functioning, and social cognition mediates in this relationship.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Cambridge University Press
dc.rights This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.title Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1017/S0033291719002794
dc.subject.keyword Cognitive reserve
dc.subject.keyword First episode psychosis
dc.subject.keyword Psychosocial functioning
dc.subject.keyword Social cognition
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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