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The high-quality genome sequence of the oceanic island endemic species drosophila guanche reveals signals of adaptive evolution in genes related to flight and genome stability

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dc.contributor.author Puerma, Eva
dc.contributor.author Orengo, Dorcas J.
dc.contributor.author Cruz, Fernando
dc.contributor.author Gómez Garrido, Jèssica
dc.contributor.author Librado, Pablo
dc.contributor.author Salguero, David
dc.contributor.author Papaceit, Montserrat
dc.contributor.author Gut, Marta
dc.contributor.author Segarra, Carmen
dc.contributor.author Alioto, Tyler
dc.contributor.author Aguadé, Montserrat
dc.date.accessioned 2019-11-20T08:48:35Z
dc.date.available 2019-11-20T08:48:35Z
dc.date.issued 2018
dc.identifier.citation Puerma E, Orengo DJ, Cruz F, Gómez-Garrido J, Librado P, Salguero D, Papaceit M, Gut M, Segarra C, Alioto TS, Aguadé M. The high-quality genome sequence of the oceanic island endemic species drosophila guanche reveals signals of adaptive evolution in genes related to flight and genome stability. Genome Biol Evol. 2018; 10(8):1956-1969. DOI 10.1093/gbe/evy135
dc.identifier.issn 1759-6653
dc.identifier.uri http://hdl.handle.net/10230/42905
dc.description.abstract Drosophila guanche is a member of the obscura group that originated in the Canary Islands archipelago upon its colonization by D. subobscura. It evolved into a new species in the laurisilva, a laurel forest present in wet regions that in the islands have only minor long-term weather fluctuations. Oceanic island endemic species such as D. guanche can become model species to investigate not only the relative role of drift and adaptation in speciation processes but also how population size affects nucleotide variation. Moreover, the previous identification of two satellite DNAs in D. guanche makes this species attractive for studying how centromeric DNA evolves. As a prerequisite for its establishment as a model species suitable to address all these questions, we generated a high-quality D. guanche genome sequence composed of 42 cytologically mapped scaffolds, which are assembled into six super-scaffolds (one per chromosome). The comparative analysis of the D. guanche proteome with that of twelve other Drosophila species identified 151 genes that were subject to adaptive evolution in the D. guanche lineage, with a subset of them being involved in flight and genome stability. For example, the Centromere Identifier (CID) protein, directly interacting with centromeric satellite DNA, shows signals of adaptation in this species. Both genomic analyses and FISH of the two satellites would support an ongoing replacement of centromeric satellite DNA in D. guanche.
dc.description.sponsorship This work was supported by grants BFU2012-35168 and BFU2015-63732 from Ministerio de Economía y Competitividad, Spain, and 2014SGR-1055 from Comissió Interdepartamental de Recerca i Innovació Tecnològica, Generalitat de Catalunya, Spain, to M.A.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Oxford University Press
dc.relation.ispartof Genome Biol Evol. 2018; 10(8):1956-1969
dc.rights © The Author(s) 2018. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
dc.title The high-quality genome sequence of the oceanic island endemic species drosophila guanche reveals signals of adaptive evolution in genes related to flight and genome stability
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1093/gbe/evy135
dc.subject.keyword Drosophila guanche
dc.subject.keyword De novo genome assembly
dc.subject.keyword Adaptation
dc.subject.keyword Centromere evolution
dc.subject.keyword Endemic species
dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/BFU2012-35168
dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/BFU2015-63732
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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