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The role of socioeconomic status in the association of lung function and air pollution-A pooled analysis of three adult ESCAPE cohorts

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dc.contributor.author Keidel, Dirk
dc.contributor.author Antó i Boqué, Josep Maria
dc.contributor.author Basagaña Flores, Xavier
dc.contributor.author Burte, Marthe-Emilie, 1989-
dc.contributor.author Carsin, Anne-Elie
dc.contributor.author Sunyer Deu, Jordi
dc.contributor.author Jacquemin Leonard, Bénédicte
dc.contributor.author Probst-Hensch, Nicole
dc.date.accessioned 2019-09-05T15:58:06Z
dc.date.available 2019-09-05T15:58:06Z
dc.date.issued 2019
dc.identifier.citation Keidel D, Anto JM, Basagaña X, Bono R, Burte E, Carsin AE et al. The role of socioeconomic status in the association of lung function and air pollution-A pooled analysis of three adult ESCAPE cohorts. Int J Environ Res Public Health. 2019;16(11):1901. DOI: 10.3390/ijerph16111901
dc.identifier.issn 1660-4601
dc.identifier.uri http://hdl.handle.net/10230/42246
dc.description.abstract Ambient air pollution is a leading environmental risk factor and its broad spectrum of adverse health effects includes a decrease in lung function. Socioeconomic status (SES) is known to be associated with both air pollution exposure and respiratory function. This study assesses the role of SES either as confounder or effect modifier of the association between ambient air pollution and lung function. Cross-sectional data from three European multicenter adult cohorts were pooled to assess factors associated with lung function, including annual means of home outdoor NO2. Pre-bronchodilator lung function was measured according to the ATS-criteria. Multiple mixed linear models with random intercepts for study areas were used. Three different factors (education, occupation and neighborhood unemployment rate) were considered to represent SES. NO2 exposure was negatively associated with lung function. Occupation and neighborhood unemployment rates were not associated with lung function. However, the inclusion of the SES-variable education improved the models and the air pollution-lung function associations got slightly stronger. NO2 associations with lung function were not substantially modified by SES-variables. In this multicenter European study we could show that SES plays a role as a confounder in the association of ambient NO2 exposure with lung function.
dc.description.sponsorship SAPALDIA Research support: The Swiss National Science Foundation (grants no 33CS30-177506/1, 33CS30-148470/1&2, 33CSCO-134276/1, 33CSCO-108796, 324730_135673, 3247BO-104283, 3247BO-104288, 3247BO-104284, 3247-065896, 3100-059302, 3200-052720, 3200-042532, 4026-028099, PMPDP3_129021/1, PMPDP3_141671/1), the Federal Office for the Environment, the Federal Office of Public Health, the Federal Office of Roads and Transport, the canton’s government of Aargau, Basel-Stadt, Basel-Land, Geneva, Luzern, Ticino, Valais, and Zürich, the Swiss Lung League, the canton’s Lung League of Basel Stadt/ Basel Landschaft, Geneva, Ticino, Valais, Graubünden and Zurich, Stiftung ehemals Bündner Heilstätten, SUVA, Freiwillige Akademische Gesellschaft, UBS Wealth Foundation, Talecris Biotherapeutics GmbH, Abbott Diagnostics, Klinik Barmelweid, Hirslanden Klinik Aarau, European Commission 018996 (GABRIEL), Wellcome Trust WT 084703MA, Exposomics EC FP7 grant(Grant agreement No: 308610).
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher MDPI
dc.relation.ispartof International Journal of Environmental Research and Public Health. 2019;16(11):1901
dc.rights © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.title The role of socioeconomic status in the association of lung function and air pollution-A pooled analysis of three adult ESCAPE cohorts
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.3390/ijerph16111901
dc.subject.keyword Europe
dc.subject.keyword Socioeconomic position
dc.subject.keyword Air pollution
dc.subject.keyword Environmental equality
dc.subject.keyword Lung function
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/308610
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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