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dc.contributor.author | Rodríguez-Fernández, Sonia |
dc.contributor.author | Castillo-Lorente, Encarnación |
dc.contributor.author | Guerrero-López, Francisco |
dc.contributor.author | Rodríguez-Rubio, David |
dc.contributor.author | Aguilar-Alonso, Eduardo |
dc.contributor.author | Lafuente Baraza, Jesus |
dc.contributor.author | Gómez-Jiménez, Francisco Javier |
dc.contributor.author | Mora-Ordoñez, Juan |
dc.contributor.author | Rivera-López, Ricardo |
dc.contributor.author | Arias-Verdú, María Dolores |
dc.contributor.author | Quesada-García, Guillermo |
dc.contributor.author | Arráez-Sánchez, Miguel Ángel |
dc.contributor.author | Rivera-Fernández, Ricardo |
dc.date.accessioned | 2019-03-15T08:23:34Z |
dc.date.available | 2019-03-15T08:23:34Z |
dc.date.issued | 2018 |
dc.identifier.citation | Rodríguez-Fernández S, Castillo-Lorente E, Guerrero-Lopez F, Rodríguez-Rubio D, Aguilar-Alonso E, Lafuente-Baraza J. et al. Validation of the ICH score in patients with spontaneous intracerebral haemorrhage admitted to the intensive care unit in Southern Spain. BMJ Open. 2018 Aug 13;8(8):e021719. DOI: 10.1136/bmjopen-2018-021719 |
dc.identifier.issn | 2044-6055 |
dc.identifier.uri | http://hdl.handle.net/10230/36840 |
dc.description.abstract | OBJECTIVE: Validation of the intracerebral haemorrhage (ICH) score in patients with a diagnosis of spontaneous ICH admitted to the intensive care unit (ICU). METHODS: A multicentre cohort study was conducted in all consecutive patients with ICH admitted to the ICUs of three hospitals with a neurosurgery department between 2009 and 2012 in Andalusia, Spain. Data collected included ICH, Glasgow Coma Scale (GCS) and Acute Physiology and Chronic Health Evaluation II (APACHE-II) scores. Demographic data, location and volume of haematoma and 30-day mortality rate were also collated. RESULTS: A total of 336 patients were included. 105 of whom underwent surgery. Median (IQR) age: 62 (50-70) years. APACHE-II: 21(15-26) points, GCS: 7 (4-11) points, ICH score: 2 (2-3) points. 11.1% presented with bilateral mydriasis on admission (mortality rate=100%). Intraventricular haemorrhage was observed in 58.9% of patients. In-hospital mortality was 54.17% while the APACHE-II predicted mortality was 57.22% with a standardised mortality ratio (SMR) of 0.95 (95% CI 0.81 to 1.09) and a Hosmer-Lemenshow test value (H) of 3.62 (no significant statistical difference, n.s.). 30-day mortality was 52.38% compared with the ICH score predicted mortality of 48.79%, SMR: 1.07 (95% CI 0.91 to 1.23), n.s. Mortality was higher than predicted at the lowest scores and lower than predicted in the more severe patients, (H=55.89, p<0.001), Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva calibration belt (p<0.001). The area under a receiver operating characteristic (ROC) curve was 0.74 (95% CI 0.69 to 0.79). CONCLUSIONS: ICH score shows an acceptable discrimination as a tool to predict mortality rates in patients with spontaneous ICH admitted to the ICU, but its calibration is suboptimal. |
dc.format.mimetype | application/pdf |
dc.language.iso | eng |
dc.publisher | BMJ Publishing Group |
dc.relation.ispartof | BMJ Open. 2018 Aug 13;8(8):e021719 |
dc.rights | This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ |
dc.subject.other | Hemorràgia cerebral |
dc.title | Validation of the ICH score in patients with spontaneous intracerebral haemorrhage admitted to the intensive care unit in Southern Spain |
dc.type | info:eu-repo/semantics/article |
dc.identifier.doi | http://dx.doi.org/10.1136/bmjopen-2018-021719 |
dc.subject.keyword | ICH score |
dc.subject.keyword | ICU |
dc.subject.keyword | Intracerebral haemorrhage |
dc.subject.keyword | Mortality |
dc.subject.keyword | Prognostic model |
dc.rights.accessRights | info:eu-repo/semantics/openAccess |
dc.type.version | info:eu-repo/semantics/publishedVersion |