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Association between socioeconomic deprivation and colorectal cancer screening outcomes: Low uptake rates among the most and least deprived people

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dc.contributor.author Buron Pust, Andrea
dc.contributor.author Auge, Josep M.
dc.contributor.author Sala Serra, Maria
dc.contributor.author Román, Marta
dc.contributor.author Castells, Antoni
dc.contributor.author Macià Guilà, Francesc Assís
dc.contributor.author Comas Serrano, Mercè
dc.contributor.author Guiriguet, Carolina
dc.contributor.author Bessa Caserras, Xavier
dc.contributor.author Castells, Xavier
dc.contributor.author PROCOLON research group
dc.date.accessioned 2018-07-17T07:34:13Z
dc.date.available 2018-07-17T07:34:13Z
dc.date.issued 2017
dc.identifier.citation Buron A, Auge JM, Sala M, Román M, Castells A, Macià F. et al. Association between socioeconomic deprivation and colorectal cancer screening outcomes: Low uptake rates among the most and least deprived people. PLoS One. 2017 Jun 16;12(6):e0179864. DOI: 10.1371/journal.pone.0179864
dc.identifier.issn 1932-6203
dc.identifier.uri http://hdl.handle.net/10230/35170
dc.description.abstract BACKGROUND: Screening with faecal occult blood tests reduces colorectal cancer-related mortality; however, age, sex and socioeconomic factors affect screening outcomes and could lead to unequal mortality benefits. The aim of this study was to describe the main outcomes of the population-based Barcelona colorectal cancer screening programme (BCRCSP) by deprivation. METHODS: Retrospective study of the eligible population of the first round of the BCRCSP. Participants' postal addresses were linked with the MEDEA database to obtain the deprivation quintiles (Dq). Chi-squared tests were used to compare proportions across variables and logistic regression was used to estimate the adjusted effects of age, sex and deprivation on uptake, FIT positivity, colonoscopy adherence and advanced neoplasia detection rate. RESULTS: Overall uptake was 44.7%, higher in Dq2, 3 and 4 (OR 1.251, 1.250 and 1.276, respectively) than in the least deprived quintile (Dq 1), and lowest in Dq5 (OR 0.84). Faecal immunochemical test (FIT) positivity and the percentage of people with detectable faecal haemoglobin below the positivity threshold increased with deprivation. The advanced neoplasia detection rate was highest in Dq4. CONCLUSION: Unlike most regions where inequalities are graded along the socioeconomic continuum, inequalities in the uptake of colorectal cancer screening in Spain seem to be concentrated first in the most disadvantaged group and second in the least deprived group. The correlation of deprivation with FIT-positivity and faecal haemoglobin below the positivity threshold is worrying due to its association with colorectal cancer and overall mortality.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Public Library of Science (PLoS)
dc.relation.ispartof PLoS One. 2017 Jun 16;12(6):e0179864
dc.rights Copyright © 2017 Buron et al. This is an open access article distributed under the terms of the https://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject.other Còlon -- Càncer -- Prevenció
dc.title Association between socioeconomic deprivation and colorectal cancer screening outcomes: Low uptake rates among the most and least deprived people
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0179864
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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