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Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys

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dc.contributor.author McLaughlin, Katie A.
dc.contributor.author Alonso Caballero, Jordi
dc.contributor.author Kessler, Ronald C.
dc.date.accessioned 2018-04-25T07:22:28Z
dc.date.issued 2017
dc.identifier.citation McLaughlin KA, Koenen KC, Bromet EJ, Karam EG, Liu H, Petukhova M et al. Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys. Br J Psychiatry. 2017 Nov;211(5):280-8. DOI: 10.1192/bjp.bp.116.197640
dc.identifier.issn 0007-1250
dc.identifier.uri http://hdl.handle.net/10230/34441
dc.description.abstract Background: Although childhood adversities are known to predict increased risk of post-traumatic stress disorder (PTSD) after traumatic experiences, it is unclear whether this association varies by childhood adversity or traumatic experience types or by age.AimsTo examine variation in associations of childhood adversities with PTSD according to childhood adversity types, traumatic experience types and life-course stage. Method: Epidemiological data were analysed from the World Mental Health Surveys (n = 27 017).ResultsFour childhood adversities (physical and sexual abuse, neglect, parent psychopathology) were associated with similarly increased odds of PTSD following traumatic experiences (odds ratio (OR) = 1.8), whereas the other eight childhood adversities assessed did not predict PTSD. Childhood adversity-PTSD associations did not vary across traumatic experience types, but were stronger in childhood-adolescence and early-middle adulthood than later adulthood. Conclusions: Childhood adversities are differentially associated with PTSD, with the strongest associations in childhood-adolescence and early-middle adulthood. Consistency of associations across traumatic experience types suggests that childhood adversities are associated with generalised vulnerability to PTSD following traumatic experiences.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Cambridge University Press
dc.relation.ispartof British Journal of Psychiatry. 2017 Nov;211(5):280-8
dc.rights © Cambridge University Press. The published version of the article: McLaughlin KA, Koenen KC, Bromet EJ, Karam EG, Liu H, Petukhova M. et al. Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys. Br J Psychiatry. 2017 Nov;211(5):280-288 is available at https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry.
dc.subject.other Trastorn per estrès posttraumàtic -- Infants
dc.subject.other Infants -- Salut mental
dc.title Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1192/bjp.bp.116.197640
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion

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