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Increased nucleus accumbens volume in first-episode psychosis

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dc.contributor.author Forns-Nadal, Mireia
dc.contributor.author Berge Baquero, Daniel
dc.contributor.author Seme, Federico
dc.contributor.author Mané Santacana, Anna
dc.contributor.author Igual, Laura
dc.contributor.author Guinart, Dani
dc.contributor.author Vilarroya, Óscar
dc.date.accessioned 2018-03-01T08:33:56Z
dc.date.issued 2017
dc.identifier.citation Forns-Nadal M, Bergé D, Sem F, Mané A, Igual L, Guinart D. et al. Increased nucleus accumbens volume in first-episode psychosis. Psychiatry Res. 2017 May 30;263:57-60. DOI: 10.1016/j.pscychresns.2017.03.007
dc.identifier.issn 0165-1781
dc.identifier.uri http://hdl.handle.net/10230/34021
dc.description.abstract Nucleus accumbens has been reported as a key structure in the neurobiology of schizophrenia. Studies analyzing structural abnormalities have shown conflicting results, possibly related to confounding factors. We investigated the nucleus accumbens volume using manual delimitation in first-episode psychosis (FEP) controlling for age, cannabis use and medication. Thirty-one FEP subjects who were naive or minimally exposed to antipsychotics and a control group were MRI scanned and clinically assessed from baseline to 6 months of follow-up. FEP showed increased relative and total accumbens volumes. Clinical correlations with negative symptoms, duration of untreated psychosis and cannabis use were not significant.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartof Psychiatry Research. 2017 May 30;263:57-60
dc.rights © Elsevier http://dx.doi.org/10.1016/j.pscychresns.2017.03.007
dc.subject.other Esquizofrènia
dc.subject.other Psicosi
dc.title Increased nucleus accumbens volume in first-episode psychosis
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1016/j.pscychresns.2017.03.007
dc.subject.keyword Neuroimaging
dc.subject.keyword Region of interest
dc.subject.keyword Reward
dc.subject.keyword Schizophrenia
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion


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