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Sex-related differences in primary intracerebral hemorrhage

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dc.contributor.author Roquer, Jaume
dc.contributor.author Rodriguez Campello, Ana
dc.contributor.author Jimenez-Conde, Jordi
dc.contributor.author Cuadrado Godia, Elisa
dc.contributor.author Giralt-Steinhauer, Eva
dc.contributor.author Vivanco Hidalgo, Rosa María
dc.contributor.author Soriano Tarraga, Carolina
dc.contributor.author Ois Santiago, Angel Javier
dc.date.accessioned 2017-11-28T08:16:36Z
dc.date.available 2017-11-28T08:16:36Z
dc.date.issued 2016
dc.identifier.citation Roquer J, Rodríguez-Campello A, Jiménez-Conde J, Cuadrado-Godia E, Giralt-Steinhauer E, Vivanco Hidalgo RM. Et al. Sex-related differences in primary intracerebral hemorrhage. Neurology. 2016 Jul 19;87(3):257-62. DOI: 10.1212/WNL.0000000000002792
dc.identifier.issn 0028-3878
dc.identifier.uri http://hdl.handle.net/10230/33359
dc.description.abstract OBJECTIVE: Little information is available about sex-related differences in intracerebral hemorrhage (ICH). This is a prospective observational study to describe the sex differences in demographics, vascular risk factors, stroke care, and outcomes in primary ICH. METHODS: BasicMar is a hospital-based registry of all stroke patients admitted to a single public hospital that covers a population of 330,000. From 2005 to 2015, there were 515 consecutive acute primary ICH patients. Outcome data were obtained at 3 months. RESULTS: More men than women had ICH (52.4% vs 47.6%); the women were older and had worse previous functional status than men, who were more likely to drink alcohol and smoke and to have ischemic heart disease and peripheral arterial disease. There were no sex differences in etiology, severity, or hemorrhage volume. ICH score was greater in women than in men (p = 0.018). Women had more lobar ICH than men (odds ratio adjusted by age was 1.75 [95% confidence interval 1.18-2.58], p = 0.005). The quality of stroke care was similar in both sexes. Mortality at 3 months was 44.1% in women and 41.1% in men (p = 0.656), and 3-month poor outcome among survivors (modified Rankin Scale [mRS] score 3-5) 58.4% in women and 45.3% in men (p = 0.027). After adjustment for previous mRS and ICH score, there were no differences in 3-month mortality or poor outcome at 3 months between sexes. CONCLUSIONS: Patients with ICH showed sex-related differences in demographic characteristics, ICH location, and vascular risk factors, but not in stroke care, 3-month mortality, or adjusted poor outcome.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Lippincott Williams & Wilkins
dc.rights © Lippincott Williams & Wilkins "This is a non-final version of an article published in final form in Roquer J, Rodríguez-Campello A, Jiménez-Conde J, Cuadrado-Godia E, Giralt-Steinhauer E, Vivanco Hidalgo RM. Et al. Sex-related differences in primary intracerebral hemorrhage. Neurology. 2016 Jul 19;87(3):257-62. ". http://dx.doi.org/DOI: 10.1212/WNL.0000000000002792
dc.subject.other Malalties cerebrovasculars
dc.title Sex-related differences in primary intracerebral hemorrhage
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1212/WNL.0000000000002792
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion


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