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Databases and resources for human small non-coding RNAs

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dc.contributor.author Agirre Ortiz de Guzmán, Eneritz, 1983-
dc.contributor.author Eyras Jiménez, Eduardo
dc.date.accessioned 2015-12-18T15:16:52Z
dc.date.available 2015-12-18T15:16:52Z
dc.date.issued 2011
dc.identifier.citation Agirre E, Eyras E. Databases and resources for human small non-coding RNAs. Human Genomics. 2011; 5(3): 192-199. DOI 10.1186/1479-7364-5-3-192
dc.identifier.issn 1479-7364
dc.identifier.uri http://hdl.handle.net/10230/25476
dc.description.abstract Recent advances in high-throughput sequencing have facilitated the genome-wide studies of small non-coding RNAs (sRNAs). Numerous studies have highlighted the role of various classes of sRNAs at different levels of gene regulation and disease. The fast growth of sequence data and the diversity of sRNA species have prompted the need to organise them in annotation databases. There are currently several databases that collect sRNA data. Various tools are provided for access, with special emphasis on the well-characterised family of micro-RNAs. The striking heterogeneity of the new classes of sRNAs and the lack of sufficient functional annotation, however, make integration of these datasets a difficult task. This review describes the currently available databases for human sRNAs that are accessible via the internet, and some of the large datasets for human sRNAs from high-throughput sequencing experiments that are so far only available as supplementary data in publications. Some of the main issues related to the integration and annotation of sRNA datasets are also discussed.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher BioMed Central
dc.relation.ispartof Human Genomics. 2011; 5(3): 192-199
dc.rights © 2011 Henry Stewart Publications. This is an Open Access article distributed under the terms of a Creative Commons Attribution License
dc.subject.other RNA
dc.subject.other Bases de dades
dc.subject.other Biologia computacional
dc.title Databases and resources for human small non-coding RNAs
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1186/1479-7364-5-3-192
dc.subject.keyword MiRNAs
dc.subject.keyword Small RNAs
dc.subject.keyword Non-coding RNAs
dc.subject.keyword High-throughput sequencing
dc.subject.keyword Databases
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion


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