Status epilepticus is a condition in which the brain is in a state of seizure activity without
returning to its basal state for more than 5 minutes. Medication is the usual treatment,
but when it is ineffective, surgical ...
Deformable medical image registration and automatic segmentation are essential
procedures in many image analysis applications, such as in early detection and
monitoring of fetal and neonatal brain development. Nowadays ...
Aortic coarctation (AoC) is a challenging congenital heart disease (CHD) to
diagnose prenatally, accounting for 6-8% of all CHDs. It involves the narrowing of a
segment of the aortic arch, typically affecting the aortic ...
Sleep is a natural, recurring state of rest and unconsciousness in which the body
and mind undergo a series of physiological and neurological changes. It is divided
in 4 stages: REM, N1, N2 and N3, also called deep sleep, ...
Psychotic disorders present significant challenges in understanding their causes and
developing effective interventions. Functional magnetic resonance imaging (fMRI)
has become a valuable tool for investigating these ...
Epilepsy is a chronic neurological disease characterized by recurring seizures. While
most epileptic patients can manage their condition with antiseizure drugs, approximately
25% of individuals experience drug-resistant ...
Pulmonary embolism (PE) is a cardiovascular disease caused by one or several occlusions
in the pulmonary arteries. Its diagnosis is mainly reliant on imaging, being
computerized tomography pulmonary angiogram the gold ...
Hypertrophic cardiomyopathy (HCM) is a condition characterized by an abnormal
thickening of the myocardium resulting in impaired blood pumping efficiency of the
heart. HCM exhibits clinical variability, with diverse ...
Psychotic disorders are characterized by the presence of symptoms related to a distortion of one’s perception of reality. In its early stages (First Episode of Psychosis,
FEP), patients may show diffuse symptomatology ...
Psychosis can be described as an alteration in brain connectivity that leads to an
impairment of cognition and the speed at which the information gets processed,
what causes a diversity of psychiatric symptoms. This ...
Multiple sclerosis (MS) is a neurodegenerative disease affecting the central nervous
system (CNS), characterized by the destruction of myelin sheaths, that has become
the leading cause of disability in young adults. Since ...
Arterial blood pressure is a crucial indicator for cardiac conditions like hypertension,
heart failure, strokes and limb ischemia. Current wireless devices diagnose heart failure
through blood pressure measurement. ...
Left ventricular hypertrophy (LVH) consists of the thickening of the myocardium,
significantly increasing the risk of cardiovascular events. LVH can be attributed to
various etiologies, each with distinct prognoses and ...
Around 80% of world population will suffer of low back pain (LBP). Such condition is
often related with intervertebral disc (IVD) degeneration (DD). In DD, the proteoglycan
(PG) loss is highly important since it compromises ...
Transcatheter aortic valve implantation (TAVI) is a minimally invasive heart procedure
that has emerged as a safe and effective treatment for patients with severe
symptomatic aortic stenosis (AS). This is a common heart ...
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia, yet understanding its
causes and finding effective treatments remains a challenge. To address this, researchers
are developing innovative approaches based on ...
The use of computational brain models in epilepsy constitutes a powerful tool not
only to improve our understanding of the disease, but also to optimize and personalize
treatments in silico. In this direction, properly ...
A cleft lip and palate are congenital defects that occur when the tissues of the
face and mouth do not fuse properly during fetal development. These defects often
require the use of bone grafts to achieve successful ...
End-stage renal disease (ESRD) is a life-threatening condition that affects over 10%
of the global population, necessitating hemodialysis (HD) for patients awaiting a
kidney transplant. The arteriovenous fistula (AVF) ...
Knee osteoarthritis (OA) is one of the most prevalent forms of arthritis and one of the
leading causes of disability. The pathological traits consist of articular cartilage
degradation and bone thickening, among other ...