• Assesment of 4D aortic strain from 3D time-resolved MRI in aortic aneurysms

  Xicoira Serra, Marina (2021-07)

  Aortic aneurysms are a class of frequent cardiovascular disease related to an increased risk of life-threating complications, such as aortic dissection and rupture. These acute events are characterized by a very bad ...
• A novel approach to assess Alzheimer’s Disease by using radiomics in TgF344-AD rats: Development and application of radiomic features as imaging biomarkers to evaluate the different stages of Alzheimer’s disease

  Sorribes Torrent, Elisabet (2021-07)

  Alzheimer’s disease (AD) is a complex neurodegenerative disease that leads to progressive cognitive decline and memory loss. Nowadays, it is still very challenging to diagnose AD due to its complexity, the inter-individual ...
• Engineering Escherichia coli for survival in Outer Space conditions: Enhancing bacterial resistance to extreme levels of radiation, temperature, and pressure

  Puig Costa-Jussà, Jaume (2021-07)

  Some bacteria have shown the ability to naturally survive to extreme environments, even Outer Space. These bacteria have natural genetic mechanisms to protect and repair the DNA damage these severe conditions can cause, ...
• Cutibacterium acnes-derived extracellular vesicles: characterization and modulation of the skin immune response

  Pol Cros, Maria (2021-07)

  The human microbiome plays an essential role in maintaining the host health. One of the most common bacteria present in the skin microbiota is Cutibacterium acnes (C.acnes) which is known for being involved in the homeostasis ...
• Automatic detection of new lesions in patients with multiple sclerosis using the T1-w/T2-w magnetic resonance ratio

  Pérez Sánchez, Laura (2021-07)

  Multiple sclerosis is an autoimmune condition in which the immune system mistakenly attacks the myelin sheath, causing that messages travelling along the nerves become slowed or disrupted. Currently, the severity of the ...
• Pharmacological experiment on neurodegeneration in mature trisomic mouse models: Assessment of the neurodegenerative phenotype and its potential modulation in a middle-aged mouse model of Down syndrome

  Pérez García, Silvia (2021-07)

  Down syndrome (DS) is the most common cause of intellectual disability and a genetic cause of early Alzheimer’s disease, produced by trisomy of whole or part of chromosome 21. Nevertheless, no gold-standard clinical treatment ...
• A computational model for collective chondrocyte behaviour in osteoarthritis, in patient-specific biochemical micro-environments

  Pascuet Fontanet, Andreu (2021-07)

  Osteoarthritis (OA) is a common condition characterised by the degradation of the articular cartilage that leads to stiff and painful joints. OA is related with the dysregulation of the cartilage chondrocyte’s activity, ...
• Hip joint space analysis for osteoarthritis diagnosis

  Palacios Peral, Laura (2021-07)

  The hip joint is one of the body’s largest weight-bearing joints and is commonly affected by osteoarthritis (OA). With hip osteoarthritis the cartilage within the joint begins to break down and the underlying bone begins ...
• Mode and tempo of cultural evolution in video games

  Ortiz Sánchez, Ivan Dmitriy (2021-07)

  The mechanisms of biological evolution also apply to artificial phenomena such as culture and technology, and the evolution of video games through history has been shaped by the evolution of technology itself. In particular, ...
• Modelling immunogenicity in heterogeneous cancer cells under the immune system action

  Orrit Viñets, Laura (2021-07)

  Tumor cells heterogeneity is one of the most important handicaps in fighting cancer. Such heterogeneity is mainly driven by genomic instability, epigenetics and different sources of stochasticity. Heterogeneity provides ...
• Auricular transcutaneous vagus nerve stimulation device in the form of an ear pod for mice: A first step towards chronic non-invasive auricular vagus nerve stimulation in animal models

  Navarro Guimerà, Sergi (2021-07)

  The pro-cognitive effects of Vagus Nerve Stimulation (VNS) observed in some small offlabel studies have raised enthusiasm for its use to ameliorate cognitive performance. Relatedly, auricular transcutaneous VNS (atVNS) has ...
• Gene expression remotely controlled by an electronic device using a thermal interface

  Martinez Gonzalez, Judith (2021-07)

  Synthetic biology is a field of Biology that involves redesigning organisms for useful purposes by rationally engineering them to have new abilities. The potential to reengineer living organisms has provided tools to address ...
• The role of whole genome doubling in cancer evolution

  Martí Baena, Quim (2021-07)

  Whole genome doubling (WGD) is one of the most common events in the early stages of cancer evolution. However, a consistent explanation for the pervasiveness of WGD across cancer types remains elusive. The duplication of ...
• Alteration in nerve function following electroporation: A numerical modeling study of the electroporation conductance effect

  Marcoval i Martínez, Sergi (2021-07)

  It is known that, after the application of sufficiently high external electric fields, defects are formed in the cell membrane at the molecular level, non-selectively increasing its permeability, and therefore increasing ...
• Scaling of a full three-dimensional knee joint model for the study of osteoarthritis: towards developing a patient-specific model

  Loayza Saldaña, Mayra Alejandra (2021-07)

  Articular cartilage degeneration is consequence of knee osteoarthritis (OA). There is not a clear aetiology or understanding of OA’s natural course since it is a multifactorial condition. Finite Element models can be used ...
• A first study for the establishment of a source of vitamin B12 as of the genetic modification of the Cyanobacteria Arthrospira platensis

  Lechuga Morente, Daniel (2021-07)

  Cobalamin de novo synthesis appears to be restricted solely to some bacteria and archaea. In humans, this nutrient is usually acquired through the consumption of animal products. However, it can lead to a vitamin B12 ...
• In-silico modelling of the deployment of left atrial appendage occluder devices: A sensitivity analysis

  Iglesias Blanco, Marian (2021-07)

  Percutaneous left atrial appendage (LAA) occlusion interventions are an alternative to oral anticoagulants for cardioembolic stroke prevention in atrial fibrillation patients. Preoperative insights into how the occluder ...
• Occipital alpha oscillations and sex differences

  González Alonso, Sandra (2021-07)

  Ever since the first measurements of the human electroencephalogram, it is known that neural activity in the alpha frequency (~10Hz) is dominant during relaxed wakefulness. The frequency peak of alpha varies between ...
• SleepBCI: a platform for sleep quality assessment and memory enhancement based on automatic scoring

  Esparza Iaizzo, Martín E. (2021-07)

  Sleep is a complex physiological process responsible for several developmental, restorative and cognitive processes. Sleep related disorders diminish life quality, and their diagnosis relies on classifying 8-hour ...
• Sensitivity analysis to haemodynamic boundary conditions in human coronary arteries

  Domínguez Gómez, Paula (2021-07)

  Advances in medical imaging and computational power have led to the emergence of patient-specific computational modelling for non-invasive coronary stenosis severity assessment. Computational fluid dynamics (CFD) models ...

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