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MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae

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dc.contributor.author Wodke, Judith A.H.
dc.contributor.author Alibés, Andreu
dc.contributor.author Cozzuto, Luca
dc.contributor.author Hermoso Pulido, Antonio
dc.contributor.author Yus, Eva
dc.contributor.author Lluch-Senar, Maria 1982-
dc.contributor.author Serrano Pubull, Luis, 1982-
dc.contributor.author Roma, Guglielmo
dc.date.accessioned 2015-11-17T14:35:55Z
dc.date.available 2015-11-17T14:35:55Z
dc.date.issued 2015
dc.identifier.citation Wodke JA, Alibés A, Cozzuto L, Hermoso A, Yus E, Lluch-Senar M et al. MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae. Nucleic acids research. 2015; 43: D618-D623. DOI 10.1093/nar/gku1105
dc.identifier.issn 0305-1048
dc.identifier.uri http://hdl.handle.net/10230/25116
dc.description.abstract MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. Due to its small size, its ability to grow in vitro, and the amount of data produced over the past decades, M. pneumoniae is an interesting model organisms for the development of systems biology approaches for unicellular organisms. Our database hosts a wealth of omics-scale datasets generated by hundreds of experimental and computational analyses. These include data obtained from gene expression profiling experiments, gene essentiality studies, protein abundance profiling, protein complex analysis, metabolic reactions and network modeling, cell growth experiments, comparative genomics and 3D tomography. In addition, the intuitive web interface provides access to several visualization and analysis tools as well as to different data search options. The availability and--even more relevant--the accessibility of properly structured and organized data are of up-most importance when aiming to understand the biology of an organism on a global scale. Therefore, MyMpn constitutes a unique and valuable new resource for the large systems biology and microbiology community.
dc.description.sponsorship European Union through the European Research Council (ERC) [‘Celldoctor’ GA 232913]; Spanish Ministerio de Economía y Competitividad Plan Nacional [BIO2007-61762]; Fundaci´on Marcelino Botin [to L.S.]. laCaixa-CRG Fellowship, Fundació laCaixa [to J.W.]; Spanish Ministry of Economy and Competitiveness No [PTA2010-4446-I to A.H.; PTA2011-6729-I to L.C.]. Funding for open access charge: ERC [to L.S.].
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Oxford University Press
dc.relation.ispartof Nucleic acids research. 2015; 43: D618-D623
dc.rights © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. this is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
dc.subject.other Mycoplasma pneumoniae -- Aspectes genètics
dc.subject.other Mycoplasma pneumoniae -- Metabolisme
dc.subject.other Genètica bacteriana
dc.subject.other Genomes bacterians
dc.subject.other Bases de dades
dc.title MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1093/nar/gku1105
dc.relation.projectID info:eu-repo/grantAgreement/EC/ERC/232913
dc.relation.projectID info:eu-repo/grantAgreement/ES/2PN/BIO2007-61762
dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/PTA2010-4446
dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/PTA2011-6729
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/acceptedVersion


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