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Data from proteomic characterization of the role of Snail1 in murine mesenchymal stem cells and 3T3-L1 fibroblasts differentiation.

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dc.contributor.author Peláez García, Alberto
dc.contributor.author Barderas, Rodrigo
dc.contributor.author Mendes, Marta
dc.contributor.author López Lucendo, María
dc.contributor.author Sanchez, J.C.
dc.contributor.author García de Herreros, Antonio
dc.contributor.author Casal, José Ignacio
dc.date.accessioned 2015-10-20T08:58:42Z
dc.date.available 2015-10-20T08:58:42Z
dc.date.issued 2015
dc.identifier.citation Peláez-García A, Barderas R, Mendes M, Lopez-Lucendo M, Sanchez JC, García de Herreros A. et al. Data from proteomic characterization of the role of Snail1 in murine mesenchymal stem cells and 3T3-L1 fibroblasts differentiation. Data Brief. 2015 Jul 31;4:606-13. doi: 10.1016/j.dib.2015.07.027.
dc.identifier.issn 2352-3409
dc.identifier.uri http://hdl.handle.net/10230/24860
dc.description.abstract The transcription factor (TF) Snail1 is a major inducer of the epithelial-mesenchymal transition (EMT) during embryonic development and cancer progression. Ectopic expression of Snail in murine mesenchymal stem cells (mMSC) abrogated their differentiation to osteoblasts or adipocytes. We used either stable isotopic metabolic labeling (SILAC) for 3T3-L1 cells or isobaric labeling with tandem mass tags (TMT) for mMSC stably transfected cells with Snail1 or control. We carried out a proteomic analysis on the nuclear fraction since Snail is a nuclear TF that mediates its effects mainly through the regulation of other TFs. Proteomics data have been deposited in ProteomeXchange via the PRIDE partner repository with the dataset identifiers PXD001529 and PXD002157 (Vizcaino et al., 2014) [1]. Data are associated with a research article published in Molecular and Cellular Proteomics (Pelaez-Garcia et al., 2015) [2].
dc.description.sponsorship Alberto Peláez-García was a recipient of a FPI fellowship. Rodrigo Barderas was supported by the Ramón y Cajal Programme of the Spanish Ministry of Economy and Competitiveness (MINECO). This research was supported by grants to established research groups (AECC), BIO2012-31023 from the Spanish Ministry of Economy and Competitiveness, S2011/BMD-2344/ (Colomics2) from Comunidad de Madrid and Grant PRB2 (IPT13/0001 – ISCIII-SGEFI/FEDER) from ProteoRed-ISCIII.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartof Data in Brief. 2015 Jul 31;4:606-13
dc.rights c)2015 Peláez-García A, Barderas R, Mendes M, Lopez-Lucendo M, Sanchez JC, García de Herreros A, Casal JI. Published by Elsevier Inc. This is an openaccess article under the CC BY license(http://creativecommons.org/licenses/by/4.0/)
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.subject.other Cèl·lules mare mesenquimàtiques
dc.subject.other Càncer
dc.title Data from proteomic characterization of the role of Snail1 in murine mesenchymal stem cells and 3T3-L1 fibroblasts differentiation.
dc.type info:eu-repo/semantics/article
dc.identifier.doi http://dx.doi.org/10.1016/j.dib.2015.07.027
dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/BIO2012-31023
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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