• Determination of well-being-related markers in nails by liquid chromatography tandem mass spectrometry

  Gómez-Gómez, Àlex; Montero-San Martin, Blanca; Haro, Noemí; Pozo Mendoza, Óscar J., 1975- (Elsevier, 2023)

  Well-being is a multifactorial positive state that is highly influenced by some endogenous molecules that control happiness and euphoric feelings. These molecules, e.g., neurotransmitters, hormones and their derivatives, ...
• Other malignancies in the history of CLL: an international multicenter study conducted by ERIC, the European Research Initiative on CLL, in HARMONY

  Chatzikonstantinou, Thomas; Gimeno Vázquez, Eva; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Stamatopoulos, Kostas (Elsevier, 2023)

  Background: Patients with chronic lymphocytic leukemia (CLL) have a higher risk of developing other malignancies (OMs) compared to the general population. However, the impact of CLL-related risk factors and CLL-directed ...
• Painful hemorrhage of vestibular papillae: A probably underreported complication of vestibular papillomatosis

  López Trujillo, Emilio; Segura Tigell, Sonia; Sánchez-Schmidt, Julia Maria (Mattioli 1885, 2024)
• Biomarker and pharmacodynamic activity of the transforming growth factor-beta (TGFβ) inhibitor SAR439459 as monotherapy and in combination with cemiplimab in a phase I clinical study in patients with advanced solid tumors

  Robbrecht, Debbie; Rodriguez-Vida, Alejo; Wang, Rui (Wiley, 2024)

  SAR439459, a 'second-generation' human anti-transforming growth factor-beta (TGFβ) monoclonal antibody, inhibits all TGFβ isoforms and improves the antitumor activity of anti-programmed cell death protein-1 therapeutics. ...
• Sensitization to textile dyes in Spain: Epidemiological situation (2019-2022)

  Hernández Fernández, Carlos Pelayo; Giménez Arnau, Anna Maria; García Doval, Ignacio (Wiley, 2024)

  Background: Current frequency and features for positivity to textile dye mix (TDM) in Spain are unknown. Objectives: To study the frequency, clinical features and simultaneous positivity between TDM, para-phenylenediamine ...
• A machine learning approach to identify groups of patients with hematological malignant disorders

  Rodríguez-Belenguer, Pablo; Piñana, José Luis; Sánchez Montañés, Manuel; Soria Olivas, Emilio; Martínez Sober, Marcelino; Serrano López, Antonio J. (Elsevier, 2024)

  Background and objective: Vaccination against SARS-CoV-2 in immunocompromised patients with hematologic malignancies (HM) is crucial to reduce the severity of COVID-19. Despite vaccination efforts, over a third of HM ...
• Exploratory analyses of treatment subgroup interaction by PD-L1 status and according to PD-L1 expression in the JAVELIN Bladder 100 trial

  Climent, Miguel Ángel; Álvarez, Carlos; Morales-Barrera, Rafael; Maroto, Pablo; Rodríguez-Vida, Alejo; Méndez-Vidal, María José; García del Muro, Xavier; Puente, Javier; Láinez, Nuria; Vázquez, Sergio; Castellano, Daniel; Gómez Lang, Carmen; Wang, Jing; Di Pietro, Alessandra; Davis, Craig; Sanz Castillo, Belén; Bolós, M. Victoria; Valderrama, Begoña P. (Springer, 2024)

  Purpose: Post hoc analysis of the JAVELIN Bladder 100 trial of avelumab maintenance in locally advanced/metastatic urothelial carcinoma (la/mUC) to determine the interaction by programmed death ligand 1 (PD-L1) status for ...
• Tubulo-interstitial inflammation increases the risk of graft loss after the recurrence of IgA nephropathy

  Rodrigo Calabia, Emilio; Quintana, Luis; Vázquez Sánchez, Teresa; Sánchez Fructuoso, Ana; Buxeda, Anna; Gavela, Eva; Cazorla, Juan M.; Cabello, Sheila; Beneyto, Maria Isabel; López-Oliva, Maria O.; Diekmann, Fritz; Gómez Ortega, José M.; Calvo Romero, Natividad; Pérez-Sáez, María José; Sancho, Asunción; Mazuecos, Auxiliadora; Espí Reig, Jordi; Jiménez, Carlos; Hernández, Domingo (Oxford University Press, 2023)

  Background: Immunoglobulin A nephropathy (IgAN) is the most frequent recurrent disease in kidney transplant recipients and its recurrence contributes to reducing graft survival. Several variables at the time of recurrence ...
• Factors associated with disease progression in patients with atrial fibrillation and heart failure anticoagulated with rivaroxaban

  Manito Lorite, Nicolás; Cepeda Rodrigo, José María; Farré López, Núria; Castillo Orive, Miguel; Galve, Enrique; Jiménez Candil, Javier; García Pinilla, José M.; López Sánchez, Eduardo Sebastián; Rafols, Carles; Gómez Doblas, Juan José (Wiley, 2024)

  Background: Patients with atrial fibrillation (AF) and heart failure (HF) have a high risk of thromboembolism and other outcomes and anticoagulation is recommended. Hypothesis: This study was aimed to explore the risk ...
• Comparative effectiveness of new treatment modalities for localized prostate cancer through patient-reported outcome measures

  Zamora, Víctor; Garin Boronat, Olatz, 1979-; Suárez, José Francisco; Gutiérrez, Cristina; Guedea, Ferrán; Cabrera, Patricia; Castells Esteve, Manel; Herruzo, Ismael; Fumadó Ciutat, Lluis; Samper, Pilar; Ferrer, Carlos; Regis, Lucas; Pont Acuña, Àngels; Ferrer Forés, Maria Montserrat; Multicentric Spanish Group of Clinically Localized Prostate Cancer (Elsevier, 2023)

  Purpose: There is scarce comparative effectiveness research on the new treatment modalities for localized prostate cancer. We aim to compare through Patient-Reported Outcome Measures (PROMs) the impact of active surveillance, ...
• A global perspective on stepping down chronic spontaneous urticaria treatment: Results of the Urticaria Centers of Reference and Excellence SDown-CSU study

  Türk, Murat; Kocatürk, Emek; Ertas, Ragip; Ensina, Luis Felipe; Ferrucci, Silvia M.; Grattan, Clive; Vestergaard, Christian; Zuberbier, Torsten; Maurer, Marcus; Giménez Arnau, Anna Maria (Wiley, 2024)

  Background: Although there have been significant advances in the treatment of chronic spontaneous urticaria (CSU) in recent years, there remains a lack of clear guidance on when and how to step down treatment in responders. ...
• Update on the management of older patients with pancreatic adenocarcinoma: a perspective from medical oncology

  Guillot Morales, Mónica; Visa Turmo, Laura; Brozos Vázquez, Elena; Feliu Batlle, Jaime; Khosravi Shahi, Parham; Laquente Sáez, Berta; López de San Vicente Hernández, Borja; Macarulla, Teresa; Gironés i Sarrió, Regina (Springer, 2024)

  In the context of pancreatic cancer, surgical intervention is typically recommended for localized tumours, whereas chemotherapy is the preferred approach in the advanced and/or metastatic setting. However, pancreatic cancer ...
• Minimal important difference of the 12-item World Health Organization Disability Assessment Schedule (WHODAS) 2.0 in persons with chronic low back pain

  Wong, Jessica J.; Hogg-Johnson, Sheilah; De Groote, Wouter; Cwirlej-Sozanska, Agnieszka; Garin Boronat, Olatz, 1979-; Ferrer Forés, Maria Montserrat; Pont Acuña, Àngels; Côté, Pierre (BioMed Central, 2023)

  Background: The World Health Organization Disability Assessment Schedule 2.0 12-item survey (WHODAS-12) is a questionnaire developed by the WHO to measure functioning across health conditions, cultures, and settings. ...
• NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy

  Hurtado Navarro, Laura; Bellosillo Paricio, Beatriz; García Ávila, Sara; Ferrer-Marín, Francisca (Elsevier, 2023)

  Chronic myelomonocytic leukemia (CMML) is frequently associated with mutations in the rat sarcoma gene (RAS), leading to worse prognosis. RAS mutations result in active RAS-GTP proteins, favoring myeloid cell proliferation ...
• Role of PATJ in stroke prognosis by modulating endothelial to mesenchymal transition through the Hippo/Notch/PI3K axis

  Medina Dols, Aina; Mola Caminal, Marina; Soriano Tarraga, Carolina; Giralt-Steinhauer, Eva; Lazcano Dobao, Uxue; Fernández-Pérez, Isabel; Jiménez-Balado, Joan; Jiménez Conde, Jordi; Vives Bauzá, Cristòfol (Nature Research, 2024)

  Through GWAS studies we identified PATJ associated with functional outcome after ischemic stroke (IS). The aim of this study was to determine PATJ role in brain endothelial cells (ECs) in the context of stroke outcome. ...
• Plasma metabolite profile of legume consumption and future risk of type 2 diabetes and cardiovascular disease

  Margara Escudero, Hernando J.; Castañer, Olga; Salas Salvadó, Jordi (BioMed Central, 2024)

  Background: Legume consumption has been linked to a reduced risk of type 2 diabetes (T2D) and cardiovascular disease (CVD), while the potential association between plasma metabolites associated with legume consumption and ...
• Trend and joinpoint analysis of cancer incidence and 1-Year mortality in north-east Spain 2005-2020

  Roura-Poch, Pere; Puigoriol, Emma; Altimiras, Jacint; Batiste Alentorn, Eduard; Dégano, Irene R. (MDPI, 2023)

  Cancer is the second leading cause of death. It is thus essential to examine cancer trends in all regions. In addition, trend data after 2019 and on cancer 1-year mortality are scarce. Our aim was to analyze incidence and ...
• The C250T mutation of TERTp might grant a better prognosis to glioblastoma by exerting less biological effect on telomeres and chromosomes than the C228T mutation

  Gorria, Teresa; Crous-Bou, Marta; Pineda, Estela; Hernandez, Ainhoa; Domenech, Marta; Sanz, Carolina; Jares, Pedro; Muñoz Mármol, Ana María; Arpí Llucià, Oriol; Meléndez, Bárbara; Gut, Marta; Esteve, Anna; Esteve-Codina, Anna; Parra Farré, Genís; Alameda Quitllet, Francisco; Carrato, Cristina; Aldecoa, Iban; Mallo, Mar; Iglesia, Nuria de la; Balana, Carmen (MDPI, 2024)

  The aim of this study was to determine how TERTp mutations impact glioblastoma prognosis. Materials and methods: TERTp mutations were assessed in a retrospective cohort of 258 uniformly treated glioblastoma patients. ...
• Cell-Free DNA as a biomarker at diagnosis and follow-up in 256 B and T-Cell lymphomas

  Díez-Feijóo, Ramón; Andrade-Campos, Marcio; Gibert Fernandez, Joan, 1988-; Sánchez González, Blanca; Fernández-Ibarrondo, Lierni; Fernández Rodríguez, M. Concepción; García Gisbert, Nieves, 1994-; Camacho Díaz, Laura; Lafuente, Marta; Vázquez, Ivonne; Colomo Saperas, Luis Alberto; Salar Silvestre, Antonio; Bellosillo Paricio, Beatriz (MDPI, 2024)

  Background: Cell-free DNA (cfDNA) analysis has become a promising tool for the diagnosis, prognosis, and monitoring of lymphoma cases. Until now, research in this area has mainly focused on aggressive lymphomas, with scanty ...
• Apalutamide for prostate cancer: Multicentre and multidisciplinary real-world study of 227 patients

  Córdoba Sánchez, Julián; Picola, Natàlia; Rodriguez-Vida, Alejo; Costa, Marc; Marmolejo Castañeda, David; Pérez Márquez, Meritxell; Muñoz Rodriguez, Jesús; Gaya Sopena, Josep Maria; Bravo, Alejandra; Buisan, Oscar; Servian, Pol; Suárez Novo, José Francisco; Musquera Felip, Mireia; Ribal Caparrós, Maria Jose; Alcaraz Asensio, Antonio; Vilaseca, Antoni (Wiley, 2023)

  Objective: To evaluate the efficacy and safety of apalutamide prostate cancer compared to the pivotal trials patients and to identify the first subsequent therapy in a real-world setting. Methods: The study is prospective ...

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