• Analyzing the role of cancer-associated fibroblast activation on macrophage polarization

  Bruch Oms, Marina; Olivera-Salguero, Rubén, 1991-; Mazzolini, Rocco; Valle Pérez, Beatriz del; Mayo González, Paula; Beteta, Ángel; Peña Arranz, Raúl; García de Herreros, Antonio (Wiley, 2023)

  Snail1 is a transcriptional factor required for cancer-associated fibroblast (CAF) activation, and mainly detected in CAFs in human tumors. In the mouse mammary tumor virus-polyoma middle tumor-antigen (MMTV-PyMT) model ...
• Which outcomes should be measured in hand eczema trials? Results from patient interviews and an expert survey

  Rönsch, Henriette; Schiffers, Frederike; Ofenloch, Robert; Weisshaar, Elke; Buse, Anna-Sophie; Hansen, Andreas; John, Swen Malte; Giménez Arnau, Anna Maria; Pesqué, David; Agner, Tove; Nørreslet, Line Brok; Loman, Laura; Romeijn, Geertruida L. E.; Schuttelaar, Marie-Louise A.; Košćec Bjelajac, Adrijana; Macan, Jelena; Bauer, Andrea; Apfelbacher, Christian J. (Wiley, 2023)

  Background: Hand eczema (HE) is a common skin disease characterized by itch, pain and visible skin changes such as fissures, erythema and vesicles. It is not yet clear which outcome domains are most important for patients. ...
• First experience of wave speed guided point-by-point cavo-tricuspid isthmus ablation for typical atrial flutter

  Vallès, Ermengol; Jiménez, Jesús; González, Carlos; Zaraket, Fatima; Rodríguez, Oriol; Llorca, Laia; Anguera, Ignasi; di Marco, Andrea; Fan, Roger; Casteigt, Benjamin (Springer, 2023)
• Why a complete response is the treatment aim in chronic spontaneous urticaria

  Bernstein, Jonathan A.; Giménez Arnau, Anna Maria; Maurer, Marcus; Staubach, Petra; Barbier, Nathalie; Hua, Eva; Severin, Thomas; Laires, Pedro A.; Balp, Maria Magdalena (MDPI, 2023)

  This study investigated the association between urticaria activity and health-related quality of life (HRQoL). Patient evaluations from the ligelizumab Phase 2b clinical trial (N = 382) were pooled (NCT02477332). Daily ...
• Why has epidemiology not (yet) succeeded in identifying the origin of the asthma epidemic?

  Antó i Boqué, Josep Maria; Pearce, Neil E.; Douwes, Jeroen; García Aymerich, Judith; Pembrey, Lucy; Richiardi, Lorenzo; Sunyer Deu, Jordi (Oxford University Press, 2023)
• Protein supplementation in a prehabilitation program in patients undergoing surgery for endometrial cancer

  Sole-Sedeno, Josep M.; Miralpeix, Ester; Muns, Maria Dolors; Rodriguez-Cosmen, Cristina; Fabregó, Berta; Kanjou, Nadwa; Medina, Francesc-Xavier; Mancebo Moreno, Gemma (MDPI, 2023)

  Enhanced recovery after surgery (ERAS) and prehabilitation programs are multidisciplinary care pathways to reduce stress response and improve perioperative outcomes, which also include nutritional interventions. The aim ...
• Association between malnutrition assessed by the global leadership initiative on malnutrition criteria and mortality in older people: a scoping review

  Sánchez-Rodríguez, María Dolores; De Meester, Dorien; Minon, Léa; Claessens, Marie; Gümüs, Neslian; Lieten, Siddhartha; Benoit, Florence; Surquin, Murielle; Marco Navarro, Ester (MDPI, 2023)

  The Global Leadership Initiative on Malnutrition (GLIM) criteria were introduced in 2018 for the diagnosis of malnutrition in adults. This review was aimed at gathering the evidence about the association between malnutrition ...
• A qualitative exploration of patient safety in a hospital setting in Spain: policy and practice recommendations on patients' and companions' participation

  Abiétar, Daniel G.; Domingo, Laia; Medina Perucha, Laura; Saavedra, Nuria; Berenguera, Anna; Lacueva-Pérez, Laia; Hurtado, Marta; Castells, Xavier; Sala, Maria (Wiley, 2023)

  Introduction: Patients' and companions' participation in healthcare could help prevent adverse events, which are a significant cause of disease and disability. Before designing interventions to increase participation, it ...
• Characterising the treatment of thromboembolic events after COVID-19 vaccination in 4 European countries and the US: an international network cohort study

  Markus, Aniek F.; Strauss, Victoria Y.; Burn, Edward; Li, Xintong; Delmestri, Antonella; Reich, Christian; Yin, Can; Mayer, Miguel Ángel, 1960-; Ramírez Anguita, Juan Manuel; Marti, Edelmira; Verhamme, Katia M. C.; Rijnbeek, Peter; Prieto-Alhambra, Daniel; Jödicke, Annika M. (Frontiers, 2023)

  Background: Thrombosis with thrombocytopenia syndrome (TTS) has been identified as a rare adverse event following some COVID-19 vaccines. Various guidelines have been issued on the treatment of TTS. We aimed to characterize ...
• Changes in bone quality after switching from a TDF to a TAF based ART: a pilot randomized study

  Soldado-Folgado, Jade; Rins-Lozano, Oriol; Arrieta Aldea, Itziar; González Mena, Alicia; Cañas-Ruano, Esperanza; Knobel Freud, Hernando; Garcia Giralt, Natàlia (Frontiers, 2023)

  Background: The impact of tenofovir disoproxil fumarate (TDF) antiretroviral (ART) regimens on bone health has been characterized mostly by bone mineral density (BMD), but recently also by bone quality (BQ). The aim of ...
• Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and partial rescue by risperidone

  Delgado-Sallent, Cristina; Gener, Thomas; Nebot Forcada, Pau; López-Cabezón, Cristina; Puig, M. Victoria (Frontiers, 2023)

  N-methyl D-aspartate receptor (NMDAR) hypofunction is a pathophysiological mechanism relevant for schizophrenia. Acute administration of the NMDAR antagonist phencyclidine (PCP) induces psychosis in patients and animals ...
• The natural history of QTc interval and its clinical impact in coronavirus disease 2019 survivors after 1 year

  Mojón Álvarez, Diana; Izquierdo, Andrea; Cubero Gallego, Héctor; Calvo-Fernández, Alicia; Marrugat de la Iglesia, Jaume; Pérez-Fernández, Silvia; Cabero, Paula; Solà-Richarte, Clàudia; Soler, Cristina; Farré López, Núria; Vaquerizo Montilla, Beatriz (Frontiers, 2023)

  Background and objective: Prolonged QTc interval on admission and a higher risk of death in SARS-CoV-2 patients have been reported. The long-term clinical impact of prolonged QTc interval is unknown. This study examined ...
• Comparison of Rotterdam and Barcelona magnetic resonance imaging risk calculators for predicting clinically significant prostate cancer

  Morote, Juan; Borque-Fernando, Ángel; Triquell, Marina; Campistol, Miriam; Servian, Pol; Abascal-Junquera, José María; Planas, Jacques; Méndez, Olga; Esteban, Luis M.; Trilla, Enrique (Elsevier, 2023)

  Background: Magnetic resonance imaging (MRI)-based risk calculators (MRI-RCs) individualise the likelihood of clinically significant prostate cancer (csPCa) and improve candidate selection for prostate biopsy beyond the ...
• Higher lymphocyte count associated with larger hippocampal volume and fewer depressive symptoms in drug–naïve first-episode psychosis

  Toll Privat, Alba; Blanco-Hinojo, Laura; Berge Baquero, Daniel; Martín-Subero, Marta; Casanovas, Francesc; El-Abidi, Khadija; Pérez Solá, Victor; Mané Santacana, Anna (Elsevier, 2023)

  Circulating white blood cells (leucocytes), which form the peripheral immune system, are crucial in inflammatory processes but their role in brain structural change in schizophrenia has been scarcely studied. With this ...
• STereotactic Arrhythmia Radioablation (STAR): the standardized treatment and outcome platform for stereotactic therapy of re-entrant tachycardia by a multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

  Grehn, Melanie; Algara López, Manuel-Ignacio; Martí-Almor, Julio; Verhoeff, Joost J. C. (Oxford University Press, 2023)

  The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research ...
• Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation

  Fuertes, Guillem; Valle Pérez, Beatriz del; Pastor Ruiz, Javier; Andrades, Evelyn; Peña Arranz, Raúl; García de Herreros, Antonio; Duñach, Mireia (EMBO Press, 2023)

  Colon tumors of the mesenchymal subtype have the lowest overall survival. Snail1 is essential for the acquisition of this phenotype, characterized by increased tumor stemness and invasion, and high resistance to chemotherapy. ...
• Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?

  Baeza, Immaculada; Serna, Elena de la; Mezquida, Gisela; Cuesta, Manuel J.; Vieta, Eduard; Amoretti, Silvia; Lobo, Antonio; González-Pinto, Ana; Díaz-Caneja, Covadonga M.; Corripio, Iluminada; Valli, Isabel; Puig, Olga; Mané Santacana, Anna; Bioque, Miquel; Ayora, Miriam; Bernardo, Miquel; Castro-Fornieles, Josefina; PEPs Group (Springer, 2023)

  To assess the role of age (early onset psychosis-EOP < 18 years vs. adult onset psychosis-AOP) and diagnosis (schizophrenia spectrum disorders-SSD vs. bipolar disorders-BD) on the duration of untreated psychosis (DUP) and ...
• Evidence for the effectiveness of interventions to reduce mental health related stigma in the workplace: a systematic review

  Tóth, Mónika Ditta; Ihionvien, Sarah; Leduc, Caleb; Aust, Birgit; Amann, Benedikt Lorenz; Cresswell-Smith, Johanna; Reich, Hanna; Cully, Grace; Sanches, Sarita; Fanaj, Naim; Qirjako, Gentiana; Tsantila, Fotini; Ross, Victoria; Mathieu, Sharna; Pashoja, Arlinda Cerga; Arensman, Ella; Purebl, György; MENTUPP consortium members (BMJ Publishing Group, 2023)

  Objectives: Increasing access to mental health support is a key factor for treating mental disorders, however, important barriers complicate help-seeking, among them, mental health related stigma being most prominent. We ...
• Fracture risk reduction and safety by osteoporosis treatment compared with placebo or active comparator in postmenopausal women: systematic review, network meta-analysis, and meta-regression analysis of randomised clinical trials

  Händel, Mina Nicole; Nogués Solan, Francesc Xavier; Abrahamsen, Bo (BMJ Publishing Group, 2023)

  Objective: To review the comparative effectiveness of osteoporosis treatments, including the bone anabolic agents, abaloparatide and romosozumab, on reducing the risk of fractures in postmenopausal women, and to characterise ...
• Assessing the implementation of nurse practitioner-led huddles in long-term care using the Consolidated Framework for Implementation Research (CFIR)

  Wills, Aria; Krassikova, Alexandra; Keatings, Margaret; Escrig-Piñol, Astrid; Bethell, Jennifer; McGilton, Katherine S. (Springer, 2023)

  Background: The COVID-19 pandemic created major challenges in long-term care (LTC) homes across Canada and globally. A nurse practitioner-led interdisciplinary huddle intervention was developed to support staff wellbeing ...

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