• Population-based multicase-control study in common tumors in Spain (MCC-Spain): rationale and study design

  Castano-Vinyals, Gemma; Aragonés, Núria; Pérez-Gómez, Beatriz; Martín, Vicente; Llorca, Javier; Moreno, Víctor; Altzibar, Jone Miren; Ardanaz, Eva; Sanjosé Llongueras, Silvia de; Jiménez-Moleón, José Juan; Tardón, Adonina; Alguacil, Juan; Peiró, Rosana; Marcos-Gragera, Rafael; Navarro, Carmen; Pollán, Marina; Kogevinas, Manolis; MCC-Spain Study Group (Elsevier, 2015)

  Introduction. We present the protocol of a large population-based case-control study of 5 common tumors in Spain (MCC-Spain) that evaluates environmental exposures and genetic factors. Methods. Between 2008-2013, 10,183 ...
• Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts

  Casas Sanahuja, Maribel; Martínez, David; Kogevinas, Manolis; García, Ana María; Nieuwenhuijsen, Mark J.; Vrijheid, Martine (NOROSH, 2015)

  Objectives. We assessed whether maternal employment during pregnancy – overall and in selected occupational sectors – is associated with birth weight, small for gestational age (SGA), term low birth weight (LBW), length ...
• Cardiovascular risk protection from the Mediterranean diet and olive oil: a transcriptomic update in humans

  Carrión, Sílvia; Torres-Collado, Laura; Castañer, Olga (CSIC, 2016)

  This review highlights the human studies that explore the benefits of the Mediterranean diet and olive oil, based on gene expression analysis. We summarized consistent human transcriptomic studies on cardiovascular risk, ...
• Validación de la versión española: expectativa y conocimiento recibido del paciente hospitalizado

  Cano-Plazas, Sara; Lacueva-Pérez, Laia; Cabrera Torres, Esther; Zabalegui, Adelaida (Universidad de La Sabana - Palabra clave, 2017)

  Objetivo: evaluar la validez y la fiabilidad de la versión española del instrumento Expectativas y conocimiento recibido del paciente hospitalizado (ECPH/CRPH) en pacientes con osteoartritis intervenidos de artroplastia ...
• The acute effects of ultraviolet radiation on the blood transcriptome are independent

  Bustamante Pineda, Mariona; Hernandez-Ferrer, Carles, 1987-; Sarria-Trujillo, Yaris; Harrison, Graham I.; Nonell Mazelón, Lara; Kang, Wenjing; Friedländer, Marc R.; Estivill, Xavier, 1955-; González, Juan Ramón; Nieuwenhuijsen, Mark J.; Young, Antony R. (Elsevier, 2017)

  The molecular basis of many health outcomes attributed to solar ultraviolet radiation (UVR) is unknown. We tested the hypothesis that they may originate from transcriptional changes in blood cells. This was determined by ...
• Early life tobacco exposure and children's telomere length: The HELIX project

  Osorio Yáñez, Citlalli; Clemente Batalha Pardal, Diana, 1990-; Maitre, Léa; Vives Usano, Marta, 1990-; Bustamante Pineda, Mariona; Martínez, David; Casas Sanahuja, Maribel; Urquiza, José M.; Tamayo-Uria, Ibon; Sunyer Deu, Jordi; Vrijheid, Martine (Elsevier, 2020)

  Telomere length and mitochondrial DNA content are considered biomarkers of cellular aging, oxidative stress, and inflammation, but there is almost no information on their association with tobacco smoke exposure in fetal ...
• Interaction between airborne copper exposure and ATP7B polymorphisms on inattentiveness in scholar children

  Alemany, Silvia; Vilor-Tejedor, Natàlia; Bustamante Pineda, Mariona; Álvarez Pedrerol, Mar, 1981-; Rivas, Ioar; Forns i Guzman, Joan, 1981-; Querol, Xavier; Pujol Martí, Jesús, 1981-; Sunyer Deu, Jordi (Elsevier, 2017)

  Recent research indicates that airborne copper exposure in scholar children negatively affects brain functioning. These effects are likely to be influenced by the efficiency of copper metabolism, which is partly regulated ...
• Cortical structures associated with sports participation in children: a population-based study

  López Vicente, Mònica, 1988-; Tiemeier, Henning; Wildeboer, Andrea; Muetzel, Ryan L.; Verhulst, Frank C.; Jaddoe, Vincent W.V.; Sunyer Deu, Jordi; White, Tonya (Taylor & Francis, 2017)

  We studied cortical morphology in relation to sports participation and type of sport using a large sample of healthy children (n = 911). Sports participation data was collected through a parent-reported questionnaire. ...
• Increased risk of asthma in overweight children born large for gestational age

  Pinto, Leonardo A.; Guerra, Stefano; Antó i Boqué, Josep Maria; Postma, Dirkje S.; Koppelman, Gerard H.; Jongste, Johan C. de; Gehring, Ulrike; Smit, Henriëtte A.; Wijga, Alet (Wiley, 2017)

  Background: Being born large for gestational age (LGA) is a marker of increased growth velocity in fetal life and a risk factor for childhood overweight. Both being born LGA and childhood overweight may influence the ...
• Value of shared preclinical safety studies – The eTOX database

  Briggs, Katharine; Barber, Chris; Cases, Montserrat; Marc, Philippe; Steger-Hartmann, Thomas (Elsevier, 2015)

  A first analysis of a database of shared preclinical safety data for 1214 small molecule drugs and drug candidates extracted from 3970 reports donated by thirteen pharmaceutical companies for the eTOX project (www.etoxproject.eu) ...
• Sleeping, TV, cognitively stimulating activities, physical activity, and attention-deficit hyperactivity disorder symptom incidence in children: a prospective study

  Peralta, Gabriela P.; Forns i Guzman, Joan, 1981-; García de la Hera, Manuela; González, Llúcia; Guxens Junyent, Mònica; López Vicente, Mònica, 1988-; Sunyer Deu, Jordi; García Aymerich, Judith (Lippincott Williams & Wilkins, 2018)

  Objective: To analyze associations between time spent sleeping, watching TV, engaging in cognitively stimulating activities, and engaging in physical activity, all at 4 years, and (1) attention-deficit/hyperactivity disorder ...
• Maternal thyroid function in early pregnancy and child attention-deficit hyperactivity disorder: an individual-participant meta-analysis

  Levie, Deborah; Korevaar, Tim I. M.; Mulder, Tessa A.; Bath, Sarah C.; Dineva, Mariana; Lopez-Espinosa, Maria-José; Basterrechea, Mikel; Santa Marina, Loreto; Rebagliato, Marisa; Sunyer Deu, Jordi; Rayman, Margaret P.; Tiemeier, Henning; Peeters, Robin P.; Guxens Junyent, Mònica (Mary Ann Liebert, Inc, 2019)

  Background: Thyroid hormone is essential for optimal fetal brain development. Evidence suggests that both low and high maternal thyroid hormone availability may have adverse effects on child neurodevelopmental outcomes, ...
• Identification of technical problems affecting performance of DustTrak DRX aerosol monitors

  Rivas, Ioar; Mazaheri, Mandana; Viana, Mar; Moreno, Teresa; Clifford, Samuel; He, Congrong; Bischof, Oliver F.; Martins, Vânia; Reche, Cristina; Alastuey, Andrés; Álvarez Pedrerol, Mar, 1981-; Sunyer Deu, Jordi; Morawska, Lidia; Querol, Xavier (Elsevier, 2017)

  The TSI DustTrak Aerosol Monitor is a portable real-time instrument widely used for particulate matter (PM) mass concentrations monitoring. The aim of this work is to report on issues that have arisen from the use of the ...
• Health equity and burden of childhood asthma - related to air pollution in Barcelona

  Pierangeli, Ilaria; Nieuwenhuijsen, Mark J.; Cirach, Marta; Rojas Rueda, David, 1979- (Elsevier, 2020)

  Background: Air pollution is one of the major health risk factors in urban populations. Air pollution has been associated with asthma in children. Air pollution has also been suggested to be distributed unequally within ...
• Health impacts of bike sharing systems in Europe

  Otero Hernández, Isabel; Nieuwenhuijsen, Mark J.; Rojas Rueda, David, 1979- (Elsevier, 2018)

  Background: Bike-sharing systems (BSS) have been implemented in several cities around the world as policies to mitigate climate change, reduce traffic congestion, and promote physical activity. This study aims to assess ...
• Creatine kinase is decreased in childhood asthma

  Guerra, Stefano; Lavi, Iris; Carsin, Anne-Elie; Vidal, Marta; Bustamante Pineda, Mariona; García Aymerich, Judith; Dobaño, Carlota; Kogevinas, Manolis; Sunyer Deu, Jordi; Antó i Boqué, Josep Maria (American Thoracic Society, 2023)

  Rationale: The identification of novel molecules associated with asthma may provide insights into the mechanisms of disease and their potential clinical implications. Objectives: To conduct a screening of circulating ...
• Roles of the physical environment in health-related quality of life in patients with chronic obstructive pulmonary disease

  Moitra, Subhabrata; Foraster Pulido, Maria, 1984-; Arbillaga Etxarri, Ane, 1986-; Marín, Alicia; Barberan-Garcia, Anael; Rodríguez Chiaradia, Diego Agustín; Balcells Vilarnau, Eva, 1967-; Koreny, Maria, 1972-; Torán-Monserrat, Pere; Vall-Casas, Pere; Rodríguez Roisin, Robert; García Aymerich, Judith (Elsevier, 2022)

  Rationale: Many clinical and psychological factors are known to influence the health-related quality of life (HRQL) in chronic obstructive pulmonary disease (COPD). However, research on whether environmental factors, such ...
• Early-childhood BMI trajectories in relation to preclinical cardiovascular measurements in adolescence

  Montazeri, Parisa, 1988-; Fossati, Serena; Clemente Batalha Pardal, Diana, 1990-; Cirugeda, Lourdes; Elosua Llanos, Roberto; Fernández-Barrés, Sílvia; Fochs, Silvia; Garcia-Esteban, Raquel; Marquez, Sandra; Pey, Núria; Nawrot, Tim S.; Vrijheid, Martine (Cambridge University Press, 2022)

  Cardiovascular diseases are the leading causes of morbidity and mortality. Overweight, obesity, and accelerated growth during early childhood have been associated with adverse cardiovascular outcomes in later life. Few ...
• Consumption of ultra-processed foods and drinks and colorectal, breast, and prostate cancer

  Romaguera Bosch, Dora; Fernández-Barrés, Sílvia; Gracia-Lavedán, Esther; Castaño Vinyals, Gemma; Kogevinas, Manolis; Amiano, Pilar (Elsevier, 2021)

  Aims: To study whether the consumption of ultra-processed foods and drinks is associated with breast, colorectal, and prostate cancers. Methods: Multicentric population-based case-control study (MCC-Spain) conducted in 12 ...
• Integrating mechanistic and toxicokinetic information in predictive models of cholestasis

  Rodríguez-Belenguer, Pablo; Mangas Sanjuan, Victor; Soria Olivas, Emilio; Pastor Maeso, Manuel (American Chemical Society (ACS), 2023)

  Drug development involves the thorough assessment of the candidate's safety and efficacy. In silico toxicology (IST) methods can contribute to the assessment, complementing in vitro and in vivo experimental methods, since ...

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