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Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM))

Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM))

 

Recent Submissions

  • Maurer, Marcus; Giménez Arnau, Anna Maria; Castaldo, Anthony (Wiley-Blackwell, 2020)
  • Carrillo-Reixach, Juan; Arnal, Magdalena; Nonell Mazelón, Lara; Armengol, Carolina (Elsevier, 2020)
    Background & aims: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the ...
  • Martín Sánchez, Ana; Piñero González, Janet, 1977-; Nonell Mazelón, Lara; Arnal, Magdalena; Ribe, Elena; Nevado-Holgado, Alejo J.; Lovestone, Simon; Sanz, Ferran; Furlong, Laura I., 1971-; Valverde, Olga (BioMed Central, 2021)
    Background: Major depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer's disease (AD). Despite both diseases having a robust genetic component, ...
  • Chadban, Steven J.; Pascual Santos, Julio; Knoll, Gregory A. (Wolters Kluwer (LWW), 2020)
    The 2020 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation is intended to assist health care professionals worldwide who ...
  • Silvestre Salvador, Juan Francisco; Heras-Mendaza, Felipe; Hervella Garcés, Marcos; Palacios-Martínez, D.; Sánchez Camacho, R.; Senan Sanz, R.; Apellaniz González, A.; Giménez Arnau, Anna Maria (Elsevier, 2020)
    El eccema de manos es una patología frecuente con un fuerte impacto en la calidad de vida de los pacientes y un alto coste social y laboral. Su manejo por los médicos de atención primaria y de medicina del trabajo es ...
  • Cacciaglia, Raffaele; Molinuevo, José Luis; Falcón, Carles; Arenaza Urquijo, Eider M.; Sánchez Benavides, Gonzalo; Brugulat Serrat, Anna, 1986-; Blennow, Kaj; Zetterberg, Henrik; Gispert López, Juan Domingo; ALFA study (Oxford University Press, 2020)
    Gray matter networks (GMn) provide essential information on the intrinsic organization of the brain and appear to be disrupted in Alzheimer's disease (AD). Apolipoprotein E (APOE)-ε4 represents the major genetic risk factor ...
  • Gallego-Fabrega, Cristina; Cullell, Natalia; Soriano Tarraga, Carolina; Carrera, Caty; Torres-Aguila, Nuria P.; Muiño, Elena; Cárcel-Márquez, Jara; Castro de Moura, Manuel; Fernández Sanlés, Alba; Esteller, Manel; Elosua Llanos, Roberto; Jiménez Conde, Jordi; Roquer, Jaume; Montaner, Joan; Krupinski, Jerzy; Fernández-Cadenas, Israel (Impact Journals, 2020)
    Background and purpose: Polymorphisms and serum levels of Matrix Metalloproteinases (MMP) and Tissue Inhibitor of Metalloproteinases (TIMP) have been studied with regard to atheromatous plaques and ischemic stroke, while ...
  • Gómez-Martín, Ignacio; Collgros, Helena; Ferguson, Peter M.; Barreiro, Alicia; Guitera, Pascale; Andrades, Evelyn; Puig, Susana; Pujol Vallverdú, Ramon Maria; Barranco Sanz, Luis Carlos; Alòs, Llúcia; Segura Tigell, Sonia (Elsevier, 2020)
    Background: Pigmented labial macules (PLMs) are clinical, dermoscopic, and histopathologic challenges. Objective: To describe and evaluate the utility of reflectance confocal microscopy (RCM) in PLMs and to establish a ...
  • Porcheri, Cristina; Golan, Ohad; Calero-Nieto, Fernando J.; Thambyrajah, Roshana; Ruiz-Herguido, Cristina; Wang, Xiaonan; Catto, Francesca; Guillén, Yolanda; Sinha, Roshani; González, Jessica; Kinston, Sarah J.; Mariani, Samanta A.; Maglitto, Antonio; Vink, Chris S.; Dzierzak, Elaine; Charbord, Pierre; Göttgens, Bertie; Espinosa Blay, Lluís; Sprinzak, David; Bigas Salvans, Anna (Wiley-Blackwell, 2020)
    Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium in cluster structures that protrude into the embryonic aortic lumen. Although much is known about the molecular characteristics of the developing ...
  • Leisman, Daniel E.; Barreiro Portela, Esther; Maslove, David M.; Prediction models aim to use available data to predict a health state or outcome that has not yet been observed. Prediction is primarily relevant to clinical practice, but is also used in research, and administration. While prediction modeling involves estimating the relationship between patient factors and outcomes, it is distinct from casual inference. Prediction modeling thus requires unique considerations for development, validation, and updating. This document represents an effort from editors at 31 respiratory, sleep, and critical care medicine journals to consolidate contemporary best practices and recommendations related to prediction study design, conduct, and reporting. Herein, we address issues commonly encountered in submissions to our various journals. Key topics include considerations for selecting predictor variables, operationalizing variables, dealing with missing data, the importance of appropriate validation, model performance measures and their interpretation, and good reporting practices. Supplemental discussion covers emerging topics such as model fairness, competing risks, pitfalls of "modifiable risk factors", measurement error, and risk for bias. This guidance is not meant to be overly prescriptive; we acknowledge that every study is different, and no set of rules will fit all cases. Additional best practices can be found in the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) guidelines, to which we refer readers for further details. (Wolters Kluwer (LWW), 2020)
  • Alías Ferri, María; García-Marchena, Nuria; Mestre-Pintó, Juan Ignacio; Araos, Pedro; Vergara-Moragues, Esperanza; Fonseca Casals, Francina, 1972-; González-Saiz, Francisco; Rodríguez de Fonseca, Fernando; Torrens, Marta; The NEURODEP Group (Socidrogalcohol, 2020)
    Antecedentes: El consumo de cocaína es un creciente problema de salud en todo el mundo. Además, los pacientes con trastorno por consumo de cocaína (TCC) presentan una alta comorbilidad con el trastorno depresivo mayor ...
  • López-Castillo, Daniel; March-Rodríguez, Alvaro; Rodriguez-Vida, Alejo; Pujol Vallverdú, Ramon Maria; Segura Tigell, Sonia (Society for Publication of Acta Dermato-Venereologica, 2020)
  • Ortiz-Romero, Pablo L.; Servitje, Octavio; Estrach, Teresa; Izu-Belloso, Rosa María; Fernández-de-Misa, Ricardo; Gallardo Hernández, Fernando; López-Martínez, Noemí; Pérez-Mitru, Alejandro (Dove Medical Press, 2020)
    Aim: To identify the most common therapeutic options for the treatment of early-stage mycosis fungoides in Spain, quantify their associated healthcare resource use and costs. Methods: After reviewing the literature, a panel ...
  • Salvadó, Gemma; Grothe, Michel J.; Groot, Colin; Moscoso, Alexis; Schöll, Michael; Gispert López, Juan Domingo; Ossenkoppele, Rik; Alzheimer’s Disease Neuroimaging Initiative (Springer, 2021)
    Purpose: To examine associations between the APOE-ε2 and APOE-ε4 alleles and core Alzheimer's disease (AD) pathological hallmarks as measured by amyloid-β (Aβ) and tau PET in older individuals without dementia. Methods: ...
  • Moreno, Gerard; Rodríguez, Alejandro; Sole-Violán, Jordi; Martín Loeches, Ignacio; Díaz, Emili; Bodí, María; Reyes, Luis F.; Gómez, Josep; Guardiola, Juan; Trefler, Sandra; Vidaur, Loreto; Papiol, Elisabet; Socias, Lorenzo; García Vidal, Carolina; Correig, Eudald; Marín Corral, Judith; Restrepo, Marcos I.; Nguyen-Van-Tam, Jonathan S.; Torres, Antoni (UNLISTED PUBLISHER, 2021)
    Background: The relationship between early oseltamivir treatment (within 48 h of symptom onset) and mortality in patients admitted to intensive care units (ICUs) with severe influenza is disputed. This study aimed to ...
  • Baumgartner, Tobias; Rocamora Zúñiga, Rodrigo Alberto; Surges, Rainer (Wiley, 2021)
    Objective: Clinical care of rare and complex epilepsies is challenging, because evidence-based treatment guidelines are scarce, the experience of many physicians is limited, and interdisciplinary treatment of comorbidities ...
  • de Andrés-Nogales, Fernando; Casado, Miguel Angel; Trillo, José Luis; Ruiz-Moreno, José María; Martínez-Sesmero, José Manuel; Peralta, Gemma; Poveda, José Luis; Ortiz Sagrista, Pere; Ignacio, Emilio; Zarranz-Ventura, Javier; Udaondo, Patricia; Mur, Carlos; Álvarez, Eloísa; Cervera, Enrique; Martínez, Mercedes; Llorente, Iñaki; Zulueta, Jacinto; Rodríguez-Maqueda, Mariano; García-Layana, Alfredo; Martínez-Olmos, José (SpringerOpen, 2020)
    Background: The clinical and economic management of retinal diseases has become more complex following the introduction of new intravitreal treatments. Multicriteria decision analysis (MCDA) offers the potential to overcome ...
  • González-Corvillo, Carmen; Crespo Barrio, Marta; Gentil, Miguel Ángel (Wolters Kluwer (LWW), 2019)
    Background: Direct-acting antivirals (DAA) allow effective and safe eradication of hepatitis C virus (HCV) in most patients. There are limited data on the long-term effects of all-oral, interferon-free DAA combination ...
  • Vena, Antonio; Bouza, Emilio; Bassetti, Matteo; Menichetti, Francesco; Merelli, Maria; Grau Cerrato, Santiago; Aguado, José María; Merino, Paloma; Merino, Paloma; Bonache, Francisco; Muñoz, Patrícia (SpringerOpen, 2020)
    Introduction: To assess the association between exposure to micafungin, other echinocandins, or azoles and the development of short-term liver injury (STLI) or long-term liver injury (LTLI) in patients with Child-Pugh B ...
  • Ho, Janice Y.; Zijlema, Wilma; Triguero Mas, Margarita, 1985-; Donaire González, David; Valentín, Antònia; Ballester, Joan; Chan, Emily Y.Y.; Goggins, William B.; Mo, Phoenix K.H.; Kruize, Hanneke; Berg, Magdalena van den; Gražulevičienė, Regina; Gidlow, Christopher J.; Jerrett, Michael; Seto, Edmund; Barrera Gómez, Jose; Nieuwenhuijsen, Mark J. (Elsevier, 2021)
    Background: Physical activity can be affected by both meteorological conditions and surrounding greenness, but few studies have evaluated the effects of these environmental factors on physical activity simultaneously. This ...

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