• Effect of an intensive lifestyle intervention on the structural and functional substrate for atrial fibrillation in people with metabolic syndrome

  Rosselló, Xavier; Ramallal, Raúl; Romaguera Bosch, Dora; Alonso-Gómez, Ángel; Alonso, Álvaro; Tojal Sierra, Lucas; Fernández Palomeque, Carlos; Martínez-González, Miguel Ángel, 1957-; Garrido Uriarte, María; López Rodríguez, Luis; Díaz Dorronsoro, Agnes; Zaldua Irastorza, Olatz; Shah, Amit J.; Salas Salvadó, Jordi; Fitó Colomer, Montserrat; Toledo, Estefania (Oxford University Press, 2024)

  Aims: To evaluate the effect of an intensive lifestyle intervention (ILI) on the structural and functional cardiac substrate of atrial fibrillation (AF) in overweight or obese people with metabolic syndrome (Mets). Methods ...
• Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial

  Murcia Lesmes, David; Pérez-Vega, Karla Alejandra; Lamuela-Raventós, Rosa M. (Oxford University Press, 2024)

  Aims: Clinical studies have produced conflicting evidence on the effects of the consumption of tomatoes on blood pressure, and there are limited data from epidemiologic studies. This study assesses whether tomato consumption ...
• Impact of simulated reduced injected dose on the assessment of amyloid PET scans

  Young, Peter; Heeman, Fiona; Axelsson, Jan; Collij, Lyduine E.; Hitzel, Anne; Sanaat, Amirhossein; Niñerola-Baizán, Aida; Perissinotti, Andrés; Lubberink, Mark; Frisoni, Giovanni B.; Zaidi, Habib; Barkhof, Frederik; Farrar, Gill; Baker, Suzanne; Gispert López, Juan Domingo; Garibotto, Valentina; Rieckmann, Anna; Schöll, Michael; AMYPAD Consortium (Springer, 2024)

  Purpose: To investigate the impact of reduced injected doses on the quantitative and qualitative assessment of the amyloid PET tracers [18F]flutemetamol and [18F]florbetaben. Methods: Cognitively impaired and unimpaired ...
• Safety profile of pembrolizumab monotherapy based on an aggregate safety evaluation of 8937 patients

  Brahmer, Julie R.; Bellmunt Molins, Joaquim, 1959-; Ribas, Antoni (Elsevier, 2024)

  Background: Pembrolizumab has a manageable safety profile as described in its label, which was primarily based on 2799 patients who participated in clinical trials for melanoma or non-small cell lung cancer. Here, we ...
• Prognostic factors of progressive fibrotic hypersensitivity pneumonitis: a large, retrospective, multicentre, observational cohort study

  Cano Jiménez, Esteban; Villar Gómez, Ana; Velez Segovia, Eduardo; Aburto Barrenechea, Myriam; Sellarés, Jacobo; Francesqui, Joel; Portillo, Karina; Solis Solis, Alan Jhunior; Acosta Fernández, Orlando; Llanos González, Ana Belén; Bordas Martínez, Jaume; Cabrera César, Eva; Balcells Vilarnau, Eva, 1967-; Castillo, Diego; Reyes Pardessus, Ana; González Fernández, Coral; García Moyano, Marta; Urrutia Gajate, Amaia; Blanco Hortas, Andrés; Molina-Molina, María (European Respiratory Society, 2024)

  Background: Fibrotic hypersensitivity pneumonitis (fHP) is an immune-mediated interstitial lung disease caused by sensitisation to chronic allergen inhalation. This study aimed to determine prognostic indicators of progression ...
• Overnight desaturation in interstitial lung diseases: links to pulmonary vasculopathy and mortality

  Margaritopoulos, George A.; Proklou, Athanasia; Trachalaki, Athina; Badenes Bonet, Diana, 1987-; Kokosi, Maria; Kouranos, Vasilis; Chua, Felix; George, Peter; Renzoni, Elisabetta A.; Devaraj, Anand; Desai, Sujal; Nicholson, Andrew G.; Antoniou, Katerina M.; Wells, Athol U. (European Respiratory Society, 2024)

  Background: Overnight desaturation predicts poor prognosis across interstitial lung diseases (ILDs). The aim of the present study was to investigate whether nocturnal desaturation is associated with pulmonary vasculopathy ...
• ERS International Congress 2023: highlights from the Pulmonary Vascular Diseases Assembly

  Cullivan, Sarah; Boucly, Athénaïs; Jevnikar, Mitja; Lechartier, Benoit; Ulrich, Silvia; Bertoletti, Laurent; Sitbon, Olivier; Vonk-Noordegraaf, Anton; Bokan, Aleksandar; Park, Da-Hee; Genecand, Leon; Guiot, Julien; Jutant, Etienne-Marie; Piccari, Lucilla; Lichtblau, Mona (European Respiratory Society, 2024)

  Pulmonary vascular diseases such as pulmonary embolism and pulmonary hypertension are important and frequently under-recognised conditions. This article provides an overview of key highlights in pulmonary vascular diseases ...
• Determination of well-being-related markers in nails by liquid chromatography tandem mass spectrometry

  Gómez-Gómez, Àlex; Montero-San Martin, Blanca; Haro, Noemí; Pozo Mendoza, Óscar J., 1975- (Elsevier, 2023)

  Well-being is a multifactorial positive state that is highly influenced by some endogenous molecules that control happiness and euphoric feelings. These molecules, e.g., neurotransmitters, hormones and their derivatives, ...
• Other malignancies in the history of CLL: an international multicenter study conducted by ERIC, the European Research Initiative on CLL, in HARMONY

  Chatzikonstantinou, Thomas; Gimeno Vázquez, Eva; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Stamatopoulos, Kostas (Elsevier, 2023)

  Background: Patients with chronic lymphocytic leukemia (CLL) have a higher risk of developing other malignancies (OMs) compared to the general population. However, the impact of CLL-related risk factors and CLL-directed ...
• Painful hemorrhage of vestibular papillae: A probably underreported complication of vestibular papillomatosis

  López Trujillo, Emilio; Segura Tigell, Sonia; Sánchez-Schmidt, Julia Maria (Mattioli 1885, 2024)
• Biomarker and pharmacodynamic activity of the transforming growth factor-beta (TGFβ) inhibitor SAR439459 as monotherapy and in combination with cemiplimab in a phase I clinical study in patients with advanced solid tumors

  Robbrecht, Debbie; Rodriguez-Vida, Alejo; Wang, Rui (Wiley, 2024)

  SAR439459, a 'second-generation' human anti-transforming growth factor-beta (TGFβ) monoclonal antibody, inhibits all TGFβ isoforms and improves the antitumor activity of anti-programmed cell death protein-1 therapeutics. ...
• Sensitization to textile dyes in Spain: Epidemiological situation (2019-2022)

  Hernández Fernández, Carlos Pelayo; Giménez Arnau, Anna Maria; García Doval, Ignacio (Wiley, 2024)

  Background: Current frequency and features for positivity to textile dye mix (TDM) in Spain are unknown. Objectives: To study the frequency, clinical features and simultaneous positivity between TDM, para-phenylenediamine ...
• A machine learning approach to identify groups of patients with hematological malignant disorders

  Rodríguez-Belenguer, Pablo; Piñana, José Luis; Sánchez Montañés, Manuel; Soria Olivas, Emilio; Martínez Sober, Marcelino; Serrano López, Antonio J. (Elsevier, 2024)

  Background and objective: Vaccination against SARS-CoV-2 in immunocompromised patients with hematologic malignancies (HM) is crucial to reduce the severity of COVID-19. Despite vaccination efforts, over a third of HM ...
• Exploratory analyses of treatment subgroup interaction by PD-L1 status and according to PD-L1 expression in the JAVELIN Bladder 100 trial

  Climent, Miguel Ángel; Álvarez, Carlos; Morales-Barrera, Rafael; Maroto, Pablo; Rodríguez-Vida, Alejo; Méndez-Vidal, María José; García del Muro, Xavier; Puente, Javier; Láinez, Nuria; Vázquez, Sergio; Castellano, Daniel; Gómez Lang, Carmen; Wang, Jing; Di Pietro, Alessandra; Davis, Craig; Sanz Castillo, Belén; Bolós, M. Victoria; Valderrama, Begoña P. (Springer, 2024)

  Purpose: Post hoc analysis of the JAVELIN Bladder 100 trial of avelumab maintenance in locally advanced/metastatic urothelial carcinoma (la/mUC) to determine the interaction by programmed death ligand 1 (PD-L1) status for ...
• Tubulo-interstitial inflammation increases the risk of graft loss after the recurrence of IgA nephropathy

  Rodrigo Calabia, Emilio; Quintana, Luis; Vázquez Sánchez, Teresa; Sánchez Fructuoso, Ana; Buxeda, Anna; Gavela, Eva; Cazorla, Juan M.; Cabello, Sheila; Beneyto, Maria Isabel; López-Oliva, Maria O.; Diekmann, Fritz; Gómez Ortega, José M.; Calvo Romero, Natividad; Pérez-Sáez, María José; Sancho, Asunción; Mazuecos, Auxiliadora; Espí Reig, Jordi; Jiménez, Carlos; Hernández, Domingo (Oxford University Press, 2023)

  Background: Immunoglobulin A nephropathy (IgAN) is the most frequent recurrent disease in kidney transplant recipients and its recurrence contributes to reducing graft survival. Several variables at the time of recurrence ...
• Factors associated with disease progression in patients with atrial fibrillation and heart failure anticoagulated with rivaroxaban

  Manito Lorite, Nicolás; Cepeda Rodrigo, José María; Farré López, Núria; Castillo Orive, Miguel; Galve, Enrique; Jiménez Candil, Javier; García Pinilla, José M.; López Sánchez, Eduardo Sebastián; Rafols, Carles; Gómez Doblas, Juan José (Wiley, 2024)

  Background: Patients with atrial fibrillation (AF) and heart failure (HF) have a high risk of thromboembolism and other outcomes and anticoagulation is recommended. Hypothesis: This study was aimed to explore the risk ...
• Comparative effectiveness of new treatment modalities for localized prostate cancer through patient-reported outcome measures

  Zamora, Víctor; Garin Boronat, Olatz, 1979-; Suárez, José Francisco; Gutiérrez, Cristina; Guedea, Ferrán; Cabrera, Patricia; Castells Esteve, Manel; Herruzo, Ismael; Fumadó Ciutat, Lluis; Samper, Pilar; Ferrer, Carlos; Regis, Lucas; Pont Acuña, Àngels; Ferrer Forés, Maria Montserrat; Multicentric Spanish Group of Clinically Localized Prostate Cancer (Elsevier, 2023)

  Purpose: There is scarce comparative effectiveness research on the new treatment modalities for localized prostate cancer. We aim to compare through Patient-Reported Outcome Measures (PROMs) the impact of active surveillance, ...
• A global perspective on stepping down chronic spontaneous urticaria treatment: Results of the Urticaria Centers of Reference and Excellence SDown-CSU study

  Türk, Murat; Kocatürk, Emek; Ertas, Ragip; Ensina, Luis Felipe; Ferrucci, Silvia M.; Grattan, Clive; Vestergaard, Christian; Zuberbier, Torsten; Maurer, Marcus; Giménez Arnau, Anna Maria (Wiley, 2024)

  Background: Although there have been significant advances in the treatment of chronic spontaneous urticaria (CSU) in recent years, there remains a lack of clear guidance on when and how to step down treatment in responders. ...
• Update on the management of older patients with pancreatic adenocarcinoma: a perspective from medical oncology

  Guillot Morales, Mónica; Visa Turmo, Laura; Brozos Vázquez, Elena; Feliu Batlle, Jaime; Khosravi Shahi, Parham; Laquente Sáez, Berta; López de San Vicente Hernández, Borja; Macarulla, Teresa; Gironés i Sarrió, Regina (Springer, 2024)

  In the context of pancreatic cancer, surgical intervention is typically recommended for localized tumours, whereas chemotherapy is the preferred approach in the advanced and/or metastatic setting. However, pancreatic cancer ...
• Minimal important difference of the 12-item World Health Organization Disability Assessment Schedule (WHODAS) 2.0 in persons with chronic low back pain

  Wong, Jessica J.; Hogg-Johnson, Sheilah; De Groote, Wouter; Cwirlej-Sozanska, Agnieszka; Garin Boronat, Olatz, 1979-; Ferrer Forés, Maria Montserrat; Pont Acuña, Àngels; Côté, Pierre (BioMed Central, 2023)

  Background: The World Health Organization Disability Assessment Schedule 2.0 12-item survey (WHODAS-12) is a questionnaire developed by the WHO to measure functioning across health conditions, cultures, and settings. ...

View more