• The interferon γ pathway enhances pluripotency and X-chromosome reactivation in iPSC reprogramming

  Barrero Asencio, Mercedes; Lazarenkov, Aleksey; Blanco, Enrique; Palma, Luis G.; López Rubio, Anna V.; Bauer, Moritz, 1987-; Bigas Salvans, Anna; Di Croce, Luciano; Sardina, Jose Luis; Payer, Bernhard (American Association for the Advancement of Science (AAAS), 2024)

  Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) requires activation of the pluripotency network and resetting of the epigenome by erasing the epigenetic memory of the somatic state. In female mouse ...
• Five decades of occupational cancer epidemiology

  Turner, Michelle C.; Straif, Kurt; Kogevinas, Manolis; Schubauer-Berigan, Mary K. (Nordic Association of Occupational Safety and Health (NOROSH), 2024)

  Objective: In this discussion paper, we provide a narrative review of past and present occupational cancer studies in the journal with a viewpoint towards future occupational cancer research. Method: We reviewed all ...
• Health-related quality of life in long-term colorectal cancer survivors

  Marcos-Delgado, Alba; Martín Sánchez, Vicente; Molina-Barceló, Ana; Alonso-Molero, Jéssica; Pérez-Gómez, Beatriz; Pollán, Marina; Aragonés, Núria; Ederra, María; Fernández-Tardón, Guillermo; Binefa, Gemma; Moreno, Víctor; Barrios-Rodríguez, Rocío; Amiano, Pilar; Huerta, José María; Pastor Teso, Enrique; Alguacil Ojeda, Juan; Castaño Vinyals, Gemma; Kogevinas, Manolis; Molina de la Torre, Antonio José (MDPI, 2024)

  The aim of our study is to evaluate the relationship between sociodemographic and clinical characteristics of individuals with Colorectal Cancer (CRC), tumour-intrinsic characteristics and treatment received with health-related ...
• Sex-specific chrono-nutritional patterns and association with body weight in a general population in Spain (GCAT study)

  Pons-Muzzo, Luciana; Cid Ibeas, Rafael de; Obón-Santacana, Mireia; Straif, Kurt; Papantoniou, Kyriaki, 1983-; Santonja, Isabel; Kogevinas, Manolis; Palomar Cros, Anna; Lassale, Camille (BioMed Central, 2024)

  Background: Altered meal timing patterns can disrupt the circadian system and affect metabolism. Our aim was to describe sex-specific chrono-nutritional patterns, assess their association with body mass index (BMI) and ...
• Functional structure of local connections and differentiation of cerebral cortex areas in the neonate

  Pujol, Jesús; Blanco Hinojo, Laura, 1981-; Persavento, Cecilia; Martínez-Vilavella, Gerard; Falcón, Carles; Gascon Merlos, Mireia, 1984-; Rivas, Ioar; Vilanova, Marc; Deus, Joan; Gispert López, Juan Domingo; Gómez-Roig, María Dolores; Llurba, Elisa; Dadvand, Payam; Sunyer Deu, Jordi (Elsevier, 2024)

  Neuroimaging research on functional connectivity can provide valuable information on the developmental differentiation of the infant cerebral cortex into its functional areas. We examined healthy neonates to comprehensively ...
• Association between different diet quality scores and depression risk: the REGICOR population-based cohort study

  Lugon, Gabriela; Hernáez, Álvaro; Jacka, Felice N.; Marrugat de la Iglesia, Jaume; Ramos, Rafel; Garre-Olmo, Josep; Elosua Llanos, Roberto; Lassale, Camille (Springer, 2024)

  Background: Our aim was to determine the association between diet quality and depression incidence in the population-based REGICOR cohort study, Catalonia, Spain. Methods: Prospective observational study using participants' ...
• CRUSE - What the first 100 days have taught us

  Neisinger, Sophia; Sousa Pinto, Bernardo; Ramanauskaite, Aiste; Bousquet, Jean; Weller, Karsten; Metz, Martin; Magerl, Markus; Kocatürk, Emek; Cherrez-Ojeda, Ivan; Giménez Arnau, Anna Maria; Maurer, Marcus (Hamad bin Khalifa University Press, 2023)

  Introduction: Health apps play an increasing role in everyday healthcare, especially for chronic diseases. The Chronic Urticaria Self Evaluation (CRUSE) is a new mobile health app for chronic spontaneous urticaria (CSU) ...
• Aspirin but not statins is inversely related to gastric cancer with a duration-risk effect: Results from the Stomach Cancer Pooling Project Consortium

  Pastorino, Roberta; Castaño Vinyals, Gemma; Boccia, Stefania (Wiley, 2024)

  Background: Aspirin and statins have been suggested to have potential chemopreventive effects against gastric cancer (GC), although the results of previous studies have been inconsistent. This study therefore aimed to ...
• Gut microbiota signatures of vulnerability to food addiction in mice and humans

  Samulenaite, Solveiga; García Blanco, Alejandra; Mayneris Perxachs, Jordi; Domingo Rodriguez, Laura, 1992-; Cabana-Domínguez, Judit; Fernàndez-Castillo, Noèlia; Gago-García, Edurne; Pineda-Cirera, Laura; Burokas, Aurelijus, 1982-; Espinosa-Carrasco, José; Arboleya, Silvia; Latorre, Jessica; Stanton, Catherine; Hosomi, Koji; Kunisawa, Jun; Cormand, Bru; Fernández Real, Jose M.; Maldonado, Rafael, 1961-; Martín García, Elena, 1975- (BMJ Publishing Group, 2024)

  Objective: Food addiction is a multifactorial disorder characterised by a loss of control over food intake that may promote obesity and alter gut microbiota composition. We have investigated the potential involvement of ...
• The role of cognitive reserve and clinical symptoms in the association between genetic liability for educational attainment and functioning in first-episode psychosis: a mediation analysis

  Clougher, Derek; Bergé, Daniel; PEPs Group (Cambridge University Press, 2024)

  Background: Polygenic risk scores for educational attainment (PRSEA), cognitive reserve (CR), and clinical symptoms are associated with psychosocial functioning in first-episode psychosis (FEP). Nevertheless, the mechanisms ...
• Ambient air pollution, covert cerebrovascular disease and cognition: results from the ISSYS study

  Ballvé, Alejandro; Pizarro, Jesús; Maisterra, Olga; Riba Llena, Iolanda; Pujadas, Francesc; Jiménez-Balado, Joan; Palasi, Antonio; Cirach, Marta; Turner, Michelle C.; Sunyer Deu, Jordi; Delgado, Pilar (Elsevier, 2024)

  Background and purpose: Although air pollution (AP) has been associated with stroke and dementia, data regarding its relationship with covert cerebrovascular disease (cCVD) and cognition over time are sparse. The aim of ...
• Chronic exposure to drinking water nitrate and trihalomethanes in the French CONSTANCES cohort

  Lafontaine, Antoine; Lee, Sewon; Jacquemin Leonard, Bénédicte; Glorennec, Philippe; Le Bot, Barbara; Verrey, Dominique; Goldberg, Marcel; Zins, Marie; Lequy, Emeline; Villanueva Belmonte, Cristina (Elsevier, 2024)

  Trihalomethanes (THMs) and nitrate are widespread chemicals in drinking water. Chronic exposure has been associated with increased cancer risk despite inconclusive evidence, partly due to the challenges in long-term exposure ...
• Validation of ZIP4 as a tumour-associated antigen for nanotargeting

  Xu, Ruixue; Martínez Bosch, Neus; Rivera Hueto, Francisco; Mulens-Arias, Vladimir; Rubio Moscardó, Fanny; Conesa, José Javier; Navarro, Pilar; Vicente García, Rubén, 1978-; Rivera Gil, Pilar, 1976- (Taylor & Francis, 2024)

  Pancreatic ductal adenocarcinoma remains a highly aggressive and untreatable cancer. There is a need to develop a new PDAC-associated antigen-targeting drug delivery system to tackle this disease. We validated choosing ...
• EMDR therapy vs. supportive therapy as adjunctive treatment in trauma-exposed bipolar patients: A randomised controlled trial

  Hogg, Bridget; Gardoki-Souto, Itxaso; Fontana-McNally, Marta; Lupo, Walter; Cortizo Vidal, Romina; Massó Rodriguez, Anna; Castaño, Juan R.; Castro-Rodriguez, José-Ignacio; Macías, Cristina; Sánchez-González, Roberto; Mur-Mila, Estanislao; Novo Navarro, Maria Patricia; Pérez Solá, Victor; Valiente Gómez, Alicia; Moreno Alcázar, Ana; Amann, Benedikt Lorenz (Elsevier, 2023)

  Introduction: Patients with bipolar disorder (BD) are frequently exposed to traumatic events which worsen disease course, but this study is the first multicentre randomised controlled trial to test the efficacy of a ...
• Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19

  Karachaliou, Marianna; Ranzani, Otavio; Espinosa Díaz, Ana; Iraola Guzmán, Susana; Castaño Vinyals, Gemma; Vidal, Marta; Jiménez, Alfons; Bañuls, Marc; Alonso Nogués, Eva; Aguilar, Ruth; García Aymerich, Judith; Cid Ibeas, Rafael de; Dobaño, Carlota; Moncunill, Gemma; Kogevinas, Manolis (Wiley, 2024)

  Limited research suggests that certain viruses reactivate in severe-acute-respiratory-syndrome-coronavirus 2 infection, contributing to the development of postacute sequelae of COVID-19 (PASC). We examined 1083 infected ...
• Blood concentrations of metals, essential trace elements, rare earth elements and other chemicals in the general adult population of Barcelona: Distribution and associated sociodemographic factors

  Gasull Panadès, Magda; Camargo, Judit; Pumarega Rodríguez, José Antonio; Henríquez Hernández, Luis Alberto; Campi, Laura; Zumbado, Manuel; Contreras-Llanes, Manuel; Oliveras Puig, Laura, 1987-; González Marín, Patricia; Luzardo, Octavio P.; Gómez Gutiérrez, Anna; Alguacil Ojeda, Juan; Porta Serra, Miquel (Elsevier, 2024)

  Background: Very little information is available on the population distribution and on sociodemographic predictors of body concentrations of rare earth elements (REE) and other chemicals used in the manufacturing of high-tech ...
• Brain-muscle communication prevents muscle aging by maintaining daily physiology

  Kumar, Arun; Vaca Dempere, Mireia, 1994-; Mortimer, Thomas; Deryagin, Oleg; Smith, Jacob G.; Petrus, Paul; Koronowski, Kevin B.; Greco, Carolina M.; Segalés Dalmau, Jessica; Andrés, Eva; Lukesova, Vera; Zinna, Valentina M.; Welz, Patrick-Simon; Serrano Sánchez, Antonio L.; Perdiguero, Eusebio, 1968-; Sassone-Corsi, Paolo; Aznar Benitah, Salvador; Muñoz Cánoves, Pura, 1962- (American Association for the Advancement of Science (AAAS), 2024)

  A molecular clock network is crucial for daily physiology and maintaining organismal health. We examined the interactions and importance of intratissue clock networks in muscle tissue maintenance. In arrhythmic mice showing ...
• Emergency department admissions and economic costs burden related to ambulatory care sensitive conditions in older adults living in care homes

  Afonso-Argilés, Francisco Javier; Comas Serrano, Mercè; Castells Oliveres, Xavier; Cirera Lorenzo, Isabel; García Pérez, Dolors; Pujadas Lafarga, Teresa; Ichart Tomás, Xavier; Puig-Campmany, Mireia; Vena Martínez, Ana B.; Renom-Guiteras, Anna; Caregency Group (Elsevier, 2023)

  Objectives: To assess the frequency of emergency department admissions (EDA) for ambulatory care sensitive conditions (ACSC) and non-ACSC among older adults living in care homes (CH), to describe and compare their demographic ...
• Monitoring of Pseudomonas aeruginosa mutational resistome dynamics using an enrichment panel for direct sequencing of clinical samples

  Cortes-Lara, Sara; Medina Reatiga, Paola; Barrio Tofiño, Ester del; Gomis Font, María A.; Cabot, Gabriel; Gómez Romano, Fernando; Ayestarán, Nicolás Eduardo; Colomar, Asunción; Palou Rotger, Alexandre; Oteo Iglesias, Jesús; Campo, Rosa del; Cantón, Rafael; Horcajada Gallego, Juan Pablo; López-Causapé, Carla; Oliver, Antonio (Elsevier, 2024)

  Background: Pseudomonas aeruginosa is a major cause of hospital-acquired and chronic infections, characterised by an extraordinary capacity to develop antimicrobial resistance through the selection of chromosomal mutations, ...
• A pilot study on proteomic predictors of mortality in stable COPD

  Enríquez Rodríguez, César Jessé; Casadevall Fusté, Carme; Faner, Rosa; Pascual Guàrdia, Sergi, 1979-; Castro-Acosta, Ady Angélica; López Campos, José Luis; Peces-Barba Romero, Germán; Seijo, Luis; Caguana Vélez, Oswaldo Antonio; Monsó Molas, Eduard; Rodríguez Chiaradia, Diego Agustín; Barreiro Portela, Esther; Cosío, Borja G.; Agustí García-Navarro, Àlvar; Gea Guiral, Joaquim; BIOMEPOC group (MDPI, 2024)

  Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of global mortality. Despite clinical predictors (age, severity, comorbidities, etc.) being established, proteomics offers comprehensive biological ...

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