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Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Issue Date

Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Issue Date

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  • García Closas, Montserrat; Malats i Riera, Núria; Kogevinas, Manolis; Serra, Consol; Lloreta Trull, Josep, 1958-; Real, Francisco X.; Rothman, Nathaniel (Elsevier, 2005)
    Background: Many reported associations between common genetic polymorphisms and complex diseases have not been confirmed in subsequent studies. An exception could be the association between NAT2 slow acetylation, GSTM1 ...
  • García Closas, Montserrat; Malats i Riera, Núria; Kogevinas, Manolis; Serra, Consol; Lloreta Trull, Josep, 1958-; Castaño Vinyals, Gemma; Torà, Montserrat; Fernández-Avilés, Francisco; Real, Francisco X.; Rothman, Nathaniel (Elsevier, 2005)
    BACKGROUND: Many reported associations between common genetic polymorphisms and complex diseases have not been confirmed in subsequent studies. An exception could be the association between NAT2 slow acetylation, GSTM1 ...
  • Reck, Martin; Hagiwara, Koichi; Han, Baohui; Tjulandin, Sergei; Grohé, Christian; Yokoi, Takashi; Morabito, Alessandro; Novello, Silvia; Arriola Aperribay, Edurne; Molinier, Olivier; McCormack, Rose; Ratcliffe, Marianne; Normanno, Nicola (Elsevier, 2006)
    INTRODUCTION: To offer patients with EGFR mutation-positive advanced NSCLC appropriate EGFR tyrosine kinase inhibitor treatment, mutation testing of tumor samples is required. However, tissue/cytologic samples are not ...
  • Witt, Heiko; Malats i Riera, Núria; Real, Francisco X.; Férec, Claude (Nature Research, 2006)
    Chronic pancreatitis is a common inflammatory disease of the pancreas. Mutations in the genes encoding cationic trypsinogen (PRSS1) and the pancreatic secretory trypsin inhibitor (SPINK1) are associated with chronic ...
  • Scott, Kate M.; Korff, Michael von; Ormel, Johan; Zhang, Ming-yuan; Bruffaerts, Ronny; Alonso Caballero, Jordi; Kessler, Ronald C.; Tachimori, Hisateru; Karam, Elie G.; Levinson, Daphna; Bromet, Evelyn J.; Posada Villa, José; Gasquet, Isabelle; Angermeyer, Matthias C.; Borges, Guilherme; Girolamo, Giovanni de; Herman, Allen; Haro Abad, Josep Maria (Elsevier, 2007)
    OBJECTIVE: Our objectives were (a) to determine which common mental disorders are associated with asthma in the general population after controlling for age and sex, and (b) to assess whether the associations of mental ...
  • Kessler, Ronald C.; Amminger, G. Paul; Aguilar-Gaxiola, Sergio; Alonso Caballero, Jordi; Lee, Sing; Ustun, T. Bedirhan (Lippincott Williams & Wilkins, 2007)
    PURPOSE OF REVIEW: The aim of this article is to review recent epidemiological research on age-of-onset of mental disorders, focusing on the WHO World Mental Health surveys. RECENT FINDINGS: Median and inter-quartile range ...
  • Scott, Kate M.; Korff, Michael von; Alonso Caballero, Jordi; Angermeyer, Matthias C.; Bromet, Evelyn J.; Bruffaerts, Ronny; Girolamo, Giovanni de; de Graaf, Ron; Fernández, Alberto; Gureje, Oye; He, Yanling; Kessler, Ronald C.; Kovess, Viviane; Levinson, Daphna; Medina Mora, Maria Elena; Mneimneh, Zeina N.; Browne, Mark Oakley; Posada Villa, José; Tachimori, Hisateru; Williams, David R. (Cambridge University Press, 2008)
    BACKGROUND: Physical morbidity is a potent risk factor for depression onset and clearly increases with age, yet prior research has often found depressive disorders to decrease with age. This study tests the possibility ...
  • de Graaf, Ron; Kessler, Ronald C.; Fayyad, John; ten Have, Margreet; Alonso Caballero, Jordi; Angermeyer, Matthias C.; Borges, Guilherme; Demyttenaere, Koen; Gasquet, Isabelle; Girolamo, Giovanni de; Haro Abad, Josep Maria; Jin, Robert; Karam, Elie G.; Ormel, Johan; Posada Villa, José (BMJ Publishing Group, 2008)
    OBJECTIVES: To estimate the prevalence and workplace consequences of adult attention-deficit/hyperactivity disorder (ADHD). METHODS: An ADHD screen was administered to 18-44-year-old respondents in 10 national surveys in ...
  • Buist-Bouwman, M.A.; Ormel, Johan; de Graaf, Ron; de Jonge, Peter; van Sonderen, Eric; Alonso Caballero, Jordi; Bruffaerts, Ronny; Vollebergh, Wilma; ESEMeD/MHEDEA 2000 investigators (Wiley-VCH Verlag, 2008)
    OBJECTIVE: While the adverse effect of Major Depressive Episode on role functioning is well established, the exact pathways remain unclear. METHOD: Data from The European Study of the Epidemiology of Mental Disorders, a ...
  • Rovira Clusellas, Meritxell; Delaspre, Fabien; Massumi, Mohammad; Serra Pascual, Selma A., 1981-; Valverde, M. A. (Miguel Ángel), 1963-; Lloreta Trull, Josep, 1958-; Dufresne, Marlène; Payré, Bruno; Konieczny, Stephen F.; Savatier, Pierre; Real, Francisco X.; Skoudy, Anouchka (Elsevier, 2008)
    Background & Aims: Acinar cells constitute 90% of the pancreas epithelium, are polarized, and secrete digestive enzymes. These cells play a crucial role in pancreatitis and pancreatic cancer. However, there are limited ...
  • Lin, Elizabeth H.B.; Korff, Michael von; Alonso Caballero, Jordi; Angermeyer, Matthias C.; Anthony, James C.; Bromet, Evelyn J.; Bruffaerts, Ronny; Gasquet, Isabelle; Girolamo, Giovanni de; Gureje, Oye; Haro Abad, Josep Maria; Karam, Elie G.; Lara, Carmen; Lee, Sing; Levinson, Daphna; Ormel, Johan; Posada Villa, José; Scott, Kate M.; Watanabe, Masami; Williams, David R. (Elsevier, 2008)
    OBJECTIVE: To estimate 12-month prevalence rate of mood, anxiety, and alcohol-use disorders among community samples of diabetic persons. We assess whether associations of specific mental disorders with diabetes are consistent ...
  • Korff, Michael von; Crane, Paul K.; Alonso Caballero, Jordi; Vilagut Saiz, Gemma, 1975-; Angermeyer, Matthias C.; Bruffaerts, Ronny; Girolamo, Giovanni de; Gureje, Oye; de Graaf, Ron; Huang, Yueqin; Iwata, Noboru; Karam, Elie G.; Kovess, Viviane; Lara, Carmen; Levinson, Daphna; Posada Villa, José; Scott, Kate M.; Ormel, Johan (Elsevier, 2008)
    OBJECTIVE: The WHODAS-II was substantially modified for use in the World Mental Health Surveys. This article considers psychometric properties and implications of filter items used to reduce respondent burden of the modified ...
  • He, Yanling; Alonso Caballero, Jordi; Kessler, Ronald C. (Cambridge University Press, 2008)
    BACKGROUND: Prior studies in the USA have reported higher rates of mental disorders among persons with arthritis but no cross-national studies have been conducted. In this study the prevalence of specific mental disorders ...
  • Pizarro Lozano, Mª Nieves; Torre Fornell, Rafael de la; Joglar Tamargo, Jesús; Okumura, Noriko; Perfetti, Ximena; Lau, Serrine S.; Monks, Terrence J. (American Chemical Society (ACS), 2008)
    3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a synthetic recreational drug of abuse that produces long-term toxicity associated with the degeneration of serotonergic nerve terminals. In various animal models, direct ...
  • Alonso Caballero, Jordi; Buron Pust, Andrea; The World Mental Health Consortium (Wiley-Blackwell, 2008)
    Objective: We assessed the prevalence of perceived stigma among persons with mental disorders and chronic physical conditions in an international study. Method: Perceived stigma (reporting health‐related embarrassment and ...
  • Wanami, Luke S.; Chen, Hsin-Ying; Peir, Sandóra; García de Herreros, Antonio; Bachelder, Robin E. (Elsevier, 2008)
    The E-cadherin transcriptional repressor Snail is a prognostic marker for metastatic breast carcinoma, as well as a critical determinant of tumor growth and recurrence. We define a non-angiogenic, autocrine function for ...
  • Moore, Lee E.; Pfeiffer, Ruth M.; Poscablo, Cristina; Real, Francisco X.; Kogevinas, Manolis; Silverman, Debra T.; García Closas, Reina; Chanock, Stephen J.; Tardón, Adonina; Serra, Consol; Carrato, Alfredo; Dosemeci, Mustafa; García Closas, Montserrat; Esteller, Manel; Fraga, Mario F.; Rothman, Nathaniel; Malats i Riera, Núria (Elsevier, 2008)
    BACKGROUND: DNA hypomethylation has been suggested to cause genomic instability and increase cancer risk. We aimed to test the hypothesis that DNA hypomethylation is associated with increased risk of bladder cancer. METHODS: ...
  • Djebali, Sarah; Lagarde, Julien; Denoeud, France; Guigó Serra, Roderic (Nature Research, 2008)
    Rapid amplification of cDNA ends (RACE) is a widely used approach for transcript identification. Random clone selection from the RACE mixture, however, is an ineffective sampling strategy if the dynamic range of transcript ...
  • Villanueva, Cristina M.; Silverman, Debra T.; Murta-Nascimento, Cristiane; Malats i Riera, Núria; García Closas, Montserrat; Castro Domínguez, Francisco; Tardón, Adonina; García Closas, Reina; Serra, Consol; Carrato, Alfredo; Rothman, Nathaniel; Real, Francisco X.; Dosemeci, Mustafa; Kogevinas, Manolis (Springer, 2009)
    Objective: We evaluated the bladder cancer risk associated with coffee consumption in a case–control study in Spain and examined the gene–environment interactions for genetic variants of caffeine-metabolizing enzymes. ...
  • Carracedo, Alma; Egervari, Kristof; Salido, Marta; Rojo, Federico; Arumí, Montserrat; Corominas Torres, Josep Maria; Corzo, Cristina; Tusquets Trias de Bes, Ignacio; Espinet Solà, Blanca; Rovira Guerín, Ana; Albanell Mestres, Joan; Szollosi, Zoltan; Serrano Figueras, Sergi; Solé Ristol, Francesc (BioMed Central, 2009)

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