Benvinguts al Repositori Digital de la UPF

Visualitzant Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) per data de publicació

Visualitzant Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) per data de publicació

Ordena per: Ordre: Resultats:

  • Reck, Martin; Hagiwara, Koichi; Han, Baohui; Tjulandin, Sergei; Grohé, Christian; Yokoi, Takashi; Morabito, Alessandro; Novello, Silvia; Arriola Aperribay, Edurne; Molinier, Olivier; McCormack, Rose; Ratcliffe, Marianne; Normanno, Nicola (Elsevier, 2006)
    INTRODUCTION: To offer patients with EGFR mutation-positive advanced NSCLC appropriate EGFR tyrosine kinase inhibitor treatment, mutation testing of tumor samples is required. However, tissue/cytologic samples are not ...
  • Carracedo, Alma; Egervari, Kristof; Salido, Marta; Rojo, Federico; Arumí, Montserrat; Corominas Torres, Josep Maria; Corzo, Cristina; Tusquets Trias de Bes, Ignacio; Espinet Solà, Blanca; Rovira Guerín, Ana; Albanell Mestres, Joan; Szollosi, Zoltan; Serrano Figueras, Sergi; Solé, Francesc (BioMed Central, 2009)
  • Gitter, Anthony; Siegfried, Zehava; Klutstein, Michael; Fornés Crespo, Oriol, 1983-; Oliva Miguel, Baldomero; Simon, Itamar; Bar-Joseph, Ziv (EMBO Press, 2009)
    The complementarity of gene expression and protein-DNA interaction data led to several successful models of biological systems. However, recent studies in multiple species raise doubts about the relationship between these ...
  • Balcells Vilarnau, Eva, 1967-; Antó i Boqué, Josep Maria; Gea Guiral, Joaquim; Gómez, Federico P.; Rodríguez, Esther; Marin, Alicia; Ferrer, Antoni-Lluc, 1942-; De Batlle, Jordi; Farrero, Eva; Benet, Marta; Orozco Levi, Mauricio; Ferrer, Jaume; Agustí, Alvar; Gáldiz, Juan B.; Belda, José; García Aymerich, Judith (Elsevier, 2009)
    BACKGROUND: This study describes the characteristics of a large sample of patients hospitalised for the first time for a chronic obstructive pulmonary disease (COPD) exacerbation. METHODS: All subjects first admitted for ...
  • Selent, Jana; Sanz, Ferran; Pastor Maeso, Manuel; De Fabritiis, Gianni (Public Library of Science (PLoS), 2010)
    G-protein coupled receptors, the largest family of proteins in the human genome, are involved in many complex signal transduction pathways, typically activated by orthosteric ligand binding and subject to allosteric ...
  • Stein, Dan J.; Alonso Caballero, Jordi; Nock, Matthew K (Public Library of Science (PLoS), 2010)
    Background: Community and clinical data have suggested there is an association between trauma exposure and suicidal behavior (i.e., suicide ideation, plans and attempts). However, few studies have assessed which traumas ...
  • Larriba, María Jesús; Casado Vela, Juan; Pendás Franco, Natalia; Peña, Raúl; García de Herreros, Antonio; Berciano, María Teresa; Lafarga, Miguel; Casal, José Ignacio; Muñoz, Alberto (Public Library of Science (PLoS), 2010)
    Background: The transcription factor Snail1 induces epithelial-to-mesenchymal transition (EMT), a process responsible for the acquisition of invasiveness during tumorigenesis. Several transcriptomic studies have ...
  • Cantor, Kenneth P; Villanueva Belmonte, Cristina; Silverman, Debra T.; Figueroa, Jonine D.; Real, Francisco X.; García Closas, Montserrat; Malats i Riera, Núria; Chanock, Stephen J.; Yeager, Meredith; Tardón, Adonina; García Closas, Reina; Serra, Consol; Carrato, Alfredo; Castaño Vinyals, Gemma; Samanic, Claudine; Rothman, Nathaniel; Kogevinas, Manolis (National Institute of Environmental Health Sciences (NIEHS), 2010)
    Background: Bladder cancer has been linked with long-term exposure to disinfection by-products (DBPs) in drinking water.Objectives: In this study we investigated the combined influence of DBP exposure and polymorphisms in ...
  • Vilaró Casamitjana, Jordi; Ramírez Sarmiento, Alba; Martínez-Llorens, Juana Mª; Mendoza, Teresa; Álvarez, Miguel; Sánchez Cayado, Natalia; Vega, Ángeles; Gimeno Santos, Elena, 1980-; Coronell Coronell, Carlos Gustavo; Gea Guiral, Joaquim; Roca, Josep; Orozco Levi, Mauricio (Elsevier, 2010)
    Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with several modifiable (sedentary life-style, smoking, malnutrition, hypoxemia) and non-modifiable (age, co-morbidities, severity of pulmonary ...
  • Estrada, Maria Dolors; Rajmil Rajmil, Luis Alberto; Serra Sutton, Vicky; Tebé, Cristian; Alonso Caballero, Jordi; Herdman, Michael; Riley, Anne W.; Forrest, Christopher B.; Starfield, Barbara (BioMed Central, 2010)
    Background: The objectives of the study were to assess the reliability, and the content, construct, and convergent validity of the Spanish version of the CHIP-CE/PRF, to analyze parent-child agreement, and compare the ...
  • Rebollo, Pablo; Castejón, Ignacio; Cuervo, Jesús; Villa, Guillermo; García-Cueto, Eduardo; Díaz-Cuervo, Helena; Zardain, Pilar C.; Muñiz, José; Alonso Caballero, Jordi; Spanish CAT-Health Research Group (BioMed Central, 2010)
    Background: Health Related Quality of Life (HRQoL) is a relevant variable in the evaluation of health outcomes. Questionnaires based on Classical Test Theory typically require a large number of items to evaluate HRQoL. ...
  • Voll-Aanerud, Marianne; Eagan, Thomas ML; Plana, Estel; Omenaas, Ernst R; Bakke, Per S; Svanes, Cecilie; Siroux, Valérie; Pin, Isabelle; Antó i Boqué, Josep Maria; Leynaert, Bénédicte (BioMed Central, 2010)
    Background: Respiratory symptoms are common in the general population, and their presence is related to Health-related quality of life (HRQoL). The objective was to describe the association of respiratory symptoms with ...
  • Casagolda, David; Valle Pérez, Beatriz del; Valls, Gabriela; Lugilde, Ero; Vinyoles, Meritxell; Casado Vela, Juan; Solanas, Guiomar; Batlle Gómez, Eduard; Reynolds, Albert B.; Casal, José Ignacio; García de Herreros, Antonio; Duñach, Mireia (Company of Biologists, 2010)
    p120-catenin is an E-cadherin-associated protein that modulates E-cadherin function and stability. We describe here that p120-catenin is required for Wnt pathway signaling. p120-catenin binds and is phosphorylated by CK1ε ...
  • Güerri Fernández, Roberto; Gayete, Angel; Balcells Vilarnau, Eva, 1967-; Ramírez Sarmiento, Alba; Vollmer, Ivan; García Aymerich, Judith; Gea Guiral, Joaquim; Orozco Levi, Mauricio (Elsevier, 2010)
    BACKGROUND: The potential role of decreased respiratory muscle mass, if any, in mediating the susceptibility to exacerbation in COPD patients has not been determined. We hypothesized that a decrease in respiratory muscle ...
  • Fuxe, Jonas; Vincent, Theresa; García de Herreros, Antonio (Taylor & Francis (Routledge), 2010)
    Tumor cells undergoing the epithelial-mesenchymal transition (EMT) acquire the capacity to migrate, invade the stroma and metastasize. EMT cells also acquire stem cell characteristics suggesting crosstalk between EMT and ...
  • Mokkink, Lidwine B.; Terwee, Caroline B.; Patrick, Donald L.; Alonso Caballero, Jordi; Stratford, Paul W.; Knol, Dirk L.; Bouter, Lex M.; De Vet, Henrica C. W. (Springer, 2010)
    BACKGROUND: Aim of the COSMIN study (COnsensus-based Standards for the selection of health status Measurement INstruments) was to develop a consensus-based checklist to evaluate the methodological quality of studies on ...
  • Rodríguez Santiago, Benjamín; Malats i Riera, Núria; Rothman, Nathaniel; Armengol i Dulcet, Lluís; García Closas, Montserrat; Kogevinas, Manolis; Villa, Olaya; Hutchinson, Amy; Earl, Julie; Marenne, Gaëlle; Jacobs, Kevin; Rico, Daniel; Tardón, Adonina; Carrato, Alfredo; Thomas, Gilles; Valencia, Alfonso; Silverman, Debra T.; Real, Francisco X.; Chanock, Stephen J.; Pérez Jurado, Luis Alberto (Elsevier, 2010)
    Mosaicism is defined as the coexistence of cells with different genetic composition within an individual, caused by postzygotic somatic mutation. Although somatic mosaicism for chromosomal abnormalities is a well-established ...
  • Garin Boronat, Olatz, 1979-; Ayuso Mateos, José Luis; Almansa, Josué; Nieto, Marta; Chatterji, Somnath; Vilagut Saiz, Gemma, 1975-; Alonso Caballero, Jordi; Cieza, Alarcos; Svetskova, Olga; Burger, Helena; Racca, Vittorio; Francescutti, Carlo; Vieta, Eduard; Kostanjsek, Nenad; Raggi, Alberto; Leonardi, Matilde; Ferrer Forés, Maria Montserrat; MHADIE consortium (BioMed Central, 2010)
    Background: The WHODAS-2 is a disability assessment instrument based on the conceptual framework of the International Classification of Functioning, Disability, and Health (ICF). It provides a global measure of disability ...
  • König, Hans-Helmut; Heider, Dirk; Lehnert, Thomas; Riedel-Heller, Steffi G.; Angermeyer, Matthias C.; Vilagut Saiz, Gemma, 1975-; Bruffaerts, Ronny; Haro Abad, Josep Maria; De Girolamo, Giovanni; de Graaf, Ron; Kovess, Viviane; Alonso Caballero, Jordi; ESEMeD/MHEDEA 2000 investigators (BioMed Central, 2010)
    Background: Due to demographic change, the advanced elderly represent the fastest growing population group in Europe. Health problems tend to be frequent and increasing with age within this cohort. Aims of the study: To ...
  • ten Have, Margreet; de Graaf, Ron; Ormel, Johan; Vilagut Saiz, Gemma, 1975-; Kovess, Viviane; Alonso Caballero, Jordi; ESEMeD/MHEDEA 2000 investigators (Springer, 2010)
    OBJECTIVE: To investigate the prevailing attitudes towards mental health help-seeking in Europe, their correlates, and whether these attitudes are associated with actual service use for mental health problems. METHOD: Data ...