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Browsing Articles (Hospital del Mar Research Institute) by Author "Friedländer, Marc R."

Browsing Articles (Hospital del Mar Research Institute) by Author "Friedländer, Marc R."

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  • Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome
    Bustamante Pineda, Mariona; Hernandez-Ferrer, Carles, 1987-; Tewari, Angela; Sarria-Trujillo, Yaris; Harrison, Graham I.; Puigdecanet Riubugent, Eulàlia; Nonell Mazelón, Lara; Kang, W.; Friedländer, Marc R.; Estivill, Xavier, 1955-; González, Juan Ramón; Nieuwenhuijsen, Mark J.; Young, Antony R. (Wiley, 2019)
    BACKGROUND: Terrestrial ultraviolet (UV) radiation causes erythema, oxidative stress, DNA mutations and skin cancer. Skin can adapt to these adverse effects by DNA repair, apoptosis, keratinization and tanning. OBJECTIVES: ...
  • Evidence for the biogenesis of more than 1,000 novel human microRNAs
    Friedländer, Marc R.; Lizano González, Esther, 1974-; Houben, Anna JS; Bezdan, Daniela; Bañez Coronel, Mónica; Kudla, Grzegorz; Mateu Huertas, Elisabet, 1983-; Kagerbauer, Birgit; González Morilla, Justo; Chen, Kevin C; LeProust, Emily M; Martí Puig, Eulàlia; Estivill, Xavier, 1955- (BioMed Central, 2014)
    Background: MicroRNAs (miRNAs) are established regulators of development, cell identity and disease. Although nearly two thousand human miRNA genes are known and new ones are continuously discovered, no attempt has been ...
  • The acute effects of ultraviolet radiation on the blood transcriptome are independent
    Bustamante Pineda, Mariona; Hernandez-Ferrer, Carles, 1987-; Sarria-Trujillo, Yaris; Harrison, Graham I.; Nonell Mazelón, Lara; Kang, Wenjing; Friedländer, Marc R.; Estivill, Xavier, 1955-; González, Juan Ramón; Nieuwenhuijsen, Mark J.; Young, Antony R. (Elsevier, 2017)
    The molecular basis of many health outcomes attributed to solar ultraviolet radiation (UVR) is unknown. We tested the hypothesis that they may originate from transcriptional changes in blood cells. This was determined by ...
  • The circulating transcriptome as a source of biomarkers for melanoma
    Solé, Carla; Tramonti, Daniela; Schramm, Maike; Goicoechea, Ibai; Armesto, María; Hernandez, Luiza I.; Manterola, Lorea; Fernandez-Mercado, Marta; Mujika, Karmele; Tuneu, Anna; Jaka, Ane; Tellaetxe, Maitena; Friedländer, Marc R.; Estivill, Xavier, 1955-; Piazza, Paolo; Ortiz-Romero, Pablo L.; Middleton, Mark R.; Lawrie, Charles H. (MDPI, 2019)
    The circulating transcriptome is a valuable source of cancer biomarkers, which, with the exception of microRNAs (miRNAs), remains relatively unexplored. To elucidate which RNAs are present in plasma from melanoma patients ...

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