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Browsing Articles (Hospital del Mar Research Institute) by Title
Now showing items 1488-1507 of 5003
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(Akadémiai Kiadó (AKJournals), 2019)Background and aims: DSM-5 includes Internet gaming disorder (IGD) as a condition for further study. While online and offline gaming may produce undesired negative effects on players, we know little about the nosology of ...
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(Wolters Kluwer (LWW), 2017)Mood and substance use disorders (SUDs) are mental conditions that are highly prevalent in the general population. Cooccurrence of major depression and SUD, also known as dual depression, is very common in the field of ...
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Dual disorders in the consultation liaison addiction service: Gender perspective and quality of life(MDPI, 2021)Dual disorders (DD) and gender differences comprise an area of considerable concern in patients with substance use disorder (SUD). This study aims to describe the presence of DD among patients with SUD admitted to a general ...
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(American Chemical Society (ACS), 2018)Recent network and system biology analyses suggest that most complex diseases are regulated by robust and highly interconnected pathways that could be better modulated by small molecules binding to multiple biological ...
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(Springer, 2022)Background: we aimed to determine the effect of dual anti-HER2 blockade compared to monotherapy on clinically important outcomes. Methods: we carried out a systematic review updated until July 2022. The outcomes included ...
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(Frontiers, 2017)Allograft rejection constitutes a major complication of solid organ transplantation requiring prophylactic/therapeutic immunosuppression, which increases susceptibility of patients to infections and cancer. Beyond the ...
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(Frontiers, 2023)Dual targeted therapy (DTT) has emerged as a promising approach in patients with refractory spondyloarthritis (SpA) or psoriatic arthritis (PsA) and extra-musculoskeletal manifestations of both diseases, but its ...
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(Societat Catalana de Salut Laboral, 2016)FUNDAMENTOS: Los trastornos músculo-esqueléticos (TME) son la primera causa de incapacidad temporal (IT) en España y la segunda en Cataluña. Profundizar en el conocimiento de la IT por TME podría orientar las políticas de ...
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(Nature Publishing Group, 2017)While the therapeutic effect of opioids analgesics is mainly attributed to µ-opioid receptor (MOR) activation leading to G protein signaling, their side effects have mostly been linked to β-arrestin signaling. To shed light ...
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(Wiley, 2021)IκBs exert principal functions as cytoplasmic inhibitors of NF-kB transcription factors. Additional roles for IκB homologues have been described, including chromatin association and transcriptional regulation. Phosphorylated ...
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(Wiley, 2016)Resting-state fMRI (RS-fMRI) has become a useful tool to investigate the connectivity structure of mental health disorders. In the case of major depressive disorder (MDD), recent studies regarding the RS-fMRI have found ...
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(Elsevier, 2021)Background: kidney allograft failure is a common cause of end-stage renal disease. We aimed to develop a dynamic artificial intelligence approach to enhance risk stratification for kidney transplant recipients by generating ...
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(Public Library of Science (PLoS), 2014)Functional selectivity is a property of G protein-coupled receptors that allows them to preferentially couple to particular signaling partners upon binding of biased agonists. Publication of the X-ray crystal structure of ...
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(MDPI, 2021)Background: the evolution and predictors of cognitive impairment (CI) in multiple sclerosis (MS) are poorly understood. We aimed to define the temporal dynamics of cognition throughout the disease course and identify ...
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(MDPI, 2023)The clinical manifestations of SARS-CoV-2 infection vary widely, from asymptomatic infection to the development of acute respiratory distress syndrome (ARDS) and death. The host response elicited by SARS-CoV-2 plays a key ...
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(MDPI, 2019)Genetic and phenotypic heterogeneity contribute to the generation of diverse tumor cell populations, thus enhancing cancer aggressiveness and therapy resistance. Compared to genetic heterogeneity, a consequence of mutational ...
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(Oxford University Press, 2021)Eating habits leading to obesity may reflect nonhomeostatic behavior based on excessive immediate-reward seeking. However, it is currently unknown to what extent excess weight is associated with functional alterations in ...
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(American Hearth Association, 2020)Background: Studies have failed to establish a clear link between high-density lipoprotein (HDL) cholesterol and cardiovascular disease, leading to the hypothesis that the atheroprotective role of HDL lies in its biological ...
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(MDPI, 2022)Recent works have demonstrated a significant reduction in cholesterol levels and increased oxidative stress in patients with coronavirus disease 2019 (COVID-19). The cause of this alteration is not well known. This study ...
Now showing items 1488-1507 of 5003
