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Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

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  • Perearnau, Anna; Orlando, Serena; Islam, Abul, 1978-; Gallastegui Calvache, Edurne; Martínez, Jonatan; Jordan, Albert; Bigas Salvans, Anna; Aligué, Rosa; Pujol, Maria Jesús; Bachs Valldeneu, Oriol (Oxford University Press, 2017)
    The cyclin-dependent kinase inhibitor p27Kip1 (p27) also behaves as a transcriptional repressor. Data showing that the p300/CBP-associated factor (PCAF) acetylates p27 inducing its degradation suggested that PCAF and p27 ...
  • Vernet-Tomás, Maria; Baños, Núria; Sabadell Marcadal, Maria Dolores; Corominas Torres, Josep Maria; Mestre-Fusco, Antoni; Suárez-Piñera, Marina; Carreras Collado, Ramón (Wiley, 2015)
    AIM: Several predictive tools of non-sentinel lymph nodes neoplastic involvement when a positive sentinel lymph node is found have been described. However, molecular factors have been rarely evaluated to build these tools. ...
  • Marin Corral, Judith; Climent Company, María Cristina; Muñoz Bermudez, Rosana; Samper Echevarria, Maria; Dot Jordana, Irene; Vilà Vilardell, Clara; Masclans Enviz, Joan Ramon; Rodríguez, Alejandro; Martín Loeches, Ignacio; Álvarez Lerma, Francisco; H1N1 GETGAG/SEMICYUC Study Group (Elsevier, 2018)
    OBJECTIVES: To evaluate the impact of the recommendations of the SEMICYUC (2012) on severe influenza A. DESIGN: A prospective multicenter observational study was carried out. SETTING: ICU. PATIENTS: Patients infected with ...
  • Bellet, Meritxell; Ruiz, Ada; de la Peña, Lorena (SAGE Publications, 2019)
    Drug-drug interactions are of significant concern in clinical practice in oncology, particularly in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically exposed to long-term regimens. This ...
  • ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium; Deminov, German M.; Drechsel, Oliver; Ossowski, Stephan; Estivill, Xavier, 1955-; Escaramís, Geòrgia; Bosio, Mattia; Holik, Aliaksei Z.; Susak, Hana; Rabionet, Raquel; Stobbe, Miranda D.; Marquès i Bonet, Tomàs, 1975-; Navarro i Cuartiellas, Arcadi, 1969-; Gut, Ivo Glynne; Beltran, Sergi; Gut, Marta; Trotta, Jean-Remi; Whalley, Justin P.; Heath, Simon; Prasad, Aparna; Heredia Genestar, José María, 1985-; Sabarinathan, Radhakrishnan; Pich, Oriol; Gonzalez-Perez, Abel; Rubio Pérez, Carlota, 1990-; Tamborero Noguera, David; Mularoni, Loris; Deu-Pons, Jordi; Muiños, Ferran; Muyas Remolar, Francesc, 1992- (Nature Research, 2020)
    Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale . Here we report the integrative analysis of 2,658 ...
  • Masclans Enviz, Joan Ramon; Pérez-Terán, Purificación; Roca, Oriol (Elsevier, 2015)
    Acute respiratory failure represents one of the most common causes of intensive care unit admission and oxygen therapy remains the first-line therapy in the management of these patients. In recent years, high-flow oxygen ...
  • Villar Vinuesa, Rocio; Ramada Rodilla, José María, 1961-; Serra, Consol (Societat Catalana de Salut Laboral, 2017)
    Occupational and work-related skin diseases include all skin conditions (as well as those involving the mucous membranes and cutaneous annexes) that are caused, conditioned, aggravated or promoted directly or indirectly ...
  • Sanchis-Alfonso, Vicente; Alastruey-López, Diego; Ginovart, Gerard; Montesinos-Berry, Erik; García-Castro, Fabio; Ramirez-Fuentes, Cristina; Monllau García, Juan Carlos; Alberich-Bayarri, Angel; Pérez, María Angeles (Springer, 2019)
    Background: Currently, there is uncertainty regarding the long-term outcome of medial patellofemoral ligament reconstructions (MPFLr). Our objectives were: (1) to develop a parametric model of the patellofemoral joint (PFJ) ...
  • Sitges-Serra, Antonio; Lorente-Poch, Leyre; Sancho Insenser, Juan (Springer, 2018)
    BACKGROUND: Careful parathyroid gland dissection and in situ preservation was the time-honored approach to prevent parathyroid failure after total thyroidectomy. The relative success of parathyroid autotransplantation of ...
  • Gureje, Oye; Alonso Caballero, Jordi; Nock, Matthew K. (Nature Research, 2011)
    Previous research suggests that parental psychopathology predicts suicidal behavior among offspring; however, the more fine-grained associations between specific parental disorders and distinct stages of the pathway to ...
  • Rajmil Rajmil, Luis Alberto; Rodríguez López, Amanda; López Aguilà, Sílvia; Alonso Caballero, Jordi (BioMed Central, 2013)
    Background: Few studies have evaluated changes on parent–child agreement in HRQOL over time. The objectives of the study were to assess parent–child agreement on child’s HRQOL in a 3-year longitudinal study, and to identify ...
  • Cruzado, Josep M.; Lauzurica, Ricard; Pascual Santos, Julio; Marcen, Roberto; Moreso, Francesc; Gutierrez-Dalmau, Alex; Andrés, Amado; Hernández, Domingo; Torres, Armando; Beneyto, Maria Isabel; Melilli, Edoardo; Manonelles, Anna; Arias, Manuel; Praga, Manuel (Elsevier, 2017)
    INTRODUCTION: Secondary hyperparathyroidism (SHPT) and vitamin D deficiency are common at kidney transplantation and are associated with some early and late complications. This study was designed to evaluate whether ...
  • Barreiro Portela, Esther; Gea Guiral, Joaquim (De Gruyter, 2018)
    Skeletal muscle dysfunction and mass loss is a characteristic feature in patients with chronic diseases including cancer and acute conditions such as critical illness. Maintenance of an adequate muscle mass is crucial for ...
  • Echeverri Tirado, Laura C.; Ghonim, Mohamed A.; Wang, Jeffrey; Al-Khami, Amir A.; Wyczechowska, Dorota; Luu, Hanh H.; Hogyoung, Kim; Sanchez-Pino, Maria Dulfary; Yélamos López, José; Yassin, Lina M.; Boulares, A. Hamid (Hindawi, 2019)
    Dendritic cells (DCs) are critical in asthma and many other immune diseases. We previously demonstrated a role for PARP-1 in asthma. Evidence on PARP-1 playing a role in Th2-associated DC function is not clear. In this ...
  • Rodríguez, María Isabel; Peralta-Leal, Andreína; O'Valle, Francisco; Rodríguez-Vargas, José Manuel; González-Flores, Ariannys; Majuelos-Melguizo, Jara; López Muñoz, Laura; Serrano, Santiago; García de Herreros, Antonio; Rodríguez-Manzaneque, Juan Carlos; Fernández Montes, Rubén D.; del Moral, Raimundo G.; de Almodovar, José Mariano; Oliver, F. Javier (Public Library of Science (PLoS), 2013)
    PARP inhibition can induce anti-neoplastic effects when used as monotherapy or in combination with chemo- or radiotherapy in various tumor settings; however, the basis for the anti-metastasic activities resulting from PARP ...
  • Navarro, Judith; Gozalbo-López, Beatriz; Méndez, Andrea C.; Dantzer, Françoise; Schreiber, Valérie; Martínez, Carlos; Arana, David M.; Farrés, Jordi; Revilla-Nuin, Beatriz; Bueno, María F.; Ampurdanés, Coral; Galindo-Campos, Miguel A.; Knobel, Philip A.; Segura-Bayona, Sandra; Martin-Caballero, Juan; Stracker, Travis; Aparicio, Pedro; Del Val, Margarita; Yelamos López, Jose (Nature Publishing Group, 2017)
    The maintenance of T-cell homeostasis must be tightly regulated. Here, we have identified a coordinated role of Poly(ADP-ribose) polymerase-1 (PARP-1) and PARP-2 in maintaining T-lymphocyte number and function. Mice bearing ...
  • Johnson, Brett V.; Pérez Jurado, Luis Alberto; Jolly, Lachlan A. (Elsevier, 2020)
    Background: The X-chromosome gene USP9X encodes a deubiquitylating enzyme that has been associated with neurodevelopmental disorders primarily in female subjects. USP9X escapes X inactivation, and in female subjects de ...
  • Leal Blanquet, Joan; Alentorn Geli, Eduard; Torres Claramunt, Raúl; Monllau García, Juan Carlos (Elsevier, 2017)
    Medial patellofemoral ligament (MPFL) reconstruction for patellofemoral instability is a common procedure. Although MPFL reconstruction is a successful procedure in terms of return to normal life or sports, revision cases ...
  • García, Ana María; Boix, Pere; Benavides, Fernando G. (Fernando García); Gadea, Rafael; Fernando, Rodrigo; Serra, Consol (Elsevier, 2016)
    Participation of stakeholders is a key requirement for the success of public health programmes. Working and employment conditions are major determinants for people's health and wellbeing, and workplaces are ideal environments ...

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