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Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

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  • Gayà Vidal, Magdalena; Albà Soler, Mar (BioMed Central, 2014)
    Background: The recent increase in human polymorphism data, together with the availability of genome sequences from several primate species, provides an unprecedented opportunity to investigate how natural selection has ...
  • Piñero González, Janet, 1977-; Berenstein, Ariel José; González-Pérez, Abel; Chernomoretz, Ariel; Furlong, Laura I., 1971- (Nature Publishing group, 2016)
    Characterizing the behavior of disease genes in the context of biological networks has the potential to shed light on disease mechanisms, and to reveal both new candidate disease genes and therapeutic targets. Previous ...
  • Ali, Syed O.; Khan, Farhaan A.; Galindo-Campos, Miguel A.; Yelamos López, Jose (e-Century Publishing, 2016)
    Poly(ADP-ribosyl)ation (PARylation) is a widespread and highly conserved post-translational modification catalysed by a large family of enzymes called poly(ADP-ribose) polymerases (PARPs). PARylation plays an essential ...
  • Rajmil Rajmil, Luis Alberto; Siddiqi, Arjumand; Taylor-Robinson, David; Spencer, Nick (BioMed Central, 2015)
    INTRODUCTION: The objectives of the study were to explore the effect of the economic crisis on child health using Spain as a case study, and to document and assess the policies implemented in response to the crisis in this ...
  • Thornicroft, Graham; Alonso Caballero, Jordi; Kessler, Ronald C. (Royal College of Psychiatrists, 2017)
    BACKGROUND: Major depressive disorder (MDD) is a leading cause of disability worldwide. AIMS: To examine the: (a) 12-month prevalence of DSM-IV MDD; (b) proportion aware that they have a problem needing treatment and who ...
  • Sisinni, Lorenza; Gimeno Martínez, Ramón; Pérez-Martínez, Antonio (Elsevier, 2018)
    The CD45RA T cell depletion (TCD) method has been used to deplete naive T cells, preventing graft-versus-host disease (GVHD) but preserving memory cells, providing immediate functional T cells with anti-infection, antileukemia, ...
  • Valls, Gabriela; Codina, Montserrat; Miller, Rachel K.; Valle Pérez, Beatriz del; Vinyoles, Meritxell; Caelles Franch, Carme; McCrea, Pierre D.; García de Herreros, Antonio; Duñach, Mireia (Company of Biologists, 2012)
    A role for Rac1 GTPase in canonical Wnt signaling has recently been demonstrated, showing that it is required for β-catenin translocation to the nucleus. In this study, we investigated the mechanism of Rac1 stimulation by ...
  • Tischer, Christina; Dadvand, Payam; Basagaña Flores, Xavier; Sunyer Deu, Jordi; Antó i Boqué, Josep Maria (Elsevier, 2018)
    Objective: We integratively assessed the effect of different indoor and outdoor environmental exposures early in life on respiratory and allergic health conditions among children from (sub-) urban areas. Methods: This study ...
  • Maitre, Léa; Robinson, Oliver; Martínez, David; Toledano, Mireille B.; Ibarluzea, Jesús; Marina, Loreto Santa; Sunyer Deu, Jordi; Villanueva, Cristina M.; Keun, Hector C.; Vrijheid, Martine; Coen, Muireann (American Chemical Society (ACS), 2018)
    Exposure to environmental pollutants, particularly during pregnancy, can have adverse consequences on child development but little is known about the effects of pollutant mixtures on endogenous metabolism in pregnant women. ...
  • Pérez-Ferriols, Amparo; Barnadas, Maria; Gardeazábal, Jesús; Argila, Diego de; Carrascosa Carrillo, José Manuel; Aguilera, Paula; Giménez Arnau, Anna Maria; Rodríguez-Granados, Teresa; Gálvez, María Victoria de; Aguilera, José (Elsevier, 2017)
    Antecedentes: La urticaria solar es una urticaria crónica inducible física clasificada también como fotodermatosis idiopática. El objetivo de este trabajo es definir las características fenotípicas y valorar la incidencia ...
  • Hinarejos Gómez, Pedro Angel; Guirro Castellnou, Pau; Puig Verdié, Luís; Torres Claramunt, Raúl; Leal Blanquet, Joan; Sánchez Soler, JF.; Monllau García, Juan Carlos (Baishideng Publishing Group, 2015)
    Bone cement has the capacity to release antibiotic molecules if any antibiotic is included in it, and these elution properties are improved as cement porosity is increased. In vitro studies have shown high local antibiotic ...
  • Dierssen Sotos, Trinidad; Servitja Tormo, Sonia; Gracia Lavedan, Esther; Castaño Vinyals, Gemma; Kogevinas, Manolis; Llorca, Javier (BioMed Central, 2016)
    Background: The relationship between non-steroidal anti-inflammatory drug (NSAID) consumption and breast cancer has been repeatedly studied, although the results remain controversial. Most case-control studies reported ...
  • Maldonado, Rafael, 1961-; Baños i Díez, Josep Eladi; Cabañero Ferri, David (Wiley, 2017)
    Several lines of knockout mice deficient in the genes encoding each component of the endogenous opioid system have been used for decades to clarify the specific role of the different opioid receptors and peptide precursors ...
  • Arias Cabrales, Carlos Enrique; Pérez-Sáez, María José; Redondo Pachón, María Dolores; Buxeda, Anna; Burballa Tarrega, Carla Cristina; Bermejo García, Sheila; Sierra Ochoa, Adriana; Mir Fontana, M. Luisa; Buron Pust, Andrea; Zapatero, Ana; Crespo Barrio, Marta; Pascual Santos, Julio (Elsevier, 2018)
    INTRODUCTION: Kidney donor shortage requires expanding donor selection criteria, as well as use of objective tools to minimize the percentage of discarded organs. Some donor pre-transplant variables such as age, standard/expanded ...
  • Mayer, Miguel Ángel, 1960-; Gutiérrez Sacristán, Alba; Leis Machin, Angela; De La Peña, Santiago; Sanz, Ferran; Furlong, Laura I., 1971- (IOS Press, 2017)
    Comorbid diseases are an important concern in oncology since they can affect the choice and effectiveness of treatment. What is particularly relevant is the fact that the diagnosis of depression in cancer patients has an ...
  • Díaz, Víctor M. (Impact Journal, 2018)
  • Sánchez Niubò, Albert; Forero, Carlos G.; Benavides, Fernando G. (Fernando García) (Sociedad Catalana de Salut Laboral y la Asociación de Medicina del Trabajo de la Comunidad Valenciana, 2016)
    Pese a que un objetivo de la epidemiología es la identificación de relaciones de causalidad entre un factor de riesgo y un problema de salud, la metodología de investigación de esta disciplina sacrifica a menudo la validez ...
  • Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto; Icaza, Gloria; Morales-Salinas, Alberto; Dégano, Irene R. ( Mednet, 2016)
    Las estrategias de prevención de las enfermedades cardiovasculares necesitan refinamiento porque su incidencia se reduce muy lentamente. Las funciones de riesgo incorporaron los factores de riesgo clásicos (edad, sexo, ...
  • Garin Boronat, Olatz, 1979-; Galante, Mariana; García Altés, Anna; Sicuri, Elisa; Cots Reguant, Francesc; Nebot, Manel; Ferrer Forés, Maria Montserrat; Domínguez García, Àngela; Alonso Caballero, Jordi (Ministerio de Sanidad y Consumo, 2011)
    Las epidemias de gripe son causa de morbi-mortalidad y tienen un gran impacto socio-económico. Ocasionalmente, los brotes de gripe generan pandemias. La última originada por el virus de la Gripe (H1N1)2009. Teniendo en ...

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