Visualitzant Articles (Hospital del Mar Research Institute) per títol

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  • Gadolinium-enhanced brain lesions in multiple sclerosis relapse
    Martín-Aguilar, Lorena; Presas-Rodriguez, Silvia; Rovira Cañellas, Àlex; Capellades Font, Jaume; Massuet-Vilamajó, Anna; Ramió-Torrentà, Lluís; Tintoré, Mar; Brieva, Luis; Moral-Torres, Ester; Cano-Orgaz, Antonio; Blanco, Yolanda; Batlle-Nadal, Jordi; Carmona, Olga; Gea, M.; Hervás-García, José V.; Ramo-Tello, Cristina (Elsevier, 2022)
    Objective: To study the clinico-radiological paradox in multiple sclerosis (MS) relapse by analyzing the number and location of gadolinium-enhanced (Gd+) lesions on brain MRI before methylprednisolone (MP) treatment. ...
  • Gag-pol processing during HIV-1 virion maturation: a systems biology approach
    Könnyű, Balázs; Sadiq, S. Kashif; Turányi, Tamás; Hírmondó, Rita; Müller, Barbara; Kräusslich, Hans-Georg; Coveney, Peter V.; Müller, Viktor (Public Library of Science (PLoS), 2013)
    Proteolytic processing of Gag and Gag-Pol polyproteins by the viral protease (PR) is crucial for the production of infectious HIV-1, and inhibitors of the viral PR are an integral part of current antiretroviral therapy. ...
  • Gal-1 expression analysis in the GLIOCAT multicenter study: Role as a prognostic factor and an immune-suppressive biomarker
    Martínez Bosch, Neus; Alameda Quitllet, Francisco; Arumí Uría, Montserrat; Bellosillo Paricio, Beatriz; Menéndez, Silvia; Esteve-Codina, Anna; Martínez-García, Maria; Navarro Medrano, Pilar (MDPI, 2023)
    Glioblastoma (GBM) is the most frequent primary malignant brain tumor and has a dismal prognosis. Unfortunately, despite the recent revolution of immune checkpoint inhibitors in many solid tumors, these have not shown a ...
  • Gasdermin B over-expression modulates HER2-targeted therapy resistance by inducing protective autophagy through Rab7 activation
    Gámez-Chiachio, Manuel; Molina-Crespo, Ángela; Ramos-Nebot, Carmen; Martinez-Val, Jeannette; Martinez, Lidia; Gassner, Katja; Llobet, Francisco J.; Soriano, Mario; Hernandez, Alberto; Cordani, Marco; Bernadó Morales, Cristina; Diaz, Eva; Rojo-Sebastian, Alejandro; Triviño Salazar, Juan Carlos; Sánchez, Laura; Rodríguez-Barrueco, Ruth; Arribas, Joaquín; Llobet-Navás, David; Sarrió, David; Moreno-Bueno, Gema (BioMed Central, 2022)
    Background: Gasdermin B (GSDMB) over-expression promotes poor prognosis and aggressive behavior in HER2 breast cancer by increasing resistance to therapy. Decoding the molecular mechanism of GSDMB-mediated drug resistance ...
  • Gastrointestinal physiological changes and their relationship to weight loss following the POSE procedure.
    Espinós, J. C.; Turró, R.; Moragas, G.; Bronstone, Amy; Buchwald, J.N.; Mearin, Fermín; Mata, A.; Uchima, H.; Turró, J.; Delgado Aros, Silvia (Springer, 2016)
    BACKGROUND: Primary Obesity Surgery Endolumenal (POSE) is a novel bariatric endoscopic procedure that has been shown to reduce weight safely through 12 months. The study investigated potential mechanisms of weight loss ...
  • GATA2 deficiency and MDS/AML: experimental strategies for disease modelling and future therapeutic prospects
    Kotmayer, Lili; Romero-Moya, Damià; Marin-Bejar, Oskar; Kozyra, Emilia; Català, Albert; Bigas Salvans, Anna; Wlodarski, Marcin W.; Bödör, Csaba; Giorgetti, Alessandra (Wiley, 2022)
    The importance of predisposition to leukaemia in clinical practice is being increasingly recognized. This is emphasized by the establishment of a novel WHO disease category in 2016 called "myeloid neoplasms with germline ...
  • Gathering and exploring scientific knowledge in pharmacovigilance
    Lopes, Pedro; Nunes, Tiago; Campos, David; Furlong, Laura I., 1971-; Bauer-Mehren, Anna; Sanz, Ferran; Carrascosa Baena, María Carmen, 1972-; Mestres i López, Jordi; Kors, Jan A.; Singh, Barat; van Mulligen, Erik M.; van der Lei, Johan; Diallo, Gayo; Avillach, Paul; Ahlberg Helgee, Ernst; Boyer, Scott; Díaz, Carlos; Oliveira, José Luis (Public Library of Science (PLoS), 2013)
    Pharmacovigilance plays a key role in the healthcare domain through the assessment, monitoring and discovery of interactions amongst drugs and their effects in the human organism. However, technological advances in this ...
  • GC-MS quantification method for mephedrone in plasma and urine: application to human pharmacokinetics
    Olesti Muñoz, Eulàlia, 1991-; Pujadas Bastardes, Mitona; Papaseit Fontanet, Esther; Pérez Mañá, Clara; Pozo Mendoza, Óscar J., 1975-; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Oxford University Press, 2017)
    Increasing consumption has been observed among young people of new psychoactive substances, including synthetic cathinone derivatives. The most well known of these is mephedrone whose use has been related to acute intoxication ...
  • GC/MS in recent years has defined the normal and clinically disordered steroidome: will it soon be surpassed by LC/Tandem MS in this role?
    Shackleton, Cedric; Pozo Mendoza, Óscar J., 1975-; Marcos del Águila, Josep, 1971- (Endocrine Society, 2018)
    Gas chromatography/mass spectrometry (GC/MS) has been used for steroid analysis since the 1960s. The advent of protective derivatization, capillary columns, and inexpensive electron ionization bench-top single quadrupole ...
  • GDF15 is an eribulin response biomarker also required for survival of DTP breast cancer cells
    Bellio, Chiara; Emperador, Marta; Castellano, Pol; Gris-Oliver, Albert; Canals, Francesc; Sánchez Pla, Alexandre; Zamora, Esther; Arribas, Joaquín; Saura, Cristina; Serra, Violeta; Tabernero Cartula, Josep; Littlefield, Bruce A.; Villanueva, Josep (MDPI, 2022)
    Drug tolerant persister (DTP) cells enter into a reversible slow-cycling state after drug treatment. We performed proteomic characterization of the breast cancer (BC) DTP cell secretome after eribulin treatment. We showed ...
  • GEICAM guidelines for the management of patients with breast cancer during the COVID-19 pandemic in Spain
    Martín, Miguel; Guerrero-Zotano, Ángel; Montero, Ángel; Jara, Carlos; Filipovich, Elena; Rojo, Federico; Moreno, Fernando; García-Sáenz, Jose Ángel; Alés, Jose Enrique; Chacón, José Ignacio; Cruz, Josefina; Giménez, Julia; Cruz-Merino, Luis; Algara López, Manuel-Ignacio; Santisteban, Marta; López Tarruella, Sara; GEICAM Spanish Breast Cancer Group Steering Committee (Oxford University Press, 2020)
    Breast cancer (BC) is the most common cancer in women in Spain. During the COVID-19 pandemic caused by the SARS-CoV-2 virus, patients with BC still require timely treatment and follow-up; however, hospitals are overwhelmed ...
  • GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program
    Lewis, Michael; Gil Gómez, Gabriel; Stracker, Travis H. (Nature Research, 2023)
    Multiciliated cells (MCCs) project dozens to hundreds of motile cilia from their apical surface to promote the movement of fluids or gametes in the mammalian brain, airway or reproductive organs. Differentiation of MCCs ...
  • GEMC1 is a critical regulator of multiciliated cell differentiation.
    Terré, Berta; Piergiovanni, Gabriele; Segura-Bayona, Sandra; Gil Gómez, Gabriel; Youssef, Sameh A.; Attolini, Camille Stephan-Otto; Wilsch-Bräuninger, Michaela; Jung, Carole; Rojas Mendoza, Ana Maria; Marjanovi c, Marko; Knobel, Philip A.; Palenzuela, Lluís; López-Rovira, Teresa; Forrow, Stephen; Huttner, Wieland B.; Valverde, M. A. (Miguel Ángel), 1963-; de Bruin, Alain; Costanzo, Vincenzo; Stracker, Travis (EMBO Press, 2016)
    The generation of multiciliated cells (MCCs) is required for the proper function of many tissues, including the respiratory tract, brain, and germline. Defects in MCC development have been demonstrated to cause a subclass ...
  • Gender analysis of the frequency and course of depressive disorders and relationship with personality traits in general population: A prospective cohort study
    Serrano, Domènec; Martí-Lluch, Ruth; Cárdenas, Mérida; Solanas, Pascual; Marrugat de la Iglesia, Jaume; Vilalta-Franch, Joan; Garre-Olmo, Josep (Elsevier, 2022)
    Background: We aimed to determine the prevalence and course of subthreshold depressive symptomatology (sDS) and probable major depressive episode (MDE) and to examine their association with personality traits among men and ...
  • Gender commonalities and differences in risk and protective factors of suicidal thoughts and behaviors: A cross-sectional study of Spanish university students
    Miranda-Mendizábal, Andrea; Torrent, Aina; Mortier, Philippe; Alonso Caballero, Jordi (Wiley, 2019)
    AIM: To assess gender differences in the association between risk/protective factors and suicidal thoughts and behaviors (STB); and whether there is any gender-interaction with those factors and STB; among Spanish university ...
  • Gender differences in cancer risk after kidney transplantation
    Buxeda, Anna; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Bartolomé, Álvaro; Mir Fontana, M. Luisa; Pascual-Dapena, Ana; Sans, Anna; Duran Jordà, Xavier, 1974-; Crespo Barrio, Marta; Pascual Santos, Julio (Impact Journals, 2019)
    Kidney transplant (KT) recipients are at greater risk of developing some cancers than the general population. Moreover, cancer is the only cause of death that is currently increasing after kidney transplantation. We analyzed ...
  • Gender differences in suicidal behavior in adolescents and young adults: systematic review and meta-analysis of longitudinal studies
    Miranda-Mendizábal, Andrea; Castellvi Obiols, Pere; Parés Badell, Oleguer; Alayo, Itxaso; Almenara, José; Alonso, Iciar; Blasco Cubedo, Maria Jesús; Cebrià, Ana Isabel; Gabilondo Cuéllar, Andrea; Gili, Margalida; Lagares, Carolina; Piqueras, José Antonio; Rodríguez Jimenez, Tiscar; Rodríguez-Marín, Jesús; Roca, Miquel; Soto-Sanz, Victoria; Vilagut Saiz, Gemma, 1975-; Alonso Caballero, Jordi (Springer, 2019)
    OBJECTIVES: To assess the association between gender and suicide attempt/death and identify gender-specific risk/protective factors in adolescents/young adults. METHODS: Systematic review (5 databases until January 2017). ...
  • Gender differences in the indirect effect of psychosocial work environment in the association of precarious employment and chronic stress: A cross-sectional mediation analysis
    Méndez-Rivero, Fabrizio; Pozo Mendoza, Óscar J., 1975-; Julià, Mireia (MDPI, 2022)
    Gender differences in the association between precarious employment and chronic stress have been found but the mechanisms underlying this relationship have not been explored. The main objective of this study was to evaluate ...
  • Gender differences in the use of alcohol and prescription drugs in relation to job insecurity. Testing a model of mediating factors.
    Colell Ortega, Esther, 1961-; Sánchez Niubò, Albert; Ferrer, Montserrat; Domingo-Salvany, Antònia (Elsevier, 2016)
    BACKGROUND: The results of several studies suggest that economy-related stressors are less distressing for women compared with men. This study proposed to examine the relationship of perceived job insecurity with the use ...
  • Gender gap in annual preventive care services in France
    Gaye, Bamba; Hergault, Hélène; Lassale, Camille; Ladouceur, Magalie; Valentin, Eugenie; Vignac, Maxime; Danchin, Nicolas; Diaw, Mor; Kvaskoff, Marina; Chamieh, Sarah; Thomas, Frederique; Michos, Erin D.; Jouven, Xavier (Elsevier, 2022)
    Background: in France, screening for cardiovascular risk factors is recommended during annual preventive visits. However, data are lacking on the temporal trend in women's uptake to preventive care services, and in ...

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