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Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

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  • Casadevall Aguilar, David; Vidal Barrull, Joana; Gallardo Hernández, Fernando; Zuccarino, Flavio; Arumí, Montserrat; Dalmases Massegú, Alba, 1982-; Bellosillo Paricio, Beatriz; Montagut Viladot, Clara (BioMed Central, 2016)
    BACKGROUND: Approximately 50 % of malignant melanomas harbor activating point mutations in the BRAF gene. Typically, these mutations result in the substitution of the amino acid valine at codon 600 of the gene, and 90-95 ...
  • Lago-Sampedro, Ana; García-Escobar, Eva; Rubio-Martín, Elehazara; Pascual-Aguirre, Nuria; Valdés, Sergio; Soriguer, Federico; Goday Arno, Alberto; Calle-Pascual, Alfonso; Castell, Conxa; Menéndez, Edelmiro; Delgado, Elías; Bordiú, Elena; Castaño, Luis; Franch-Nadal, Josep; Girbés, Juan; Chaves, Felipe Javier; Gaztambide, Sonia; Rojo-Martínez, Gemma; Olveira, Gabriel (MDPI, 2019)
    To date it is not clear what the role of dairy products is in metabolic diseases like diabetes, obesity, and hypertension. Therefore, the aim of this study is to test the association between dairy product consumption and ...
  • Díaz‑López, Andrés; Bulló, Mònica; Martínez-González, Miguel A.; Corella, Dolores; Estruch, Ramón; Fitó Colomer, Montserrat; Gómez-Gracia, Enrique; Fiol, Miquel; García de la Corte, Francisco Javier; Ros, Emilio; Babio, Nancy; Serra-Majem, Luis; Pinto, Xavier; Muñoz, Miguel Ángel; Francés, Francisco; Buil-Cosiales, P.; Salas-Salvadó, Jordi (Springer Verlag , 2016)
    PURPOSE The possible effects of dairy consumption on diabetes prevention remain controversial. The aim of this study was to investigate the association between the dairy consumption and type 2 diabetes (T2D) risk in an ...
  • Shaw, E.; Montero, M.; Pujol Llop, Mario; Spanish Network for Research in InfectiousDiseases (REIPI RD12/0015); Instituto de Salud Carlos III; GEIH (Hospital Infection Study Group) (BMJ Publishing Group:, 2015)
    INTRODUCTION: Despite the availability of new antibiotics such as daptomycin, methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia continues to be associated with high clinical failure rates. Combination therapy ...
  • Peláez García, Alberto; Barderas, Rodrigo; Mendes, Marta; López Lucendo, María; Sanchez, J.C.; García de Herreros, Antonio; Casal, José Ignacio (Elsevier, 2015)
    The transcription factor (TF) Snail1 is a major inducer of the epithelial-mesenchymal transition (EMT) during embryonic development and cancer progression. Ectopic expression of Snail in murine mesenchymal stem cells (mMSC) ...
  • Herrero Gascón, Mª Jesús; Domingo i Salvany, Antònia; Torre Fornell, Rafael de la (Elsevier, 2017)
    The data presented in this article are related to the paper "Prevalence of psychoactive substances, alcohol and illicit drugs, in Spanish drivers: A roadside study in 2015". (https://doi.org/10.1016/j.forsciint.2017.07.005) ...
  • Cardoso, Graça; Xavier, Miguel; Vilagut Saiz, Gemma, 1975-; Petukhova, Maria; Alonso, Jordi; Kessler, Ronald C.; Caldas de Almeida, José Miguel (Royal College of Psychiatrists, 2017)
    BACKGROUND: One important aspect of the societal burden of mental disorders is the extent to which these problems cause disability. AIMS: To assess days out of role associated with commonly occurring mental disorders in ...
  • Alonso Caballero, Jordi; Vilagut Saiz, Gemma, 1975-; Kessler, Ronald C. (Nature Publishing Group, 2011)
    Days out of role because of health problems are a major source of lost human capital. We examined the relative importance of commonly occurring physical and mental disorders in accounting for days out of role in 24 countries ...
  • Mall, Sumaya; Lund, Crick; Vilagut Saiz, Gemma, 1975-; Alonso Caballero, Jordi; Williams, David R.; Stein, Dan J. (Springer, 2015)
    Background: Both mental and physical disorders can result in role limitation, such as ‘days out of role’, which have an important impact on national productivity losses. This paper analyses data from the South African ...
  • Andrade, Laura Helena; Baptista, Marcos C.; Alonso Caballero, Jordi; Petukhova, Maria; Bruffaerts, Ronny; Kessler, Ronald C.; Silveira, Camila M.; Siu, Erica R.; Wang, Yuan-Pang; Viana, Maria Carmen (Hospital das Clínicas, Faculty of Medicine, University of São Paulo, 2013)
    OBJECTIVES: To investigate the relative importance of common physical and mental disorders with regard to the number of days out-of-role (DOR; number of days for which a person is completely unable to work or carry out ...
  • Mallorquí-Bagué, Nuria; Fagundo, Ana B.; Jiménez Murcia, Susana; Torre Fornell, Rafael de la; Baños, Rosa M.; Botella, Cristina; Casanueva, Felipe F.; Crujeiras, Ana B.; Fernández García, José C.; Fernández Real, Jose M.; Frühbeck, Gema; Granero, Roser; Rodríguez, Amaia; Tolosa-Sola, Iris; Ortega, Francesc; Tinahones Madueño, Francisco José; Alvarez-Moya, Eva; Ochoa, Cristian; Menchón, José M.; Fernández Aranda, Fernando (Public Library of Science (PLoS) , 2016)
    INTRODUCTION: Addictions are associated with decision making impairments. The present study explores decision making in Substance use disorder (SUD), Gambling disorder (GD) and Obesity (OB) when assessed by Iowa Gambling ...
  • Aparicio i Prat, Estel, 1986-; Arnan Ros, Carme; Sala, Ilaria; Bosch Roca, Núria; Guigó Serra, Roderic; Johnson, Rory (BioMed Central, 2015)
    Background. CRISPR genome-editing technology makes it possible to quickly and cheaply delete non-protein-coding regulatory elements. We present a vector system adapted for this purpose called DECKO (Double Excision CRISPR ...
  • Galindo Guarín, Liliana; Bergé Baquero, Daniel; Murray, Graham K.; Mané Santacana, Anna; Bulbena Vilarrasa, Antonio; Pérez Solá, Victor; Vilarroya, Óscar (Frontiers, 2018)
    Brain connectivity and neurological soft signs (NSS) are reportedly abnormal in schizophrenia and unaffected relatives, suggesting they might be useful neurobiological markers of the illness. NSS are discrete sensorimotor ...
  • Sabbaghi Mehrjardi, Mohammad Ali; Gil Gómez, Gabriel; Guardia Laguarta, Cristina; Servitja Tormo, Sonia; Arpí Llucià, Oriol; Menendez Romero, Silvia; Arumí, Montserrat; Serrano, Laia; Salido Galeote, Marta; Muntasell i Castellví, Aura, 1972-; Martínez-García, Maria; Tusquets Trias de Bes, Ignacio; Rovira Guerín, Ana; Albanell Mestres, Joan (American Association for Cancer Research (AACR), 2017)
    Purpose: Trastuzumab-emtansine (T-DM1) is a standard treatment in advanced HER2-positive breast cancer. However, resistance inevitably occurs. We aimed to identify mechanisms of acquired T-DM1 resistance.Experimental Design: ...
  • Argente, Jesús; Flores, Raquel; Gutiérrez Arumi, Armand, 1980-; Verma, Bhupendra; Martos Moreno, Gabriel A.; Cuscó Martí, Ivon, 1973-; Oghabian, Ali; Chowen, Julie A.; Frilander, Mikko J; Pérez Jurado, Luis Alberto (Wiley-VCH Verlag, 2014)
    The molecular basis of a significant number of cases of isolated growth hormone deficiency remains unknown. We describe three sisters affected with severe isolated growth hormone deficiency and pituitary hypoplasia caused ...
  • Dalmases Massegú, Alba, 1982-; González González, Irene; Menendez Romero, Silvia; Arpí Llucià, Oriol; Corominas Torres, Josep Maria; Servitja Tormo, Sonia; Tusquets, Ignasi; Chamizo, Cristina; Rincón, Raúl; Espinosa Blay, Lluís; Bigas Salvans, Anna; Eroles, Pilar; Furriol, Jessica; Lluch, Ana; Rovira Guerín, Ana; Albanell Mestres, Joan; Rojo, Federico (Impact Journals, 2014)
    NF-кB has been linked to doxorubicin resistance in breast cancer patients. NF-кB nuclear translocation and DNA binding in doxorubicin treated-breast cancer cells have been extensively examined; however its functional ...
  • Garcia-Elias Heras, Anna; Alloza, Leonor; Puigdecanet Riubugent, Eulàlia; Nonell Mazelón, Lara; Tajes Orduña, Marta; Curado, Joao; Enjuanes Grau, Cristina; Díaz, Oscar; Bruguera-Cortada, Jordi; Martí-Almor, Julio; Comín Colet, Josep; Benito Villabriga, Begoña (Nature Publishing Group, 2017)
    MicroRNAs (miRNAs) have emerged as promising biomarkers of disease. Their potential use in clinical practice requires standardized protocols with very low miRNA concentrations, particularly in plasma samples. Here we tested ...
  • Albanell Mestres, Joan; iMolins, A. B.; Martínez, L. C.; López-Muñiiz, J. I. C.; Gil, E. C.; Juan Ferré, A. de; Barco Berrón, S. del; Pérez, Y. F.; Mata, J. G.; Palomo, A. G.; Gregori, J. G.; Pardo, P. G.; Mañas, J. J. I.; Hernández, A. L.; Dueñas-Espín, Iván, 1979-; Jáñez, N. M.; Murillo, S. M.; Bofill, J. S.; Auñón, P. Z.; Sánchez-Rovira, P. (Springer, 2017)
    Metastatic breast cancer is a heterogeneous disease that presents in varying forms, and a growing number of therapeutic options makes it difficult to determine the best choice in each particular situation. When selecting ...
  • Hernández Acosta, Astrid; Baños i Díez, Josep Eladi; Llop, Cristina; Farré Albaladejo, Magí (Public Library of Science (PLoS), 2014)
    Aim: Lack of knowledge concerning the nature of placebo and why it is necessary may influence the participation of patients in clinical trials. The objective of the present study is to review how placebo is described in ...
  • Maurer, Marcus; Metz, Martin; Bindslev-Jensen, Carsten; Bousquet, Jean; Canonica, G. Walter; Church, Martin K.; Godse, Kiran V.; Grattan, Clive; Hide, Michihiro; Kocatürk, Emek; Magerl, M.; Makris, Michael; Meshkova, R. Y.; Saini, Sarbjit S.; Sussman, Gordon; Toubi, Elias; Zhao, Zuotao; Zuberbier, Torsten; Giménez Arnau, Anna Maria (Wiley, 2016)
    BACKGROUND: GA²LEN, the Global Allergy and Asthma European Network, has recently launched a program for the development, interaction, and accreditation of centers of reference and excellence in special areas of allergy ...

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