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Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Issue Date

Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Issue Date

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  • Villanueva, Cristina M.; Silverman, Debra T.; Murta-Nascimento, Cristiane; Malats i Riera, Núria; García Closas, Montserrat; Castro Domínguez, Francisco; Tardón, Adonina; García Closas, Reina; Serra, Consol; Carrato, Alfredo; Rothman, Nathaniel; Real, Francisco X.; Dosemeci, Mustafa; Kogevinas, Manolis (Springer, 2009)
    Objective: We evaluated the bladder cancer risk associated with coffee consumption in a case–control study in Spain and examined the gene–environment interactions for genetic variants of caffeine-metabolizing enzymes. ...
  • Lee, Sing; Tsang, Adley; Ruscio, Ayelet Meron; Haro Abad, Josep Maria; Stein, Dan J.; Alonso Caballero, Jordi; Angermeyer, Matthias C.; Bromet, Evelyn J.; Demyttenaere, Koen; Girolamo, Giovanni de; de Graaf, Ron; Gureje, Oye; Iwata, Noboru; Karam, Elie G.; Lepine, Jean-Pierre; Levinson, Daphna; Medina Mora, Maria Elena; Browne, Mark Oakley; Posada Villa, José; Kessler, Ronald C. (Cambridge University Press, 2009)
    BACKGROUND: A number of western studies have suggested that the 6-month duration requirement of generalized anxiety disorder (GAD) does not represent a critical threshold in terms of onset, course, or risk factors of the ...
  • Kessler, Ronald C.; Aguilar-Gaxiola, Sergio; Alonso Caballero, Jordi; Chatterji, Somnath; Lee, Sing; Ormel, Johan; Üstün, T. Bedirhan; Wang, Philip S. (Il Pensiero Scientifico, 2009)
    AIMS: The paper reviews recent findings from the WHO World Mental Health (WMH) surveys on the global burden of mental disorders. METHODS: The WMH surveys are representative community surveys in 28 countries throughout the ...
  • Nieuwenhuijsen, Mark J.; Martinez Murciano, David; Grellier, James; Bennett, James; Best, Nicky; Iszatt, Nina; Vrijheid, Martine; Toledano, Mireille B. (National Institute of Environmental Health Sciences (NIEHS), 2009)
    OBJECTIVES: The aim of this study was to review epidemiologic evidence, provide summary risk estimates of the association between exposure to chlorination disinfection by-products (DBPs) and congenital anomalies, and provide ...
  • Huang, An-Tsun; Kogevinas, Manolis; Silverman, Debra T.; Malats i Riera, Núria; Rothman, Nathaniel; Tardón, Adonina; Serra, Consol; García Closas, Reina; Carrato, Alfredo; Cantor, Kenneth P (Springer, 2009)
    Hormonal factors, possibly related to reproductive characteristics, may play a role in the risk of bladder cancer among women. To study this, we investigated the effects of reproductive factors on female bladder cancer ...
  • Castro Giner, Francesc; Künzli, Nino; Jacquemin Leonard, Bénédicte; Forsberg, Bertil; Cid Ibeas, Rafael de; Sunyer Deu, Jordi; Jarvis, Deborah; Briggs, David; Vienneau, Danielle; Norbäck, Dan; Gonzalez, Juan Ramon; Guerra, Stefano; Janson, Christer; Antó i Boqué, Josep Maria; Wjst, Matthias; Heinrich, Joachim; Estivill, Xavier, 1955-; Kogevinas, Manolis (National Institute of Environmental Health Sciences (NIEHS), 2009)
    BACKGROUND: Traffic-related air pollution is related with asthma, and this association may be modified by genetic factors. OBJECTIVES: We investigated the role of genetic polymorphisms potentially modifying the association ...
  • Vincent, Theresa; Neve, Etienne P.A.; Johnson, Jill R.; Kukalev, Alexander; Rojo, Federico; Albanell Mestres, Joan; Pietras, Kristian; Virtanen, Ismo; Philipson, Lennart; Leopold, Philip L.; Crystal, Ronald G.; García de Herreros, Antonio; Moustakas, Aristidis; Petterson, Ralf F.; Fuxe, Jonas (Nature Research, 2009)
    Epithelial-mesenchymal transition (EMT) is essential for organogenesis and is triggered during carcinoma progression to an invasive state. Transforming growth factor-beta (TGF-beta) cooperates with signalling pathways, ...
  • Balcells Vilarnau, Eva, 1967-; Antó i Boqué, Josep Maria; Gea Guiral, Joaquim; Gómez, Federico P.; Rodríguez, Esther; Marin, Alicia; Ferrer, Antoni-Lluc, 1942-; De Batlle, Jordi; Farrero, Eva; Benet, Marta; Orozco Levi, Mauricio; Ferrer, Jaume; Agustí, Alvar; Gáldiz, Juan B.; Belda, José; García Aymerich, Judith (Elsevier, 2009)
    BACKGROUND: This study describes the characteristics of a large sample of patients hospitalised for the first time for a chronic obstructive pulmonary disease (COPD) exacerbation. METHODS: All subjects first admitted for ...
  • Korff, Michael von; Alonso Caballero, Jordi; Ormel, Johan; Angermeyer, Matthias C.; Bruffaerts, Ronny; Fleiz, Clara; Girolamo, Giovanni de; Kessler, Ronald C.; Kovess, Viviane; Posada Villa, José; Scott, Kate M.; Uda, Hidenori (Elsevier, 2009)
    Neural, endocrine, and immune stress mediators are hypothesized to increase risks of diverse chronic diseases, including arthritis. Retrospective data from the World Mental Health Surveys (N=18,309) were employed to assess ...
  • Voll-Aanerud, Marianne; Eagan, Thomas ML; Plana, Estel; Omenaas, Ernst R; Bakke, Per S; Svanes, Cecilie; Siroux, Valérie; Pin, Isabelle; Antó i Boqué, Josep Maria; Leynaert, Bénédicte (BioMed Central, 2010)
    Background: Respiratory symptoms are common in the general population, and their presence is related to Health-related quality of life (HRQoL). The objective was to describe the association of respiratory symptoms with ...
  • Estrada, Maria Dolors; Rajmil Rajmil, Luis Alberto; Serra Sutton, Vicky; Tebé, Cristian; Alonso Caballero, Jordi; Herdman, Michael; Riley, Anne W.; Forrest, Christopher B.; Starfield, Barbara (BioMed Central, 2010)
    Background: The objectives of the study were to assess the reliability, and the content, construct, and convergent validity of the Spanish version of the CHIP-CE/PRF, to analyze parent-child agreement, and compare the ...
  • Rebollo, Pablo; Castejón, Ignacio; Cuervo, Jesús; Villa, Guillermo; García-Cueto, Eduardo; Díaz-Cuervo, Helena; Zardain, Pilar C.; Muñiz, José; Alonso Caballero, Jordi; Spanish CAT-Health Research Group (BioMed Central, 2010)
    Background: Health Related Quality of Life (HRQoL) is a relevant variable in the evaluation of health outcomes. Questionnaires based on Classical Test Theory typically require a large number of items to evaluate HRQoL. ...
  • Larriba, María Jesús; Casado Vela, Juan; Pendás Franco, Natalia; Peña, Raúl; García de Herreros, Antonio; Berciano, María Teresa; Lafarga, Miguel; Casal, José Ignacio; Muñoz, Alberto (Public Library of Science (PLoS), 2010)
    Background: The transcription factor Snail1 induces epithelial-to-mesenchymal transition (EMT), a process responsible for the acquisition of invasiveness during tumorigenesis. Several transcriptomic studies have ...
  • Cantor, Kenneth P; Villanueva Belmonte, Cristina; Silverman, Debra T.; Figueroa, Jonine D.; Real, Francisco X.; García Closas, Montserrat; Malats i Riera, Núria; Chanock, Stephen J.; Yeager, Meredith; Tardón, Adonina; García Closas, Reina; Serra, Consol; Carrato, Alfredo; Castaño Vinyals, Gemma; Samanic, Claudine; Rothman, Nathaniel; Kogevinas, Manolis (National Institute of Environmental Health Sciences (NIEHS), 2010)
    Background: Bladder cancer has been linked with long-term exposure to disinfection by-products (DBPs) in drinking water.Objectives: In this study we investigated the combined influence of DBP exposure and polymorphisms in ...
  • Selent, Jana; Sanz, Ferran; Pastor Maeso, Manuel; De Fabritiis, Gianni (Public Library of Science (PLoS), 2010)
    G-protein coupled receptors, the largest family of proteins in the human genome, are involved in many complex signal transduction pathways, typically activated by orthosteric ligand binding and subject to allosteric ...
  • Stein, Dan J.; Alonso Caballero, Jordi; Nock, Matthew K. (Public Library of Science (PLoS), 2010)
    Background: Community and clinical data have suggested there is an association between trauma exposure and suicidal behavior (i.e., suicide ideation, plans and attempts). However, few studies have assessed which traumas ...
  • Rodríguez Santiago, Benjamín; Malats i Riera, Núria; Rothman, Nathaniel; Armengol i Dulcet, Lluís; García Closas, Montserrat; Kogevinas, Manolis; Villa, Olaya; Hutchinson, Amy; Earl, Julie; Marenne, Gaëlle; Jacobs, Kevin; Rico, Daniel; Tardón, Adonina; Carrato, Alfredo; Thomas, Gilles; Valencia, Alfonso; Silverman, Debra T.; Real, Francisco X.; Chanock, Stephen J.; Pérez Jurado, Luis Alberto (Elsevier, 2010)
    Mosaicism is defined as the coexistence of cells with different genetic composition within an individual, caused by postzygotic somatic mutation. Although somatic mosaicism for chromosomal abnormalities is a well-established ...
  • Vilaró Casamitjana, Jordi; Ramírez Sarmiento, Alba; Martínez-Llorens, Juana Mª; Mendoza, Teresa; Álvarez, Miguel; Sánchez Cayado, Natalia; Vega, Ángeles; Gimeno Santos, Elena, 1980-; Coronell Coronell, Carlos Gustavo; Gea Guiral, Joaquim; Roca, Josep; Orozco Levi, Mauricio (Elsevier, 2010)
    Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with several modifiable (sedentary life-style, smoking, malnutrition, hypoxemia) and non-modifiable (age, co-morbidities, severity of pulmonary ...
  • Casagolda, David; Valle Pérez, Beatriz del; Valls, Gabriela; Lugilde, Ero; Vinyoles, Meritxell; Casado Vela, Juan; Solanas, Guiomar; Batlle Gómez, Eduard; Reynolds, Albert B.; Casal, José Ignacio; García de Herreros, Antonio; Duñach, Mireia (Company of Biologists, 2010)
    p120-catenin is an E-cadherin-associated protein that modulates E-cadherin function and stability. We describe here that p120-catenin is required for Wnt pathway signaling. p120-catenin binds and is phosphorylated by CK1ε ...
  • Mokkink, Lidwine B.; Terwee, Caroline B.; Patrick, Donald L.; Alonso Caballero, Jordi; Stratford, Paul W.; Knol, Dirk L.; Bouter, Lex M.; De Vet, Henrica C. W. (Springer, 2010)
    BACKGROUND: Aim of the COSMIN study (COnsensus-based Standards for the selection of health status Measurement INstruments) was to develop a consensus-based checklist to evaluate the methodological quality of studies on ...

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