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Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

Browsing Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)) by Title

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  • Alemany, Silvia; Vilor Tejedor, Natàlia, 1988-; Bustamante Pineda, Mariona; Pujol Martí, Jesús, 1981-; Macià, Dídac; Martínez-Vilavella, Gerard; Fenoll, Raquel; Álvarez Pedrerol, Mar; Forns i Guzman, Joan, 1981-; Júlvez Calvo, Jordi; Suades González, Elisabet; Llop, Sabrina; Rebagliato, Marisa; Sunyer Deu, Jordi (Public Library of Science (PLoS) , 2016)
    BACKGROUND: Attention function filters and selects behaviorally relevant information. This capacity is impaired in some psychiatric disorders and has been proposed as an endophenotype for Attention-Deficit/Hyperactivity ...
  • González Gascón y Marín, Isabel; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Hernández, José-Ángel; Grupo Español de Leucemia Linfática Crónica (GELLC); Grupo Cooperativo Español de Citogenética Hematológica (GCECGH) (Wiley, 2014)
    The prognosis of chronic lymphocytic leukemia (CLL) patients displaying trisomy 12 (+12) remains unclear. In this study, we analyzed the influence of the proportion of cells with +12, and other clinical and biologic factors, ...
  • Iorio, Francesco Iorio; Tamborero Noguera, David; López Bigas, Núria; Esteller, Manel; Garnett, Mathew J. (Elsevier, 2016)
    Systematic studies of cancer genomes have provided unprecedented insights into the molecular nature of cancer. Using this information to guide the development and application of therapies in the clinic is challenging. Here, ...
  • Uffing, Audrey; Pérez-Sáez, María José; Riella, Leonardo V. (BioMed Central, 2018)
    BACKGROUND: Long-term outcomes in kidney transplantation (KT) have not significantly improved during the past twenty years. Despite being a leading cause of graft failure, glomerular disease (GD) recurrence remains poorly ...
  • Pujol Martí, Jesús; Fenoll, Raquel; Ribas-Vidal, Núria; Martínez-Vilavella, Gerard; Blanco Hinojo, Laura, 1981-; Blanco Hinojo, Laura, 1981-; García-Alba, Javier; Deus, Joan; Novell, Ramon; Esteba-Castillo, Susanna (Elsevier, 2018)
    BACKGROUND: We longitudinally assessed Down syndrome individuals at the age of risk of developing dementia to measure changes in brain anatomy and their relationship to cognitive impairment progression. METHODS: Forty-two ...
  • Suades González, Elisabet; Forns i Guzman, Joan, 1981-; García Esteban, Raquel; López Vicente, Mònica, 1988-; Esnaola, Mikel; Álvarez Pedrerol, Mar; Júlvez Calvo, Jordi; Cáceres, Alejandro; Basagaña Flores, Xavier; López-Sala, Anna; Sunyer Deu, Jordi (Frontiers, 2017)
    Background: Prospective longitudinal studies are essential in characterizing cognitive trajectories, yet few of them have been reported on the development of attention processes in children. We aimed to explore attention ...
  • Hernández, José-Ángel; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Hernández-Rivas, Jesús María; Grupo Cooperativo Español de Citogenética Hematológica (GCECGH); Grupo Español de Leucemia Linfática Crónica (GELLC) (Public Library of Science, 2015)
    To analyze the impact of the 11q deleted (11q-) cells in CLL patients on the time to first therapy (TFT) and overall survival (OS), 2,493 patients with CLL were studied. 242 patients (9.7%) had 11q-. Fluorescence in situ ...
  • Pastor, Antonio; Fernández Aranda, Fernando; Fitó Colomer, Montserrat; Jiménez Murcia, Susana; Botella, Cristina; Fernández Real, Jose M.; Frühbeck, Gema; Tinahones Madueño, Francisco José; Fagundo, Ana B.; Rodríguez Rodríguez, Juan Francisco; Agüera, Zaida; Langohr, Klaus; Casanueva, Felipe F.; Torre Fornell, Rafael de la (Public Library of Science , 2016)
    The endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in ...
  • Storniolo, Carolina Emilia; Casillas, Rosario; Bulló, Mònica; Castañer, Olga; Ros, Emilio; Sáez, Guillermo; Toledo, Estefania; Estruch, Ramón; Ruiz-Gutiérrez, Valentina; Fitó Colomer, Montserrat; Martínez-González, Miguel A.; Salas-Salvadó, Jordi; Mitjavila, María Teresa; Moreno, Juan José (Springer, 2017)
    PURPOSE: Serum nitric oxide (NO) reduction and increased endothelin-1 (ET-1) play a pivotal role in endothelial dysfunction and hypertension. Considering that traditional Mediterranean diet (TMD) reduces blood pressure ...
  • Rothman, Nathaniel; Real, Francisco X.; Serra, Consol; Lloreta Trull, Josep, 1958-; Chanock, Stephen J. (Nature Research, 2010)
    We conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a ...
  • Gerdtsson, Anna S.; Malats i Riera, Núria; Säll, Anna; Real, Francisco X.; Porta Serra, Miquel; Skoog, Petter; Persson, Helena; Wingren, Christer; Borrebaeck, Carl A. K. (Hindawi Publishing Corporation, 2015)
    Background. Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with rapid tumor progression and poor prognosis. This study was motivated by the lack of sensitive and specific PDAC biomarkers and aimed to ...
  • Jain, Pooja; Vineis, Paolo; Liquet, Benoît; Vlaanderen, Jelle; Bodinier, Barbara; van Veldhoven, Karin; Kogevinas, Manolis; Athersuch, Toby J.; Font-Ribera, Laia; Villanueva Belmonte, Cristina; Vermeulen, Roel; Chadeau-Hyam, Marc (BMJ Publishing Group, 2018)
    Epidemiological studies provide evidence that environmental exposures may affect health through complex mixtures. Formal investigation of the effect of exposure mixtures is usually achieved by modelling interactions, which ...
  • Hernández-Ruiz, Eugenia; Hernández Muñoz, Inmaculada; Masferrer, Emili; Ferrandiz-Pulido, Carla; Andrades, Evelyn; Gimeno Beltran, Javier; Duran, Xavier; García-Patos, Vicenç; Pujol Vallverdú, Ramon Maria; Toll Abelló, Agustín (Society for Publication of Acta Dermato-Venereologica, 2019)
    Although desmoplasia has been associated with poor prognoses in cutaneous squamous cell carcinoma, little attention has been paid to the patterns of fibrosis. This study aimed to examine the different stromal fibrotic ...
  • Sola Llopis, Susana de; Torre Fornell, Rafael de la; Sánchez Benavides, Gonzalo; Benejam, Bessy; Cuenca Royo, Aida Ma, 1981-; Del Hoyo Soriano, Laura; Rodríguez, Joan; Catuara Solarz, Silvina, 1986-; Sánchez Gutiérrez, Judit; Dueñas-Espín, Iván, 1979-; Hernández, Gimena; Peña-Casanova, J. (Jordi); Langohr, Klaus; Videla, Sebastià; Blehaut, Henry; Farré Albaladejo, Magí; Dierssen, Mara; TESDAD Study Group (Frontiers, 2015)
    The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome (DS) has boosted a number of clinical trials in this population. However, running the trials has raised some methodological ...
  • Szpringer, Monika; Oledzka, Marzena; Amann, Benedikt Lorenz (Frontiers, 2018)
    Glioblastoma multiforme (GBM) is a highly aggressive brain cancer and its survival after diagnosis is less than 2 years. Therefore, GBM patients are especially prone to co-occurring psychological conditions such as anxiety ...
  • Sanchis-Alfonso, Vicente; Tey Pons, Marcos; Monllau García, Juan Carlos (Hindawi Publishing Corporation, 2015)
    Background. For a long time it has been accepted that the main problem in the anterior knee pain (AKP) patient is in the patella. Currently, literature supports the link between abnormal hip function and AKP. Objective. ...
  • Vartia, Salla; Villanueva Cañas, José Luis, 1984-; Finarelli, John; Farrell, Edward D.; Collins, Patrick C.; Hughes, Graham M.; Carlsson, Jeanette E. L.; Gauthier, David T.; McGinnity, Philip; Cross, Thomas F.; FitzGerald, Richard D.; Mirimin, Luca; Crispie, Fiona; Cotter, Paul D.; Carlsson, Jens (Royal Society Publishing, 2016)
    This study examines the potential of next-generation sequencing based 'genotyping-by-sequencing' (GBS) of microsatellite loci for rapid and cost-effective genotyping in large-scale population genetic studies. The recovery ...
  • Jungfleisch, Jennifer, 1986-; Nedialkova, Danny D.; Dotu, Ivan; Sloan, Katherine E.; Martínez Bosch, Neus; Brüning, Lukas; Raineri, Emanuele; Navarro Medrano, Pilar; Bohnsack, Markus T.; Leidel, Sebastian; Díez Antón, Juana, 1962- (Cold Spring Harbor Laboratory Press (CSHL Press), 2017)
    The impact of RNA structures in coding sequences (CDS) within mRNAs is poorly understood. Here, we identify a novel and highly conserved mechanism of translational control involving RNA structures within coding sequences ...
  • Latorre, Irene; Leidinger, Petra; Backes, Christina; Domínguez, Jose; de Souza-Galvao, Malú; Maldonado, Jose; Prat, Cristina; Ruiz, Juan Jesús; Sánchez Martínez, Francisca; Casas, Irma; Keller, Andreas; Briesen, Hagen von; Knobel Freud, Hernando; Meese, Eckart; Meyerhans, Andreas (European Respiratory Society, 2015)
    Background: Deregulation of microRNAs (miRNAs)has been associated with various human pathologies including bacterial infections.Aim: To investigate the role of miRNAs as blood biomarkers for the diagnosis of active pulmonary ...
  • Casagolda, David; Valle Pérez, Beatriz del; Valls, Gabriela; Lugilde, Ero; Vinyoles, Meritxell; Casado Vela, Juan; Solanas, Guiomar; Batlle Gómez, Eduard; Reynolds, Albert B.; Casal, José Ignacio; García de Herreros, Antonio; Duñach, Mireia (Company of Biologists, 2010)
    p120-catenin is an E-cadherin-associated protein that modulates E-cadherin function and stability. We describe here that p120-catenin is required for Wnt pathway signaling. p120-catenin binds and is phosphorylated by CK1ε ...

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