• Altered subcortical emotional salience processing differentiates parkinson's patients with and without psychotic symptoms

  Knolle, Franziska; Garofalo, S.; Viviani, R.; Justicia Díaz, Azucena; Ermakova, Anna O.; Blank, H.; Williams, G.B.; Arrondo, G.; Ramachandra, P.; Tudor-Sfetea, C.; Tudor-Sfetea, C.; Bunzeck, Nico; Düzel, Emrah; Robbins, T.W.; Barker, R.A.; Murray, Graham K. (Elsevier, 2020)

  Objective: Current research does not provide a clear explanation for why some patients with Parkinson's Disease (PD) develop psychotic symptoms. The 'aberrant salience hypothesis' of psychosis has been influential and ...
• Psychiatry in the aftermath of COVID-19

  Vieta, Eduard; Pérez Solá, Victor; Arango, Celso (Elsevier, 2020)
• Articular angioedema in patients with chronic spontaneous urticaria is frequently misdiagnosed as arthritis

  Toubi, Elias; Giménez Arnau, Anna Maria; Maurer, Marcus; Vadasz, Zahava (Elsevier, 2020)
• Influence of age on the occurrence of adverse events in rheumatic patients at the onset of biological treatment: data from the BIOBADASER III registrer

  Vela, Paloma; Sánchez-Piedra, Carlos; Pérez-García, Carolina; Castro-Villegas, María C.; Freire, Mercedes; Mateo, Lourdes; Díaz-Torné, Cesar; Bohórquez, Cristina; Blanco-Madrigal, Juan M.; Ros-Vilamajo, Inmaculada; Gómez, Silvia; Caño, Rocio; Sánchez-Alonso, Fernando; Díaz-González, Federico; Gómez-Reino, Juan J. (BioMed Central, 2020)

  Objectives: To assess whether age, at the beginning of biologic treatment, is associated with the time a first adverse event (AE) appears in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), or psoriatic ...
• Mediterranean diet Effects on type 2 diabetes prevention, disease progression, and related mechanisms. A review

  Martín-Peláez, Sandra; Fitó Colomer, Montserrat; Castañer, Olga (MDPI, 2020)

  The search for a quality diet has grown over the past decade. Diet is considered one of the pillars for the prevention and progression of several diseases, among them: diabetes. Type 2 diabetes (T2D) is an epidemic of ...
• Adherence to the mediterranean lifestyle and desired body weight loss in a mediterranean adult population with overweight: a PREDIMED-Plus Study

  Bouzas, Cristina; Zomeño Fajardo, Maria Dolores; Muñoz, Julia; Castañer, Olga; Goday Arno, Alberto; Tur, J. Antoni (MDPI, 2020)

  Background: Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives: The aim of this study was to assess the association between the adherence ...
• Association between the potential influence of a lifestyle intervention in older individuals with excess weight and metabolic syndrome on untreated household cohabitants and their family support: the PREDIMED-Plus Study

  Basora, Josep; Villalobos, Felipe; Pallejà-Millán, Meritxell; Babio, Nancy; Goday Arno, Alberto; Castañer, Olga; Fitó Colomer, Montserrat; Zomeño Fajardo, Maria Dolores; Pintó Sala, Xavier; Sacanella, Emilio; Paz-Graniel, Indira; Salas Salvadó, Jordi (MDPI, 2020)

  This cross-sectional study aims to evaluate the association between the PREDIMED-Plus study lifestyle intervention and (i) adherence to the Mediterranean diet (MedDiet) and (ii) physical activity of cohabiting study ...
• Satellite cells and markers of muscle regeneration during unloading and reloading: effects of treatment with resveratrol and curcumin

  Mañas-García, Laura; Guitart, Maria; Duran Jordà, Xavier, 1974-; Barreiro Portela, Esther (MDPI, 2020)

  We hypothesized that treatment with pharmacological agents known to increase sirtuin-1 activity (resveratrol and curcumin) may enhance muscle regeneration. In limb muscles of mice (C57BL/6J, 10 weeks) exposed to reloading ...
• Down syndrome is a metabolic disease: altered insulin signaling mediates peripheral and brain dysfunctions

  Dierssen, Mara; Fructuoso, Marta; Martínez de Lagrán Cabredo, María; Perluigi, Marzia; Barone, Eugenio (Frontiers, 2020)

  Down syndrome (DS) is the most frequent chromosomal abnormality that causes intellectual disability, resulting from the presence of an extra complete or segment of chromosome 21 (HSA21). In addition, trisomy of HSA21 ...
• Transcriptomic differences in MSA clinical variants

  Pérez Soriano, Alexandra; Arnal, Magdalena; Botta Orfila, Teresa; Giraldo, Darly; Fernández, Manel; Compta, Yaroslau; Fernández-Santiago, Ruben; Ezquerra, Mario; Tartaglia, Gian Gaetano; Martí, M. Josep; Catalan multiple system atrophy-registry (CMSAR) (Nature Research, 2020)

  Background: Multiple system atrophy (MSA) is a rare oligodendroglial synucleinopathy of unknown etiopathogenesis including two major clinical variants with predominant parkinsonism (MSA-P) or cerebellar dysfunction (MSA-C). ...
• COVID-19 y la neumología del siglo XXI: ¿reto u oportunicad?

  Barreiro Portela, Esther; Jiménez, Carlos; García de Pedro, Julia; Ramírez Prieto, María Teresa (Elsevier, 2020)
• Correction: use of health apps by nurses for professional purposes: web-based survey study

  Mayer, Miguel Ángel, 1960- (JMIR Publications Inc., 2019)
• Improved diagnosis of rare disease patients through systematic detection of runs of homozygosity

  Matalonga, Leslie; Laurie, Steven; Papakonstantinou, Anastasios; Piscia, Davide; Mereu, Elisabetta; Bullich, Gemma; Thompson, Rachel; Horvath, Rita; Pérez Jurado, Luis Alberto; Riess, Olaf; Gut, Ivo; van Ommen, Gert-Jan; Lochmüller, Hanns; Beltran, Sergi; RD–Connect Genome-Phenome Analysis Platform and URD-Cat Data Contributors (Elsevier, 2020)

  Autozygosity is associated with an increased risk of genetic rare disease, thus being a relevant factor for clinical genetic studies. More than 2400 exome sequencing data sets were analyzed and screened for autozygosity ...
• Bioavailability of epigallocatechin gallate administered with different nutritional strategies in healthy volunteers

  Andreu-Fernández, Vicente; Almeida Toledano, Laur; Pizarro Lozano, Mª Nieves; Navarro-Tapia, Elisabet; Gómez-Roig, María Dolores; Torre Fornell, Rafael de la; García-Algar, Oscar (MDPI, 2020)

  The flavanol epigallocatechin gallate (EGCG) is being tested for the treatment of several diseases in humans. However, its bioavailability and pharmacokinetic profile needs a better understanding to enable its use in ...
• Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

  Milà Alomà, Marta; Salvadó, Gemma; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; Grau-Rivera, Oriol; Sala Vila, Aleix; Sánchez Benavides, Gonzalo; Arenaza Urquijo, Eider M.; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Molinuevo, José Luis; ALFA Study (Wiley, 2020)

  Introduction: The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. Methods: We used NeuroToolKit and Elecsys® immunoassays to measure cerebrospinal fluid (CSF) ...
• ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)

  Bousquet, Jean; Antó i Boqué, Josep Maria; Agache, Ioana (Wiley, 2020)
• Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: the ENIGMA adventure

  Hoogman, Martine; Vilarroya, Óscar; Franke, Barbara (Wiley, 2020)

  Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main ...
• Epigenomic assessment of cardiovascular disease risk and interactions with traditional risk metrics

  Westerman, Kenneth; Fernández Sanlés, Alba; Patil, Prasad; Sebastiani, Paola; Jacques, Paul; Starr, John M.; Deary ,Ian J.; Liu, Qing; Liu, Simi; Elosua Llanos, Roberto; DeMeo, Dawn L; Ordovás, José M. (Wiley-Blackwell, 2020)

  Background Epigenome-wide association studies for cardiometabolic risk factors have discovered multiple loci associated with incident cardiovascular disease (CVD). However, few studies have sought to directly optimize a ...
• Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

  Zeitlinger, Markus; Koch, Birgit C.P.; Bruggemann, Roger; De Cock, Pieter; Felton, Timothy; Hites, Maya; El, Jennifer; Luque Pardos, Sònia; MacGowan, Alasdair P.; Marriott, Deborah J. E.; Muller, Anouk E.; Nadrah, Kristina; Paterson, David L.; Standing, Joseph F.; Telles, João P.; Wölfl-Duchek, Michael; Thy, Michael; Roberts, Jason A.; PK/PD of Anti-Infectives Study Group (EPASG) of the European Society of Clinical Microbiology, Infectious Diseases (ESCMID) (SpringerOpen, 2020)

  There is an urgent need to identify optimal antiviral therapies for COVID-19 caused by SARS-CoV-2. We have conducted a rapid and comprehensive review of relevant pharmacological evidence, focusing on (1) the pharmacokinetics ...
• NeuroHeal reduces muscle atrophy and modulates associated autophagy

  Marmolejo-Martínez-Artesero, Sara; Romeo-Guitart, David; Mañas-García, Laura; Barreiro Portela, Esther; Casas, Caty (MDPI, 2020)

  Muscle wasting is an unmet medical need which leads to a reduction of myofiber diameter and a negative impact on the functional performance of daily activities. We previously found that a new neuroprotective drug called ...

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