• Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: study protocol of a multinational observational study

  Hagens, Eliza R. C.; Pera Roman, Manuel Ramón; Gisbertz, Suzanne S. (BioMed Central, 2019)

  BACKGROUND: An important parameter for survival in patients with esophageal carcinoma is lymph node status. The distribution of lymph node metastases depends on tumor characteristics such as tumor location, histology, ...
• A rare case of right lower quadrant pain

  Teiga, Eduardo; Radosevic, Aleksandar; Sánchez Parrila, Juan; Busto Barrera, Marcos; Aguilar Sánchez, Guadalupe; Maiques LLacer, José María; Flores Pereyra, Daniel; Zugazaga Cortázar, Ander; Gimeno Beltran, Javier; Bazán, Fernando (British Institute of Radiology, 2018)

  Endometriosis of the appendix is a very rare entity and commonly affects females in childbearing age. Clinical presentation might be confusing varying from asymptomatic to acute abdominal pain and often mimicks acute ...
• Hepatic encephalopathy resulting in mania, a possible role of bilirubin and glutamate?

  Mortier, Philippe; Tu, Hanna; Van Walleghem, Dominique; Wyckaert, Sabine; Sienaert, Pascal (Wiley-Blackwell, 2019)
• Enabling green and blue infrastructure to improve contributions to human well-being and equity in urban systems

  Andersson, Erik; Langemeyer, Johannes; Borgström, Sara; McPhearson, Timon; Haase, Dagmar; Kronenberg, Jakub; Barton, David N.; Davis, McKenna; Naumann, Sandra; Röschel, Lina; Baró Porras, Francesc (Oxford University Press, 2019)

  The circumstances under which different ecosystem service benefits can be realized differ. The benefits tend to be coproduced and to be enabled by multiple interacting social, ecological, and technological factors, which ...
• Automatic glaucoma classification using color fundus images based on convolutional neural networks and transfer learning

  Gómez-Valverde, Juan J.; Antón López, Alfonso; Fatti, Gianluca; Liefers, Bart; Herranz, Alejandra; Santos, Andrés; Sánchez, V.; Ledesma-Carbayo, María J. (Optical Society of America (OSA), 2019)

  Glaucoma detection in color fundus images is a challenging task that requires expertise and years of practice. In this study we exploited the application of different Convolutional Neural Networks (CNN) schemes to show the ...
• Testing the effects of gentle vibrotactile stimulation on symptom relief in fibromyalgia

  Pujol Nuez, Jesús; Ramos-López, Daniel; Blanco Hinojo, Laura, 1981-; Pujol, Guillem; Ortiz, Héctor; Martínez-Vilavella, Gerard; Blanch Rubio, Josep; Monfort Faure, Jorge; Deus, Joan (BioMed Central, 2019)

  BACKGROUND: Sensory disturbances in fibromyalgia extend beyond nociception. It has been proposed that imbalance in the mutual competition between painful input and non-painful sensory activity may, to a significant extent, ...
• The impact of hip fracture on health-related quality of life and activities of daily living: the SPARE-HIP prospective cohort study

  Prieto-Alhambra, Daniel; Nogués Solán, Xavier; Díez Pérez, Adolfo (SpringerOpen, 2019)

  PURPOSE: The medical morbidity and mortality associated with neck of femur fractures is well-documented, whereas there is limited data for patient-reported outcomes. The aim of this study was to characterize the impact of ...
• GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

  Couto Alves, Alexessander; Estivill, Xavier, 1955-; Sunyer Deu, Jordi; Early Growth Genetics (EGG) Consortium (American Association for the Advancement of Science (AAAS), 2019)

  Early childhood growth patterns are associated with adult health, yet the genetic factors and the developmental stages involved are not fully understood. Here, we combine genome-wide association studies with modeling of ...
• Factores sociodemográficos y laborales relacionados con la exposición laboral a riesgos psicosociales por ocupación en España. Proyecto MatEmESp.

  González-Galarzo, M. Carmen; Ronda-Pérez, Elena; Benavides, Fernando G. (Fernando García); García, Ana M. (Societat Catalana de Salut Laboral, 2019)

  Objetivo: El objetivo del estudio es describir el nivel de exposición a riesgos psicosociales por ocupación en población laboral española y analizar su relación con condiciones de empleo y características sociodemográficas. ...
• ctDNA to detect minimal residual disease in pancreatic cancer: moving into clinical trials

  Montagut Viladot, Clara; Vidal Barrull, Joana (Oxford University Press, 2019)
• Thromboembolic events in polycythemia vera

  Griesshammer, Martin; Kiladjian, Jean-Jacques; Besses Raebel, Carles (SpringerOpen, 2019)

  Thromboembolic events and cardiovascular disease are the most prevalent complications in patients with polycythemia vera (PV) compared with other myeloproliferative disorders and are the major cause of morbidity and mortality ...
• Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

  Bousquet, Jean; Antó i Boqué, Josep Maria; García Aymerich, Judith; MASK study group (BioMed Central, 2019)

  Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the ...
• Association of maternal iodine status with child IQ: a meta-analysis of individual participant data

  Levie, Deborah; Korevaar, Tim I. M.; Bath, Sarah C.; Murcia, Mario; Dineva, Mariana; Llop, Sabrina; Espada, Mercedes; van Herwaarden, Antonius E.; de Rijke, Yolanda B.; Ibarluzea, Jesús; Sunyer Deu, Jordi; Tiemeier, Henning; Rayman, Margaret P.; Guxens Junyent, Mònica; Peeters, Robin P. (Oxford University Press, 2019)

  Context: Although the consequences of severe iodine deficiency are beyond doubt, the effects of mild to moderate iodine deficiency in pregnancy on child neurodevelopment are less well established. Objective: To study the ...
• Reconstruction of apo A2A receptor activation pathways reveal ligand-competent intermediates and state-dependent cholesterol hotspots

  Lovera, Silvia; Cuzzolin, Alberto; Kelm, Sebastian; De Fabritiis, Gianni; Sands, Zara A. (Nature Research, 2019)

  G-protein coupled receptors (GPCRs) play a pivotal role in transmitting signals at the cellular level. Structural insights can be exploited to support GPCR structure-based drug discovery endeavours. Despite advances in ...
• Maternal circulating Vitamin D3 levels during pregnancy and behaviour across childhood

  López Vicente, Mònica, 1988-; Sunyer Deu, Jordi; Lertxundi, Nerea; González, Llúcia; Rodríguez Dehli, Cristina; Espada Sáenz-Torre, Mercedes; Vrijheid, Martine; Tardón, Adonina; Llop, Sabrina; Torrent Quetglas, Maties; Ibarluzea, Jesús; Guxens Junyent, Mònica (Nature Research, 2019)

  Vitamin D deficiency during critical periods of development could lead to persistent brain alterations. We aimed to assess the association between maternal vitamin D3, the major circulatory form of vitamin D, at pregnancy ...
• Novel P397S MAPT variant associated with late onset and slow progressive frontotemporal dementia

  Borrego-Ecija, Sergi; Antonell Boixader, Anna; Puig-Butille, Joan Anton; Pericot, Inmaculada; Prat-Bravo, Carme; Abellan-Vidal, María Teresa; Mallada, Javier; Olives, Jaume; Falgas, Neus; Oliva, Rafael; Lladó, Albert; Sanchez-Valle, Raquel (American Neurological Association, 2019)

  Mutations in the MAPT gene cause frontotemporal dementia with tau deposits. We report the novel p.P397S MAPT variant in eight subjects from five apparently nonrelated families suffering from frontotemporal dementia with ...
• Role of ADAM17 in kidney disease

  Palau González, Vanesa; Pascual Santos, Julio; Soler, María José; Riera Oliva, Marta (American Physiological Society, 2019)

  It is known that the renin-angiotensin system plays a major role in the pathophysiology of cardiovascular disease and renal injury. Within the renin-angiotensin system, angiotensin-converting enzyme 2 (ACE2) cleaves ANG ...
• Radiofrequency echographic multi-spectrometry for the in-vivo assessment of bone strength: state of the art-outcomes of an expert consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)

  Diez-Perez, Adolfo; Thierry, Thomas (SpringerOpen, 2019)

  PURPOSE: The purpose of this paper was to review the available approaches for bone strength assessment, osteoporosis diagnosis and fracture risk prediction, and to provide insights into radiofrequency echographic multi ...
• Algorithm for the se of biochemical markers of bone turnover in the diagnosis, assessment and follow-up of treatment for osteoporosis

  Lorentzon, Mattias; Díez Pérez, Adolfo; Cavalier, Etienne (Springer, 2019)

  INTRODUCTION: Increased biochemical bone turnover markers (BTMs) measured in serum are associated with bone loss, increased fracture risk and poor treatment adherence, but their role in clinical practice is presently ...
• Management of adult patients with primary immune thrombocytopenia (ITP) in clinical practice: a consensus approach of the Spanish ITP expert group

  Mingot-Castellano, M. Eva; Álvarez Román, M. Teresa; Fernández Fuertes, Luis Fernando; González-López, Tomás José; Guinea de Castro, José María; Jarque, Isidro; López-Fernández, M. Fernanda; Lozano, Maria Luisa; Sanchez Gonzalez, Blanca; Valcárcel Ferreiras, David; González Porras, José Ramón (Hindawi, 2019)

  BACKGROUND AND OBJECTIVE: Diagnosis and management of primary immune thrombocytopenia (ITP) have changed dramatically in the last decade. The aim of the study was to obtain information about the opinion of the Spanish ITP ...

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