• Extensive post-transcriptional buffering of gene expression in the response to severe oxidative stress in baker's yeast

  Blevins, William R.; Tavella, Teresa; Moro, Simone G.; Blasco Moreno, Bernat, 1986-; Closa-Mosquera, Adrià; Díez Antón, Juana, 1962-; Carey, Lucas; Albà Soler, Mar (Nature Research, 2019)

  Cells responds to diverse stimuli by changing the levels of specific effector proteins. These changes are usually examined using high throughput RNA sequencing data (RNA-Seq); transcriptional regulation is generally assumed ...
• Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

  Chauhan, Ganesh; Jiménez-Conde, Jordi; Debette, Stéphanie (Lippincott Williams & Wilkins, 2019)

  OBJECTIVE: To explore genetic and lifestyle risk factors of MRI-defined brain infarcts (BI) in large population-based cohorts. METHODS: We performed meta-analyses of genome-wide association studies (GWAS) and examined ...
• Multicenter study of parenteral nutrition in non-critically ill elderly patients compared to younger patients - Study IAIOS-PN (Incidence and Assessment of Iatrogenesis in Older Subjects receiving Parenteral Nutrition)

  Mateu de Antonio, Francisco Javier; Berlana, David; Pons-Busom, Montserrat; Badia-Tahull, Maria B.; Miana-Mena, María Teresa; Martínez-Castro, Beatriz; Sunyer-Esquerrà, Neus; Sanmartin-Suñer, Mónica; González-Valdivieso, Juan; Leiva-Badosa, Elisabet; Martínez-Bernabé, Eva; Murgadella-Sancho, Anna; Mirerachs-Aranda, Nuria; Vila-Bundó, Anna; Fernández-Morató, Jordi; Vitales-Farrero, María Teresa (Editor de càrrega, 2018)

  OBJECTIVE: this study assessed the incidence of hyperglycemia, hypertriglyceridemia, and liver function test (LFT) alterations among patients older and younger than 65 years receiving parenteral nutrition (PN). A secondary ...
• Trajectories of sickness absence among salaried workers: evidence from the WORKss cohort in Catalonia (Spain), 2012-2014

  Ubalde López, Mònica, 1972-; Hernando-Rodriguez, Julio C.; Benavides, Fernando G. (Fernando García); Serra Saurina, Laura (BMJ Publishing Group, 2019)

  Objectives: Sickness absence (SA) is a widely studied integrated measure of health status. To better understand how SA behaves over time (SA trajectory) a longitudinal and individual-centred approach will allow identifying ...
• Relationship between the respiratory microbiome and the severity of airflow limitation, history of exacerbations and circulating eosinophils in COPD patients

  Millares, Laura; Pascual Guàrdia, Sergi, 1979-; Montón, Concepción; García-Nuñez, Marian; Lalmolda, Cristina; Faner, Rosa; Casadevall Fusté, Carme; Setó, Laia; Capilla, Silvia; Moreno, Amàlia; Castro-Acosta, Ady Angélica; Alvarez-Martinez, Carlos José; Sibila, Oriol; Peces-Barba, Germán; Cosio, Borja G.; Agustí, Alvar; Gea Guiral, Joaquim; Monsó, Eduard (BioMed Central, 2019)

  Background: The respiratory microbiome is altered in COPD patients but its relationship with core components of the disease, such as the severity of airflow limitation, the frequency of exacerbations or the circulating ...
• The role of socioeconomic status in the association of lung function and air pollution-A pooled analysis of three adult ESCAPE cohorts

  Keidel, Dirk; Antó i Boqué, Josep Maria; Basagaña Flores, Xavier; Burte, Marthe-Emilie, 1989-; Carsin, Anne-Elie; Sunyer Deu, Jordi; Jacquemin Leonard, Bénédicte; Probst-Hensch, Nicole (MDPI, 2019)

  Ambient air pollution is a leading environmental risk factor and its broad spectrum of adverse health effects includes a decrease in lung function. Socioeconomic status (SES) is known to be associated with both air pollution ...
• Restrictive spirometry pattern is associated with low physical activity levels. A population based international study

  Carsin, Anne-Elie; Fuertes, Elaine; Antó i Boqué, Josep Maria; Guerra, Stefano; García Aymerich, Judith (Elsevier, 2019)

  Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with ...
• Effects of virgin olive oils differing in their bioactive compound contents on biomarkers of oxidative stress and inflammation in healthy adults: a randomized double-blind controlled trial

  Sánchez-Rodriguez, Estefanía; Biel-Glesson, Sara; Fernández-Navarro, Jose-Ramón; Calleja, Miguel Angel; Espejo-Calvo, Juan A.; Gil-Extremera, Blas; Torre Fornell, Rafael de la; Fitó Colomer, Montserrat; Covas Planells, Maria Isabel; Vilchez, Pedro; Alche, Juan de Dios; Martínez de Victoria, Emilio; Gil, Angel; Mesa, Maria-Dolores (MDPI, 2019)

  A regular consumption of virgin olive oil (VOO) is associated with a reduced risk of cardiovascular disease. We aimed to assess whether the raw intake of an optimized VOO (OVOO, 490 ppm of phenolic compounds and 86 ppm of ...
• Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis

  Gruzieva, Olena; Kogevinas, Manolis; Ruiz, José L.; Bustamante Pineda, Mariona; Antó i Boqué, Josep Maria; Sunyer Deu, Jordi; Vrijheid, Martine; Hernandez-Ferrer, Carles, 1987-; Melén, Erik (National Institute of Environmental Health Sciences (NIEHS), 2019)

  BACKGROUND: Prenatal exposure to air pollution has been associated with childhood respiratory disease and other adverse outcomes. Epigenetics is a suggested link between exposures and health outcomes. OBJECTIVES: We aimed ...
• Urine metabolic signatures of multiple environmental pollutants in pregnant women: an exposome approach

  Maitre, Léa; Robinson, Oliver; Martínez, David; Toledano, Mireille B.; Ibarluzea, Jesús; Marina, Loreto Santa; Sunyer Deu, Jordi; Villanueva, Cristina M.; Keun, Hector C.; Vrijheid, Martine; Coen, Muireann (American Chemical Society (ACS), 2018)

  Exposure to environmental pollutants, particularly during pregnancy, can have adverse consequences on child development but little is known about the effects of pollutant mixtures on endogenous metabolism in pregnant women. ...
• Long-term exposure to residential green and blue spaces and anxiety and depression in adults: A cross-sectional study

  Gascon Merlos, Mireia, 1984-; Sánchez Benavides, Gonzalo; Dadvand, Payam; Martínez, David; Gramunt Fombuena, Nina; Gotsens, Xavier; Cirach, Marta; Vert, Cristina; Molinuevo, José Luis; Crous-Bou, Marta; Nieuwenhuijsen, Mark J. (Elsevier, 2018)

  Background: Although exposure to natural outdoor environments has been consistently associated with improved perceived general health, available evidence on a protective association between this exposure and specific mental ...
• Long-term exposure to trihalomethanes in drinking water and breast cancer in the Spanish multicase-control study on cancer (MCC-SPAIN)

  Font Ribera, Laia; Gràcia Lavedan, Esther; Castaño Vinyals, Gemma; Kogevinas, Manolis; Villanueva, Cristina M. (Elsevier, 2018)

  Background: Exposure to trihalomethanes (THMs) in drinking water has consistently been associated with an increased risk of bladder cancer, but evidence on other cancers including the breast is very limited. Objectives: ...
• Drinking water disinfection by-products during pregnancy and child neuropsychological development in the INMA Spanish cohort study

  Villanueva, Cristina M.; Gracia Lavedan, Esther; Julvez, Jordi; Santa Marina, Loreto; Lertxundi, Nerea; Ibarluzea, Jesús; Llop, Sabrina; Ballester Díez, Ferran; Fernández Somoano, Ana; Tardón, Adonina; Vrijheid, Martine; Guxens Junyent, Mònica; Sunyer Deu, Jordi (Elsevier, 2018)

  Background: Disinfection by-products (DBPs) constitute a complex mixture of prevalent chemicals in drinking water and there is evidence of neurotoxicity for some of them. Objectives: We evaluated the association between ...
• Current controversies in the stepping up and stepping down of inhaled therapies for COPD at the patient level

  Lopez-Campos, Jose Luis; Carrasco Hernández, Laura; Muñoz, Xavier; Bustamante, Víctor; Barreiro Portela, Esther (Wiley, 2018)

  The implementation of potential new step-up or step-down treatment recommendations in response to current guidelines is one of the main challenges currently faced in actual daily practice settings. In the present narrative ...
• Reply to «Influenza vaccination and critical patient protection: responsibility of healthcare workers»

  Marin Corral, Judith; Muñoz Bermudez, Rosana; Álvarez Lerma, Francisco (Elsevier, 2019)
• Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer

  Walsh, Naomi; Porta Serra, Miquel; Real, Francisco X.; Stolzenberg-Solomon, Rachael Z. (Oxford University Press, 2018)

  Genome-wide association studies (GWAS) identify associations of individual single-nucleotide polymorphisms (SNPs) with cancer risk but usually only explain a fraction of the inherited variability. Pathway analysis of genetic ...
• Rituximab treatment Of Pemphigus Foliaceus- A Retrospective Study Of 12 Patients

  Palacios-Álvarez, Irene; Riquelme-Mc Loughlin, Constanza; Curto-Barredo, Laia; Iranzo, Pilar; García-Díez, Irene; España, Agustín (Elsevier, 2018)
• Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial

  Jiménez-Marrero, Santiago; Yun, Sergi; Cainzos-Achirica, Miguel; Enjuanes Grau, Cristina; Garay, Alberto; Farré López, Núria; Verdú-Rotellar, José María; Linas Alonso, Ana Maria; Ruiz-Rodriguez, María del Pilar; Hidalgo, Encarnacion; Calero; Esther; Comín Colet, Josep (SAGE Publications, 2018)

  Background The efficacy of telemedicine in the management of patients with chronic heart failure and left ventricular ejection fraction ≥40% is poorly understood. The aim of our analysis was to evaluate the efficacy of a ...
• Residential proximity to green spaces and breast cancer risk: The multicase-control study in Spain (MCC-Spain)

  O'Callaghan Gordo, Cristina; Kogevinas, Manolis; Cirach, Marta; Castaño Vinyals, Gemma; Gràcia Lavedan, Esther; Espinosa Díaz, Ana; Valentín, Antònia; Nieuwenhuijsen, Mark J. (Elsevier, 2018)

  Background: Breast cancer is the main cause of cancer mortality among women. Green spaces have been recently associated with reduced cancer mortality among women. Mechanisms explaining the beneficial effect of green spaces ...
• Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete)

  O’Callaghan-Gordo, Cristina; Kogevinas, Manolis; Pedersen, Marie; Espinosa Díaz, Ana; Tsiapa, Xristina; Romaguera Bosch, Dora; Chatzi, Leda (Springer, 2018)

  Purpose: The study assessed whether diet and adherence to cancer prevention guidelines during pregnancy were associated with micronucleus (MN) frequency in mothers and newborns. MN is biomarkers of early genetic effects ...

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