• Response-adapted treatment with rituximab, bendamustine, mitoxantrone, and dexamethasone followed by rituximab maintenance in patients with relapsed or refractory follicular Llymphoma after first-line immunochemotherapy: results of the RBMDGELTAMO08 phase II trial

  Peñalver, Francisco-Javier; Márquez, José-Antonio; Durán, Soledad; Giraldo, Pilar; Martin, Alejandro; Montalbán, Carlos; Sancho, Juan Manuel; Ramírez, María-José; Terol, María-José; Capote, Francisco-Javier; Gutiérrez, Antonio; Sánchez González, Blanca; López, Andrés; Salar Silvestre, Antonio; Rodríguez-Caravaca, Gil; Canales, M.; Caballero, María Dolores; GELTAMO group (Wiley, 2019)

  Background: Consensus is lacking regarding the optimal salvage therapy for patients with follicular lymphoma who relapse after or are refractory to immunochemotherapy. Methods: This phase II trial evaluated the efficacy ...
• Green spaces and mortality: a systematic review and meta-analysis of cohort studies

  Rojas Rueda, David, 1979-; Nieuwenhuijsen, Mark J.; Gascon Merlos, Mireia, 1984-; Pérez-León, Daniela; Mudu, Pierpaolo (Elsevier, 2019)

  Background: Green spaces have been proposed to be a health determinant, improving health and wellbeing through different mechanisms. We aimed to systematically review the epidemiological evidence from longitudinal studies ...
• Determinants of study completion and response to a 12-month behavioral physical activity intervention in chronic obstructive pulmonary disease: A cohort study

  Koreny, Maria; Demeyer, Heleen; Arbillaga Etxarri, Ane, 1986-; Gimeno Santos, Elena, 1980-; Barberan-Garcia, Anael; Benet, Marta; Balcells Vilarnau, Eva, 1967-; Borrell, Eulàlia; Marin, Alicia; Rodríguez Chiaradía, Diego A.; Vall-Casas, Pere; Vilaró Casamitjana, Jordi; Rodríguez Roisin, Robert; García Aymerich, Judith (Public Library of Science (PLoS), 2019)

  Objectives: Physical activity is key to improve the prognosis of chronic obstructive pulmonary disease (COPD). To help to tailor future interventions we aimed to identify the baseline characteristics of COPD patients which ...
• Multidisciplinary consensus statement on the clinical management of patients with stage III non-small cell lung cancer

  Majem, Margarita; Hernández-Hernández, J.; Hernando-Trancho, F.; Rodríguez de Dios, Núria; Sotoca, A.; Trujillo-Reyes, J.C.; Vollmer, I.; Delgado-Bolton, R.; Provencio, Mariano (Springer, 2020)

  Stage III non-small cell lung cancer (NSCLC) is a very heterogeneous disease that encompasses patients with resected, potentially resectable and unresectable tumours. To improve the prognostic capacity of the TNM classification, ...
• Association of inflammatory markers with hearing impairment: the english longitudinal study of ageing

  Lassale, Camille; Vullo, Pierluigi; Cadar, Dorina; Batty, G. David; Steptoe, Andrew; Zaninotto, Paola (Elsevier, 2020)

  Background: Hearing impairment is common at an older age and has considerable social, health and economic implications. With an increase in the ageing population, there is a need to identify modifiable risk factors for ...
• Partial loss of USP9X function leads to a male neurodevelopmental and behavioral disorder converging on transforming growth factor β signaling

  Johnson, Brett V.; Pérez Jurado, Luis Alberto; Jolly, Lachlan A. (Elsevier, 2020)

  Background: The X-chromosome gene USP9X encodes a deubiquitylating enzyme that has been associated with neurodevelopmental disorders primarily in female subjects. USP9X escapes X inactivation, and in female subjects de ...
• No se debe empezar la casa por el tejado (si queremos publicar en una revista de impacto)

  Santibáñez, Miguel; García-Rivero, Juan Luis; Barreiro Portela, Esther (Elsevier, 2020)
• Temporal and geographical variability of prevalence and incidence of autism spectrum disorder diagnoses in children in Catalonia, Spain

  Pérez Crespo, Laura; Prats Uribe, Albert; Tobias, Aurelio; Duran-Tauleria Enric; Coronado, Ricard; Hervás, Amaia; Guxens Junyent, Mònica (Wiley, 2019)

  This study aims to estimate the prevalence of autism spectrum disorders (ASD) in 2017 and the ASD diagnosis incidence between 2009 and 2017 in children living in Catalonia region in Spain, and their temporal and geographical ...
• Hypermetabolic bone on 18 F-FDG-PET/CT in a patient with lung cancer: is it always metastasis?

  Martín-Ontiyuelo, Clara; Sánchez Font, Albert; Gimeno Vázquez, Eva; Suárez-Piñera, Marina; Curull Serrano, Víctor (Elsevier, 2020)
• A multidisciplinary proposal for a diagnostic algorithm in idiopathic pulmonary fibrosis: the role of transbronchial cryobiopsy

  Castillo, Diego; Sánchez-Font, Albert; Pajares, Virginia; Franquet, Tomás; Llatjós, Roger; Sansano, Irene; Sellarés, Jacobo; Centeno, Carmen; Fibla, Juan J.; Sánchez, Marcelo; Ramírez, José; Moreno, Amalia; Trujillo-Reyes, Juan Carlos; Barbeta, Enric; Molina-Molina, María; Torrego, Alfons; CRIOMPID (Elsevier, 2020)

  The diagnosis of idiopathic pulmonary fibrosis (IPF) is a complex process that requires the multidisciplinary integration of clinical, radiological, and histological variables. Due to its diagnostic yield, surgical lung ...
• Response to comment on "pancreatoduodenectomy: still an open race for a gold standard?"

  Poves Prim, José Ignacio (Lippincott Williams & Wilkins, 2019)
• Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up

  Fradet, Y.; Bellmunt Molins, Joaquim; Bajorin, D.F. (Elsevier, 2019)

  Background: Novel second-line treatments are needed for patients with advanced urothelial cancer (UC). Interim analysis of the phase III KEYNOTE-045 study showed a superior overall survival (OS) benefit of pembrolizumab, ...
• Biomarkers and clinical characteristics of autoimmune chronic spontaneous urticaria: results of the PURIST study

  Schoepke, Nicole; Giménez Arnau, Anna Maria; Maurer, Marcus (Wiley, 2019)

  Background: Autoimmune chronic spontaneous urticaria (aiCSU) is an important subtype of chronic spontaneous urticaria (CSU) in which functional IgG autoantibodies to IgE or its high-affinity receptor (FcεRI) induces mast ...
• Long-term stroke recurrence after transient ischemic attack: implications of etiology

  Ois Santiago, Angel Javier; Cuadrado Godia, Elisa; Giralt-Steinhauer, Eva; Jiménez Conde, Jordi; Soriano Tarraga, Carolina; Rodríguez Campello, Ana María; Avellaneda Gómez, Carla; Cascales Lahoz, Diego; Fernández-Pérez, Isabel; Roquer, Jaume (Korean Stroke Society, 2019)

  Background and purpose: To analyze long-term stroke recurrence (SR) characteristics after transient ischemic attack (TIA) according to initial etiological classification. Methods: A prospective cohort of 706 TIA patients ...
• Do we really allow patient decision-making in rotator cuff surgery? a prospective randomized study

  Torrens Cánovas, Carlos; Miquel, J.; Santana Pérez, Fernando (BioMed Central, 2019)

  Background: There is a growing patient interest in being involved in the decision-making process. However, little information is provided on how this information should be structured. Does it make a difference, in patient ...
• Evaluation of the effectiveness of hip and knee implant models used in Catalonia: a protocol for a prospective registry-based study

  Arias-de la Torre, Jorge; Domingo Torrell, Laia; Martínez, Olga; Muñoz, Laura; Robles, Noemí; Puigdomènech, Elisa; Pons-Cabrafiga, Miquel; Pallisó, Francesc; Mora, Xavier; Espallargues, Mireia (BioMed Central, 2019)

  Background: Monitoring results regarding the effectiveness of knee and hip arthroplasties may be useful at the clinical, economic and patient level and help reduce the number of prosthesis revisions. In Spain, and specifically ...
• Long-term epigenetic changes in offspring mice exposed to alcohol during gestation and lactation

  Cantacorps, Lídia; Alfonso-Loeches, Silvia; Guerri, Consuelo; Valverde Granados, Olga (SAGE Publications, 2019)

  Background: Alcohol exposure impairs brain development and leads to a range of behavioural and cognitive dysfunctions, termed as foetal alcohol spectrum disorders. Although different mechanisms have been proposed to ...
• Histone deacetylases inhibitor trichostatin A reverses anxiety-like symptoms and memory impairments induced by maternal binge alcohol drinking in mice

  Montagud-Romero, Sandra; Cantacorps, Lídia; Valverde Granados, Olga (SAGE Publications, 2019)

  Background: Alcohol exposure during development has detrimental effects, including a wide range of physical, cognitive and neurobehavioural anomalies known as foetal alcohol spectrum disorders. However, alcohol consumption ...
• A critical time window for recovery extends beyond one-year post-stroke

  Rubio Ballester, Belén; Maier Martina; Maier, Martina; Duff, Amin; Cameirão, Mónica; Bermúdez, Sergi; Duarte Oller, Esther; Cuxart, Ampar; Rodriguez, Susana; San Segundo Mozo, Rosa María; Verschure, Paul F. M. J. (American Physiological Society, 2019)

  The impact of rehabilitation on post-stroke motor recovery and its dependency on the patient's chronicity remain unclear. The field has widely accepted the notion of a proportional recovery rule with a "critical window for ...
• Genetic factors contributing to autism spectrum disorder in Williams-Beuren syndrome

  Codina i Solà, Marta, 1988-; Costa-Roger, Mar; Pérez García, Débora, 1985-; Flores Peirats, Raquel; Palacios Verdú, María Gabriela, 1983-; Cuscó Martí, Ivon, 1973-; Pérez Jurado, Luis Alberto (BMJ Publishing Group, 2019)

  Background: The hallmark of the neurobehavioural phenotype of Williams-Beuren syndrome (WBS) is increased sociability and relatively preserved language skills, often described as opposite to autism spectrum disorders (ASD). ...

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