• Adherence to the mediterranean lifestyle and desired body weight loss in a mediterranean adult population with overweight: a PREDIMED-Plus Study

  Bouzas, Cristina; Zomeño Fajardo, Maria Dolores; Muñoz, Julia; Castañer, Olga; Goday Arno, Alberto; Tur, J. Antoni (MDPI, 2020)

  Background: Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives: The aim of this study was to assess the association between the adherence ...
• Association between the potential influence of a lifestyle intervention in older individuals with excess weight and metabolic syndrome on untreated household cohabitants and their family support: the PREDIMED-Plus Study

  Basora, Josep; Villalobos, Felipe; Pallejà-Millán, Meritxell; Babio, Nancy; Goday Arno, Alberto; Castañer, Olga; Fitó Colomer, Montserrat; Zomeño Fajardo, Maria Dolores; Pintó Sala, Xavier; Sacanella, Emilio; Paz-Graniel, Indira; Salas Salvadó, Jordi (MDPI, 2020)

  This cross-sectional study aims to evaluate the association between the PREDIMED-Plus study lifestyle intervention and (i) adherence to the Mediterranean diet (MedDiet) and (ii) physical activity of cohabiting study ...
• Satellite cells and markers of muscle regeneration during unloading and reloading: effects of treatment with resveratrol and curcumin

  Mañas-García, Laura; Guitart, Maria; Duran Jordà, Xavier, 1974-; Barreiro Portela, Esther (MDPI, 2020)

  We hypothesized that treatment with pharmacological agents known to increase sirtuin-1 activity (resveratrol and curcumin) may enhance muscle regeneration. In limb muscles of mice (C57BL/6J, 10 weeks) exposed to reloading ...
• Down syndrome is a metabolic disease: altered insulin signaling mediates peripheral and brain dysfunctions

  Dierssen, Mara; Fructuoso, Marta; Martínez de Lagrán Cabredo, María; Perluigi, Marzia; Barone, Eugenio (Frontiers, 2020)

  Down syndrome (DS) is the most frequent chromosomal abnormality that causes intellectual disability, resulting from the presence of an extra complete or segment of chromosome 21 (HSA21). In addition, trisomy of HSA21 ...
• Transcriptomic differences in MSA clinical variants

  Pérez Soriano, Alexandra; Arnal, Magdalena; Botta Orfila, Teresa; Giraldo, Darly; Fernández, Manel; Compta, Yaroslau; Fernández-Santiago, Ruben; Ezquerra, Mario; Tartaglia, Gian Gaetano; Martí, M. Josep; Catalan multiple system atrophy-registry (CMSAR) (Nature Research, 2020)

  Background: Multiple system atrophy (MSA) is a rare oligodendroglial synucleinopathy of unknown etiopathogenesis including two major clinical variants with predominant parkinsonism (MSA-P) or cerebellar dysfunction (MSA-C). ...
• COVID-19 y la neumología del siglo XXI: ¿reto u oportunicad?

  Barreiro Portela, Esther; Jiménez, Carlos; García de Pedro, Julia; Ramírez Prieto, María Teresa (Elsevier, 2020)
• Correction: use of health apps by nurses for professional purposes: web-based survey study

  Mayer, Miguel Ángel, 1960- (JMIR Publications Inc., 2019)
• Improved diagnosis of rare disease patients through systematic detection of runs of homozygosity

  Matalonga, Leslie; Laurie, Steven; Papakonstantinou, Anastasios; Piscia, Davide; Mereu, Elisabetta; Bullich, Gemma; Thompson, Rachel; Horvath, Rita; Pérez Jurado, Luis Alberto; Riess, Olaf; Gut, Ivo; van Ommen, Gert-Jan; Lochmüller, Hanns; Beltran, Sergi; RD–Connect Genome-Phenome Analysis Platform and URD-Cat Data Contributors (Elsevier, 2020)

  Autozygosity is associated with an increased risk of genetic rare disease, thus being a relevant factor for clinical genetic studies. More than 2400 exome sequencing data sets were analyzed and screened for autozygosity ...
• Bioavailability of epigallocatechin gallate administered with different nutritional strategies in healthy volunteers

  Andreu-Fernández, Vicente; Almeida Toledano, Laur; Pizarro Lozano, Mª Nieves; Navarro-Tapia, Elisabet; Gómez-Roig, María Dolores; Torre Fornell, Rafael de la; García-Algar, Oscar (MDPI, 2020)

  The flavanol epigallocatechin gallate (EGCG) is being tested for the treatment of several diseases in humans. However, its bioavailability and pharmacokinetic profile needs a better understanding to enable its use in ...
• Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

  Milà Alomà, Marta; Salvadó, Gemma; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; Grau-Rivera, Oriol; Sala Vila, Aleix; Sánchez Benavides, Gonzalo; Arenaza Urquijo, Eider M.; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Molinuevo, José Luis; ALFA Study (Wiley, 2020)

  Introduction: The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. Methods: We used NeuroToolKit and Elecsys® immunoassays to measure cerebrospinal fluid (CSF) ...
• ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)

  Bousquet, Jean; Antó i Boqué, Josep Maria; Agache, Ioana (Wiley, 2020)
• Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: the ENIGMA adventure

  Hoogman, Martine; Vilarroya, Óscar; Franke, Barbara (Wiley, 2020)

  Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main ...
• Epigenomic assessment of cardiovascular disease risk and interactions with traditional risk metrics

  Westerman, Kenneth; Fernández Sanlés, Alba; Patil, Prasad; Sebastiani, Paola; Jacques, Paul; Starr, John M.; Deary ,Ian J.; Liu, Qing; Liu, Simi; Elosua Llanos, Roberto; DeMeo, Dawn L; Ordovás, José M. (Wiley-Blackwell, 2020)

  Background Epigenome-wide association studies for cardiometabolic risk factors have discovered multiple loci associated with incident cardiovascular disease (CVD). However, few studies have sought to directly optimize a ...
• Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

  Zeitlinger, Markus; Koch, Birgit C.P.; Bruggemann, Roger; De Cock, Pieter; Felton, Timothy; Hites, Maya; El, Jennifer; Luque Pardos, Sònia; MacGowan, Alasdair P.; Marriott, Deborah J. E.; Muller, Anouk E.; Nadrah, Kristina; Paterson, David L.; Standing, Joseph F.; Telles, João P.; Wölfl-Duchek, Michael; Thy, Michael; Roberts, Jason A.; PK/PD of Anti-Infectives Study Group (EPASG) of the European Society of Clinical Microbiology, Infectious Diseases (ESCMID) (SpringerOpen, 2020)

  There is an urgent need to identify optimal antiviral therapies for COVID-19 caused by SARS-CoV-2. We have conducted a rapid and comprehensive review of relevant pharmacological evidence, focusing on (1) the pharmacokinetics ...
• NeuroHeal reduces muscle atrophy and modulates associated autophagy

  Marmolejo-Martínez-Artesero, Sara; Romeo-Guitart, David; Mañas-García, Laura; Barreiro Portela, Esther; Casas, Caty (MDPI, 2020)

  Muscle wasting is an unmet medical need which leads to a reduction of myofiber diameter and a negative impact on the functional performance of daily activities. We previously found that a new neuroprotective drug called ...
• Hospital-at-home as an alternative to release the overload of healthcare systems during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic

  Arias-de la Torre, Jorge; Alonso Caballero, Jordi; Martín, Vicente; Valderas Martínez, José María (Elsevier, 2020)
• Do birthrates contribute to sickness absence differences in women? A cohort study in Catalonia, Spain, 2012-2014

  March, Andrew N.; Villar Vinuesa, Rocío, 1976-; Ubalde López, Mònica, 1972-; Benavides, Fernando G. (Fernando García); Serra Saurina, Laura (Public Library of Science (PLoS), 2020)

  Aims: This study explores the differences in sickness absence trends in women according to reproductive age group and medical diagnoses. Methods: Data were obtained from two administrative registries: the Continuous Working ...
• Sickness absence trajectories following labour market participation patterns: a cohort study in Catalonia (Spain), 2012–2014

  Hernando-Rodriguez, Julio C.; Serra Saurina, Laura; Benavides, Fernando G. (Fernando García); Ubalde López, Mònica, 1972- (BioMed Central, 2020)

  Background: Previous studies have focused on the relationship between employment pathways and health-related outcomes based on cross-sectional or longitudinal approaches. However, little is known about the cumulative effects ...
• Circular DNA intermediates in the generation of large human segmental duplications

  Chicote, Javier U.; López Sánchez, Marcos, 1986-; Marquès i Bonet, Tomàs, 1975-; Callizo, José; Pérez Jurado, Luis Alberto; García-España, Antonio (BioMed Central, 2020)

  Background: Duplications of large genomic segments provide genetic diversity in genome evolution. Despite their importance, how these duplications are generated remains uncertain, particularly for distant duplicated genomic ...
• COVID-19: The disease of the Anthropocene

  O'Callaghan Gordo, Cristina; Antó i Boqué, Josep Maria (Elsevier, 2020)

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