• Diffusion-weighted imaging, MR angiography, and baseline data in a systematic multicenter analysis of 3,301 MRI scans of ischemic stroke patients-neuroradiological review within the MRI-GENIE Study

  Drake, Mattias; Giralt-Steinhauer, Eva; Roquer, Jaume; Jiménez Conde, Jordi; Wassélius, Johan (Frontiers, 2020)

  Background: Magnetic resonance imaging (MRI) serves as a cornerstone in defining stroke phenotype and etiological subtype through examination of ischemic stroke lesion appearance and is therefore an essential tool in linking ...
• Early detection of skeletal muscle bioenergetic deficit by magnetic resonance spectroscopy in cigarette smoke-exposed mice

  Pérez-Rial, Sandra; Barreiro Portela, Esther; Fernández Aceñero, María Jesús; Fernández-Valle, María Encarnación; González-Mangado, Nicolás; Peces-Barba, Germán (Public Library of Science (PLoS), 2020)

  Skeletal muscle dysfunction is a common complication and an important prognostic factor in patients with chronic obstructive pulmonary disease (COPD). It is associated with intrinsic muscular abnormalities of the lower ...
• Validation of the spanish version of the questionnaire on patient empowerment in long-term conditions

  Garcimartín Cerezo, Paloma; Comín Colet, Josep; Pardo-Cladellas, Yolanda; Badosa Marcé, Neus; Linas Alonso, Ana Maria; Rosenfeld, Laia; Faraudo, Mercedes; Valero, Oliver; Hidalgo, Encarnacion; Cainzos-Achirica, Miguel; Ruiz, Sonia; Delgado-Hito, Pilar (Public Library of Science (PLoS), 2020)

  Background: Patient empowerment is a key factor in improving health outcomes. Objective: To evaluate the psychometric properties of the Spanish version of the questionnaire on Patient Empowerment in Long-Term Conditions ...
• Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel

  Segura Tigell, Sonia; Gadea, Alejandra; Nonell Mazelón, Lara; Andrades, Evelyn; Sánchez, Silvia; Pujol Vallverdú, Ramon Maria; Hernández Muñoz, Inmaculada; Toll Abelló, Agustín (Public Library of Science (PLoS), 2020)

  Actinic keratosis is a common skin disease that may progress to invasive squamous cell carcinoma if left untreated. Ingenol mebutate has demonstrated efficacy in field treatment of actinic keratosis. However, molecular ...
• "It made me more confident that I have it under control": patient and provider perspectives on moving to a two-drug ART regimen in the United States and Spain

  Davis, Wendy; Mantsios, Andrea; Karver, Tahilin; Murray, Miranda; Punekar, Yogesh; Ward, Douglas; Bredeek, U. Fritz; Moreno, Santiago; Merino, Dolores; Knobel Freud, Hernando; Campis, Antonio; Kerrigan, Deanna (Public Library of Science (PLoS), 2020)

  Background: Two-drug regimens (2DR) to treat HIV infection have the potential to reduce long-term toxicity and increase therapeutic options for people living with HIV (PLHIV). Prior phase III trials, SWORD-1 and SWORD-2, ...
• Skin sensitization in silico protocol

  Johnson, Candice; Mestres i López, Jordi; Myatt,Glenn J. (Elsevier, 2020)

  The assessment of skin sensitization has evolved over the past few years to include in vitro assessments of key events along the adverse outcome pathway and opportunistically capitalize on the strengths of in silico methods ...
• Corrigendum: a multicenter phase II RCT to compare the effectiveness of EMDR versus TAU in patients with a first-episode psychosis and psychological trauma: a protocol design

  Valiente Gómez, Alicia; Pujol, Nuria; Moreno Alcázar, Ana; Radua, Joaquim; Monteagudo-Gimeno, Eila; Gardoki-Souto, Itxaso; Hogg, Bridget; Álvarez, Maria José; Safont, Gemma; Lupo, Walter; Pérez Solá, Victor; Amann, Benedikt Lorenz; FEP-EMDR Research Group (Frontiers, 2020)
• Clinical features associated with strongyloidiasis in migrants and the potential impact of immunosuppression: a case control study

  Martínez-Pérez, Angela; Soriano-Pérez, Manuel Jesús; Salvador, Fernando; Gomez-Junyent, Joan; Villar García, Judit; Santín, Miguel; Muñoz, Carme; González-Cordón, Ana; Salas-Coronas, Joaquín; Sulleiro, Elena; Somoza, Dolors; Treviño, Begoña; Pecorelli, Rosángela; Llaberia-Marcual, Jaume; Lozano-Serrano, Ana Belén; Quinto, Llorenç; Muñoz, José; Requena-Méndez, Ana; Strong-Semtsi Working Group (MDPI, 2020)

  Strongyloides stercoralis is a widely distributed nematode more frequent in tropical areas and particularly severe in immunosuppressed patients. The aim of this study was to determine factors associated with strongyloidiasis ...
• Prevalence and prognostic impact of subclinical pulmonary congestion at discharge in patients with acute heart failure

  Rivas-Lasarte, Mercedes; Maestro, Alba; Fernández-Martínez, Juan; López-López, Laura; Solé-González, Eduard; Vives-Borras, Miquel; Vives-Borras, Miquel; Montero, Santiago; Mesado, Nuria; Pirla, María J.; Mirabet, Sonia; Fluvià, Paula; Brossa, Vicens; Sionis, Alessandro; Roig, Eulàlia; Cinca, Juan; Álvarez-García, Jesus (Wiley, 2020)

  Aims: Residual pulmonary congestion at hospital discharge can worsen the outcomes in patients with heart failure (HF) and can be detected by lung ultrasound (LUS). The aim of this study was to analyse the prevalence of ...
• Severe autoinflammatory manifestations and antibody deficiency due to novel hypermorphic PLCG2 mutations Martín-Nalda, Andrea; Casals López, Ferran; Gimeno, Ramon; Pujol Vallverdú, Ramon Maria; Aróstegui, Juan Ignacio

  Martín-Nalda, Andrea; Casals López, Ferran; Gimeno, Ramon; Pujol Vallverdú, Ramon Maria; Aróstegui, Juan Ignacio (SpringerOpen, 2020)

  Autoinflammatory diseases (AIDs) were first described as clinical disorders characterized by recurrent episodes of seemingly unprovoked sterile inflammation. In the past few years, the identification of novel AIDs expanded ...
• Altered subcortical emotional salience processing differentiates parkinson's patients with and without psychotic symptoms

  Knolle, Franziska; Garofalo, S.; Viviani, R.; Justicia Díaz, Azucena; Ermakova, Anna O.; Blank, H.; Williams, G.B.; Arrondo, G.; Ramachandra, P.; Tudor-Sfetea, C.; Tudor-Sfetea, C.; Bunzeck, Nico; Düzel, Emrah; Robbins, T.W.; Barker, R.A.; Murray, Graham K. (Elsevier, 2020)

  Objective: Current research does not provide a clear explanation for why some patients with Parkinson's Disease (PD) develop psychotic symptoms. The 'aberrant salience hypothesis' of psychosis has been influential and ...
• Psychiatry in the aftermath of COVID-19

  Vieta, Eduard; Pérez Solá, Victor; Arango, Celso (Elsevier, 2020)
• Articular angioedema in patients with chronic spontaneous urticaria is frequently misdiagnosed as arthritis

  Toubi, Elias; Giménez Arnau, Anna Maria; Maurer, Marcus; Vadasz, Zahava (Elsevier, 2020)
• Influence of age on the occurrence of adverse events in rheumatic patients at the onset of biological treatment: data from the BIOBADASER III registrer

  Vela, Paloma; Sánchez-Piedra, Carlos; Pérez-García, Carolina; Castro-Villegas, María C.; Freire, Mercedes; Mateo, Lourdes; Díaz-Torné, Cesar; Bohórquez, Cristina; Blanco-Madrigal, Juan M.; Ros-Vilamajo, Inmaculada; Gómez, Silvia; Caño, Rocio; Sánchez-Alonso, Fernando; Díaz-González, Federico; Gómez-Reino, Juan J. (BioMed Central, 2020)

  Objectives: To assess whether age, at the beginning of biologic treatment, is associated with the time a first adverse event (AE) appears in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), or psoriatic ...
• Mediterranean diet Effects on type 2 diabetes prevention, disease progression, and related mechanisms. A review

  Martín-Peláez, Sandra; Fitó Colomer, Montserrat; Castañer, Olga (MDPI, 2020)

  The search for a quality diet has grown over the past decade. Diet is considered one of the pillars for the prevention and progression of several diseases, among them: diabetes. Type 2 diabetes (T2D) is an epidemic of ...
• Adherence to the mediterranean lifestyle and desired body weight loss in a mediterranean adult population with overweight: a PREDIMED-Plus Study

  Bouzas, Cristina; Zomeño Fajardo, Maria Dolores; Muñoz, Julia; Castañer, Olga; Goday Arno, Alberto; Tur, J. Antoni (MDPI, 2020)

  Background: Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives: The aim of this study was to assess the association between the adherence ...
• Association between the potential influence of a lifestyle intervention in older individuals with excess weight and metabolic syndrome on untreated household cohabitants and their family support: the PREDIMED-Plus Study

  Basora, Josep; Villalobos, Felipe; Pallejà-Millán, Meritxell; Babio, Nancy; Goday Arno, Alberto; Castañer, Olga; Fitó Colomer, Montserrat; Zomeño Fajardo, Maria Dolores; Pintó Sala, Xavier; Sacanella, Emilio; Paz-Graniel, Indira; Salas Salvadó, Jordi (MDPI, 2020)

  This cross-sectional study aims to evaluate the association between the PREDIMED-Plus study lifestyle intervention and (i) adherence to the Mediterranean diet (MedDiet) and (ii) physical activity of cohabiting study ...
• Satellite cells and markers of muscle regeneration during unloading and reloading: effects of treatment with resveratrol and curcumin

  Mañas-García, Laura; Guitart, Maria; Duran Jordà, Xavier, 1974-; Barreiro Portela, Esther (MDPI, 2020)

  We hypothesized that treatment with pharmacological agents known to increase sirtuin-1 activity (resveratrol and curcumin) may enhance muscle regeneration. In limb muscles of mice (C57BL/6J, 10 weeks) exposed to reloading ...
• Down syndrome is a metabolic disease: altered insulin signaling mediates peripheral and brain dysfunctions

  Dierssen, Mara; Fructuoso, Marta; Martínez de Lagrán Cabredo, María; Perluigi, Marzia; Barone, Eugenio (Frontiers, 2020)

  Down syndrome (DS) is the most frequent chromosomal abnormality that causes intellectual disability, resulting from the presence of an extra complete or segment of chromosome 21 (HSA21). In addition, trisomy of HSA21 ...
• Transcriptomic differences in MSA clinical variants

  Pérez Soriano, Alexandra; Arnal, Magdalena; Botta Orfila, Teresa; Giraldo, Darly; Fernández, Manel; Compta, Yaroslau; Fernández-Santiago, Ruben; Ezquerra, Mario; Tartaglia, Gian Gaetano; Martí, M. Josep; Catalan multiple system atrophy-registry (CMSAR) (Nature Research, 2020)

  Background: Multiple system atrophy (MSA) is a rare oligodendroglial synucleinopathy of unknown etiopathogenesis including two major clinical variants with predominant parkinsonism (MSA-P) or cerebellar dysfunction (MSA-C). ...

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