• Type 2 diabetes mellitus and cancer: epidemiology, physiopathology and prevention

  Rey-Reñones, Cristina; Baena Díez, Jose M.; Aguilar-Palacio, Isabel; Miquel, Cristina; Grau Magaña, Maria (MDPI, 2021)

  Individuals with type 2 diabetes mellitus are at greater risk of developing cancer and of dying from it. Both diseases are age-related, contributing to the impact of population aging on the long-term sustainability of ...
• The 3-year effect of the mediterranean diet intervention on inflammatory biomarkers related to cardiovascular disease

  Urpi-Sardà, Mireia; Casas, Rosa; Sacanella, Emilio; Corella, Dolores; Andrés-Lacueva, Cristina; Llorach, Rafael; Garrabou, Glòria; Cardellach, Francesc; Sala Vila, Aleix; Ros, Emilio; Ruiz-Canela, Miguel; Fitó Colomer, Montserrat; Salas-Salvadó, Jordi; Estruch, Ramón (MDPI, 2021)

  The intervention with the Mediterranean diet (MD) pattern has evidenced short-term anti-inflammatory effects, but little is known about its long-term anti-inflammatory properties at molecular level. This study aims to ...
• Systemic profiles of microRNAs, redox balance, and inflammation in lung

  Qin, Liyun; Guitart, Maria; Curull Serrano, Víctor; Sánchez-Font, Albert; Duran, Xavier; Tang, Jun; Admetlló Papiol, Mireia; Barreiro Portela, Esther (MDPI, 2021)

  Lung cancer (LC) risk increases in patients with chronic respiratory diseases (COPD). MicroRNAs and redox imbalance are involved in lung tumorigenesis in COPD patients. Whether systemic alterations of those events may also ...
• NF-κB-dependent and -independent (moonlighting) IκBα functions in differentiation and cancer

  Espinosa Blay, Lluís (MDPI, 2021)

  IκBα is considered to play an almost exclusive role as inhibitor of the NF-κB signaling pathway. However, previous results have demonstrated that SUMOylation imposes a distinct subcellular distribution, regulation, ...
• Iron replacement and redox balance in non-anemic and mildly anemic iron deficiency COPD patients: insights from a clinical trial

  Pérez-Peiró, Maria; Martín-Ontiyuelo, Clara; Rodó-Pin, Anna; Piccari, Lucilla; Admetlló Papiol, Mireia; Duran Jordà, Xavier, 1974-; Rodríguez Chiaradia, Diego Agustín; Barreiro Portela, Esther (MDPI, 2021)

  In COPD patients, non-anemic iron deficiency (NAID) is a common systemic manifestation. We hypothesized that in COPD patients with NAID, iron therapy may improve systemic oxidative stress. The FACE (Ferinject assessment ...
• Familial hypercholesterolemia: do HDL play a role

  Pedro-Botet, Juan Carlos; Climent Biescas, Elisenda; Benaiges Foix, David (MDPI, 2021)

  Cardiovascular disease (CVD) in heterozygous familial hypercholesterolemia (HeFH), the most frequent monogenic disorder of human metabolism, is largely driven by low-density lipoprotein (LDL) cholesterol concentrations. ...
• Differences in nutritional status and inflammatory biomarkers between female and male patients with bronchiectasis: a large-cohort study

  Wang, Xuejie; Villa, Carmen; Dobarganes, Yadira; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-García, Miguel Ángel; Rodriguez, Juan Luis; Rosa, David de la; Duran, Xavier; Barreiro Portela, Esther (MDPI, 2021)

  We hypothesized that systemic inflammatory and nutritional parameters may differ between male and female patients with non-CF bronchiectasis. In a large patient cohort from the Spanish Online Bronchiectasis Registry (RIBRON), ...
• Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study

  Wang, Gang; Casas Sanahuja, Maribel; Abellan, Alicia; García Aymerich, Judith; Sunyer Deu, Jordi; Melén, Erik (UNLISTED PUBLISHER, 2021)

  Background: The prevalences of obstructive and restrictive spirometric phenotypes, and their relation to early-life risk factors from childhood to young adulthood remain poorly understood. The aim was to explore these ...
• Soundtrack of life: an fMRI study

  Falcon, Carles; Navarro-Plaza, Mari Carmen; Gramunt Fombuena, Nina; Arenaza Urquijo, Eider M.; Grau-Rivera, Oriol; Cacciaglia, Raffaele; González de Echávarri, José Maria; Sanchez-Benavides, Gonzalo; Operto, Grégory; Knezevic, Iva; Molinuevo, José Luis; Domingo Gispert, Juan (Elsevier, 2022)

  Most people have a soundtrack of life, a set of special musical pieces closely linked to certain biographical experiences. Autobiographical memories (AM) and music listening (ML) involve complex mental processes ruled by ...
• Implementation of clinical practices and pathways optimizing ACS patients lipid management: focus on eight European initiatives

  Alings, Marco; Descamps, Olivier; Guillon, Benoit; Leosdottir, Margret; Maggioni, Aldo P.; Recasens, Lluís; Speidl, Walter S.; Tripodi, Rosario V.; Landmesser, Ulf; Catapano, Alberico L.; Pirillo, Angela (Elsevier, 2020)

  Post-acute coronary syndrome (ACS) patients are at very high cardiovascular risk. Despite current guidelines strongly recommend to reduce LDL-C levels and initiation of high-intensity statins as early as possible in patients ...
• Spontaneous pneumothorax in COVID-19 patients

  Marsico, Salvatore; Del Carpio Bellido, Luis Alexandre; Zuccarino, Flavio (Elsevier, 2021)
• Spontaneous pneumomediastinum and macklin effect in COVID-19 patients

  Marsico, Salvatore; Del Carpio Bellido, Luis Alexandre; Zuccarino, Flavio (Elsevier, 2021)
• Nonparticipation selection bias in the MOBI-Kids Study

  Turner, Michelle C.; Gracia-Lavedan, Esther; Langer, Chelsea Eastman; Castaño Vinyals, Gemma; Albert, Alex; Badia, Francesc; Carretero, Gema; Cardis, Elisabeth (Lippincott Williams & Wilkins, 2019)

  Background: MOBI-Kids is a 14-country case-control study designed to investigate the potential effects of electromagnetic field exposure from mobile telecommunications devices on brain tumor risk in children and young ...
• SPOP and CHD1 alterations in prostate cancer: Relationship with PTEN loss, tumor grade, perineural infiltration, and PSA recurrence

  Hernández Llodrà, Sílvia; Segalés Tañà, Laura, 1994-; Juanpere, Nuria; Lorenzo, Marta; Salido Galeote, Marta; Nonell Mazelón, Lara; López, David; Rodríguez-Vida, Alejo; Bellmunt Molins, Joaquim, 1959-; Fumadó Ciutat, Lluis; Cecchini Rosell, Lluís; Lloreta Trull, Josep, 1958- (Wiley, 2021)

  Background: In the non-ETS fusion of prostate cancer (PCa) pathway, SPOP mutations emerge as a distinct oncogenic driver subclass. Both SPOP downregulation and mutation can lead to SPOP target stabilization promoting ...
• Health and environmental impacts of drinking water choices in Barcelona, Spain: A modelling study

  Villanueva, Cristina M.; Garfí, Marianna; Milà, Carles; Olmos, Sergio; Ferrer, Ivet; Tonne, Cathryn (Elsevier, 2021)

  Quantitative evidence of health and environmental tradeoffs between individuals' drinking water choices is needed to inform decision-making. We evaluated health and environmental impacts of drinking water choices using ...
• The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment

  Callegaro, Giulia; Kunnen, Steven J.; Trairatphisan, Panuwat; Grosdidier, Solène; Niemeijer, Marije; den Hollander, Wouter; Guney, Emre; Piñero González, Janet, 1977-; Furlong, Laura I.; Webster, Yue W.; Saez-Rodriguez, Julio; Sutherland, Jeffrey J.; Mollon, Jennifer; Stevens, James L.; van de Water, Bob (SpringerOpen, 2021)

  Mechanism-based risk assessment is urged to advance and fully permeate into current safety assessment practices, possibly at early phases of drug safety testing. Toxicogenomics is a promising source of mechanisms-revealing ...
• Modulation of telomere length by mediterranean diet, caloric restriction, and exercise: results from PREDIMED-Plus Study

  Fernández de la Puente, María; Hernández-Alonso, Pablo; Canudas i Puig, Sílvia; Martí, Amelia; Fitó Colomer, Montserrat; Razquin, Cristina; Salas Salvadó, Jordi (MDPI, 2021)

  Telomere length (TL) has been associated with aging and is determined by lifestyle. However, the mechanisms by which a dietary pattern such as the Mediterranean diet (MedDiet) affects TL homeostasis are still unknown. Our ...
• Antioxidants threaten multikinase inhibitor efficacy against liver cancer by blocking mitochondrial reactive oxygen species

  Cucarull-Martínez, Blanca; Tutusaus, Anna; Hernáez-Alsina, Tania; García de Frutos, Pablo; Reig, María; Colell, Anna; Marí, Montserrat; Morales, Albert (MDPI, 2021)

  Sorafenib and regorafenib, multikinase inhibitors (MKIs) used as standard chemotherapeutic agents for hepatocellular carcinoma (HCC), generate reactive oxygen species (ROS) during cancer treatment. Antioxidant supplements ...
• Prenatal exposure to fluoride and neuropsychological development in early childhood: 1-to 4 years old children

  Ibarluzea, Jesús; Gallastegi, Mara; Santa Marina, Loreto; Jiménez-Zabala, Ana; Arranz, Enrique; Molinuevo, Amaia; Lopez-Espinosa, Maria-José; Ballester Díez, Ferran; Villanueva, Cristina M.; Riano-Galan, Isolina; Sunyer Deu, Jordi; Tardón, Adonina; Lertxundi, Aitana (Elsevier, 2022)

  Background: Cross-sectional and prospective studies have provided evidence of the neurotoxic effect of early exposure to fluoride (F) in pregnancy. It has been negatively associated with cognitive development during ...
• Influence of gestational weight gain on the organochlorine pollution content of breast milk

  Grimalt Obrador, Joan; Garí de Barbarà, Mercè, 1982-; Santa Marina, Loreto; Ibarluzea, Jesús; Sunyer Deu, Jordi (Elsevier, 2022)

  Background: Transplacental transfer and breastfeeding are the main transport routes of organic pollutants into children at the beginning of life. Although pollutant transmission through these mechanisms primarily depends ...

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