• Comparison of autofluorescence and white-light bronchoscopies performed with the Evis Lucera Spectrum for the detection of bronchial cancers: a meta-analysis

  Sun, Shuangshuang; Yang, Yang; Chen, Meizi; Wang, Li; Pan, Hangcheng; Zhang, Xiuwei; Wagnieres, Georges; Mohammad, Yousser; Barreiro Portela, Esther; Pirozzolo, Giovanni; Villeneuve, P. James; Zhan, Ping; Wan, Bing; AME Lung Cancer Collaborative Group (Pioneer Bioscience Publishing Company, 2020)

  Background: Many recent studies have reported that autofluorescence bronchoscopy (AFB) has a superior sensitivity and decreased specificity in the diagnosis of bronchial cancers when compared with white-light bronchoscopy ...
• Thromboembolic, cardiovascular and overall mortality risks of aromatase inhibitors, compared with tamoxifen treatment: an outpatient-register-based retrospective cohort study

  Pineda-Moncusí, Marta; Garcia Giralt, Natàlia; Díez Pérez, Adolfo; Tusquets Trias de Bes, Ignacio; Servitja Tormo, Sonia; Albanell Mestres, Joan; Prieto-Alhambra, Daniel; Nogués Solan, Francesc Xavier (SAGE Publications, 2020)

  Background: Tamoxifen (TAM) and aromatase inhibitor (AI) therapies have been associated with increased risk of thromboembolic and cardiovascular events, respectively, in addition to other side effects. This study analysed ...
• Gestational diabetes impacts fetal precursor cell responses with potential consequences for offspring

  Algaba-Chueca, Francisco; Maymó-Masip, M.Elsa; Ejarque, Miriam; Ballesteros, Mónica; Llauradó Cabot, Gemma; López, Carlos; Guarque, Albert; Serena, Carolina; Martínez-Guasch, Laia; Gutiérrez, Cristina; Bosch, Ramón; Vendrell, Joan; Megia, Ana; Fernández Veledo, Sonia (Wiley, 2020)

  Fetal programming has been proposed as a key mechanism underlying the association between intrauterine exposure to maternal diabetes and negative health outcomes in offspring. To determine whether gestational diabetes ...
• MMP-10 is increased in early stage diabetic kidney disease and can be reduced by renin-angiotensin system blockade

  Mora-Gutiérrez, José María; Rodríguez, José Antonio; Fernández-Seara, María A.; Orbe, Josune; Escalada, Francisco Javier; Soler, María José; Slon Roblero, María Fernanda; Riera Oliva, Marta; Páramo, José Antonio; García-Fernández, Nuria (Nature Research, 2020)

  Matrix metalloproteinases have been implicated in diabetic microvascular complications. However, little is known about the pathophysiological links between MMP-10 and the renin-angiotensin system (RAS) in diabetic kidney ...
• Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study

  Rojo-Martínez, Gemma; Goday Arno, Alberto; Calle-Pascual, Alfonso (Nature Research, 2020)

  Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population. In total 5072 people older than 18 years,were ...
• Creating urban green infrastructure where it is needed - A spatial ecosystem service-based decision analysis of green roofs in Barcelona

  Langemeyer, Johannes; Wedgwood, Diego; McPhearson, Timon; Baró Porras, Francesc; Madsen, Anders L.; Barton, David N. (Elsevier, 2020)

  As cities face increasing pressure from densification trends, green roofs represent a valuable source of ecosystem services for residents of compact metropolises where available green space is scarce. However, to date ...
• Reduced airway levels of fatty-acid binding protein 4 in COPD: relationship with airway infection and disease severity

  Perea, Lídia; Rodrigo-Troyano, Ana; Cantó, Elisabet; Domínguez-Álvarez, Marisol; Giner, Jordi; Sanchez-Reus, Ferran; Villar García, Judit; Quero, Sara; García-Nuñez, Marian; Marín, Alicia; Monsó, Eduard; Faner, Rosa; García-Nuñez, Marian; Vidal, Silvia; Sibila, Oriol (BioMed Central, 2020)

  Background: For still unclear reasons, chronic airway infection often occurs in patients with Chronic Obstructive Pulmonary Disease (COPD), particularly in those with more severe airflow limitation. Fatty-acid binding ...
• Becoming a mother entails anatomical changes in the ventral striatum of the human brain that facilitate its responsiveness to offspring cues

  Hoekzema, Elseline; Tamnes, Christian K.; Berns, Puck; Barba-Müller, Erika; Pozzobon, Cristina; Picado, Marisol; Lucco, Florencio; Martínez-García, Magdalena; Desco, Manuel; Ballesteros, Agustín; Crone, Eveline A.; Vilarroya, Óscar; Carmona, Susanna (Elsevier, 2020)

  In mothers, offspring cues are associated with a powerful reinforcing value that motivates maternal care. Animal studies show that this is mediated by dopamine release into the nucleus accumbens, a core component of the ...
• Psychoeducation for bipolar disorder and risk of recurrence and hospitalization - a within-individual analysis using registry data

  Joas, Erik; Bäckman, Kristoffer; Karanti, Alina; Sparding, Timea; Colom, Francesc; Pålsson, Erik; Landén, Mikael (Cambridge University Press, 2020)

  Background: The efficacy of psychoeducation for bipolar disorder has been demonstrated in clinical trials, but it is not known if the results translate into effectiveness in routine clinical practice. The aim was to determine ...
• Surface respiratory electromyography and dyspnea in acute heart failure patients

  Luiso, Daniele; Villanueva, Jair A.; Belarte-Torner, Laia C.; Fort, Aleix; Blázquez-Bermejo, Zorba; Ruiz, Sonia; Farré, Ramon; Rigau, Jordi; Martí Almor, Julio; Farré López, Núria (Public Library of Science (PLoS), 2020)

  Introduction and objectives: Dyspnea is the most common symptom among hospitalized patients with heart failure (HF) but besides dyspnea questionnaires (which reflect the subjective patient sensation and are not fully ...
• ReorientExpress: reference-free orientation of nanopore cDNA reads with deep learning

  Ruiz Reche, Angel; Srivastava, Akanksha; Indi, Joel A.; de la Rubia, Ivan; Eyras Jiménez, Eduardo (BioMed Central, 2019)

  We describe ReorientExpress, a method to perform reference-free orientation of transcriptomic long sequencing reads. ReorientExpress uses deep learning to correctly predict the orientation of the majority of reads, and in ...
• Longitudinal association of changes in diet with changes in body weight and waist circumference in subjects at high cardiovascular risk: the PREDIMED trial

  Konieczna, Jadwiga; Romaguera Bosch, Dora; Pereira, Verónica; Fiol, Miquel; Razquin, Cristina; Estruch, Ramón; Asensio, Eva M.; Babio, Nancy; Fitó Colomer, Montserrat; Gómez Gracia, Enrique; Ros, Emilio; Lapetra, José; Arós, Fernando; Serra Majem, Lluís; Pintó Sala, Xavier; Toledo, Estefania; Sorlí, José V.; Bulló, Mònica; Schröder, Helmut, 1958-; Martínez-González, Miguel A. (BioMed Central, 2019)

  Background: Consumption of certain foods is associated with long-term weight gains and abdominal fat accumulation in healthy, middle-aged and young, non-obese participants. Whether the same foods might be associated with ...
• Hydroxychloroquine and Chloroquine for treatment of SARS-CoV-2 (COVID-19)

  Pastick, Katelyn A.; Okafor, Elizabeth C.; Wang, Fan; Lofgren, Sarah M.; Skipper, Caleb P.; Nicol, Melanie R.; Pullen, Matthew F.; Rajasingham, Radha; McDonald, Emily G.; Lee, Todd C.; Schwartz, Ilan S.; Kelly, Lauren E.; Lother, Sylvain A.; Mitjà, Oriol; Letang Jiménez de Anta, Emilio Ángel; Abassi, Mahsa; Boulware, David R. (Oxford University Press, 2020)

  Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly emerging viral infection causing coronavirus disease 2019 (COVID-19). Hydroxychloroquine and chloroquine have garnered unprecedented attention as ...
• A phase 3 study to compare delafloxacin with moxifloxacin for the treatment of adults with community-acquired bacterial pneumonia (DEFINE-CABP)

  Horcajada Gallego, Juan Pablo; Salata, Robert A.; Álvarez-Sala, Rodolfo; Nitu, Floarea Mimi; Lawrence, Laura; Quintas, Megan; Cheng, Chun-Yen; Cammarata, Sue; DEFINE-CABP Study Group (Oxford University Press, 2020)

  Background: The clinical and economic burden of community-acquired bacterial pneumonia (CABP) is significant and is anticipated to increase as the population ages and pathogens become more resistant. Delafloxacin is a ...
• Associations of sickness absence for pain in the low back, neck and shoulders with wider propensity to pain

  Coggon, David; Serra, Consol; Harcombe, Helen (BMJ Publishing Group, 2020)

  Objectives: To explore the association of sickness absence ascribed to pain at specific anatomical sites with wider propensity to musculoskeletal pain. Methods: As part of the CUPID (Cultural and Psychosocial Influences ...
• The relation of CUN-BAE Index with Body Mass Index and waist circumference in adults aged 50 to 85 Years: the MCC-Spain Study

  Davila-Batista, Veronica; Romaguera Bosch, Dora; Castaño Vinyals, Gemma; Kogevinas, Manolis; Martín Sánchez, Vicente; McC-Spain Study Group (MDPI, 2020)

  Backgound: Traditional anthropometrics such as body mass index (BMI) or waist circumference (WC) do not fully capture the complex biology of body fat (BF) in the elderly. The Clinica Universidad de Navarra-Body Adiposity ...
• Dietary polyphenol intake is associated with HDL-cholesterol and a better profile of other components of the metabolic syndrome: a PREDIMED-Plus sub-study

  Castro-Barquero, Sara; Fitó Colomer, Montserrat; Castañer, Olga; Sanllorente Melenchón, Albert; Estruch, Ramón (MDPI, 2020)

  Dietary polyphenol intake is associated with improvement of metabolic disturbances. The aims of the present study are to describe dietary polyphenol intake in a population with metabolic syndrome (MetS) and to examine the ...
• The dietary inflammatory index and chronic lymphocytic leukaemia in the MCC Spain Study

  Flores, José Carlos; Gracia Lavedan, Esther; Romaguera Bosch, Dora; Gimeno Vázquez, Eva; Kogevinas, Manolis; Castaño Vinyals, Gemma; Casabonne, Delphine (MDPI, 2020)

  Chronic inflammation plays a role in the development of chronic lymphocytic leukaemia (CLL), and diet might modulate chronic inflammation. This study aims to evaluate the association between the dietary inflammatory index ...
• Leisure-Time physical activity, sedentary behaviour and diet quality are associated with metabolic syndrome severity: the PREDIMED-Plus Study

  Gallardo-Alfaro, Laura; Fitó Colomer, Montserrat; Zomeño Fajardo, Maria Dolores; Pérez-Vega, Karla Alejandra; Tur, J. Antoni (MDPI, 2020)

  Healthy lifestyle factors, such as physical activity (PA) and Mediterranean diet (MD), decrease the likelihood of developing metabolic syndrome (MetS). The aim of this study was to report main lifestyle components and ...
• Effects of Virgin Olive oil and phenol-enriched virgin olive oils on lipoprotein atherogenicity

  Farràs Mañé, Marta; Canyelles, Marina; Fitó Colomer, Montserrat; Escolà-Gil, Joan Carles (MDPI, 2020)

  The atherogenicity of low-density lipoprotein (LDL) and triglyceride-rich lipoproteins (TRLs) may be more significant than LDL cholesterol levels. Clinical trials which have led to increased high-density lipoprotein (HDL) ...

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