Welcome to the UPF Digital Repository

Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM))

Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM))

 

Recent Submissions

  • Sanabria Sanchinel, Abel Alejandro; Esteban Floria, María Olivia; Tejero Juste, Carlos; Nuñez Benito, María Esther (Universidad Nacional De Cordoba, Facultad De Ciencias Medicas, 2019)
    El síndrome de isquemia ocular es causado por la hipoperfusión ocular crónica debido a estenosis u oclusión de arteria carótida común o interna ipsilateral. Presentamos el caso de un varón de 58 años con episodios de ...
  • Mensen, Vincent T.; Vreeker, Annabel; Nordgren, Johan; Atkinson, Amanda; Torre Fornell, Rafael de la; Farré Albaladejo, Magí; Ramaekers, Johannes G.; Brunt, Tibor M. (SpringerOpen, 2019)
    Background: Synthetic cannabinoids (SCs) are a class of new psychoactive substances that have been rapidly evolving around the world throughout recent years. Many different synthetic cannabinoid analogues are on the consumer ...
  • Suñol, Maria; Martínez-Zalacaín, Ignacio; Picó-Pérez, Maria; López-Solà, Clara; Real, Eva; Fullana Rivas, Miguel Ángel; Pujol Nuez, Jesús; Cardoner, Narcís; Menchón, José M.; Alonso, Pino; Soriano Mas, Carles (Cambridge University Press, 2020)
    Background: Preliminary evidence suggests that hoarding disorder (HD) and obsessive-compulsive disorder (OCD) may show distinct patterns of brain activation during executive performance, although results have been inconclusive ...
  • Casas, Ana I.; Hassan, Ahmed; Larsen, Simon J.; Gomez-Rangel, Vanessa; Elbatreek, Mahmoud; Kleikers, Pamela W. M.; Guney, Emre; Egea, Javier; López, Manuela G.; Baumbach, Jan; Schmidt, Harald H.H.W. (National Academy of Sciences, 2019)
    Drug discovery faces an efficacy crisis to which ineffective mainly single-target and symptom-based rather than mechanistic approaches have contributed. We here explore a mechanism-based disease definition for network ...
  • Sala Serra, Maria; Pérez-Lacasta, Maria José; Martínez-Alonso, Montserrat; García, Montse; Sala Serra, Maria; Perestelo-Pérez, Lilisbeth; Vidal, Carmen; Codern, Núria; Feijoo-Cid, Maria; Toledo-Chávarri, Ana; Cardona, Àngels; Pons, Anna; Carles, Misericòrdia; Rué, Montserrat; InforMa Group (Public Library of Science (PLoS), 2019)
    Background: In Spain, women invited to breast screening are not usually informed about potential harms of screening. The objective of the InforMa study is to assess the effect of receiving information about the benefits ...
  • Fa-Binefa, Manel; Clarà Velasco, Alberto; Pérez-Fernández, Silvia; Grau Magaña, Maria; Dégano, Irene R.; Martí-Lluch, Ruth; Ramos, Rafel; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto (Elsevier, 2019)
    Early smoking onset age (SOA) is a public health concern with scant empirical evidence of its role in health outcomes. The study had two aims: i) to assess whether an early SOA was associated with the risk of fatal and ...
  • Ordi, Jaume (Public Library of Science (PLoS), 2019)
    Background: Clinico-pathological discrepancies are more frequent in settings in which limited diagnostic techniques are available, but there is little information on their actual impact. Aim: We assessed the accuracy of ...
  • Maseda, Emilio; Ramírez, Sofía; Picatto, Pedro; Peláez-Peláez, Eva; García-Bernedo, Carlos A.; Ojeda-Betancur, Nazario; Aguilar, Gerardo; Forés, Beatriz; Solera-Marín, Jorge; Aliaño-Piña, María; Tamayo Aguirre, Eduardo; Ramasco, Fernando; García-Álvarez, Raquel; González-Lisorge, Ada; Giménez, Maria-José; Suárez-de-la-Rica, Alejandro; HELP Investigators and the Perioperative Infection Research Group (Public Library of Science (PLoS), 2019)
    The concept of healthcare-associated infections (as opposed to hospital-acquired infections) in intraabdominal infections (IAIs) is scarcely supported by data in the literature. The aim of the present study was to analyse ...
  • Gu, Yuchen; Moroy, Gautier; Paul, Jean-Louis; Rebillat, Anne-Sophie; Dierssen, Mara; Torre Fornell, Rafael de la; Cieuta-Walti, Cécile; Dairou, Julien; Janel, Nathalie (MDPI, 2020)
    Epigallocatechin gallate (EGCG) is an inhibitor of DYRK1A, a serine/threonine kinase considered to be a major contributor of cognitive dysfunctions in Down syndrome (DS). Two clinical trials in adult patients with DS have ...
  • Llauradó Cabot, Gemma; Cano, Albert; Albert, Lara; Ballesta, Silvia; Mazarico, Isabel; Luchtenberg, María-Florencia; González Sastre, Montserrat; Megia, Ana; Simó, Rafael; Vendrell, Joan; González Clemente, José (Public Library of Science (PLoS), 2019)
    Objectives: Currently used risk scores for type 2 diabetes mellitus (T2DM) clearly underestimate cardiovascular risk in type 1 diabetes (T1DM). Hence, there is a need to develop novel and specific risk-estimation tools for ...
  • Hernáez, Álvaro; Soria-Florido, Maria; Schröder, Helmut, 1958-; Ros, Emilio; Pinto, Xavier; Estruch, Ramón; Salas-Salvadó, Jordi; Corella, Dolores; Arós, Fernando; Serra-Majem, Luis; Martínez-González, Miguel A.; Fiol, Miquel; Lapetra, José; Elosua Llanos, Roberto; Lamuela-Raventós, Rosa M.; Fitó Colomer, Montserrat (Public Library of Science (PLoS), 2019)
    Background: High-density lipoprotein (HDL) functionality and low-density lipoprotein (LDL) atherogenic traits can describe the role of both particles on cardiovascular diseases more accurately than HDL- or LDL-cholesterol ...
  • Boyce, Alison M.; Casey, Rachel K.; Ovejero Crespo, Diana; Murdock, Cynthia M.; Estrada, Andrea; Guthrie, Lori C.; Brillante, Beth A.; Gomez-Lobo, Veronica; Nieman, Lynette K.; Collins, Michael T. (BioMed Central, 2019)
    Background: Autonomous ovarian activation with recurrent estrogen-producing cysts is a hallmark feature of the rare bone and endocrine disorder fibrous dysplasia/McCune-Albright syndrome. Precocious puberty in girls with ...
  • Ruiz-Arenas, Carlos; Cáceres, Alejandro; López Sánchez, Marcos, 1986-; Tolosana, Ignacio; Pérez Jurado, Luis Alberto; González Ruiz, Juan Ramón (Public Library of Science (PLoS), 2019)
    Polymorphic inversions contribute to adaptation and phenotypic variation. However, large multi-centric association studies of inversions remain challenging. We present scoreInvHap, a method to genotype inversions from SNP ...
  • Ciruelos, Eva; Alba, Emilio; López, Rafael; Lluch, Ana; Martín, Miguel; Arroyo, Isabel; Navarro, Beatriz; Carcedo, David; Colomer, Ramon; Albanell Mestres, Joan (Impact Journals, 2019)
    Introduction: Trastuzumab has become the standard treatment for both HER2-positive early and metastatic breast cancer (HER2+ eBC or mBC) since its approval. The objective of the study is to estimate the benefit of adjuvant ...
  • Buxeda, Anna; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Bartolomé, Álvaro; Mir Fontana, M. Luisa; Pascual-Dapena, Ana; Sans, Anna; Duran Jordà, Xavier, 1974-; Crespo Barrio, Marta; Pascual Santos, Julio (Impact Journals, 2019)
    Kidney transplant (KT) recipients are at greater risk of developing some cancers than the general population. Moreover, cancer is the only cause of death that is currently increasing after kidney transplantation. We analyzed ...
  • Costa, Dolors; Grau, Javier; Espinet Solà, Blanca; Arias, Amparo; Gómez, Cándida; López-Guerra, Mónica; Nomdedeu, Meritxell; Cervantes, Francisco (Spandidos Publications, Ltd., 2019)
    BCR/ABL1 gene fusion is the hallmark of chronic myeloid leukemia (CML), and is generated in 5-10% of patients by a variant translocation involving 9q34, 22q11.2 and one or more additional genomic regions. The objective of ...
  • Cebrià i Costa, Joan Pau, 1989-; Pascual-Reguant, Laura; Gonzalez-Perez, Abel; Serra-Bardenys, Gemma; Querol, J.; Cosín, M.; Verde, Gaetano; Cigliano, R. A.; Sanseverino, Walter; Segura-Bayona, Sandra; Iturbide Martínez de Albéniz, Ane, 1989-; Andreu Martínez, David; Nuciforo, Paolo G.; Bernado-Morales, C.; Rodilla, Verónica; Arribas, Joaquín; Yelamos López, Jose; García de Herreros, Antonio; Stracker, Travis; Peiró Sales, Sandra (Nature Research, 2020)
    Oxidation of H3 at lysine 4 (H3K4ox) by lysyl oxidase-like 2 (LOXL2) generates an H3 modification with an unknown physiological function. We find that LOXL2 and H3K4ox are higher in triple-negative breast cancer (TNBC) ...
  • Oliveras, Anna; Goday Arno, Alberto; Sans Atxer, Laia; Vázquez, Susana; Benaiges Foix, David; Ramón Moros, José Manuel; Pascual Santos, Julio (Springer, 2020)
    Background: Weight loss is associated to blood pressure (BP) reduction in obese patients. There is no information on central 24-h BP changes after bariatric surgery (BS). Methods and results: In this study, we analyzed ...
  • Hardy-Werbin, Max; Rocha, Pedro P.; Arpí Llucià, Oriol; Taus García, Álvaro; Nonell Mazelón, Lara; Duran Jordà, Xavier, 1974-; Villanueva, Xavier; Joseph-Pietras, Deborah; Nolan, Luke; Danson, Sarah; Griffiths, Richard; López-Botet, M. (Miguel); Rovira Guerín, Ana; Albanell Mestres, Joan; Ottensmeier, Christian; Arriola Aperribay, Edurne (Taylor & Francis, 2019)
    Background. Immunotherapy has shown efficacy in small cell lung cancer (SCLC), but only a subset of patients benefits. Surrogate biomarkers are urgently needed. Our aim was to evaluate serum Th1, Th2, and proinflammatory ...
  • Kuderna, Lukas F.K.; Solís Moruno, Manuel; Batlle Masó, Laura; Julià, Eva; Lizano, Esther; Anglada Busquets, Roger; Ramírez Bautista, Eva; Bote, Alex; Tormo, Marc; Marquès i Bonet, Tomàs, 1975-; Fornas Carreño, Oscar; Casals López, Ferran (Frontiers Media, 2020)
    Sorting of individual chromosomes by Flow Cytometry (flow-sorting) is an enrichment method to potentially simplify genome assembly by isolating chromosomes from the context of the genome. We have recently developed a ...

View more