• A systematic review of the effectiveness of adjuvant therapy for patients with gallbladder cancer

  Manterola, Carlos; Duque, Galo; Grande Posa, Luís; Aretxabala, Xabier de; Conejeros, Roque; Otzen, Tamara; García, Nayely (Elsevier, 2019)

  BACKGROUND: Equipoise exists regarding the benefit of adjuvant therapy (AT) in patients with gallbladder cancer (GBC). The aim of this study was to critically review the available evidence for the effectiveness of AT in ...
• The importance of adequate recognition of normal and dysplastic myelopoiesis for the diagnosis of myelodysplastic syndromes

  Florensa Brichs, Lourdes; Arenillas Rocha, Leonor; Calvo Gonzalo, Xavier; Pérez-Vila, Encarnación; Ferrer Del Alamo, Ana; Woessner, Soledad (Universidad de Murcia, 2019)

  The diagnosis of myelodysplastic syndromes is based on the presence of cytopenias, dysplastic morphological features on peripheral blood (PB) and bone marrow (BM), cytogenetic abnormalities and requires to rule out other ...
• Autologous stem cell transplantation may be curative for patients with follicular lymphoma with early therapy failure without the need for immunotherapy

  Salar Silvestre, Antonio; Jiménez-Ubieto, Ana; Lahuerta, Juan José; GELTAMO group (Elsevier, 2019)

  Objective/background: Patients with follicular lymphoma (FL) with early therapy failure (ETF) within 2 years of frontline therapy have poor overall survival (OS). We recently reported the results of autologous stem cell ...
• Incidence of sleep apnea and association with atrial fibrillation in an unselected pacemaker population: results of the observational RESPIRE study

  Martí Almor, Julio; Marques, Pedro; Jesel, Laurence; García, Rodrigue; Di Girolamo, Enrico; Locati, Fabio; Defaye, Pascal; Venables, Paul; Dompnier, Antoine; Barceló, Aina; Burr, Haran (Elsevier, 2019)

  Background: Patients with atrial fibrillation (AF) often have sleep apnea (SA), but diagnosis of SA with polysomnography is costly. SA monitoring is a pacemaker feature that measures respiratory disturbance index, the sum ...
• ITEMAS ontology for healthcare technology innovation

  Moreno-Conde, A.; Parra-Calderón, C.L.; Sánchez-Seda, S.; Escobar-Rodríguez, G. A.; López Otero, Marta; Cussó, L.; Del-Cerro-García, R.; Segura-Sánchez, M.; Herrero-Urigüen, L.; Martí-Ras, N.; Albertí-Ibarz, M.; Desco, Manuel (BioMed Central, 2019)

  Background: The Platform for Innovation in Medical and Health Technologies (ITEMAS) is a network of 66 healthcare centres focused on fostering innovation in medical and health technologies as an essential tool for increasing ...
• Determining the health benefits of green space: does gentrification matter?

  Cole, Helen; Garcia Lamarca, Melisa; Triguero Mas, Margarita, 1985-; Connolly, James; Anguelovski, Isabelle (Elsevier, 2019)

  Urban green space is demonstrated to benefit human health. We evaluated whether neighborhood gentrification status matters when considering the health benefits of green space, and whether the benefits are received equitably ...
• Psychometric properties of the spanish version of the once-daily urticaria activity score (UAS) in patients with chronic spontaneous urticaria managed in clinical practice (The EVALUAS Study)

  Jauregui, Ignacio; Giménez Arnau, Anna Maria; Bartra, Joan; Labrador-Horrillo, Moises; Ortiz de Frutos, Javier; Silvestre, Juan Francisco; Sastre, Joaquin; Velasco, Manuel; Ferrer, Marta; Ballesteros, Cristina; Valero, Antonio (BioMed Central, 2019)

  BACKGROUND: The daily diary Urticaria Activity Score (UAS) and its weekly score (UAS7) are widely used to assess signs and symptoms in patients with chronic spontaneous urticaria (CSU). The objective of this study was to ...
• Treatment of chronic spontaneous urticaria with an inadequate response to H1-antihistamine

  Curto-Barredo, Laia; Giménez Arnau, Anna Maria (Edizione Minerva Medica, 2019)

  The second-generation H1-antihistamines (sgAH) are the first-line symptomatic treatment of patients with chronic spontaneous urticaria (CSU). Up to 50% of the patients will not respond to licensed doses of sgAH. According ...
• Disease-modifying effects of natural Δ9-tetrahydrocannabinol in endometriosis-associated pain

  Escudero-Lara, Alejandra; Argerich, Josep; Cabañero Ferri, David; Maldonado, Rafael, 1961- (Elife Science Publications, 2020)

  Endometriosis is a chronic painful disease highly prevalent in women that is defined by growth of endometrial tissue outside the uterine cavity and lacks adequate treatment. Medical use of cannabis derivatives is a current ...
• Costes sanitarios de las enfermedades profesionales: análisis de una serie de pacientes de un hospital público

  Serra, Consol; Valiño-Carrete, Mery; Cots Reguant, Francesc; Trapero-Bertran, Marta; Benavides, Fernando G. (Fernando García) (Societat Catalana de Salut Laboral y Asociación de Medicina del Trabajo de la Comunidad Valenciana, 2019)

  El infra-reconocimiento secular de las enfermedades profesionales (EP) en España provoca un intercambio de pacientes y recursos entre el Sistema Nacional de Salud y el de Seguridad Social. Se estimaron los costes asistenciales ...
• Association between the big five factors of personality and survival seven years after heart transplantation

  Sánchez-González, Roberto; Rodríguez-Urrutia, Amanda; Monteagudo-Gimeno, Eila; Herranz-Villanueva, Sandra; Pérez-Villa, Félix; Pintor-Pérez, Luis (Elsevier, 2019)
• Editorial: present and future of EMDR in clinical psychology and psychotherapy

  Castelnuovo, Gianluca; Fernández, Isabel; Amann, Benedikt Lorenz (Frontiers, 2019)
• A multicenter phase II rater-blinded randomized controlled trial to compare the effectiveness of eye movement desensitization reprocessing therapy vs. treatment as usual in patients with substance use disorder and history of psychological trauma: a study design and protocol

  Valiente Gómez, Alicia; Moreno Alcázar, Ana; Radua, Joaquim; Hogg, Bridget; Blanco Hinojo, Laura, 1981-; Lupo, Walter; Pérez Solá, Victor; Robles-Martínez, María; Torrens, Marta; Amann, Benedikt Lorenz (Frontiers, 2019)

  Background: Psychological trauma has a strong negative impact on the onset, course and prognosis of substance use disorders (SUD). Few trauma-oriented treatment approaches have been trialed, but preliminary evidence exists ...
• Mood disorders and severity of addiction in alcohol-dependent patients could be mediated by sex differences

  Robles-Martínez, María; Palma-Álvarez, Raul F.; Rodríguez-Cintas, Laia; Abad, Alfonso C.; Sorribes, Marta; Ros-Cucurull, Elena; Robles-Martínez, María; Grau-López, Lara; Aguilar, Lourdes; Roncero, Carlos (Frontiers, 2019)

  Background: Alcohol dependence is highly prevalent in the general population; some differences in alcohol use and dependence between women and men have been described, including outcomes and ranging from biological to ...
• Clinical presentations and outcomes related to tuberculosis in children younger than 2 years of age in Catalonia

  Soriano-Arandes, Antoni; López Segura, María Nuria; Caylà i Busqueras, Joan A. (Frontiers, 2019)

  Introduction: Children younger than 2 years have an increased risk of complications associated with tuberculosis (TB) due to the immaturity of the innate and adaptive immune response. We aimed to identify TB clinical ...
• A combined transcriptomic and genomic analysis identifies a gene signature associated with the response to anti-TNF therapy in rheumatoid arthritis

  Aterido, Adrià; Cañete Crespillo, Juan de Dios; Tornero, Jesús; Blanco, Francisco; Fernández-Gutiérrez, Benjamín; Pérez-García, Carolina; Alperiz, Mercedes; Olivé, Alex; Corominas, Héctor; Martínez-Taboada, Víctor; González-Alvaro, Isidoro; Fernández-Nebro, Antonio; Erra, Alba; López Lasanta, María; López Corbeto, Mireia; Palau, Núria; Marsal, Sara; Julià, Antonio (Frontiers, 2019)

  Background: Rheumatoid arthritis (RA) is the most frequent autoimmune disease involving the joints. Although anti-TNF therapies have proven effective in the management of RA, approximately one third of patients do not show ...
• COPD: preclinical models and emerging therapeutic targets

  Barreiro Portela, Esther; Wang, Xuejie; Tang, Jun (Informa Healthcare, 2019)

  Introduction: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Preclinical models of COPD have recently been developed. In those models, COPD/emphysema has been commonly ...
• Immunotherapy in non-metastatic urothelial cancer: back to the 'future'

  Darling, H. S.; Bellmunt Molins, Joaquim, 1959- (Taylor & Francis, 2019)

  INTRODUCTION: Successful results of immuno-oncological drugs in metastatic urothelial cancer have triggered the interest of researchers to test them in the non-metastatic setting. Conventional treatment modalities in that ...
• Safe use of immune checkpoint inhibitors in the multidisciplinary management of urological cancer: the european association of urology position in 2019

  Grimm, Marc-Oliver; Bex, Axel; De Santis, Maria; Ljunberg, Börje; Catto, James W.F.; Rouprêt, Morgan; Hussain, Syed; Bellmunt Molins, Joaquim, 1959-; Powles, Thomas; Wirth, Manfred; Van Poppel, Hendrik (Elsevier, 2019)

  Immune checkpoint inhibitors (ICIs) are now used routinely to treat advanced or metastatic urothelial and renal cell carcinoma, among other cancers. Furthermore, multiple trials are currently exploring their role in adjuvant, ...
• Plasma androgen receptor and docetaxel for metastatic castration-resistant prostate cancer

  Conteduca, Vincenza; Rodríguez-Vida, Alejo; De Giorgi, Ugo (Elsevier, 2019)

  Plasma androgen receptor (AR) gain identifies metastatic castration-resistant prostate cancer (mCRPC) patients with worse outcome on abiraterone/enzalutamide, but its relevance in the context of taxane chemotherapy is ...

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