• Restrictive spirometry pattern is associated with low physical activity levels. A population based international study

  Carsin, Anne-Elie; Fuertes, Elaine; Antó i Boqué, Josep Maria; Guerra, Stefano; García Aymerich, Judith (Elsevier, 2019)

  Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with ...
• Effects of virgin olive oils differing in their bioactive compound contents on biomarkers of oxidative stress and inflammation in healthy adults: a randomized double-blind controlled trial

  Sánchez-Rodriguez, Estefanía; Biel-Glesson, Sara; Fernández-Navarro, Jose-Ramón; Calleja, Miguel Angel; Espejo-Calvo, Juan A.; Gil-Extremera, Blas; Torre Fornell, Rafael de la; Fitó Colomer, Montserrat; Covas Planells, Maria Isabel; Vilchez, Pedro; Alche, Juan de Dios; Martínez de Victoria, Emilio; Gil, Angel; Mesa, Maria-Dolores (MDPI, 2019)

  A regular consumption of virgin olive oil (VOO) is associated with a reduced risk of cardiovascular disease. We aimed to assess whether the raw intake of an optimized VOO (OVOO, 490 ppm of phenolic compounds and 86 ppm of ...
• Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis

  Gruzieva, Olena; Kogevinas, Manolis; Ruiz, José L.; Bustamante Pineda, Mariona; Antó i Boqué, Josep Maria; Sunyer Deu, Jordi; Vrijheid, Martine; Hernandez-Ferrer, Carles, 1987-; Melén, Erik (National Institute of Environmental Health Sciences (NIEHS), 2019)

  BACKGROUND: Prenatal exposure to air pollution has been associated with childhood respiratory disease and other adverse outcomes. Epigenetics is a suggested link between exposures and health outcomes. OBJECTIVES: We aimed ...
• Urine metabolic signatures of multiple environmental pollutants in pregnant women: an exposome approach

  Maitre, Léa; Robinson, Oliver; Martínez, David; Toledano, Mireille B.; Ibarluzea, Jesús; Marina, Loreto Santa; Sunyer Deu, Jordi; Villanueva, Cristina M.; Keun, Hector C.; Vrijheid, Martine; Coen, Muireann (American Chemical Society (ACS), 2018)

  Exposure to environmental pollutants, particularly during pregnancy, can have adverse consequences on child development but little is known about the effects of pollutant mixtures on endogenous metabolism in pregnant women. ...
• Long-term exposure to residential green and blue spaces and anxiety and depression in adults: A cross-sectional study

  Gascon Merlos, Mireia, 1984-; Sánchez Benavides, Gonzalo; Dadvand, Payam; Martínez, David; Gramunt Fombuena, Nina; Gotsens, Xavier; Cirach, Marta; Vert, Cristina; Molinuevo, José Luis; Crous-Bou, Marta; Nieuwenhuijsen, Mark J. (Elsevier, 2018)

  Background: Although exposure to natural outdoor environments has been consistently associated with improved perceived general health, available evidence on a protective association between this exposure and specific mental ...
• Long-term exposure to trihalomethanes in drinking water and breast cancer in the Spanish multicase-control study on cancer (MCC-SPAIN)

  Font Ribera, Laia; Gràcia Lavedan, Esther; Castaño Vinyals, Gemma; Kogevinas, Manolis; Villanueva, Cristina M. (Elsevier, 2018)

  Background: Exposure to trihalomethanes (THMs) in drinking water has consistently been associated with an increased risk of bladder cancer, but evidence on other cancers including the breast is very limited. Objectives: ...
• Drinking water disinfection by-products during pregnancy and child neuropsychological development in the INMA Spanish cohort study

  Villanueva, Cristina M.; Gracia Lavedan, Esther; Julvez, Jordi; Santa Marina, Loreto; Lertxundi, Nerea; Ibarluzea, Jesús; Llop, Sabrina; Ballester Díez, Ferran; Fernández Somoano, Ana; Tardón, Adonina; Vrijheid, Martine; Guxens Junyent, Mònica; Sunyer Deu, Jordi (Elsevier, 2018)

  Background: Disinfection by-products (DBPs) constitute a complex mixture of prevalent chemicals in drinking water and there is evidence of neurotoxicity for some of them. Objectives: We evaluated the association between ...
• Current controversies in the stepping up and stepping down of inhaled therapies for COPD at the patient level

  Lopez-Campos, Jose Luis; Carrasco Hernández, Laura; Muñoz, Xavier; Bustamante, Víctor; Barreiro Portela, Esther (Wiley, 2018)

  The implementation of potential new step-up or step-down treatment recommendations in response to current guidelines is one of the main challenges currently faced in actual daily practice settings. In the present narrative ...
• Reply to «Influenza vaccination and critical patient protection: responsibility of healthcare workers»

  Marin Corral, Judith; Muñoz Bermudez, Rosana; Álvarez Lerma, Francisco (Elsevier, 2019)
• Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer

  Walsh, Naomi; Porta Serra, Miquel; Real, Francisco X.; Stolzenberg-Solomon, Rachael Z. (Oxford University Press, 2018)

  Genome-wide association studies (GWAS) identify associations of individual single-nucleotide polymorphisms (SNPs) with cancer risk but usually only explain a fraction of the inherited variability. Pathway analysis of genetic ...
• Rituximab treatment Of Pemphigus Foliaceus- A Retrospective Study Of 12 Patients

  Palacios-Álvarez, Irene; Riquelme-Mc Loughlin, Constanza; Curto-Barredo, Laia; Iranzo, Pilar; García-Díez, Irene; España, Agustín (Elsevier, 2018)
• Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial

  Jiménez-Marrero, Santiago; Yun, Sergi; Cainzos-Achirica, Miguel; Enjuanes Grau, Cristina; Garay, Alberto; Farré López, Núria; Verdú-Rotellar, José María; Linas Alonso, Ana Maria; Ruiz-Rodriguez, María del Pilar; Hidalgo, Encarnacion; Calero; Esther; Comín Colet, Josep (SAGE Publications, 2018)

  Background The efficacy of telemedicine in the management of patients with chronic heart failure and left ventricular ejection fraction ≥40% is poorly understood. The aim of our analysis was to evaluate the efficacy of a ...
• Residential proximity to green spaces and breast cancer risk: The multicase-control study in Spain (MCC-Spain)

  O'Callaghan Gordo, Cristina; Kogevinas, Manolis; Cirach, Marta; Castaño Vinyals, Gemma; Gràcia Lavedan, Esther; Espinosa Díaz, Ana; Valentín, Antònia; Nieuwenhuijsen, Mark J. (Elsevier, 2018)

  Background: Breast cancer is the main cause of cancer mortality among women. Green spaces have been recently associated with reduced cancer mortality among women. Mechanisms explaining the beneficial effect of green spaces ...
• Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete)

  O’Callaghan-Gordo, Cristina; Kogevinas, Manolis; Pedersen, Marie; Espinosa Díaz, Ana; Tsiapa, Xristina; Romaguera Bosch, Dora; Chatzi, Leda (Springer, 2018)

  Purpose: The study assessed whether diet and adherence to cancer prevention guidelines during pregnancy were associated with micronucleus (MN) frequency in mothers and newborns. MN is biomarkers of early genetic effects ...
• Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine

  Martínez-Sánchez, Jose M.; Ballbé, Montse; Pérez-Ortuño, Raúl; Fu, Marcela; Sureda, Xisca; Pascual Esteban, José A.; Peruga, Armando; Fernández, Esteve (Elsevier, 2018)

  OBJECTIVE: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). METHOD: We conducted ...
• Determinantes sociales y clínicos del uso de servicios sanitarios en mujeres con cáncer de mama (Cohorte DAMA)

  Puigpinós i Riera, Rosa; Castillo Gómez, Adán; Romero, Anabel; Aller, Marta-Beatriz; Castells, Xavier; Sala Serra, Maria; Grupo Cohort Dama (Elsevier, 2018)

  OBJECTIVE: To describe and analyse the factors associated with the use of health services (emergency departments, admissions and primary care) in women survivors of breast cancer diagnosed or treated in four university ...
• EUROVISCO Recommendations for Optimizing the Clinical Results of Viscosupplementation in Osteoarthritis

  Conrozier, Thierry; Monfort Faure, Jorge; Chevalier, Xavier; Raman, Raghu; Richette, Pascal; Diraçoglù, Demirhan; Bard, Hervé; Baron, Dominique; Jerosch, Jörg; Migliore, Alberto; Henrotin, Yves (SAGE Publications, 2018)

  Objectives The 3 aims of the work were to identify population subgroups that can benefit the most from viscosupplementation (VS), to provide recommendations on injection techniques, and to discuss VS appropriateness in ...
• Impacto de los factores de riesgo cardiovascular en la población extremeña: aportación de la cohorte HERMEX para una estrategia preventiva

  Félix-Redondo, Francisco Javier; Lozano Mera, Luis; Álvarez-Palacios Arrighi, Paula; Grau Magaña, Maria; Ramírez-Romero, Jose María; Fernández-Bergés, Daniel (Elsevier, 2019)

  OBJECTIVE: To determine the population attributable fraction (PAF) of the major risk factors (RF) for the occurrence of cardiovascular disease in an Extremadura population cohort and therefore recommend priority preventive ...
• Oil extraction in the Amazon basin and exposure to metals in indigenous populations

  O'Callaghan Gordo, Cristina; Flores, Juan A.; Lizárraga, Pilar; Okamoto, Tami; Papoulias, Diana M.; Barclay, Federica; Orta-Martínez, Martí; Kogevinas, Manolis; Astete, John (Elsevier, 2018)

  Most oil extraction areas in the Peruvian Amazon are within indigenous territories. Poor environmental practices have exposed the indigenous population to metals. We conducted a survey in two indigenous Kukama communities ...
• Cerebral small vessel disease: a review focusing on pathophysiology, biomarkers, and machine learning strategies

  Cuadrado Godia, Elisa; Dwivedi, Pratistha; Sharma, Sanjiv; Ois Santiago, Angel Javier; Roquer, Jaume; Balcells, Mercedes; Laird, John; Turk, Monika; Suri, Harman S.; Nicolaides, Andrew; Saba, Luca; Khanna, Narendra N.; Suri, Jasjit S. (Korean Stroke Society, 2018)

  Cerebral small vessel disease (cSVD) has a crucial role in lacunar stroke and brain hemorrhages and is a leading cause of cognitive decline and functional loss in elderly patients. Based on underlying pathophysiology, cSVD ...

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