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Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM))

Articles (Institut Hospital del Mar d'Investigacions Mèdiques (IMIM))

 

Recent Submissions

  • Ordi, Jaume (Public Library of Science (PLoS), 2019)
    Background: Clinico-pathological discrepancies are more frequent in settings in which limited diagnostic techniques are available, but there is little information on their actual impact. Aim: We assessed the accuracy of ...
  • Maseda, Emilio; Ramírez, Sofía; Picatto, Pedro; Peláez-Peláez, Eva; García-Bernedo, Carlos A.; Ojeda-Betancur, Nazario; Aguilar, Gerardo; Forés, Beatriz; Solera-Marín, Jorge; Aliaño-Piña, María; Tamayo Aguirre, Eduardo; Ramasco, Fernando; García-Álvarez, Raquel; González-Lisorge, Ada; Giménez, Maria-José; Suárez-de-la-Rica, Alejandro; HELP Investigators and the Perioperative Infection Research Group (Public Library of Science (PLoS), 2019)
    The concept of healthcare-associated infections (as opposed to hospital-acquired infections) in intraabdominal infections (IAIs) is scarcely supported by data in the literature. The aim of the present study was to analyse ...
  • Llauradó Cabot, Gemma; Cano, Albert; Albert, Lara; Ballesta, Silvia; Mazarico, Isabel; Luchtenberg, María-Florencia; González Sastre, Montserrat; Megia, Ana; Simó, Rafael; Vendrell, Joan; González Clemente, José (Public Library of Science (PLoS), 2019)
    Objectives: Currently used risk scores for type 2 diabetes mellitus (T2DM) clearly underestimate cardiovascular risk in type 1 diabetes (T1DM). Hence, there is a need to develop novel and specific risk-estimation tools for ...
  • Hernáez, Álvaro; Soria-Florido, Maria; Schröder, Helmut, 1958-; Ros, Emilio; Pinto, Xavier; Estruch, Ramón; Salas-Salvadó, Jordi; Corella, Dolores; Arós, Fernando; Serra-Majem, Luis; Martínez-González, Miguel A.; Fiol, Miquel; Lapetra, José; Elosua Llanos, Roberto; Lamuela-Raventós, Rosa M.; Fitó Colomer, Montserrat (Public Library of Science (PLoS), 2019)
    Background: High-density lipoprotein (HDL) functionality and low-density lipoprotein (LDL) atherogenic traits can describe the role of both particles on cardiovascular diseases more accurately than HDL- or LDL-cholesterol ...
  • Boyce, Alison M.; Casey, Rachel K.; Ovejero Crespo, Diana; Murdock, Cynthia M.; Estrada, Andrea; Guthrie, Lori C.; Brillante, Beth A.; Gomez-Lobo, Veronica; Nieman, Lynette K.; Collins, Michael T. (BioMed Central, 2019)
    Background: Autonomous ovarian activation with recurrent estrogen-producing cysts is a hallmark feature of the rare bone and endocrine disorder fibrous dysplasia/McCune-Albright syndrome. Precocious puberty in girls with ...
  • Ruiz-Arenas, Carlos; Cáceres, Alejandro; López Sánchez, Marcos, 1986-; Tolosana, Ignacio; Pérez Jurado, Luis Alberto; González Ruiz, Juan Ramón (Public Library of Science (PLoS), 2019)
    Polymorphic inversions contribute to adaptation and phenotypic variation. However, large multi-centric association studies of inversions remain challenging. We present scoreInvHap, a method to genotype inversions from SNP ...
  • Ciruelos, Eva; Alba, Emilio; López, Rafael; Lluch, Ana; Martín, Miguel; Arroyo, Isabel; Navarro, Beatriz; Carcedo, David; Colomer, Ramon; Albanell Mestres, Joan (Impact Journals, 2019)
    Introduction: Trastuzumab has become the standard treatment for both HER2-positive early and metastatic breast cancer (HER2+ eBC or mBC) since its approval. The objective of the study is to estimate the benefit of adjuvant ...
  • Buxeda, Anna; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Bartolomé, Álvaro; Mir Fontana, M. Luisa; Pascual-Dapena, Ana; Sans, Anna; Duran Jordà, Xavier, 1974-; Crespo Barrio, Marta; Pascual Santos, Julio (Impact Journals, 2019)
    Kidney transplant (KT) recipients are at greater risk of developing some cancers than the general population. Moreover, cancer is the only cause of death that is currently increasing after kidney transplantation. We analyzed ...
  • Costa, Dolors; Grau, Javier; Espinet Solà, Blanca; Arias, Amparo; Gómez, Cándida; López-Guerra, Mónica; Nomdedeu, Meritxell; Cervantes, Francisco (Spandidos Publications, Ltd., 2019)
    BCR/ABL1 gene fusion is the hallmark of chronic myeloid leukemia (CML), and is generated in 5-10% of patients by a variant translocation involving 9q34, 22q11.2 and one or more additional genomic regions. The objective of ...
  • Cebrià i Costa, Joan Pau, 1989-; Pascual-Reguant, Laura; Gonzalez-Perez, Abel; Serra-Bardenys, Gemma; Querol, J.; Cosín, M.; Verde, Gaetano; Cigliano, R. A.; Sanseverino, Walter; Segura-Bayona, Sandra; Iturbide Martínez de Albéniz, Ane, 1989-; Andreu Martínez, David; Nuciforo, Paolo G.; Bernado-Morales, C.; Rodilla, Verónica; Arribas, Joaquín; Yelamos López, Jose; García de Herreros, Antonio; Stracker, Travis; Peiró Sales, Sandra (Nature Research, 2020)
    Oxidation of H3 at lysine 4 (H3K4ox) by lysyl oxidase-like 2 (LOXL2) generates an H3 modification with an unknown physiological function. We find that LOXL2 and H3K4ox are higher in triple-negative breast cancer (TNBC) ...
  • Oliveras, Anna; Goday Arno, Alberto; Sans Atxer, Laia; Vázquez, Susana; Benaiges Foix, David; Ramón Moros, José Manuel; Pascual Santos, Julio (Springer, 2020)
    Background: Weight loss is associated to blood pressure (BP) reduction in obese patients. There is no information on central 24-h BP changes after bariatric surgery (BS). Methods and results: In this study, we analyzed ...
  • Hardy-Werbin, Max; Rocha, Pedro P.; Arpí Llucià, Oriol; Taus García, Álvaro; Nonell Mazelón, Lara; Duran Jordà, Xavier, 1974-; Villanueva, Xavier; Joseph-Pietras, Deborah; Nolan, Luke; Danson, Sarah; Griffiths, Richard; López-Botet, M. (Miguel); Rovira Guerín, Ana; Albanell Mestres, Joan; Ottensmeier, Christian; Arriola Aperribay, Edurne (Taylor & Francis, 2019)
    Background. Immunotherapy has shown efficacy in small cell lung cancer (SCLC), but only a subset of patients benefits. Surrogate biomarkers are urgently needed. Our aim was to evaluate serum Th1, Th2, and proinflammatory ...
  • Kuderna, Lukas F.K.; Solís Moruno, Manuel; Batlle Masó, Laura; Julià, Eva; Lizano, Esther; Anglada Busquets, Roger; Ramírez Bautista, Eva; Bote, Alex; Tormo, Marc; Marquès i Bonet, Tomàs, 1975-; Fornas Carreño, Oscar; Casals López, Ferran (Frontiers Media, 2020)
    Sorting of individual chromosomes by Flow Cytometry (flow-sorting) is an enrichment method to potentially simplify genome assembly by isolating chromosomes from the context of the genome. We have recently developed a ...
  • Bazal, P.; Gea, Alfredo; Martínez-González, Miguel Ángel; Salas-Salvadó, Jordi; Asensio, E. M.; Muñoz-Bravo, Carlos; Fiol, Miquel; Muñoz, Miguel Ángel; Lapetra, José; Serra-Majem, Luis; Pinto, Xavier; González, José I.; Becerra-Tomás, Nerea; Fitó Colomer, Montserrat; Ros, Emilio; Alonso-Gómez, Ángel; Ruiz-Canela, Miguel (Elsevier, 2019)
    Background and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol ...
  • Vitelli Storelli, Facundo; Kogevinas, Manolis; Martín, Vicente (MDPI, 2019)
    Several epidemiological studies have investigated the association between the dietary flavonoid intake and gastric cancer (GC) risk; however, the results remain inconclusive. Investigating the relationship between the ...
  • Li, Zhen; Leynaert, Bénédicte; Dumas, Orianne; Díaz Gil, Oscar; García Aymerich, Judith; Fitó Colomer, Montserrat; Le Moual, Nicole; Pison, Christophe; Romieu, Isabelle; Siroux, Valérie; Camargo, Carlos A.; Varraso, Raphaëlle; Nadif, Rachel (Wiley, 2019)
    Objective: Obesity is a likely risk factor for asthma. However, underlying mechanisms by which obesity affects asthma activity remain poorly understood. This study aimed to investigate the role of leptin, an adipocyte-derived ...
  • Vázquez, Alejandra; Sánchez-Rodriguez, Estefanía; Vargas, Félix; Montoro-Molina, Sebastián; Romero-Cuevas, Miguel; Espejo, Juan-Antonio; Vilchez, Pedro; Jaramillo, Sara; Olmo-García, Lucía; Carrasco-Pancorbo, Alegría; Torre Fornell, Rafael de la; Fitó Colomer, Montserrat; Covas Planells, Maria Isabel; Martínez de Victoria, Emilio; Mesa, Maria-Dolores (MDPI, 2019)
    Olive oil and its derivatives have been described to exert beneficial effects on hypertensive states and cardiovascular disease prevention. We studied the effects of chronic consumption of extra virgin olive oil (EVOO), ...
  • Prieto, Rafael M.; Rodríguez, Adrian; Sanchís, Pilar; Morey, Marga; Fiol, Miquel; Grases, Félix; Castañer, Olga; Martínez-González, Miguel A.; Salas-Salvadó, Jordi; Romaguera, Dora (MDPI, 2019)
    Our purpose was to study the relationship of adherence to the Mediterranean diet (MedDiet) with urinary factors that favor the formation of renal calcium and uric acid stones in overweight and obese participants who had ...
  • Olmedo-Requena, Rocío; Castaño Vinyals, Gemma; Kogevinas, Manolis; Martín Sánchez, Vicente (MDPI, 2019)
    There are many different methods used to measure the degree of adherence to a Mediterranean diet (MD), limiting comparison and interpretation of their results. The concordance between different methodologies has been ...
  • Papandreou, Christopher; Fitó Colomer, Montserrat; Salas Salvadó, Jordi (MDPI, 2019)
    Few studies have examined the association of a wide range of metabolites with total and subtypes of coffee consumption. The aim of this study was to investigate associations of plasma metabolites with total, caffeinated, ...

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