• Transcriptomic differences in MSA clinical variants

  Pérez Soriano, Alexandra; Arnal, Magdalena; Botta Orfila, Teresa; Giraldo, Darly; Fernández, Manel; Compta, Yaroslau; Fernández-Santiago, Ruben; Ezquerra, Mario; Tartaglia, Gian Gaetano; Martí, M. Josep; Catalan multiple system atrophy-registry (CMSAR) (Nature Research, 2020)

  Background: Multiple system atrophy (MSA) is a rare oligodendroglial synucleinopathy of unknown etiopathogenesis including two major clinical variants with predominant parkinsonism (MSA-P) or cerebellar dysfunction (MSA-C). ...
• COVID-19 y la neumología del siglo XXI: ¿reto u oportunicad?

  Barreiro Portela, Esther; Jiménez, Carlos; García de Pedro, Julia; Ramírez Prieto, María Teresa (Elsevier, 2020)
• Correction: use of health apps by nurses for professional purposes: web-based survey study

  Mayer, Miguel Ángel, 1960- (JMIR Publications Inc., 2019)
• Improved diagnosis of rare disease patients through systematic detection of runs of homozygosity

  Matalonga, Leslie; Laurie, Steven; Papakonstantinou, Anastasios; Piscia, Davide; Mereu, Elisabetta; Bullich, Gemma; Thompson, Rachel; Horvath, Rita; Pérez Jurado, Luis Alberto; Riess, Olaf; Gut, Ivo; van Ommen, Gert-Jan; Lochmüller, Hanns; Beltran, Sergi; RD–Connect Genome-Phenome Analysis Platform and URD-Cat Data Contributors (Elsevier, 2020)

  Autozygosity is associated with an increased risk of genetic rare disease, thus being a relevant factor for clinical genetic studies. More than 2400 exome sequencing data sets were analyzed and screened for autozygosity ...
• Bioavailability of epigallocatechin gallate administered with different nutritional strategies in healthy volunteers

  Andreu-Fernández, Vicente; Almeida Toledano, Laur; Pizarro Lozano, Mª Nieves; Navarro-Tapia, Elisabet; Gómez-Roig, María Dolores; Torre Fornell, Rafael de la; García-Algar, Oscar (MDPI, 2020)

  The flavanol epigallocatechin gallate (EGCG) is being tested for the treatment of several diseases in humans. However, its bioavailability and pharmacokinetic profile needs a better understanding to enable its use in ...
• Amyloid beta, tau, synaptic, neurodegeneration, and glial biomarkers in the preclinical stage of the Alzheimer's continuum

  Milà Alomà, Marta; Salvadó, Gemma; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; Grau-Rivera, Oriol; Sala Vila, Aleix; Sánchez Benavides, Gonzalo; Arenaza Urquijo, Eider M.; Crous-Bou, Marta; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Simon, Maryline; Kollmorgen, Gwendlyn; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Molinuevo, José Luis; ALFA Study (Wiley, 2020)

  Introduction: The biological pathways involved in the preclinical stage of the Alzheimer's continuum are not well understood. Methods: We used NeuroToolKit and Elecsys® immunoassays to measure cerebrospinal fluid (CSF) ...
• ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020)

  Bousquet, Jean; Antó i Boqué, Josep Maria; Agache, Ioana (Wiley, 2020)
• Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: the ENIGMA adventure

  Hoogman, Martine; Vilarroya, Óscar; Franke, Barbara (Wiley, 2020)

  Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main ...
• Epigenomic assessment of cardiovascular disease risk and interactions with traditional risk metrics

  Westerman, Kenneth; Fernández Sanlés, Alba; Patil, Prasad; Sebastiani, Paola; Jacques, Paul; Starr, John M.; Deary ,Ian J.; Liu, Qing; Liu, Simi; Elosua Llanos, Roberto; DeMeo, Dawn L; Ordovás, José M. (Wiley-Blackwell, 2020)

  Background Epigenome-wide association studies for cardiometabolic risk factors have discovered multiple loci associated with incident cardiovascular disease (CVD). However, few studies have sought to directly optimize a ...
• Pharmacokinetics/pharmacodynamics of antiviral agents used to treat SARS-CoV-2 and their potential interaction with drugs and other supportive measures: a comprehensive review by the PK/PD of anti-infectives study group of the European Society of Antimicrobial Agents

  Zeitlinger, Markus; Koch, Birgit C.P.; Bruggemann, Roger; De Cock, Pieter; Felton, Timothy; Hites, Maya; El, Jennifer; Luque Pardos, Sònia; MacGowan, Alasdair P.; Marriott, Deborah J. E.; Muller, Anouk E.; Nadrah, Kristina; Paterson, David L.; Standing, Joseph F.; Telles, João P.; Wölfl-Duchek, Michael; Thy, Michael; Roberts, Jason A.; PK/PD of Anti-Infectives Study Group (EPASG) of the European Society of Clinical Microbiology, Infectious Diseases (ESCMID) (SpringerOpen, 2020)

  There is an urgent need to identify optimal antiviral therapies for COVID-19 caused by SARS-CoV-2. We have conducted a rapid and comprehensive review of relevant pharmacological evidence, focusing on (1) the pharmacokinetics ...
• NeuroHeal reduces muscle atrophy and modulates associated autophagy

  Marmolejo-Martínez-Artesero, Sara; Romeo-Guitart, David; Mañas-García, Laura; Barreiro Portela, Esther; Casas, Caty (MDPI, 2020)

  Muscle wasting is an unmet medical need which leads to a reduction of myofiber diameter and a negative impact on the functional performance of daily activities. We previously found that a new neuroprotective drug called ...
• Hospital-at-home as an alternative to release the overload of healthcare systems during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic

  Arias-de la Torre, Jorge; Alonso Caballero, Jordi; Martín, Vicente; Valderas Martínez, José María (Elsevier, 2020)
• Do birthrates contribute to sickness absence differences in women? A cohort study in Catalonia, Spain, 2012-2014

  March, Andrew N.; Villar Vinuesa, Rocío, 1976-; Ubalde López, Mònica, 1972-; Benavides, Fernando G. (Fernando García); Serra Saurina, Laura (Public Library of Science (PLoS), 2020)

  Aims: This study explores the differences in sickness absence trends in women according to reproductive age group and medical diagnoses. Methods: Data were obtained from two administrative registries: the Continuous Working ...
• Sickness absence trajectories following labour market participation patterns: a cohort study in Catalonia (Spain), 2012–2014

  Hernando-Rodriguez, Julio C.; Serra Saurina, Laura; Benavides, Fernando G. (Fernando García); Ubalde López, Mònica, 1972- (BioMed Central, 2020)

  Background: Previous studies have focused on the relationship between employment pathways and health-related outcomes based on cross-sectional or longitudinal approaches. However, little is known about the cumulative effects ...
• Circular DNA intermediates in the generation of large human segmental duplications

  Chicote, Javier U.; López Sánchez, Marcos, 1986-; Marquès i Bonet, Tomàs, 1975-; Callizo, José; Pérez Jurado, Luis Alberto; García-España, Antonio (BioMed Central, 2020)

  Background: Duplications of large genomic segments provide genetic diversity in genome evolution. Despite their importance, how these duplications are generated remains uncertain, particularly for distant duplicated genomic ...
• COVID-19: The disease of the Anthropocene

  O'Callaghan Gordo, Cristina; Antó i Boqué, Josep Maria (Elsevier, 2020)
• European task force on contact dermatitis statement on coronavirus disease-19 (COVID-19) outbreak and the risk of adverse cutaneous reactions

  Balato, Anna; Ayala, Fabio; Bruze, Magnus; Crepy, Marie-Noëlle; Gonçalo, Margarida; Johansen, JeanneDuus; John, Swen Malte; Pigatto, Paolo; Raimondo, Annunziata; Rustemeyer, Thomas; Schuttelaar, Marie-Louise A.; Svedman, Cecilia; Aerts, Olivier; Uter, Wolfgang; Wilkinson, Mark; Giménez Arnau, Anna Maria (Wiley, 2020)

  Among the basic protective measures against COVID-19, the need to wash hands frequently and in a prolonged way using soap, and to regularly use alcohol-based hand sanitizers is well established for the whole population.
• Short- and long-term mortality trends in STEMI-cardiogenic shock over three decades (1989-2018): the Ruti-STEMI-shock registry

  García-García, Cosme; Oliveras, Teresa; El Ouaddi, Nabil; Rueda, Ferran; Serra, Jordi; Labata, Carlos; Ferrer, Marc; Cediel, German; Montero, Santiago; Martínez, María José; Resta, Helena; de Diego, Oriol; Vila, Joan; Dégano, Irene R.; Elosua Llanos, Roberto; Lupón, Josep; Antoni Bayes-Genis (MDPI, 2020)

  Aims: Cardiogenic shock (CS) is an ominous complication of ST-elevation myocardial infarction (STEMI), despite the recent widespread use of reperfusion and invasive management. The Ruti-STEMI-Shock registry analysed the ...
• Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling

  Dwivedi, Hemlata; Chaturvedi, Madhu; Baidya, Mithu; Stepniewski, Tomasz Maciej, 1988-; Pandey, Shubhi; Maharana, Jagannath; Srivastava, Ashish; Caengprasath, Natarin; Hanyaloglu, Aylin C.; Selent, Jana; Shukla, Arun K. (American Association for the Advancement of Science (AAAS), 2020)

  Agonist-induced phosphorylation of G protein-coupled receptors (GPCRs) is a key determinant for their interaction with β-arrestins (βarrs) and subsequent functional responses. Therefore, it is important to decipher the ...
• Relationship between depression and the use of mobile technologies and social media among adolescents: umbrella review

  Arias-de la Torre, Jorge; Puigdomènech, Elisa; García, Xavier, 1967-; Valderas Martínez, José María; Eiroa-Orosa, Francisco José; Fernández-Villa, Tania; Molina, Antonio J.; Martín, Vicente; Serrano-Blanco, Antoni; Alonso Caballero, Jordi; Espallargues, Mireia (JMIR Publications, 2020)

  Background: Despite the relevance of mobile technologies and social media (MTSM) for adolescents, their association with depressive disorders in this population remains unclear. While there are previous reviews that have ...

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