• From physical to emotional pain in chronic kidney disease: nurses' perceptions

  Pedreira Robles, Guillermo; Aguayo-González, Mariela Patricia (Wiley-Blackwell, 2019)

  Background: Changes in body image are a recurring theme in the literature on chronic kidney disease (CKD). There is insufficient evidence identifying nurses' perceptions of this topic. Objective: To explore nurses' perceptions ...
• Propensity score methods in health technology assessment: principles, extended applications, and recent advances

  Ali, M. Sanni; Prieto-Alhambra, Daniel; Cruz Lopes, Luciane; Ramos, Dandara; Bispo, Nivea; Ichihara, Maria Y.; Pescarini, Julia M.; Williamson, Elizabeth; Fiaccone, Rosemeire L.; Barreto, Mauricio L.; Smeeth, Liam (Frontiers, 2019)

  Randomized clinical trials (RCT) are accepted as the gold-standard approaches to measure effects of intervention or treatment on outcomes. They are also the designs of choice for health technology assessment (HTA). ...
• Patellar tendon lengthening: rescue procedure for patella baja

  Perelli, Simone; Ibañez, Maximiliano; Morales-Marin, Carlos; Acuña-Avila, Gabriel; Espinoza-von Bischhoffshausen, Ricardo; Masferrer-Pino, Àngel; Monllau García, Juan Carlos (Elsevier, 2019)

  Patella baja is a challenging pathologic condition that causes pain and functional restrictions and can even lead to premature osteoarthritis-even more so in cases of patella infera or cases associated with degeneration ...
• Effect of the tumor suppressor miR-320a on viability and functionality of human osteosarcoma cell Llnes compared to primary osteoblasts

  Ugarte Corbalán, Laura de; Balcells, Susana; Güerri Fernández, Roberto; Grinberg, Daniel; Díez Pérez, Adolfo; Nogués Solan, Francesc Xavier; Garcia Giralt, Natàlia (MDPI, 2020)

  The miR-320a regulates a number of genes involved in various physiological processes. In particular, it has been reported as a tumor suppressor in several types of human cancers and involved in osteoporotic fracture and ...
• Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF)

  Hiligsmann, M.; Diez-Pérez, Adolfo; Reginster, J.Y. (Springer, 2020)

  Many patients at increased risk of fractures do not take their medication appropriately, resulting in a substantial decrease in the benefits of drug therapy. Improving medication adherence is urgently needed but remains ...
• Recomendaciones para la detección, diagnóstico y seguimiento de los pacientes con enfermedad por hígado graso no alcohólico en atención primaria y hospitalaria

  Caballeria, Llorenc; Augustin, Salvador; Broquetas, Teresa; Morillas, Rosa M.;; Vergara, Mercè; Virolés, Silvia; Hernández, Mª Rosario; Serra, Isabel; Goday Arno, Alberto; Vila, Lluis; Siso-Almirall, Antonio; Solans, Rosa; Fernández Real, Jose M.; Carrión Rodríguez, José Antonio; Graupera, Isabel; Ginès, Pere (Elsevier, 2019)

  La enfermedad por hígado graso no alcohólico (EHGNA) es una de las enfermedades hepáticas crónicas más frecuentes, con una prevalencia del 20-30% en la población general y del 60-80% en poblaciones de riesgo. En un porcentaje ...
• An open-source android application to measure anterior-posterior knee translation

  Serrancolí, Gil; Bogatikov, Peter; Tanyà Palacios, Guillem; Torner, Jordi; Monllau García, Juan Carlos; Perelli, Simone (MDPI, 2020)

  There are widely used standard clinical tests to estimate the instability of an anterior cruciate ligament (ACL) deficient knee by assessing the translation of the tibia with respect to the femur. However, the assessment ...
• Modification of the hybrid anatomic technique for anterior cruciate ligament reconstruction in pediatric patients

  Erquicia, Juan Ignacio; Ibañez, Maximiliano; Espinoza-Von Bischhoffshausen, Ricardo; Acuña, Gabriel; Pelfort López, Javier; Monllau García, Juan Carlos (Elsevier, 2020)

  The incidence of anterior cruciate ligament (ACL) lesions with Tanner stage ≤4 has been increasing in children. To stabilize the knee, different surgical techniques have been developed for ACL reconstruction in the pediatric ...
• Ventromedial and dorsolateral prefrontal interactions underlie will to fight and die for a cause

  Pretus, Clara; Hamid, Nafees; Sheikh, Hammad; Gómez, Angel; Ginges, Jeremy; Tobeña, Adolf; Davis, Richard; Vilarroya, Óscar; Atran, Scott (Oxford University Press, 2019)

  Willingness to fight and die (WFD) has been developed as a measure to capture willingness to incur costly sacrifices for the sake of a greater cause in the context of entrenched conflict. WFD measures have been repeatedly ...
• Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study

  Bleijenberg, Arne G.C.; Bessa Caserras, Xavier; Dekker, Evelien (BMJ Publishing Group, 2020)

  Background and aims: Serrated polyposis syndrome (SPS) is associated with an increased risk of colorectal cancer (CRC). International guidelines recommend surveillance intervals of 1-2 years. However, yearly surveillance ...
• Ellagic tcid as a Tool to limit the diabetes burden: updated evidence

  Amor, Antonio J.; Gómez-Guerrero, Carmen; Ortega, Emilio; Sala Vila, Aleix; Lázaro, Iolanda (MDPI, 2020)

  Oxidative stress contributes not only to the pathogenesis of type 2 diabetes (T2D) but also to diabetic vascular complications. It follows that antioxidants might contribute to limiting the diabetes burden. In this review ...
• Finding the dose for ceftolozane-tazobactam in critically ill children with and without acute kidney injury

  Butragueño-Laiseca, Laura; Troconiz, Iñaki F.; Grau Cerrato, Santiago; Campillo Ambrós, Núria; García, Xandra; Padilla, Belén; Fernández, Sarah N.; Santiago, María José (MDPI, 2020)

  Background: Ceftolozane-tazobactam is a new antibiotic against multidrug-resistant pathogens such as Pseudomonas aeruginosas. Ceftolozane-tazobactam dosage is still uncertain in children, especially in those with renal ...
• Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases

  Bousquet, Jean; Torre Fornell, Rafael de la; Pizarro Lozano, Mª Nieves; Antó i Boqué, Josep Maria (Elsevier, 2020)

  COVID-19 is described in a clinical case involving a patient who proposed the hypothesis that Nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-interacting nutrients may help to prevent severe COVID-19 symptoms. Capsules ...
• Mental health impact of the first wave of COVID-19 pandemic on Spanish healthcare workers: A large cross-sectional survey

  Alonso Caballero, Jordi; Vilagut Saiz, Gemma, 1975-; Mortier, Philippe; Ferrer, Montserrat; Alayo, Itxaso; Sanz, Ferran; Serra, Consol; MINDCOVID Working group (Elsevier, 2020)

  Introduction: Healthcare workers are vulnerable to adverse mental health impacts of the COVID-19 pandemic. We assessed prevalence of mental disorders and associated factors during the first wave of the pandemic among ...
• Uncovering de novo gene birth in yeast using deep transcriptomics

  Blevins, William Robert, 1987-; Ruiz Orera, Jorge, 1988-; Messeguer, Xavier; Blasco Moreno, Bernat, 1986-; Villanueva Cañas, José Luis, 1984-; Espinar, Lorena; Díez Antón, Juana, 1962-; Carey, Lucas, 1980-; Albà Soler, Mar (Nature Research, 2021)

  De novo gene origination has been recently established as an important mechanism for the formation of new genes. In organisms with a large genome, intergenic and intronic regions provide plenty of raw material for new ...
• The OMEGA-NET international inventory of occupational Cohorts

  Kogevinas, Manolis; Schlünssen, Vivi; Mehlum, Ingrid Sivesind; Turner, Michelle C. (Oxford University Press, 2020)

  In a recent count of cohort studies in Europe capturing information on occupation and/or occupational exposures, we estimated that there are more than 60 major studies with some type of occupational information that enrolled ...
• COVID-19 y África: sobreviviendo entre la espada y la pared

  Aranzabal, Maite de; Fumadó, Victoria; Alegria Coll, Iñaki; Rivera, Mercedes; Torre, Nuria; Guibert, Belen; Muñoz, María José; Moraleda, Cinta; Bassat, Quique; Grupo de Cooperación internacional de la Asociación Española de Pediatría (AEP) (Elsevier, 2020)

  Con más de 575.000 muertes y cerca de 13,3 millones de casos a nivel global, la pandemia por COVID-19 ha causado un terrible impacto en apenas medio año de evolución desde que por primera vez fuesen detectados casos en ...
• Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia

  Newland, Adrian C.; Sánchez González, Blanca; Rejtő, László; Egyed, Miklos; Romanyuk, Nataliya; Godar, Marie; Verschueren, Katrien; Gandini, Domenica; Ulrichts, Peter; Beauchamp, Jon; Dreier, Torsten; Ward, E. Sally; Michel, Marc; Liebman, Howard A.; de Haard, Hans; Leupin, Nicolas; Kuter, David J. (Wiley-Blackwell, 2020)

  Primary immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder, characterized by a low platelet count (<100 × 109 /L) in the absence of other causes associated with thrombocytopenia. In most patients, ...
• Evaluation of computationally designed peptides against TWEAK, a cytokine of the tumour necrosis factor ligand family

  Badia Villanueva, Miriam; Defaus, Sira; Foj, Ruben; Andreu Martínez, David; Oliva Miguel, Baldomero; Sierra, Angels; Fernández Fuentes, Narcís (MDPI, 2021)

  The tumour necrosis factor-like weak inducer of apoptosis (TWEAK) is a member of the tumour necrosis factor ligand family and has been shown to be overexpressed in tumoral cells together with the fibroblast growth ...
• COVID-19 incidence in patients with immunomediated inflammatory diseases: influence of immunosuppressant treatments

  Soldevila-Domenech, Natalia; Tío, Laura; Llorente Onaindia, Jone; Martín García, Elena, 1975-; Nebot Forcada, Pau; Torre Fornell, Rafael de la; Gurt, Alba; Maldonado, Rafael, 1961-; Monfort, Jordi; Covidmar Study Group (Frontiers, 2020)

  The effect of immunosuppressant treatments on the incidence of coronavirus disease (COVID-19) remains largely unknown. We studied the association between the pre-exposure to disease-modifying antirheumatic drugs (DMARDs) ...

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