• Methodological issues in a prospective study on plasma concentrations of persistent organic pollutants and pancreatic cancer risk within the EPIC cohort

  Gasull Panadès, Magda; Pumarega Rodríguez, José Antonio; Iglesias Coma, Mar; Kühn, Tilman; Porta Serra, Miquel (Elsevier, 2019)

  BACKGROUND: The use of biomarkers of environmental exposure to explore new risk factors for pancreatic cancer presents clinical, logistic, and methodological challenges that are also relevant in research on other complex ...
• Traffic-related air pollution, APOEε4 status, and neurodevelopmental outcomes among school children enrolled in the BREATHE project (Catalonia, Spain)

  Alemany, Silvia; Vilor Tejedor, Natàlia, 1988-; García Esteban, Raquel; Bustamante Pineda, Mariona; Dadvand, Payam; Esnaola, Mikel; Mortamais, Marion; Forns i Guzman, Joan, 1981-; van Drooge, Barend L.; Álvarez Pedrerol, Mar; Grimalt Obrador, Joan; Rivas, Ioar; Querol, Xavier; Pujol Martí, Jesús, 1981-; Sunyer Deu, Jordi (National Institute of Environmental Health Sciences (NIEHS), 2018)

  BACKGROUND: Traffic-related air pollution is emerging as a risk factor for Alzheimer's disease (AD) and impaired brain development. Individual differences in vulnerability to air pollution may involve the ε4 allele of ...
• Evaluation of the impact of ambient temperatures on occupational injuries in Spain

  Martínez Solanas, Èrica, 1982-; López Ruiz, María, 1982-; Wellenius, Gregory A.; Gasparrini, Antoni; Sunyer Deu, Jordi; Benavides, Fernando G.(Fernando García); Basagaña Flores, Xavier (National Institute of Environmental Health Sciences (NIEHS), 2018)

  BACKGROUND: Extreme cold and heat have been linked to an increased risk of occupational injuries. However, the evidence is still limited to a small number of studies of people with relatively few injuries and with a limited ...
• Evaluating the association between artificial light-at-night exposure and breast and prostate cancer risk in Spain (MCC-Spain study).

  Garcia-Saenz, Ariadna; Espinosa Díaz, Ana; Valentín, Antònia; Castaño Vinyals, Gemma; Kogevinas, Manolis (National Institute of Environmental Health Sciences (NIEHS), 2018)

  BACKGROUND: Night shift work, exposure to light at night (ALAN) and circadian disruption may increase the risk of hormone-dependent cancers. OBJECTIVES: We evaluated the association of exposure to ALAN during sleeping time ...
• Common variants at 12q15 and 12q24 are associated with infant head circumference

  Taal, H. Rob; Guxens Junyent, Mònica; Sunyer Deu, Jordi; Estivill, Xavier, 1955-; Jaddoe, Vincent W. V. (Nature Research, 2012)

  To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy ...
• Microorganisms resistant to conventional antimicrobials in acute exacerbations of chronic obstructive pulmonary disease

  Estirado Vera, Cristina; Ceccato, Adrian; Guerrero, Monica; Huerta, Arturo; Cilloniz, Catia; Vilaró, Olivia; Gabarrús, Albert; Gea Guiral, Joaquim; Crisafulli, Ernesto; Soler, Nestor; Torres, Antoni (BioMed Central, 2018)

  Background: Antimicrobial treatment for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) remains controversial. In some cases AECOPD are caused by microorganisms that are resistant to treatments ...
• Alkylphenolic compounds and risk of breast and prostate cancer in the MCC-Spain study

  Peremiquel-Trillas, Paula; Tusquets Trias de Bes, Ignacio; Castaño Vinyals, Gemma; Kogevinas, Manolis; Costas, Laura (Elsevier, 2019)

  BACKGROUND: Alkylphenolic compounds are chemicals with endocrine disrupting properties that have been widely used in industry with important changes in their usage over time. Few epidemiologic studies have evaluated the ...
• Green and blue spaces and physical functioning in older adults: Longitudinal analyses of the Whitehall II study

  de Keijzer, Carmen; Tonne, Cathryn; Sabia, Severine; Basagaña Flores, Xavier; Valentín, Antònia; Singh-Manoux, Archana; Antó i Boqué, Josep Maria; Alonso Caballero, Jordi; Nieuwenhuijsen, Mark J.; Sunyer Deu, Jordi; Dadvand, Payam (Elsevier, 2019)

  There is increasing evidence of the health benefits of exposure to natural environments, including green and blue spaces. The association with physical functioning and its decline at older age remains to be explored. The ...
• Weather and gastrointestinal disease in Spain: A retrospective time series regression study

  Morral, Clara; Martínez Solanas, Èrica, 1982-; Villanueva Belmonte, Cristina; Basagaña Flores, Xavier (Elsevier, 2018)

  BACKGROUND: A few studies in high-income countries have investigated the relationship between ambient temperature and/or precipitation and the occurrence of gastroenteritis. In most of the cases, hot temperatures and heavy ...
• Circulating miR-103a-3p and miR-660-5p are associated with bone parameters in patients with controlled acromegaly

  Valassi, Elena; García-Giralt, Natalia; Malouf Sierra, Jorge; Crespo, Iris; Llauger, Jaume; Diez Pérez, Adolfo; Webb, Susan M. (BioScientifica, 2019)

  Background Biochemical control of GH/IGF-I excess in acromegaly (ACRO) is associated with persistent impairment of trabecular microstructure leading to increased risk of vertebral fractures. Circulating miRNAs modulate the ...
• Whole blood storage in CPDA1 blood bags alters erythrocyte membrane proteome

  Al-Thani, Amna Mohamed; Voss, Sven Christian; Al-Menhali, Afnan Saleh; Barcaru, Andrei; Horvatovich, Peter; Al Jaber, Hind; Nikolovski, Zoran; Latiff, Aishah; Georgakopoulos, Costas; Merenkov, Zeyd; Segura Noguera, Jordi; Alsayrafi, Mohammed; Jaganjac, Morana (Hindawi, 2018)

  Autologous blood transfusion (ABT) has been frequently abused in endurance sport and is prohibited since the mid-1980s by the International Olympic Committee. Apart from any significant performance-enhancing effects, the ...
• Response to growth hormone in patients with RNPC3 mutations

  Martos Moreno, Gabriel A.; Travieso-Suárez, Lourdes; Pozo-Román, Jesús; Muñoz-Calvo, María T.; Chowen, Julie A.; Frilander, Mikko J.; Pérez Jurado, Luis Alberto; Hawkins, Federico G.; Argente, Jesús (Wiley-Blackwell, 2018)
• Endovascular treatment of thoracic aortic pseudoaneurysm through a subclavian approach in patient with aortoiliac occlusive disease: a case report

  Paredes-Mariñas, Ezequiel; Llort-Pont, Carme; Castro-Bolance, Francisca; Riambau-Alonso, Vicente (Elsevier, 2018)

  INTRODUCTION: Thoracic endovascular aortic repair (TEVAR) has become the preferred option for treatment of thoracic aortic pathology, but lack of vascular access options is a common contraindication to TEVAR. CASE REPORT: ...
• Deletion of Maged1 in mice abolishes locomotor and reinforcing effects of cocaine

  De Backer, Jean-François; Monlezun, Stéphanie; Detraux, Bérangère; Gazan, Adeline; Vanopdenbosch, Laura; Cheron, Julian; Cannazza, Giuseppe; Valverde, Sébastien; Cantacorps, Lídia; Nassar, Mérie; Venance, Laurent; Valverde Granados, Olga; Faure, Philippe; Zoli, Michele; De Backer, Olivier; Gall, David; Schiffmann, Serge N.; de Kerchove d'Exaerde, Alban (Wiley-Blackwell, 2018)

  Melanoma antigen genes (Mage) were first described as tumour markers. However, some of Mage are also expressed in healthy cells where their functions remain poorly understood. Here, we describe an unexpected role for one ...
• Endothelial cell activation on 3D-matrices derived from PDGF-BB-stimulated fibroblasts is mediated by Snail1

  Herrera, Alberto; Herrera, Mercedes; Guerra-Perez, Natalia; Galindo-Pumariño, Cristina; Larriba, María Jesús; García-Barberán, Vanesa; Gil, Beatriz; Giménez-Moyano, Sara; Ferreiro-Monteagudo, Reyes; Veguillas, Pilar; Candia, Antonio; Peña, Raúl; Pinto, Jesús; García-Bermejo, Mª Laura; Muñoz, Alberto; García de Herreros, Antonio; Bonilla, Félix; Carrato, Alfredo; Peña, Cristina (Nature Research, 2018)

  Carcinomas, such as colon cancer, initiate their invasion by rescuing the innate plasticity of both epithelial cells and stromal cells. Although Snail is a transcriptional factor involved in the Epithelial-Mesenchymal ...
• Specific IgE and IgG measured by the MeDALL allergen-chip depend on allergen and route of exposure: The EGEA study

  Siroux, Valérie; Lupinek, Christian; Resch, Yvonne; Curin, Mirela; Just, Jocelyne; Keil, Thomas; Kiss, Renata; Lodrup Carlsen, Karin C.; Melén, Erik; Nadif, Rachel; Pin, Isabelle; Skrindo, Ingebjorg; Vrtala, Susanne; Wickman, Magnus; Antó i Boqué, Josep Maria; Valenta, Rudolf; Bousquet, Jean (Elsevier, 2017)

  Background: The nature of allergens and route and dose of exposure may affect the natural development of IgE and IgG responses. Objective: We sought to investigate the natural IgE and IgG responses toward a large panel of ...
• Wine and olive oil phenolic compounds interaction in humans

  Boronat Rigol, Anna; Martínez-Huélamo, Miriam; Cobos, Ariadna; Torre Fornell, Rafael de la (MDPI, 2018)

  Extra virgin olive oil (EVOO) and red wine (RW) are two basic elements that form part of the so-called Mediterranean diet. Both stand out because of their high phenolic compound content and their potential related health ...
• COSMIC project: consensus on the objectives of the metabolic syndrome in clinic

  Pedro-Botet, Juan Carlos; Ascaso Gimilio, Juan Francisco; Barrios Alonso, Vivencio; Sierra, Alejandro de la; Escalada, Javier; Millán Núñez-Cortés, Jesús; Mostaza, José María; Pérez-Martínez, Pablo; Pintó Sala, Xavier; Salas-Salvadó, Jordi; Valdivielso, Pedro (Dove Medical Pres, 2018)

  Metabolic syndrome (MetS), a disorder with a high and growing prevalence, is a recognized risk factor for cardiovascular disease (CVD) and type 2 diabetes. It is a constellation of clinical and metabolic risk factors that ...
• DNA sequence variation in ACVR1C encoding the activin receptor-like kinase 7 influences body fat distribution and protects against type 2 diabetes

  Emdin, Connor A.; Elosua Llanos, Roberto; Kathiresan, Sekar (American Diabetes Association, 2019)

  A genetic predisposition to higher waist-to-hip ratio adjusted for BMI (WHRadjBMI), a measure of body fat distribution, associates with increased risk for type 2 diabetes. We conducted an exome-wide association study of ...
• The effect of tea consumption on the steroid profile

  Coll, Sergi; Matabosch Geronès, Xavier; Garrostas, Lorena; Monfort Mercader, Núria, 1983-; Perez-Maña, Clara; Pizarro Lozano, Mª Nieves; Mateus Rodriguez, Julian Andrés; Ezzel, Mohammed; Torre Fornell, Rafael de la; Ventura Alemany, Rosa (Wiley, 2018)

  Green tea (GT), along with its flavonol epigallocatechin-3-gallate (EGCG), has shown to inhibit the UGT2B17 isoenzyme, which is highly involved in the glucuronidation of testosterone (T) and its metabolites. Since the ...

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