• Association analyses identify 31 new risk loci for colorectal cancer susceptibility

  Law, Philip J.; The PRACTICAL consortium; Dunlop, Malcolm G. (Nature Research, 2019)

  Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide, and has a strong heritable basis. We report a genome-wide association analysis of 34,627 CRC cases and 71,379 controls of European ancestry that ...
• Use of health apps by nurses for professional purposes: web-based survey study

  Mayer, Miguel Ángel, 1960-; Rodríguez Blanco, Octavi; Torrejon, Antonio (JMIR Publications Inc., 2019)

  Background: In the last few years, the number of mobile apps for health professionals has increased exponentially. Nevertheless, there is a lack of knowledge about the professional use, training requirements, and quality ...
• Adaptación transcultural del cuestionario Mastocytosis Quality of Life questionnaire (MC-QoL) del alemán al castellano

  Bertolín Colilla, M.; Garín, O.; Siebenhaar, F.; Maurer, Marcus; Pujol Vallverdú, Ramon Maria; Giménez Arnau, Anna Maria (Elsevier, 2020)

  Introducción: Las mastocitosis son un grupo de proliferaciones clonales de mastocitos que pueden afectar a distintos órganos y tejidos, siendo la piel uno de los implicados con mayor frecuencia. La clínica está relacionada ...
• Beer phenolic composition of simple phenols, prenylated flavonoids and alkylresorcinols

  Boronat Rigol, Anna, 1990-; Soldevila-Domenech, Natalia; Rodríguez-Morató, Jose, 1987-; Martínez-Huélamo, Miriam; Lamuela-Raventós, Rosa M.; Torre Fornell, Rafael de la (MDPI, 2020)

  Beer is a fermented beverage with beneficial phenolic compounds and is widely consumed worldwide. The current study aimed to describe the content of three families of phenolic compounds with relevant biological activities: ...
• Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans

  Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra Albà, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)

  Here we present new and original data on the endogenous conversion of tyrosol (Tyr) into hydroxytyrosol (OHTyr) in humans and its effects on the cardiovascular system. A randomized, crossover, controlled clinical trial was ...
• Comparison of autofluorescence and white-light bronchoscopies performed with the Evis Lucera Spectrum for the detection of bronchial cancers: a meta-analysis

  Sun, Shuangshuang; Yang, Yang; Chen, Meizi; Wang, Li; Pan, Hangcheng; Zhang, Xiuwei; Wagnieres, Georges; Mohammad, Yousser; Barreiro Portela, Esther; Pirozzolo, Giovanni; Villeneuve, P. James; Zhan, Ping; Wan, Bing; AME Lung Cancer Collaborative Group (Pioneer Bioscience Publishing Company, 2020)

  Background: Many recent studies have reported that autofluorescence bronchoscopy (AFB) has a superior sensitivity and decreased specificity in the diagnosis of bronchial cancers when compared with white-light bronchoscopy ...
• Thromboembolic, cardiovascular and overall mortality risks of aromatase inhibitors, compared with tamoxifen treatment: an outpatient-register-based retrospective cohort study

  Pineda-Moncusí, Marta; Garcia Giralt, Natàlia; Díez Pérez, Adolfo; Tusquets Trias de Bes, Ignacio; Servitja Tormo, Sonia; Albanell Mestres, Joan; Prieto-Alhambra, Daniel; Nogués Solan, Francesc Xavier (SAGE Publications, 2020)

  Background: Tamoxifen (TAM) and aromatase inhibitor (AI) therapies have been associated with increased risk of thromboembolic and cardiovascular events, respectively, in addition to other side effects. This study analysed ...
• Gestational diabetes impacts fetal precursor cell responses with potential consequences for offspring

  Algaba-Chueca, Francisco; Maymó-Masip, M.Elsa; Ejarque, Miriam; Ballesteros, Mónica; Llauradó Cabot, Gemma; López, Carlos; Guarque, Albert; Serena, Carolina; Martínez-Guasch, Laia; Gutiérrez, Cristina; Bosch, Ramón; Vendrell, Joan; Megia, Ana; Fernández Veledo, Sonia (Wiley, 2020)

  Fetal programming has been proposed as a key mechanism underlying the association between intrauterine exposure to maternal diabetes and negative health outcomes in offspring. To determine whether gestational diabetes ...
• MMP-10 is increased in early stage diabetic kidney disease and can be reduced by renin-angiotensin system blockade

  Mora-Gutiérrez, José María; Rodríguez, José Antonio; Fernández-Seara, María A.; Orbe, Josune; Escalada, Francisco Javier; Soler, María José; Slon Roblero, María Fernanda; Riera Oliva, Marta; Páramo, José Antonio; García-Fernández, Nuria (Nature Research, 2020)

  Matrix metalloproteinases have been implicated in diabetic microvascular complications. However, little is known about the pathophysiological links between MMP-10 and the renin-angiotensin system (RAS) in diabetic kidney ...
• Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study

  Rojo-Martínez, Gemma; Goday Arno, Alberto; Calle-Pascual, Alfonso (Nature Research, 2020)

  Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population. In total 5072 people older than 18 years,were ...
• Creating urban green infrastructure where it is needed - A spatial ecosystem service-based decision analysis of green roofs in Barcelona

  Langemeyer, Johannes; Wedgwood, Diego; McPhearson, Timon; Baró Porras, Francesc; Madsen, Anders L.; Barton, David N. (Elsevier, 2020)

  As cities face increasing pressure from densification trends, green roofs represent a valuable source of ecosystem services for residents of compact metropolises where available green space is scarce. However, to date ...
• Reduced airway levels of fatty-acid binding protein 4 in COPD: relationship with airway infection and disease severity

  Perea, Lídia; Rodrigo-Troyano, Ana; Cantó, Elisabet; Domínguez-Álvarez, Marisol; Giner, Jordi; Sanchez-Reus, Ferran; Villar García, Judit; Quero, Sara; García-Nuñez, Marian; Marín, Alicia; Monsó, Eduard; Faner, Rosa; García-Nuñez, Marian; Vidal, Silvia; Sibila, Oriol (BioMed Central, 2020)

  Background: For still unclear reasons, chronic airway infection often occurs in patients with Chronic Obstructive Pulmonary Disease (COPD), particularly in those with more severe airflow limitation. Fatty-acid binding ...
• Becoming a mother entails anatomical changes in the ventral striatum of the human brain that facilitate its responsiveness to offspring cues

  Hoekzema, Elseline; Tamnes, Christian K.; Berns, Puck; Barba-Müller, Erika; Pozzobon, Cristina; Picado, Marisol; Lucco, Florencio; Martínez-García, Magdalena; Desco, Manuel; Ballesteros, Agustín; Crone, Eveline A.; Vilarroya, Óscar; Carmona, Susanna (Elsevier, 2020)

  In mothers, offspring cues are associated with a powerful reinforcing value that motivates maternal care. Animal studies show that this is mediated by dopamine release into the nucleus accumbens, a core component of the ...
• Psychoeducation for bipolar disorder and risk of recurrence and hospitalization - a within-individual analysis using registry data

  Joas, Erik; Bäckman, Kristoffer; Karanti, Alina; Sparding, Timea; Colom, Francesc; Pålsson, Erik; Landén, Mikael (Cambridge University Press, 2020)

  Background: The efficacy of psychoeducation for bipolar disorder has been demonstrated in clinical trials, but it is not known if the results translate into effectiveness in routine clinical practice. The aim was to determine ...
• Surface respiratory electromyography and dyspnea in acute heart failure patients

  Luiso, Daniele; Villanueva, Jair A.; Belarte-Torner, Laia C.; Fort, Aleix; Blázquez-Bermejo, Zorba; Ruiz, Sonia; Farré, Ramon; Rigau, Jordi; Martí Almor, Julio; Farré López, Núria (Public Library of Science (PLoS), 2020)

  Introduction and objectives: Dyspnea is the most common symptom among hospitalized patients with heart failure (HF) but besides dyspnea questionnaires (which reflect the subjective patient sensation and are not fully ...
• ReorientExpress: reference-free orientation of nanopore cDNA reads with deep learning

  Ruiz Reche, Angel; Srivastava, Akanksha; Indi, Joel A.; de la Rubia, Ivan; Eyras Jiménez, Eduardo (BioMed Central, 2019)

  We describe ReorientExpress, a method to perform reference-free orientation of transcriptomic long sequencing reads. ReorientExpress uses deep learning to correctly predict the orientation of the majority of reads, and in ...
• Longitudinal association of changes in diet with changes in body weight and waist circumference in subjects at high cardiovascular risk: the PREDIMED trial

  Konieczna, Jadwiga; Romaguera Bosch, Dora; Pereira, Verónica; Fiol, Miquel; Razquin, Cristina; Estruch, Ramón; Asensio, Eva M.; Babio, Nancy; Fitó Colomer, Montserrat; Gómez Gracia, Enrique; Ros, Emilio; Lapetra, José; Arós, Fernando; Serra Majem, Lluís; Pintó Sala, Xavier; Toledo, Estefania; Sorlí, José V.; Bulló, Mònica; Schröder, Helmut, 1958-; Martínez-González, Miguel A. (BioMed Central, 2019)

  Background: Consumption of certain foods is associated with long-term weight gains and abdominal fat accumulation in healthy, middle-aged and young, non-obese participants. Whether the same foods might be associated with ...
• Hydroxychloroquine and Chloroquine for treatment of SARS-CoV-2 (COVID-19)

  Pastick, Katelyn A.; Okafor, Elizabeth C.; Wang, Fan; Lofgren, Sarah M.; Skipper, Caleb P.; Nicol, Melanie R.; Pullen, Matthew F.; Rajasingham, Radha; McDonald, Emily G.; Lee, Todd C.; Schwartz, Ilan S.; Kelly, Lauren E.; Lother, Sylvain A.; Mitjà, Oriol; Letang Jiménez de Anta, Emilio Ángel; Abassi, Mahsa; Boulware, David R. (Oxford University Press, 2020)

  Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly emerging viral infection causing coronavirus disease 2019 (COVID-19). Hydroxychloroquine and chloroquine have garnered unprecedented attention as ...
• A phase 3 study to compare delafloxacin with moxifloxacin for the treatment of adults with community-acquired bacterial pneumonia (DEFINE-CABP)

  Horcajada Gallego, Juan Pablo; Salata, Robert A.; Álvarez-Sala, Rodolfo; Nitu, Floarea Mimi; Lawrence, Laura; Quintas, Megan; Cheng, Chun-Yen; Cammarata, Sue; DEFINE-CABP Study Group (Oxford University Press, 2020)

  Background: The clinical and economic burden of community-acquired bacterial pneumonia (CABP) is significant and is anticipated to increase as the population ages and pathogens become more resistant. Delafloxacin is a ...
• Associations of sickness absence for pain in the low back, neck and shoulders with wider propensity to pain

  Coggon, David; Serra, Consol; Harcombe, Helen (BMJ Publishing Group, 2020)

  Objectives: To explore the association of sickness absence ascribed to pain at specific anatomical sites with wider propensity to musculoskeletal pain. Methods: As part of the CUPID (Cultural and Psychosocial Influences ...

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