• Accelerated redevelopment of vocal skills is preceded by lasting reorganization of the song motor circuitry

  Vellema, Michiel; Diales Rocha, Mariana; Bascones, Sabrina; Zsebők, Sándor; Dreier, Jes; Leitner, Stefan; Van der Linden, Annemie; Brewer, Jonathan; Gahr, Manfred (eLife, 2019)

  Complex motor skills take considerable time and practice to learn. Without continued practice the level of skill performance quickly degrades, posing a problem for the timely utilization of skilled motor behaviors. Here ...
• Meniscal allograft transplants and new scaffolding techniques

  Pereira, Hélder; Fatih Cengiz, Ibrahim; Gomes, Sérgio; Espregueira-Mendes, João; Ripoll, Pedro L.; Monllau García, Juan Carlos; Reis, Rui L.; Oliveira, J. Miguel (British Editorial Society of Bone & Joint Surgery, 2019)

  Clinical management of meniscal injuries has changed radically in recent years. We have moved from the model of systematic tissue removal (meniscectomy) to understanding the need to preserve the tissue.Based on the increased ...
• Association of first-trimester HbA1c levels with adverse pregnancy outcomes in different ethnic groups

  Mañé, Laura; Flores-Le-Roux, Juana Antonia; Gómez, Nàdia; Chillarón Jordan, Juan José; Llauradó Cabot, Gemma; Gortazar, Lucía; Payà Panadés, Antonio; Pedro-Botet, Juan Carlos; Benaiges Foix, David (Elsevier, 2019)

  Aim: To determine, in a multi-ethnic cohort, the association of first-trimester HbA1c levels with the development of pregnancy complications. Methods: A prospective study between April 2013-October 2016. Participants were ...
• The evolving biomarker landscape for treatment selection in metastatic colorectal cancer

  Taieb, Julien; Jung, Andreas; Sartore Bianch, Andrea; Peeters, Marc; Seligmann, Jenny; Zaanan, Aziz; Burdon, Peter; Montagut Viladot, Clara; Laurent Puig, Pierre (SpringerOpen, 2019)

  The approval of targeted therapies for metastatic colorectal cancer (mCRC) has led to important improvements in patient outcomes. However, it is still necessary to increase individualisation of treatments based on tumour ...
• Prevalence of postprandial hyperglycaemia in basal insulin-treated patients with type 2 diabetes mellitus with controlled fasting glycaemia and elevated glycosylated haemoglobin

  Tinahones Madueño, Francisco José; Molina Vega, María; Parra Barona, Juan; Flores-Le-Roux, Juana Antonia; Gómez Huelga, Ricardo (BioMed Central, 2019)

  Objective: To study the prevalence of postprandial hyperglycaemia (PPH) in type 2 diabetes mellitus (T2DM) patients treated with basal insulin, having fasting glucose < 130 mg/dL but HbA1c > 7.0% (53 mmol/mol). Methods: ...
• Effects of a mediterranean eating plan on the need for glucose-lowering medications in participants with type 2 diabetes: a subgroup analysis of the PREDIMED trial

  Basterra-Gortari, F. Javier; Ruiz-Canela, Miguel; Martinez-Gonzalez, Miguel A.; Babio, Nancy; Sorlí, J.V.; Fitó Colomer, Montserrat; Ros, Emilio; Gómez-Gracia, Enrique; Fiol, Miquel; Lapetra, José; Estruch, Ramón; Serra-Majem, Luis; Pinto, Xavier; González, José I.; Bulló, Mònica; Castañer, Olga; Alonso-Gómez, A.; Forga, Luis; Arós, Fernando; PREDIMED investigators (American Diabetes Association, 2019)

  OBJECTIVE: To examine the effects of two Mediterranean eating plans (Med-EatPlans) versus a low-fat eating plan on the need for glucose-lowering medications. RESEARCH DESIGN AND METHODS: From the Prevención con Dieta ...
• Plasma lipidomic profiling and risk of type 2 diabetes in the PREDIMED trial

  Razquin, Cristina; Fitó Colomer, Montserrat; Martinez-Gonzalez, Miguel A. (American Diabetes Association, 2018)

  OBJECTIVE: Specific lipid molecular changes leading to type 2 diabetes (T2D) are largely unknown. We assessed lipidome factors associated with future occurrence of T2D in a population at high cardiovascular risk. RESEARCH ...
• Neurodevelopmental correlates of the emerging adult self

  Davey, Christopher G.; Fornito, Alex; Pujol Nuez, Jesús; Breakspear, Michael; Schmaal, Lianne; Harrison, Ben J. (Elsevier, 2019)

  The self-concept - the set of beliefs that a person has about themselves - shows significant development from adolescence to early adulthood, in parallel with brain development over the same period. We sought to investigate ...
• Red and Orange Colors as Dermoscopic Clues for Fish-Tank Granuloma

  Lobato-Berezo, Alejandro; Martín-Ezquerra, Gemma; Vidal-Navarro, Ainhoa; Pujol Vallverdú, Ramon Maria (Derm101, 2019)
• Gender commonalities and differences in risk and protective factors of suicidal thoughts and behaviors: A cross-sectional study of Spanish university students

  Miranda-Mendizábal, Andrea; Torrent, Aina; Mortier, Philippe; Alonso Caballero, Jordi (Wiley, 2019)

  AIM: To assess gender differences in the association between risk/protective factors and suicidal thoughts and behaviors (STB); and whether there is any gender-interaction with those factors and STB; among Spanish university ...
• ResMarkerDB: a database of biomarkers of response to antibody therapy in breast and colorectal cancer

  Pérez-Granado, Judith; Piñero González, Janet, 1977-; Furlong, Laura I., 1971- (Oxford University Press, 2019)

  The clinical efficacy of therapeutic monoclonal antibodies for breast and colorectal cancer has greatly contributed to the improvement of patients' outcomes by individualizing their treatments according to their genomic ...
• Data on a new biomarker for kidney transplant recipients: The number of FoxP3 regulatory T cells in the circulation

  Herrera-Gómez Francisco; del Aguila, Waldo; Tejero-Pedregosa, Armando; Adler, Marcel; Padilla-Berdugo, Rosario; Maurtua-Briseño-Meiggs, Álvaro; Pascual Santos, Julio; Pascual, Manuel; San Segundo, David; Heidt, Sebastiaan; Álvarez, F. Javier; Ochoa-Sangrador, Carlos; Lambert, Claude (Elsevier, 2018)

  This article presents unrevealed details of the systematic review process of the article "The number of FoxP3 regulatory T cells in the circulation may be a predictive biomarker for kidney transplant recipients: A multistage ...
• Comparative efficacy of linezolid and vancomycin for endotracheal tube MRSA biofilms from ICU patients

  Fernández-Barat, Laia; Motos, Ana; Panigada, Mauro; Álvarez Lerma, Francisco; Viña, Lucía; Lopez-Aladid, Ruben; Ceccato, Adrian; Bassi, Gianluigi Li; Nicolau, David P.; Lopez, Yuli; Muñoz, Laura; Guerrero, Laura; Soy, Dolors; Israel, Trinidad; Castro, Pedro; Torres, Antoni (BioMed Central, 2019)

  PURPOSE: To compare the efficacy of systemic treatment with linezolid (LNZ) versus vancomycin (VAN) on methicillin-resistant Staphylococcus aureus (MRSA) burden and eradication in endotracheal tube (ETT) biofilm and ETT ...
• European surveillance system on contact allergies (ESSCA): contact allergies in relation to body sites in patients with allergic contact dermatitis

  Oosterhaven, Jart A.F.; Uter, Wolfgang; Aberer, Werner; Armario-Hita, José C.; Ballmer-Weber, Barbara K.; Bauer, Andrea; Czarnecka-Operacz, Magdalena; Elsner, Peter; García-Gavín, Juan; Giménez Arnau, Anna Maria; John, Swen M.; Kręcisz, Beata; Mahler, Vera; Rustemeyer, Thomas; Sadowska-Przytocka, Anna; Sánchez-Pérez, Javier; Dagmar Simon; Valiukevicienė, Skaidra; Weisshaar, Elke; Schuttelaar, Marie L. A.; ESSCA Working Group (Wiley, 2019)

  BACKGROUND: Analyses of the European Surveillance System on Contact Allergies (ESSCA) database have focused primarily on the prevalence of contact allergies to the European baseline series, both overall and in subgroups ...
• Ranking of stroke and cardiovascular risk factors for an optimal risk calculator design: Logistic regression approach

  Cuadrado Godia, Elisa; Jamthikar, Ankush D.; Khanna, Narendra N.; Araki, Tadashi; Maniruzzaman, M.; Saba, Luca; Nicolaides, Andrew; Sharma, Aditya; Omerzu, Tomaz; Suri, Harman S.; Gupta, Ajay V.; Mavrogeni, Sophie; Turk, Monika; Laird, John R.; Protogerou, Athanasios; Sfikakis, Petros; Kitas, George D.; Viswanathan, Vijay; Sur, Jasjit S. (Elsevier, 2019)

  PURPOSE: Conventional cardiovascular risk factors (CCVRFs) and carotid ultrasound image-based phenotypes (CUSIP) are independently associated with long-term risk of cardiovascular (CV) disease. In this study, 26 cardiovascular ...
• Dose-response pharmacological study of mephedrone and its metabolites: pharmacokinetics, serotoninergic effects, and impact of CYP2D6 genetic variation

  Olesti Muñoz, Eulàlia; Farré Albaladejo, Magí; Carbó Banús, Marcel·lí; Papaseit Fontanet, Esther; Pérez Mañá, Clara; Torrens, Marta; Yubero Lahoz, Samanta, 1985-; Pujadas Bastardes, Mitona; Pozo Mendoza, Óscar J., 1975-; Torre Fornell, Rafael de la (Wiley, 2019)

  Mephedrone (MEPH), the most widely consumed synthetic cathinone, has been associated with acute toxicity episodes. The aim of this report was to study its metabolic disposition and the impact of genetic variation of CYP2D6 ...
• Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

  Bousquet, Jean; Antó i Boqué, Josep Maria; Wallace, D.V.; The MASK study group (BioMed Central, 2019)

  AIMS: Mobile Airways Sentinel NetworK (MASK) belongs to the Fondation Partenariale MACVIA-LR of Montpellier, France and aims to provide an active and healthy life to rhinitis sufferers and to those with asthma multimorbidity ...
• Indicaciones de los inhibidores de PCSK9 en la práctica clínica. Recomendaciones de la Sociedad Española de Arteriosclerosis (SEA), 2019

  Ascaso Gimilio, Juan Francisco; Civeira, Fernando; Guijarro, Carlos; López Miranda, José; Masana, Luís; Mostaza, José María; Pedro-Botet, Juan Carlos; Pintó Sala, Xavier; Valdivielso, Pedro (Elsevier, 2019)

  A group of experts convened by the Spanish Society of Arteriosclerosis (SEA) has been in charge of updating the SEA document on the indications of PCSK9 inhibitors (PCSK9i) in clinical practice that was published in 2016. ...
• Subtype specificity of genetic loci associated with stroke in 16 664 cases and 32 792 controls

  Traylor, Matthew; Jiménez-Conde, Jordi; Malik, Rainer (Lippincott Williams & Wilkins, 2019)

  BACKGROUND: Genome-wide association studies have identified multiple loci associated with stroke. However, the specific stroke subtypes affected, and whether loci influence both ischemic and hemorrhagic stroke, remains ...
• Rare protein-truncating variants in APOB, lower low-density lipoprotein cholesterol, and protection against coronary heart disease

  Peloso, Gina M.; Marrugat de la Iglesia, Jaume; Kathiresa, Sekar (Lippincott Williams & Wilkins, 2019)

  Background Familial hypobetalipoproteinemia is a genetic disorder caused by rare protein-truncating variants (PTV) in the gene encoding APOB (apolipoprotein B), the major protein component of LDL (low-density lipoprotein) ...

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