Browsing Hospital del Mar Research Institute by Title

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  • MMP-10 is increased in early stage diabetic kidney disease and can be reduced by renin-angiotensin system blockade
    Mora-Gutiérrez, José María; Rodríguez, José Antonio; Fernández-Seara, María A.; Orbe, Josune; Escalada, Francisco Javier; Soler, María José; Slon Roblero, María Fernanda; Riera Oliva, Marta; Páramo, José Antonio; García-Fernández, Nuria (Nature Research, 2020)
    Matrix metalloproteinases have been implicated in diabetic microvascular complications. However, little is known about the pathophysiological links between MMP-10 and the renin-angiotensin system (RAS) in diabetic kidney ...
  • Modeling SARS-CoV-2 proteins in the CASP-commons experiment
    Kryshtafovych, Andriy; Moult, John; Billings, Wendy M.; Della Corte, Dennis; Fidelis, Krzysztof; Kwon, Sohee; Olechnovič, Kliment; Seok, Chaok; Venclovas, Česlovas; Won, Jonghun; CASP-COVID participants (Wiley, 2021)
    Critical Assessment of Structure Prediction (CASP) is an organization aimed at advancing the state of the art in computing protein structure from sequence. In the spring of 2020, CASP launched a community project to compute ...
  • Modeling the impact of neuromorphological alterations in Down syndrome on fast neural oscillations
    Clusella, Pau; Manubens-Gil, Linus, 1989-; García Ojalvo, Jordi; Dierssen, Mara (Public Library of Science (PLoS), 2024)
    Cognitive disorders, including Down syndrome (DS), present significant morphological alterations in neuron architectural complexity. However, the relationship between neuromorphological alterations and impaired brain ...
  • Modelos de prestación de asistencia sanitaria para la artrosis
    Castro Domínguez, Francisco; Melo, Luciano; Eyles, Jillian P. (Elsevier, 2018)
  • Models of disuse muscle atrophy: therapeutic implications in critically ill patients
    Barreiro Portela, Esther (AME Publishing Company, 2018)
    Skeletal muscle weakness is common in the intensive care units (ICU). Approximately 50% of patients under mechanical ventilation for more than 7 days show signs of ICU-acquired muscle weakness. In these patients, muscle ...
  • Moderate red wine consumption is associated with a lower prevalence of the metabolic syndrome in the PREDIMED population.
    Tresserra-Rimbau, Anna; Medina-Remón, Alexander; Lamuela-Raventós, Rosa M.; Bulló, Mònica; Salas-Salvadó, Jordi; Corella, Dolores; Fitó Colomer, Montserrat; Gea, Alfredo; Gómez-Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol, Miquel; Ros, Emilio; Serra-Majem, Luis; Pinto, Xavier; Muñoz, Miguel Ángel; Estruch, Ramón; PREDIMED investigators (Cambridge University Press, 2015)
    Previous studies on the association between alcohol intake and the development of the metabolic syndrome (MetS) have yielded inconsistent results. Besides, few studies have analysed the effects of red wine (RW) consumption ...
  • Moderate to severe psoriasis in pediatric and young patients: the BIOBADADERM registry experience
    Nieto Benito, L.M.; Ferran Farrés, Marta; García-Doval, Ignacio; Biobadaderm Study Group (Elsevier, 2022)
    Childhood-onset psoriasis generally follows an indolent course but patients with moderate or severe disease may require systemic treatment. The aim of this study was to determine the relative proportion of children and ...
  • Moderate wine consumption measured using the biomarker urinary tartaric acid concentration decreases inflammatory mediators related to atherosclerosis
    Domínguez López, Inés; Arancibia-Riveros, Camila; Casas, Rosa; Galkina, Polina; Pérez Bosch, Maria; Martínez-González, Miguel Ángel, 1957-; Fitó Colomer, Montserrat; Ros, Emilio; Estruch, Ramón; Lamuela-Raventós, Rosa M. (Elsevier, 2024)
    Objectives: Several studies suggest that moderate wine consumption, particularly red wine, may have benefits for cardiovascular health. Red wine contains a variety of bioactive compounds, including polyphenols like phenolic ...
  • Moderate-vigorous physical activity across body mass index in females: moderating effect of endocannabinoids and temperament
    Fernández Aranda, Fernando; Sauchelli, Sarah; Pastor, Antonio; González, Marcela L.; Torre Fornell, Rafael de la; Granero, Roser; Jiménez Murcia, Susana; Baños, Rosa M.; Botella, Cristina; Fernández Real, Jose M.; Fernández García, José C.; Frühbeck, Gema; Gómez Ambrosi, Javier; Rodríguez, Roser; Tinahones Madueño, Francisco José; Arcelus, Jon; Fagundo, Ana B.; Agüera, Zaida; Miró, Jordi; Casanueva, Felipe F. (Public Library of Science (PLoS), 2014)
    Background: Endocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females. The aims of this cross-sectional ...
  • Modification of high-density lipoprotein functions by diet and other lifestyle changes: a systematic review of randomized controlled trials
    Sanllorente Melenchón, Albert; Lassale, Camille; Soria-Florido, Maria; Castañer, Olga; Fitó Colomer, Montserrat; Hernáez, Álvaro (MDPI, 2021)
    High-density lipoprotein (HDL) functional traits have emerged as relevant elements that may explain HDL antiatherogenic capacity better than HDL cholesterol levels. These properties have been improved in several lifestyle ...
  • Modification of the hybrid anatomic technique for anterior cruciate ligament reconstruction in pediatric patients
    Erquicia, Juan Ignacio; Ibañez, Maximiliano; Espinoza-Von Bischhoffshausen, Ricardo; Acuña, Gabriel; Pelfort López, Javier; Monllau García, Juan Carlos (Elsevier, 2020)
    The incidence of anterior cruciate ligament (ACL) lesions with Tanner stage ≤4 has been increasing in children. To stabilize the knee, different surgical techniques have been developed for ACL reconstruction in the pediatric ...
  • Modification over time of pulse wave velocity parallel to changes in aortic BP, as well as in 24-h ambulatory brachial BP.
    Oliveras, Anna; Segura, Julián; Suárez, Carmen; García-Ortiz, Luis; Abad-Cardiel, María; Vigil, Luis; Gómez-Marcos, Manuel A.; Sans Atxer, Laia; Martell-Claros, Nieves; Ruilope, Luis Miguel; Sierra, Alejandro de la; RESCEN Study (Nature Publishing Group, 2016)
    Arterial stiffness as assessed by carotid-femoral pulse wave velocity (cfPWV) is a marker of preclinical organ damage and a predictor of cardiovascular outcomes, independently of blood pressure (BP). However, limited ...
  • Modified WHODAS-II provides valid measure of global disability but filter items increased skewness
    Korff, Michael von; Crane, Paul K.; Alonso Caballero, Jordi; Vilagut Saiz, Gemma, 1975-; Angermeyer, Matthias C.; Bruffaerts, Ronny; Girolamo, Giovanni de; Gureje, Oye; de Graaf, Ron; Huang, Yueqin; Iwata, Noboru; Karam, Elie G.; Kovess, Viviane; Lara, Carmen; Levinson, Daphna; Posada Villa, José; Scott, Kate M.; Ormel, Johan (Elsevier, 2008)
    OBJECTIVE: The WHODAS-II was substantially modified for use in the World Mental Health Surveys. This article considers psychometric properties and implications of filter items used to reduce respondent burden of the modified ...
  • Modulation of Higher-Order Olfaction Components on Executive Functions in Humans.
    Fagundo, Ana B.; Jiménez Murcia, Susana; Giner Bartolomé, Cristina; Anisul Islam, Mohammed; Torre Fornell, Rafael de la; Pastor, Antonio; Casanueva, Felipe F.; Crujeiras, Ana B.; Granero, Roser; Baños, Rosa M.; Botella, Cristina; Fernández Real, Jose M.; Frühbeck, Gema; Gómez Ambrosi, Javier; Menchón, José M.; Tinahones Madueño, Francisco José; Fernández Aranda, Fernando (Public Library of Science, 2015)
    The prefrontal (PFC) and orbitofrontal cortex (OFC) appear to be associated with both executive functions and olfaction. However, there is little data relating olfactory processing and executive functions in humans. The ...
  • Modulation of irisin and physical activity on executive functions in obesity and morbid obesity
    Fagundo, Ana B.; Torre Fornell, Rafael de la; Fernández Aranda, Fernando (Nature Publishing Group, 2016)
    Whether the executive profile is different between obesity (OB) and morbid obesity (MO) remains unclear. Recent evidence suggests that physical activity (PA) can act as a cognitive enhancer. Irisin is a recently discovered ...
  • Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model
    Ranea-Robles, Pablo; Galino, Jorge; Espinosa Blay, Lluís; Schlüter, Agatha; Ruiz, Montserrat; Calingasan, Noel Ylagan; Villarroya, Francesc; Naudí, Alba; Pamplona, Reinald; Ferrer, Isidre; Beal, M. Flint; Portero Otín, Manuel; Fourcade, Stéphane; Pujol, Aurora, 1968- (Wiley, 2022)
    Aims: Mitochondrial dysfunction and inflammation are at the core of axonal degeneration in several multifactorial neurodegenerative diseases, including multiple sclerosis, Alzheimer's disease, and Parkinson's disease. The ...
  • Modulation of Nrf2 by olive oil and wine polyphenols and neuroprotection
    Martínez-Huélamo, Miriam; Rodríguez-Morató, Jose, 1987-; Boronat Rigol, Anna, 1990-; Torre Fornell, Rafael de la (MDPI, 2017)
    Strong adherence to a Mediterranean diet is associated with improved cognitive function and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources of polyphenols which are responsible in ...
  • Modulation of telomere length by mediterranean diet, caloric restriction, and exercise: results from PREDIMED-Plus Study
    Fernández de la Puente, María; Hernández-Alonso, Pablo; Canudas i Puig, Sílvia; Martí, Amelia; Fitó Colomer, Montserrat; Razquin, Cristina; Salas Salvadó, Jordi (MDPI, 2021)
    Telomere length (TL) has been associated with aging and is determined by lifestyle. However, the mechanisms by which a dietary pattern such as the Mediterranean diet (MedDiet) affects TL homeostasis are still unknown. Our ...
  • Modulation of the colon cancer cell phenotype by pro-inflammatory macrophages: A preclinical model of surgery-associated inflammation and tumor recurrence
    Marcuello, María; Mayol Girbau, Xavier; Felipe-Fumero, Eloísa; Costa, Jaume; López-Hierro, Laia; Salvans Ruiz, Silvia; Alonso Gonçalves, Sandra; Pascual Damieta, Marta; Grande Posa, Luís; Pera Roman, Miguel (Public Library of Science (PLoS), 2018)
    Peritoneal infection after colorectal cancer surgery is associated with a higher rate of tumor relapse. We have recently proposed that soluble inflammatory factors released in response to a postoperative infection enhance ...
  • Modulation of the endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on executive functions in humans
    Fagundo, Ana B.; Torre Fornell, Rafael de la; Jiménez Murcia, Susana; Agüera, Zaida; Pastor, Antonio; Casanueva, Felipe F.; Granero, Roser; Baños, Rosa M.; Botella, Cristina; de Pino Gutiárrez, Amparo; Fernández Real, Jose M.; Fernández García, José C.; Frühbeck, Gema; Gómez Ambrosi, Javier; Menchón, José M.; Moragrega, Inés; Rodríguez, Roser; Tárrega, Salomé; Tinahones Madueño, Francisco José; Fernández Aranda, Fernando (Public Library of Science (PLoS), 2013)
    Animal studies point to an implication of the endocannabinoid system on executive functions. In humans, several studies have suggested an association between acute or chronic use of exogenous cannabinoids (Δ9-tetrahydrocannabinol) ...

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