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Browsing Articles (Barcelona Institute for Global Health (ISGlobal) – Campus Mar) by Issue Date

Browsing Articles (Barcelona Institute for Global Health (ISGlobal) – Campus Mar) by Issue Date

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  • Creating a transatlantic research enterprise for preventing Alzheimer's disease
    Khachaturian, Zaven; Camí, Jordi, 1952-; Andrieu, Sandrine; Avila, Jesús; Boada, Mercè; Breteler, Monique; Froelich, Lutz; Gauthier, Serge; Gómez-Isla, Teresa; Khachaturian, Ara S.; Kuller, Lewis H.; Larson, Eric B.; Lopez, Oscar L.; Martinez-Lage, José Manuel; Petersen, Ronald C.; Schellenberg, Gerard D.; Sunyer Deu, Jordi; Vellas, Bruno; Bain, Lisa J. (Elsevier, 2009)
    In recognition of the global problem posed by Alzheimer's disease and other dementias, an international think-tank meeting was convened by Biocat, the Pasqual Maragall Foundation, and the Lou Ruvo Brain Institute in February ...
  • Characteristics of patients admitted for the first time for COPD exacerbation
    Balcells Vilarnau, Eva, 1967-; Antó i Boqué, Josep Maria; Gea Guiral, Joaquim; Gómez, Federico P.; Rodríguez, Esther; Marin, Alicia; Ferrer, Antoni-Lluc, 1942-; De Batlle, Jordi; Farrero, Eva; Benet, Marta; Orozco Levi, Mauricio; Ferrer, Jaume; Agustí, Alvar; Gáldiz, Juan B.; Belda, José; García Aymerich, Judith (Elsevier, 2009)
    BACKGROUND: This study describes the characteristics of a large sample of patients hospitalised for the first time for a chronic obstructive pulmonary disease (COPD) exacerbation. METHODS: All subjects first admitted for ...
  • Traffic-related air pollution, oxidative stress genes, and asthma (ECHRS)
    Castro Giner, Francesc; Künzli, Nino; Jacquemin Leonard, Bénédicte; Forsberg, Bertil; Cid Ibeas, Rafael de; Sunyer Deu, Jordi; Jarvis, Deborah; Briggs, David; Vienneau, Danielle; Norbäck, Dan; Gonzalez, Juan Ramon; Guerra, Stefano; Janson, Christer; Antó i Boqué, Josep Maria; Wjst, Matthias; Heinrich, Joachim; Estivill, Xavier, 1955-; Kogevinas, Manolis (National Institute of Environmental Health Sciences (NIEHS), 2009)
    BACKGROUND: Traffic-related air pollution is related with asthma, and this association may be modified by genetic factors. OBJECTIVES: We investigated the role of genetic polymorphisms potentially modifying the association ...
  • Chlorination disinfection by-products in drinking water and congenital anomalies: review and meta-analyses
    Nieuwenhuijsen, Mark J.; Martinez Murciano, David; Grellier, James; Bennett, James; Best, Nicky; Iszatt, Nina; Vrijheid, Martine; Toledano, Mireille B. (National Institute of Environmental Health Sciences (NIEHS), 2009)
    OBJECTIVES: The aim of this study was to review epidemiologic evidence, provide summary risk estimates of the association between exposure to chlorination disinfection by-products (DBPs) and congenital anomalies, and provide ...
  • Power and sample size calculations for longitudinal studies comparing rates of change with a time-varying exposure
    Basagaña Flores, Xavier; Liao, Xiaomei; Spiegelman, Donna (Wiley-VCH Verlag, 2010)
    Existing study design formulas for longitudinal studies assume that the exposure is time invariant or that it varies in a manner that is controlled by design. However, in observational studies, the investigator does not ...
  • Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey
    Voll-Aanerud, Marianne; Eagan, Thomas ML; Plana, Estel; Omenaas, Ernst R.; Bakke, Per S; Svanes, Cecilie; Siroux, Valérie; Pin, Isabelle; Antó i Boqué, Josep Maria; Leynaert, Bénédicte (BioMed Central, 2010)
    Background: Respiratory symptoms are common in the general population, and their presence is related to Health-related quality of life (HRQoL). The objective was to describe the association of respiratory symptoms with ...
  • Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome
    Rodríguez Santiago, Benjamín; Malats i Riera, Núria; Rothman, Nathaniel; Armengol i Dulcet, Lluís; García Closas, Montserrat; Kogevinas, Manolis; Villa, Olaya; Hutchinson, Amy; Earl, Julie; Marenne, Gaëlle; Jacobs, Kevin; Rico, Daniel; Tardón, Adonina; Carrato, Alfredo; Thomas, Gilles; Valencia, Alfonso; Silverman, Debra T.; Real, Francisco X.; Chanock, Stephen J.; Pérez Jurado, Luis Alberto (Elsevier, 2010)
    Mosaicism is defined as the coexistence of cells with different genetic composition within an individual, caused by postzygotic somatic mutation. Although somatic mosaicism for chromosomal abnormalities is a well-established ...
  • Mass of intercostal muscles associates with risk of multiple exacerbations in COPD
    Güerri Fernández, Roberto; Gayete, Angel; Balcells Vilarnau, Eva, 1967-; Ramírez Sarmiento, Alba; Vollmer, Ivan; García Aymerich, Judith; Gea Guiral, Joaquim; Orozco Levi, Mauricio (Elsevier, 2010)
    BACKGROUND: The potential role of decreased respiratory muscle mass, if any, in mediating the susceptibility to exacerbation in COPD patients has not been determined. We hypothesized that a decrease in respiratory muscle ...
  • Factors affecting the relationship between psychological status and quality of life in COPD patients
    Balcells Vilarnau, Eva, 1967-; Gea Guiral, Joaquim; Ferrer, Jaume; Serra, Ignasi; Orozco Levi, Mauricio; Batlle Garcia, Jordi de, 1981-; Rodríguez, Esther; Benet, Marta; Donaire González, David; Antó i Boqué, Josep Maria; García Aymerich, Judith; PAC-COPD Study Group (BioMed Central, 2010)
    Background: This study aims to (i) evaluate the association between anxiety and depressive symptoms and health-related quality of life (HRQoL); and (ii) identify the effect modifiers of this relationship in patients with ...
  • A fast and accurate method to detect allelic genomic imbalances underlying mosaic rearrangements using SNP array data
    González Ruiz, Juan Ramón; Rodríguez Santiago, Benjamín; Cáceres, Alejandro; Pique Regi, Roger; Rothman, Nathaniel; Chanock, Stephen J.; Armengol i Dulcet, Lluís; Pérez Jurado, Luis Alberto (BioMed Central, 2011)
    Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal population. However its prevalence is poorly ...
  • Power and sample size calculations for longitudinal studies estimating a main effect of a time-varying exposure
    Basagaña Flores, Xavier; Spiegelman, Donna (SAGE Publications, 2011)
    Existing study design formulas for longitudinal studies have assumed that the exposure is time-invariant. We derived sample size formulas for studies comparing rates of change by exposure when the exposure varies with time ...
  • The effects of regular physical activity on adult-onset asthma incidence in women
    Benet, Marta; Varraso, Raphaëlle; Kauffmann, Francine; Romieu, Isabelle; Antó i Boqué, Josep Maria; Clavel Chapelon, Françoise; García Aymerich, Judith (Elsevier, 2011)
    BACKGROUND: Potential benefit of physical activity in asthma incidence is scarce and controversial. We aimed to assess the association between regular physical activity and adult-onset asthma. METHODS: We included 51,080 ...
  • Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition
    Morales, Eva; Bustamante Pineda, Mariona; González Ruiz, Juan Ramón; Guxens Junyent, Mònica; Torrent Quetglas, Maties; Mendez, Michelle A.; García Esteban, Raquel; Júlvez Calvo, Jordi; Forns i Guzman, Joan, 1981-; Vrijheid, Martine; Molto Puigmarti, Carolina; López Sabater, M. Carmen; Estivill, Xavier, 1955-; Sunyer Deu, Jordi (Public Library of Science (PLoS), 2011)
    Introduction: Breastfeeding effects on cognition are attributed to long-chain polyunsaturated fatty acids (LC-PUFAs), but controversy persists. Genetic variation in fatty acid desaturase (FADS) and elongase (ELOVL) enzymes ...
  • Ambient air pollution and risk of congenital anomalies: a systematic review and meta-analysis
    Vrijheid, Martine; Martinez Murciano, David; Manzanares-Laya, Sandra; Dadvand, Payam; Schembari, Anna, 1982-; Rankin, Judith; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences (NIEHS), 2011)
    OBJECTIVE: We systematically reviewed epidemiologic studies on ambient air pollution and congenital anomalies and conducted meta-analyses for a number of air pollutant-anomaly combinations. DATA SOURCES AND EXTRACTION: ...
  • Validity of instruments to measure physical activity may be questionable due to a lack of conceptual frameworks: a systematic review
    Gimeno Santos, Elena, 1980-; Frei, Anja; Dobbels, Fabienne; Rüdell, Katja; Puhan, Milo A.; García Aymerich, Judith; PROactive consortium (BioMed Central, 2011)
    Background: Guidance documents for the development and validation of patient-reported outcomes (PROs) advise the use of conceptual frameworks, which outline the structure of the concept that a PRO aims to measure. It is ...
  • Exposure to trihalomethanes through different water uses and birth weight, small for gestational age, and preterm delivery in Spain
    Villanueva Belmonte, Cristina; Gracia Lavedan, Esther; Ibarluzea, Jesús; Marina, Loreto Santa; Ballester Díez, Ferran; Llop, Sabrina; Tardón, Adonina; Fernandez, Mariana F.; Freire, Carmen; Goñi, Fernando; Basagaña Flores, Xavier; Kogevinas, Manolis; Grimalt Obrador, Joan; Sunyer Deu, Jordi (National Institute of Environmental Health Sciences (NIEHS), 2011)
    Background: Evidence associating exposure to water disinfection by-products with reduced birth weight and altered duration of gestation remains inconclusive. Objective: We assessed exposure to trihalomethanes (THMs) during ...
  • Climate extremes and the length of gestation
    Dadvand, Payam; Basagaña Flores, Xavier; Sartini, Claudio; Figueras, Francesc; Vrijheid, Martine; De Nazelle, Audrey; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences (NIEHS), 2011)
    Background: Although future climate is predicted to have more extreme heat conditions, the available evidence on the impact of these conditions on pregnancy length is very scarce and inconclusive. Objectives: We investigated ...
  • Residential exposure to outdoor air pollution during pregnancy and anthropometric measures at birth in a multicenter cohort in Spain
    Estarlich, Marisa; Ballester Díez, Ferran; Fernández Somoano, Ana; Aguilera Jiménez, Inmaculada, 1977-; Lertxundi, Aitana; Llop, Sabrina; Freire, Carmen; Tardón, Adonina; Basterrechea, Mikel; Sunyer Deu, Jordi; Iñiguez, Carmen (National Institute of Environmental Health Sciences (NIEHS), 2011)
    Background: A growing body of research suggests that prenatal exposure to air pollution may be harmful to fetal development. We assessed the association between exposure to air pollution during pregnancy and anthropometric ...
  • Systems medicine and integrated care to combat chronic noncommunicable diseases
    Bousquet, Jean; Antó i Boqué, Josep Maria; Auffray, Charles (BioMed Central, 2011)
    We propose an innovative, integrated, cost-effective health system to combat major non-communicable diseases (NCDs), including cardiovascular, chronic respiratory, metabolic, rheumatologic and neurologic disorders and ...
  • Common variants at 12q15 and 12q24 are associated with infant head circumference
    Taal, H. Rob; Guxens Junyent, Mònica; Sunyer Deu, Jordi; Estivill, Xavier, 1955-; Jaddoe, Vincent W. V. (Nature Research, 2012)
    To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy ...

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