• Development of computational sequence analysis for the characterization of Hepatitis E in Catalonia

  Juliachs Torroella, Gisela (2024)

  Hepatitis E virus (HEV) is a zoonotic virus that causes acute hepatitis with increasing incidence in humans in Europe which is mainly transmitted by the consumption of undercooked pig meat. Zoonotic genotypes HEV-3 and ...
• G2019S mutation in the LRRK2 gene increases endosomal recruitment in iPSC-derived microglia

  Homet i Pagès, Marcel (2024)

  Parkinson’s disease (PD) is an uncurable neurodegenerative disorder associated with progressive death of dopaminergic neurons and formation of Lewy’s Bodies, containing α-synuclein. Growing evidence suggests that PD ...
• Toolkit development for identification of GABAergic neuronal subpopulation and conditional control of ectopic gene expression

  Sanmartín Cerrato, Victoria (2024)

  The hindbrain is the most posterior part of the vertebrate brain. This evolutionarily ancient region contains distinct progenitor cell populations that will give rise to different neuronal identities. Neurogenesis starts ...
• Investigating the role of fgf13 in the statoacoustic ganglion morphogenesis in Danio rerio

  Barbero Durán, Nuria Mei (2024)

  The statoacoustic ganglion (SAG) is the inner ear sensory ganglion, composed of bipolar neurons that send projections to the hair cells of the inner ear and the hindbrain. Fibroblast growth factor 13 (fgf13), a ...
• Technical and clinical validation of glial reactivity biomarkers sTREM2 and YKL-40 in Alzheimer’s disease

  Sambola Lloveras, Berta (2024)

  Glial reactivity plays an important role in the pathogenesis of Alzheimer’s disease (AD). Biomarkers associated with this process have the potential for understanding AD pathogenesis and facilitating the development of ...
• Impact of the COVID-19 pandemic on sickness absence rates in healthcare workers: a retrospective cohort study in a Spanish hospital

  López Millán, Brais (2023)

  The COVID-19 pandemic has affected the working conditions and social demands of healthcare workers (HCWs). This study focuses on analyzing sickness absence rates among HCWs in a Spanish hospital from 2018 to 2022, considering ...
• Socioeconomic determinants of early neurodevelopment

  Vallet Casadevall, Julieta (2023)

  Socioeconomic status (SES) can be determinant for human health. Through different mechanisms, a person’s educational level, occupational status and income can define their physical and mental well-being. Considering that ...
• Assessment of the optical genome mapping technique in splenic marginal zone lymphoma: a comparison with cytogenomic data

  Teixidó Mulet, Mar (2023)

  Splenic marginal zone lymphoma (SMZL) is a genetically heterogeneous entity, entailing the need for further genetic characterization to deepen the knowledge of its prognosis and optimize its diagnosis. Karyotype and FISH ...
• Optimization of sTREM2 ELISA to understand the role of microglia in Alzheimer's disease

  Miret Milian, Maria (2023)

  Triggering receptor expressed on myeloid cells 2 (TREM2), a microglial receptor, plays a crucial role in the innate immune response in Alzheimer's disease (AD), aiding in the clearance of amyloid beta plaques and preventing ...
• Hindbrain rhombomere centers harbor an heterogenous population of dividing progenitors

  Hernández Martin, Ariadna (2023)

  During embryonic development, tissue growth and morphogenesis are interconnected processes and their regulation is essential to correctly develop an organism. This regulation involves the controlled production of different ...
• De la neurociència a les aules: impacte de les competències socioemocionals en la creativitat i la cognició

  Pocurull Masferrer, Aina (2022)

  Les emocions tenen un impacte extens i substancial en els processos cognitius, i el seu paper en la cognició i la creativitat és estudiat per diverses línies de recerca, des de l’àmbit educatiu fins al camp de la neurociència. ...
• Study of the mechanism underlying the effect of 5-HT in microglial processes motility

  del Río i Torné, Carla (2022-10-26)

  Microglia, the brain's resident macrophages, have a distinct ramified morphology orchestrated by repeated cycles of extension and retraction of their long thin processes, allowing them to continuously monitor their ...
• Characterizing cortical bioenergetics in a mouse model of Alzheimer’s disease

  Ausellé Bosch, Sira (2022-10-18)

  Alzheimer's Disease (AD) currently represents the most common neurodegenerative disease worldwide. The complete underlying mechanisms of its physiopathology are still unknown, but brain bioenergetics and the endocannabinoid ...
• Aturem la transmissió per mosquits: disseny d’un projecte - a partir de la Guia ABPxODS - pel desenvolupament de les competències clau per a la sostenibilitat

  Magrinyà Estrada, Joan (2022-07-27)

  Els problemes d’abast mundial actuals exigeixen un canvi urgent en la nostra manera de pensar i actuar. Per aquest motiu, cal entendre l’educació com un instrument essencial per la transformació social cap a la consecució ...
• Global prevalence and incidence of Alzheimer’s disease and mild cognitive impairment

  Díaz Guindo, Marta (2021)

  Alzheimer’s disease (AD) is the most prevalent cause of dementia worldwide. AD is characterized histopathologically by senile plaques composed of amyloid β-peptide (Aβ) and neurofibrillary tangles consisting of aggregated ...
• Elucidating the pathophysiological role of the apoptosis inducing factor 1 (AIF1) in Alzheimer's disease: a review of its participation in other pathologies

  Solé Ariza, Aina (2021)

  Alzheimer’s disease (AD) is the most common cause of age-related dementia, whose progression and development are explained by two well-based hypotheses. The amyloid cascade hypothesis proposes the aggregation of the amyloid ...
• Study of the molecular basis of congenital disorders of glycosylation using yeast as a model organism

  Guiu Gonzalez, Neus (2021)

  Congenital Disorders of Glycosylation (CDG) are a group of inherited human disorders caused by defects on protein glycosylation. Rft1-CDG is a form of CDG caused by mutations in the gene RFT1. Rft1 is a conserved protein ...
• Inhibition of TELO2 sensitizes colorectal cancer cells to chemotherapies

  Ortiz Gràcia, Alba (2019)

  Colorectal cancer is the 2nd most killing cancer around the world. Because treatments generally involve DNA damage, high toxicity and undesirable effects are frequently observed, which lead to treatment suspension. Moreover, ...
• The role of the neuroimmune system in the pathogenesis of fetal alcohol spectrum disorders

  Sopena Rios, Maria (2020)

  Fetal alcohol spectrum disorders (FASD) results from maternal consumption of alcohol during pregnancy. Yet preventable, it still is very prevalent as it is estimated that 50% of the women of childbearing age consume alcohol ...
• Antimicrobial stewardship strategies against extended-spectrum β-lactamase-carrying enterobacterales: a review

  Rovira i Plujà, Jana (2021)

  Multidrug-resistant and extremely-drug resistant (MDR/XDR) Gram-negative bacteria (GNB) are responsible of most healthcare-associated infections worldwide. Antimicrobial stewardship (AMS) and infection control strategies ...

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