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Visualitza Barcelona Institute for Global Health (ISGlobal) – Campus Mar per matèria

Visualitza Barcelona Institute for Global Health (ISGlobal) – Campus Mar per matèria "Omics"

Ara mostrant els elements 1-6 de 6

Applying the exposome concept in birth cohort research: a review of statistical approaches

Santos, Susana; Maitre, Léa; Warembourg, Charline; Agier, Lydiane; Richiardi, Lorenzo; Basagaña Flores, Xavier; Vrijheid, Martine (Springer, 2020)

The exposome represents the totality of life course environmental exposures (including lifestyle and other non-genetic factors), from the prenatal period onwards. This holistic concept of exposure provides a new framework ...
Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort

Robinson, Oliver; Lau, Chung-Ho E.; Joo, Sungyeon; Andrušaitytė, Sandra; Borràs, Eva; Prado Bert, Paula de; Chatzi, Lida Vaia; Keun, Hector C.; Gražulevičienė, Regina; Gutzkow, Kristine B.; Maitre, Léa; Martens, Dries S.; Sabidó Aguadé, Eduard, 1981-; Siroux, Valérie; Urquiza, José M.; Vafeiadi, Marina, 1983-; Wright, John; Nawrot, Tim S.; Bustamante Pineda, Mariona; Vrijheid, Martine (eLife, 2023)

Background: While biological age in adults is often understood as representing general health and resilience, the conceptual interpretation of accelerated biological age in children and its relationship to development ...
Human Early Life Exposome (HELIX) study: a European population-based exposome cohort

Maitre, Léa; De Bont, Jeroen, 1989-; Casas Sanahuja, Maribel; Robinson, Oliver; Basagaña Flores, Xavier; Borràs, Eva; Bustamante Pineda, Mariona; de Castro, Montserrat; Donaire González, David; Estivill, Xavier, 1955-; Fossati, Serena; González, Juan Ramón; Hernández-Ferrer, Carles; Júlvez Calvo, Jordi; Manzano Salgado, Cyntia Beatriz, 1987-; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; van Gent, Diana; Vives Usano, Marta, 1990-; Warembourg, Charline; Nieuwenhuijsen, Mark J.; Vrijheid, Martine (BMJ Publishing Group, 2018)

PURPOSE: Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and ...
In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children

Vives Usano, Marta, 1990-; Hernández-Ferrer, Carles; Maitre, Léa; Ruiz Arenas, Carlos, 1990-; Borràs, Eva; Casas Sanahuja, Maribel; Estivill, Xavier, 1955-; González, Juan Ramón; Sabidó Aguadé, Eduard, 1981-; Vrijheid, Martine; Bustamante Pineda, Mariona (BioMed Central, 2020)

Background: The adverse health effects of early life exposure to tobacco smoking have been widely reported. In spite of this, the underlying molecular mechanisms of in utero and postnatal exposure to tobacco smoke are only ...
Integrating -omics approaches into population-based studies of endocrine disrupting chemicals: A scoping review

Maitre, Léa; Jedynak, Paulina; Gallego, Marta; Ciaran, Laura; Audouze, Karine; Casas Sanahuja, Maribel; Vrijheid, Martine (Elsevier, 2023)

Health effects of endocrine disrupting chemicals (EDCs) are challenging to detect in the general population. Omics technologies become increasingly common to identify early biological changes before the apparition of ...
Performance of approaches relying on multidimensional intermediary data to decipher causal relationships between the exposome and health: A simulation study under various causal structures

Cadiou, Solène; Basagaña Flores, Xavier; González, Juan Ramón; Lepeule, Johanna; Vrijheid, Martine; Siroux, Valérie; Slama, Rémy (Elsevier, 2021)

Challenges in the assessment of the health effects of the exposome, defined as encompassing all environmental exposures from the prenatal period onwards, include a possibly high rate of false positive signals. It might be ...