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Browsing Center for Genomic Regulation (CRG) by Subject "Whole-genome bisulfite sequencing (WGBS)"

Browsing Center for Genomic Regulation (CRG) by Subject "Whole-genome bisulfite sequencing (WGBS)"

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  • Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson's disease patients
    Fernández-Santiago, Ruben; Merkel, Angelika; Castellano, Giancarlo; Heath, Simon; Raya Chamorro, Ángel; Tolosa, Eduard; Martí, Maria José; Consiglio, Antonella; Ezquerra, Mario (BioMed Central, 2019)
    Background: Parkinson’s disease (PD) is characterized by the loss of midbrain dopaminergic neurons (DAn). Previously, we described the presence of DNA hyper- and hypo-methylation alterations in induced pluripotent stem ...

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