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Browsing Center for Genomic Regulation (CRG) by Subject "Transcriptome"

Browsing Center for Genomic Regulation (CRG) by Subject "Transcriptome"

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  • Cowled, Christopher; Stewart, Cameron R; Likic, Vladimir A; Friedländer, Marc R.; Tachedjian, Mary; Jenkins, Kristie A; Tizard, Mark L; Cottee, Pauline; Marsh, Glenn A; Zhou, Peng; Baker, Michelle L; Bean, Andrew G; Wang, Lin-fa (BioMed Central, 2014)
    Background: Bats are a major source of new and emerging viral diseases. Despite the fact that bats carry and shed highly pathogenic viruses including Ebola, Nipah and SARS, they rarely display clinical symptoms of infection. ...
  • Lund, Carina; Yellapragada, Venkatram; Vuoristo, Sanna; Balboa, Diego; Trova, Sara; Allet, Cecile; Eskici, Nazli; Pulli, Kristiina; Giacobini, Paolo; Tuuri, Timo; Raivio, Taneli (Company of Biologists, 2020)
    Gonadotropin-releasing hormone (GnRH) neurons provide a fundamental signal for the onset of puberty and subsequent reproductive functions by secretion of gonadotropin-releasing hormone. Their disrupted development or ...
  • Grassi, Luigi; Ullrich, Sebastian, 1984-; Merkel, Angelika; Gut, Marta; Heath, Simon; Gut, Ivo Glynne; Kuijpers, Taco W. (Elsevier, 2018)
    Neutrophils are short-lived blood cells that play a critical role in host defense against infections. To better comprehend neutrophil functions and their regulation, we provide a complete epigenetic overview, assessing ...
  • Elsik, Christine G; Cámara, Francisco; Honey Bee Genome Sequencing Consortium (BioMed Central, 2014)
    Background: The first generation of genome sequence assemblies and annotations have had a significant impact upon our understanding of the biology of the sequenced species, the phylogenetic relationships among species, the ...
  • Vlasova, Anna; Capella Gutiérrez, Salvador Jesús, 1985-; Erb, Ionas; Cámara, Francisco; Prieto Barja, Pablo, 1986-; Kedra, Darek; González Navarrete, Irene, 1983-; Cozzuto, Luca; Gómez Garrido, Jèssica; Aguilar Morón, María Asunción; Andreu Somavilla, Núria; Zehnsdorf, Maik; Alioto, Tyler; Notredame, Cedric; Gabaldón Estevan, Juan Antonio, 1973-; Guigó Serra, Roderic (BioMed Central, 2016)
    Background: Legumes are the third largest family of angiosperms and the second most important crop class. Legume genomes have been shaped by extensive large-scale gene duplications, including an approximately 58 million ...
  • Bofill-De Ros, Xavier; Santos, Mónica; Vila-Casadesús, Maria; Villanueva, Eneko; Andreu Somavilla, Núria; Dierssen, Mara; Fillat i Fonts, Cristina (BioMed Central, 2015)
    Background. Down syndrome (DS) or trisomy 21 is the result of a genetic dosage imbalance that translates in a broad clinical spectrum. A major challenge in the study of DS is the identification of functional genetic elements ...
  • Ounzain, Samir; Micheletti, Rudi; Beckmann, Tal; Schroen, Blanche; Alexanian, Michael; Pezzuto, Iole; Crippa, Stefania; Nemir, Mohamed; Sarre, Alexandre; Johnson, Rory; Dauvillier, Jérôme; Burdet, Frédéric; Ibberson, Mark; Guigó Serra, Roderic; Xenarios, Ioannis; Heymans, Stephane; Pedrazzini, Thierry (Oxford University Press, 2015)
    Aim: Heart disease is recognized as a consequence of dysregulation of cardiac gene regulatory networks. Previously, unappreciated components of such networks are the long non-coding RNAs (lncRNAs). Their roles in the heart ...
  • Arranz, Juan; Balducci, Elisa, 1981-; Arató, Krisztina, 1981-; Sánchez-Elexpuru, Gentzane; Najas Sales, Sònia, 1985-; Parras, Alberto; Rebollo, Elena; Pijuan, Isabel; Erb, Ionas; Verde, Gaetano; Sahún, Ignasi; Barallobre, María José; Lucas, José J.; Sánchez, Marina P.; de la Luna, Susana; Arbonés de Rafael, Maria Lourdes, 1959- (Elsevier, 2019)
    Autism spectrum disorders are early onset neurodevelopmental disorders characterized by deficits in social communication and restricted repetitive behaviors, yet they are quite heterogeneous in terms of their genetic basis ...
  • Mathers, Thomas C.; Gabaldón Estevan, Juan Antonio, 1973-; Julca, Irene; Loska, Damian; Hogenhout, Saskia A. (BioMed Central, 2017)
    BACKGROUND: The prevailing paradigm of host-parasite evolution is that arms races lead to increasing specialisation via genetic adaptation. Insect herbivores are no exception and the majority have evolved to colonise a ...
  • Zubovic, Lorena; Piazza, Silvano; Tebaldi, Toma; Cozzuto, Luca; Palazzo, Giuliana; Sidarovich, Viktoryia; Sanctis, Verónica de; Bertorelli, Roberto; Lammens, Tim; Hofmans, Mattias; Moerloose, Bárbara de; Ponomarenko, Julia; Pigazzi, Martina; Masetti, Riccardo; Mecucci, Cristina; Basso, Giuseppe; Macchi, Paolo (BioMed Central, 2020)
    Pediatric myelodysplastic syndrome (PMDS) is a very rare and still poorly characterized disorder. In this work, we identified novel potential targets of PMDS by determining genes with aberrant expression, which can be ...
  • García Pérez, Raquel, 1989-; Ramirez, Jose Miguel; Ripoll Cladellas, Aida; Chazarra-Gil, Ruben; Oliveros, Winona; Soldatkina, Oleksandra; Bosio, Mattia; Rognon, Paul Joris; Capella Gutiérrez, Salvador Jesús, 1985-; Calvo, Miquel (Calvo Llorca); Reverter, Ferran; Guigó Serra, Roderic; Aguet, François; Ferreira, Pedro G.; Ardlie, Kristin G.; Melé Messeguer, Marta, 1982- (Elsevier, 2022)
    Understanding the consequences of individual transcriptome variation is fundamental to deciphering human biology and disease. We implement a statistical framework to quantify the contributions of 21 individual traits as ...

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