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Browsing Center for Genomic Regulation (CRG) by Subject "Single-molecule real-time sequencing"

Browsing Center for Genomic Regulation (CRG) by Subject "Single-molecule real-time sequencing"

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  • Exploiting single-molecule transcript sequencing for eukaryotic gene prediction
    Minoche, André E.; Dohm, Juliane C.; Schneider, Jessica; Holtgräwe, Daniela; Viehöver, Prisca; Montfort, Magda; Sörensen, Thomas Rosleff; Weisshaar, Bernd; Himmelbauer, Heinz (BioMed Central, 2015)
    We develop a method to predict and validate gene models using PacBio single-molecule, real-time (SMRT) cDNA reads. Ninety-eight percent of full-insert SMRT reads span complete open reading frames. Gene model validation ...

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