Browsing Center for Genomic Regulation (CRG) by Subject "Kinesin"

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APC couples neuronal mRNAs to multiple kinesins, EB1, and shrinking microtubule ends for bidirectional mRNA motility

Baumann, Sebastian; Grawenhoff, Julia; Rodrigues, Elsa C.; Speroni, Silvia; Gili, Maria; Komissarov, Artem, 1992-; Maurer, Sebastian (National Academy of Sciences, 2022)

Understanding where in the cytoplasm mRNAs are translated is increasingly recognized as being as important as knowing the timing and level of protein expression. mRNAs are localized via active motor-driven transport along ...
Mammalian neuronal mRNA transport complexes: the few knowns and the many unknowns

Rodrigues, Elsa C.; Grawenhoff, Julia; Baumann, Sebastian; Lorenzon, Nicola; Maurer, Sebastian (Frontiers, 2021)

Hundreds of messenger RNAs (mRNAs) are transported into neurites to provide templates for the assembly of local protein networks. These networks enable a neuron to configure different cellular domains for specialized ...

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