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Browsing Center for Genomic Regulation (CRG) by Subject "Behavioural genetics"

Browsing Center for Genomic Regulation (CRG) by Subject "Behavioural genetics"

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  • A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling
    Li, Dong; Chang, Xiao; Connolly, John J.M.; Tian, Lifeng; Liu, Yichuan; Bhoj, Elizabeth J.; Robinson, Nora; Abrams, Debra J.; Li, Yun Rose; Bradfield, Jonathan P.; Kim, Cecilia E.; Li, Jin; Wang, Fengxiang; Snyder, James; Lemma, Maria; Hou, Cuiping; Wei, Zhi; Guo, Yiran; Qiu, Haijun; Mentch, Frank D.; Thomas, Kelly A.; Chiavacci, Rosetta M.; Cone, Roger D.; Li, Bingshan; Sleiman, Patrick M.A.; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Price Foundation Collaborative Group; Hakonarson, Hakon (Nature Publishing Group, 2017)
    We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using a stringently defined phenotype. Analysis of phenotypic variability led to the identification of a specific genetic risk factor that ...
  • A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction
    Domingo Rodriguez, Laura, 1992-; Ruiz de Azua, Iñigo; Domínguez, Eduardo; Senabre, Eric; Serra, Irene; Kummer, Sami, 1985-; Navandar, Mohit; Baddenhausen, Sarah; Hofmann, Clementine; Andero, Raül; Gerber, Susanne; Navarrete, Marta; Dierssen, Mara; Lutz, Beat; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Nature Research, 2020)
    Food addiction is linked to obesity and eating disorders and is characterized by a loss of behavioral control and compulsive food intake. Here, using a food addiction mouse model, we report that the lack of cannabinoid ...
  • FOXP2 variation in great ape populations offers insight into the evolution of communication skills
    Staes, Nicky; Sherwood, Chet C.; Wright, Katharine; de Manuel, Marc; Guevara, Elaine E.; Marquès i Bonet, Tomàs, 1975-; Krützen, Michael; Massiah, Michael; Hopkins, William D.; Ely, John J.; Bradley, Brenda J. (Nature Publishing Group, 2017)
    The gene coding for the forkhead box protein P2 (FOXP2) is associated with human language disorders. Evolutionary changes in this gene are hypothesized to have contributed to the emergence of speech and language in the ...
  • Gene-wide association study reveals RNF122 ubiquitin ligase as a novel susceptibility gene for attention deficit hyperactivity disorder
    Garcia Martínez, Iris; Sánchez-Mora, Cristina; Soler Artigas, María; Rovira, Paula; Pagerols, Mireia; Corrales, Montse; Calvo Sánchez, Eva; Richarte, Vanesa; Bustamante Pineda, Mariona; Sunyer Deu, Jordi; Cormand, Bru; Casas, Miguel; Ramos Quiroga, Josep Antoni; Ribasés, Marta (Nature Publishing Group, 2017)
    Attention Deficit Hyperactivity Disorder (ADHD) is a common childhood-onset neurodevelopmental condition characterized by pervasive impairment of attention, hyperactivity, and/or impulsivity that can persist into adulthood. ...

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